Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50032863
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335865(6-Hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(naphthalen-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  205nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335868(6-Hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50:  214nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335870(6-Hydroxy-3-(1-(4-(6-methoxybenzo[d]thiazol-2-ylam...)
Affinity DataIC50:  217nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335864(3-(1-(4-(4-bromonaphthalen-1-ylamino)-4-oxobutyl)-...)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335865(6-Hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(naphthalen-...)
Affinity DataIC50:  335nMAssay Description:Inhibition of Shp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335866(6-hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(4-nitronaph...)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335865(6-Hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(naphthalen-...)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  378nMAssay Description:Inhibition of Shp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335868(6-Hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50:  408nMAssay Description:Inhibition of Shp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335868(6-Hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335865(6-Hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(naphthalen-...)
Affinity DataIC50:  410nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335869(6-hydroxy-3-(1-(4-oxo-4-(pyren-1-ylamino)butyl)-1H...)
Affinity DataIC50:  480nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335870(6-Hydroxy-3-(1-(4-(6-methoxybenzo[d]thiazol-2-ylam...)
Affinity DataIC50:  486nMAssay Description:Inhibition of Shp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335870(6-Hydroxy-3-(1-(4-(6-methoxybenzo[d]thiazol-2-ylam...)
Affinity DataIC50:  520nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335871(3-(1-(4-(4-chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335872(3-(1-(4-(6-fluorobenzo[d]thiazol-2-ylamino)-4-oxob...)
Affinity DataIC50:  610nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335873(6-hydroxy-3-(1-(4-(4-nitronaphthalen-1-ylamino)-4-...)
Affinity DataIC50:  640nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335874(6-hydroxy-3-(1-(4-oxo-4-(phenylamino)butyl)-1H-1,2...)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335875(3-(1-(4-(benzylamino)-4-oxobutyl)-1H-1,2,3-triazol...)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335868(6-Hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50:  681nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335876(3-(1-(4-(4-bromonaphthalen-1-ylamino)-4-oxobutyl)-...)
Affinity DataIC50:  710nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335877(3-(1-(4-(benzylamino)-4-oxobutyl)-1H-1,2,3-triazol...)
Affinity DataIC50:  740nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335878(6-hydroxy-3-(1-(2-(naphthalen-1-ylamino)-2-oxoethy...)
Affinity DataIC50:  770nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335870(6-Hydroxy-3-(1-(4-(6-methoxybenzo[d]thiazol-2-ylam...)
Affinity DataIC50:  877nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335879(3-(1-(4-(cyclohexylamino)-4-oxobutyl)-1H-1,2,3-tri...)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335880(6-hydroxy-3-(1-(3-(naphthalen-1-ylamino)-3-oxoprop...)
Affinity DataIC50:  910nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335881(3-(1-(4-(benzylamino)-4-oxobutyl)-1H-1,2,3-triazol...)
Affinity DataIC50:  970nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335882(6-hydroxy-3-(1-(4-oxo-4-(quinolin-8-ylamino)butyl)...)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335883(6-hydroxy-3-(1-(2-(naphthalen-1-ylamino)-2-oxoethy...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335884(6-hydroxy-3-(1-(3-(naphthalen-1-ylamino)-3-oxoprop...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335885(6-hydroxy-3-(1-(4-(4-nitronaphthalen-1-ylamino)-4-...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335886(6-hydroxy-3-(1-(6-(naphthalen-1-ylamino)-6-oxohexy...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335887(6-hydroxy-3-(1-(5-(naphthalen-1-ylamino)-5-oxopent...)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335888(6-hydroxy-3-(1-(5-(naphthalen-1-ylamino)-5-oxopent...)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335889(6-hydroxy-3-(1-(4-(2-nitrophenylamino)-4-oxobutyl)...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335890(6-hydroxy-3-(1-(6-(naphthalen-1-ylamino)-6-oxohexy...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335891(3-(1-(4-(cyclohexylamino)-4-oxobutyl)-1H-1,2,3-tri...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335892(6-hydroxy-3-(1-(4-oxo-4-(quinolin-8-ylamino)butyl)...)
Affinity DataIC50:  3.22E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335893(6-hydroxy-3-(1-(4-(naphthalen-2-ylamino)-4-oxobuty...)
Affinity DataIC50:  3.44E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibition of HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335865(6-Hydroxy-2-(4-methoxyphenyl)-3-(1-(4-(naphthalen-...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335894(6-hydroxy-3-(1-(4-(naphthalen-2-ylamino)-4-oxobuty...)
Affinity DataIC50:  3.84E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335868(6-Hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335896(CHEMBL1650918 | Methyl 3-(1-(4-(4-Chloronaphthalen...)
Affinity DataIC50:  4.86E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335897(6-hydroxy-3-(1-(3-(naphthalen-1-ylamino)-3-oxoprop...)
Affinity DataIC50:  5.02E+3nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335896(CHEMBL1650918 | Methyl 3-(1-(4-(4-Chloronaphthalen...)
Affinity DataIC50:  5.76E+3nMAssay Description:Inhibition of Shp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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