Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50032667
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332946(CHEMBL1234724 | N-hydroxy-2-(N-(2-hydroxyethyl)-4-...)
Affinity DataKi:  1nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332948((R)-2-(N-((S)-2,3-dihydroxypropyl)-4-methoxyphenyl...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332952(CHEMBL1233772 | N-hydroxy-2-(N-(2-hydroxyethyl)bip...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332950((2R,3R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamid...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332952(CHEMBL1233772 | N-hydroxy-2-(N-(2-hydroxyethyl)bip...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  6nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332948((R)-2-(N-((S)-2,3-dihydroxypropyl)-4-methoxyphenyl...)
Affinity DataKi:  7nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332946(CHEMBL1234724 | N-hydroxy-2-(N-(2-hydroxyethyl)-4-...)
Affinity DataKi:  7.60nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332948((R)-2-(N-((S)-2,3-dihydroxypropyl)-4-methoxyphenyl...)
Affinity DataKi:  8nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  8nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataKi:  9nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  9nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332950((2R,3R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamid...)
Affinity DataKi:  10nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332950((2R,3R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamid...)
Affinity DataKi:  11nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332946(CHEMBL1234724 | N-hydroxy-2-(N-(2-hydroxyethyl)-4-...)
Affinity DataKi:  13nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  14.3nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  18nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  24nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332952(CHEMBL1233772 | N-hydroxy-2-(N-(2-hydroxyethyl)bip...)
Affinity DataKi:  31nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332948((R)-2-(N-((S)-2,3-dihydroxypropyl)-4-methoxyphenyl...)
Affinity DataKi:  32nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332951(2-(4-fluoro-N-(2-hydroxyethyl)phenylsulfonamido)-N...)
Affinity DataKi:  40nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332951(2-(4-fluoro-N-(2-hydroxyethyl)phenylsulfonamido)-N...)
Affinity DataKi:  46nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  48nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  60nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332952(CHEMBL1233772 | N-hydroxy-2-(N-(2-hydroxyethyl)bip...)
Affinity DataKi:  67nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332946(CHEMBL1234724 | N-hydroxy-2-(N-(2-hydroxyethyl)-4-...)
Affinity DataKi:  128nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  143nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332951(2-(4-fluoro-N-(2-hydroxyethyl)phenylsulfonamido)-N...)
Affinity DataKi:  151nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  160nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332951(2-(4-fluoro-N-(2-hydroxyethyl)phenylsulfonamido)-N...)
Affinity DataKi:  173nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataKi:  174nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  286nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332950((2R,3R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamid...)
Affinity DataKi:  287nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332948((R)-2-(N-((S)-2,3-dihydroxypropyl)-4-methoxyphenyl...)
Affinity DataKi:  344nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  742nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  823nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332950((2R,3R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamid...)
Affinity DataKi:  984nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332946(CHEMBL1234724 | N-hydroxy-2-(N-(2-hydroxyethyl)-4-...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332952(CHEMBL1233772 | N-hydroxy-2-(N-(2-hydroxyethyl)bip...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332951(2-(4-fluoro-N-(2-hydroxyethyl)phenylsulfonamido)-N...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed