Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50030764
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301030(CHEMBL567679 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301027(CHEMBL582806 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301037(2-(5-tert-butylisoxazol-3-ylamino)-N-((2S,3S)-4-(4...)
Affinity DataIC50:  8.60nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301042(CHEMBL572097 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  10.1nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301028(CHEMBL569292 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  12.2nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301029(2-(3-chloro-5-(trifluoromethyl)pyridin-2-ylamino)-...)
Affinity DataIC50:  17.9nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301036(CHEMBL572271 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  19.5nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301031(CHEMBL567876 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  37.7nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301034(CHEMBL568849 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  46.1nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301035(CHEMBL584309 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  47.7nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301032(CHEMBL568094 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  49nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301033(CHEMBL567461 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  49.2nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301041(CHEMBL567513 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  97nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301042(CHEMBL572097 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  117nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301044(2-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)but...)
Affinity DataIC50:  132nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301045(2-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)but...)
Affinity DataIC50:  136nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301038(CHEMBL571831 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  186nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301040(CHEMBL567297 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  203nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301038(CHEMBL571831 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  234nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301037(2-(5-tert-butylisoxazol-3-ylamino)-N-((2S,3S)-4-(4...)
Affinity DataIC50:  254nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  285nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301039(CHEMBL584332 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  301nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301027(CHEMBL582806 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  322nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301030(CHEMBL567679 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  353nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301029(2-(3-chloro-5-(trifluoromethyl)pyridin-2-ylamino)-...)
Affinity DataIC50:  419nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301031(CHEMBL567876 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  547nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301028(CHEMBL569292 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  699nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301041(CHEMBL567513 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  1.41E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301044(2-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)but...)
Affinity DataIC50:  1.72E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301032(CHEMBL568094 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  1.83E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301027(CHEMBL582806 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301045(2-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)but...)
Affinity DataIC50:  2.31E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301043(CHEMBL569614 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  2.98E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301035(CHEMBL584309 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  3.21E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301034(CHEMBL568849 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  3.86E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301036(CHEMBL572271 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  5.16E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301039(CHEMBL584332 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  6.11E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301040(CHEMBL567297 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  1.33E+4nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301033(CHEMBL567461 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301043(CHEMBL569614 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  2.59E+4nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301044(2-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)but...)
Affinity DataIC50: >3.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301042(CHEMBL572097 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataEC50:  1.90nMAssay Description:Inverse agonist activity at human CB1 receptor assessed as forskolin-induced cAMP level by adenylyl cyclase activation flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301030(CHEMBL567679 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataEC50:  0.900nMAssay Description:Inverse agonist activity at human CB1 receptor assessed as forskolin-induced cAMP level by adenylyl cyclase activation flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301027(CHEMBL582806 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataEC50:  3.20nMAssay Description:Inverse agonist activity at human CB1 receptor assessed as forskolin-induced cAMP level by adenylyl cyclase activation flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataEC50:  2.40nMAssay Description:Inverse agonist activity at human CB1 receptor assessed as forskolin-induced cAMP level by adenylyl cyclase activation flash plate assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301037(2-(5-tert-butylisoxazol-3-ylamino)-N-((2S,3S)-4-(4...)
Affinity DataEC50:  3.5nMAssay Description:Inverse agonist activity at human CB1 receptor assessed as forskolin-induced cAMP level by adenylyl cyclase activation flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed