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Found 22 Enz. Inhib. hit(s) with all data for entry = 50032436
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329192((3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329187((3alpha,18beta,20beta)-3-Methoxyamino-11-oxo-olean...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329188((3beta,18beta,20beta)-3-Methoxyamino-11-oxo-olean-...)
Affinity DataIC50:  14.5nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329188((3beta,18beta,20beta)-3-Methoxyamino-11-oxo-olean-...)
Affinity DataIC50:  42.7nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329193((3beta,18beta,20beta)-3-Acetoxy-N-hydroxy-11-oxo-o...)
Affinity DataIC50:  61.1nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329187((3alpha,18beta,20beta)-3-Methoxyamino-11-oxo-olean...)
Affinity DataIC50:  61.9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329195((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihyd...)
Affinity DataIC50:  122nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  257nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329191((2S,4aS,6aS,6bR,8aR,12aS,12bR,14bR,E)-10-(methoxyi...)
Affinity DataIC50:  268nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329190((18beta,20beta)-3,11-Dioxo-olean-12-en-29-oic acid...)
Affinity DataIC50:  329nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329189((3beta,18beta,20beta)-3-(Acetylamino)-11-oxo-olean...)
Affinity DataIC50:  458nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329190((18beta,20beta)-3,11-Dioxo-olean-12-en-29-oic acid...)
Affinity DataIC50:  619nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329193((3beta,18beta,20beta)-3-Acetoxy-N-hydroxy-11-oxo-o...)
Affinity DataIC50:  626nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  778nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329189((3beta,18beta,20beta)-3-(Acetylamino)-11-oxo-olean...)
Affinity DataIC50:  825nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329194((3beta,18beta,20beta)-3-Hydroxy-N-methoxy-11-oxo-o...)
Affinity DataIC50:  929nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329192((3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329195((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihyd...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329191((2S,4aS,6aS,6bR,8aR,12aS,12bR,14bR,E)-10-(methoxyi...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329194((3beta,18beta,20beta)-3-Hydroxy-N-methoxy-11-oxo-o...)
Affinity DataIC50:  2.13E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)
Affinity DataIC50:  7.14E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB