Compile Data Set for Download or QSAR
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Found 13 Enz. Inhib. hit(s) with all data for entry = 50032891
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336275(1-oxo-1,3,4,5,6,7,8,9-octahydrobenzo[c][1]oxacyclo...)
Affinity DataIC50:  580nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336276(1-oxo-1,3,4,5,6,7,8,9,10,11-decahydrobenzo[c][1]ox...)
Affinity DataIC50:  820nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336277(1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-benzo[c][1]oxa...)
Affinity DataIC50:  1.11E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336278((R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-b...)
Affinity DataIC50:  2.78E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336274(1-oxo-3,4,5,6,7,8,9,10,11,12-decahydro-1H-benzo[c]...)
Affinity DataIC50:  2.90E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336276(1-oxo-1,3,4,5,6,7,8,9,10,11-decahydrobenzo[c][1]ox...)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of progesterone receptor ligand binding domain expressed in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336274(1-oxo-3,4,5,6,7,8,9,10,11,12-decahydro-1H-benzo[c]...)
Affinity DataIC50:  3.22E+3nMAssay Description:Inhibition of progesterone receptor ligand binding domain expressed in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336279((R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-b...)
Affinity DataIC50:  6.51E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336278((R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-b...)
Affinity DataIC50:  8.36E+3nMAssay Description:Inhibition of ERalpha ligand binding domain expressed in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336280((R)-de-O-methyllasioplodin | CHEMBL1669749)
Affinity DataIC50:  8.93E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336274(1-oxo-3,4,5,6,7,8,9,10,11,12-decahydro-1H-benzo[c]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ERalpha ligand binding domain expressed in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336281((R,Z)-12,14-dimethoxy-3-methyl-3,4,5,6,9,10-hexahy...)
Affinity DataIC50:  1.66E+4nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50336282((R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-b...)
Affinity DataIC50:  3.17E+4nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed