Compile Data Set for Download or QSAR
maximum 50k data
Found 112 Enz. Inhib. hit(s) with all data for entry = 50031846
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(CHEMBL1082381 | N-Hydroxy-4-{[4-(phenylthio)phenyl...)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(CHEMBL1082381 | N-Hydroxy-4-{[4-(phenylthio)phenyl...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320412(CHEMBL1084238 | N-hydroxy-4-(4-(4-(4-(trifluoromet...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320410(CHEMBL1084208 | N-hydroxy-4-(4-(4-(4-methoxyphenyl...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320393(4-(4-(4-(4-chlorophenyl)piperidin-1-yl)phenylsulfo...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320413(4-(4-(4-(4-chlorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(CHEMBL1082381 | N-Hydroxy-4-{[4-(phenylthio)phenyl...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320405(CHEMBL1085602 | N-hydroxy-4-(4-(4-phenylpiperazin-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(CHEMBL1082381 | N-Hydroxy-4-{[4-(phenylthio)phenyl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320411(CHEMBL1084209 | N-hydroxy-4-(4-(4-p-tolylpiperazin...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320393(4-(4-(4-(4-chlorophenyl)piperidin-1-yl)phenylsulfo...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320390(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-(trifluoromethy...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320406(4-(4-(4-(2-fluorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320389(1-cyclopropyl-N-hydroxy-4-(4-(4-phenylpiperazin-1-...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320413(4-(4-(4-(4-chlorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320391(CHEMBL1083932 | N-hydroxy-4-(4-(4-phenylpiperidin-...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320389(1-cyclopropyl-N-hydroxy-4-(4-(4-phenylpiperazin-1-...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320391(CHEMBL1083932 | N-hydroxy-4-(4-(4-phenylpiperidin-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320401(CHEMBL1082371 | N-hydroxy-4-(4-(4-(4-methoxy-2-met...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320407(CHEMBL1083906 | N-hydroxy-4-(4-(4-o-tolylpiperazin...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320409(CHEMBL1084206 | N-hydroxy-4-(4-(4-(3-methoxyphenyl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320408(4-(4-(4-(2-chlorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320398(CHEMBL1083322 | N-hydroxy-4-(4-(4-(2-hydroxyphenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320400(CHEMBL1082370 | N-hydroxy-4-(4-(4-(naphthalen-1-yl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320403(4-(4-(4-(2,5-dimethoxyphenyl)piperidin-1-yl)phenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320402(4-(4-(4-(2,4-dimethoxyphenyl)piperidin-1-yl)phenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320412(CHEMBL1084238 | N-hydroxy-4-(4-(4-(4-(trifluoromet...)
Affinity DataIC50:  12nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(CHEMBL1082381 | N-Hydroxy-4-{[4-(phenylthio)phenyl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320392(CHEMBL1084220 | N-hydroxy-4-(4-(4-(2-methoxyphenyl...)
Affinity DataIC50:  18nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320410(CHEMBL1084208 | N-hydroxy-4-(4-(4-(4-methoxyphenyl...)
Affinity DataIC50:  18nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(CHEMBL1082381 | N-Hydroxy-4-{[4-(phenylthio)phenyl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320417(CHEMBL1084207 | N-hydroxy-4-(4-(4-(3-(trifluoromet...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320406(4-(4-(4-(2-fluorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50:  21nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320405(CHEMBL1085602 | N-hydroxy-4-(4-(4-phenylpiperazin-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  25nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320396(CHEMBL1083007 | N-hydroxy-4-(4-(4-(2-(trifluoromet...)
Affinity DataIC50:  29nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320418(4-(4-(4-(2,4-dimethylphenyl)piperazin-1-yl)phenyls...)
Affinity DataIC50:  29nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320395(CHEMBL1083626 | N-hydroxy-4-(4-(4-o-tolylpiperidin...)
Affinity DataIC50:  33nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320390(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-(trifluoromethy...)
Affinity DataIC50:  33nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320399(4-(4-(4-(4'-fluorobiphenyl-2-yl)piperidin-1-yl)phe...)
Affinity DataIC50:  34nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320397(4-(4-(4-(2-ethoxyphenyl)piperidin-1-yl)phenylsulfo...)
Affinity DataIC50:  35nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320411(CHEMBL1084209 | N-hydroxy-4-(4-(4-p-tolylpiperazin...)
Affinity DataIC50:  35nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320408(4-(4-(4-(2-chlorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320394(4-(4-(4-(2-chlorophenyl)piperidin-1-yl)phenylsulfo...)
Affinity DataIC50:  43nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320409(CHEMBL1084206 | N-hydroxy-4-(4-(4-(3-methoxyphenyl...)
Affinity DataIC50:  49nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  59nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320404(CHEMBL1085748 | N-hydroxy-4-(4-(4-(5-isopropyl-2-m...)
Affinity DataIC50:  70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320398(CHEMBL1083322 | N-hydroxy-4-(4-(4-(2-hydroxyphenyl...)
Affinity DataIC50:  70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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