TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of ASK1 (unknown origin) using biotin-MBP as substrate after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of ASK1 (unknown origin) using biotin-MBP as substrate after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of ASK1 (unknown origin) using biotin-MBP as substrate after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 457nMAssay Description:Inhibition of recombinant full length human His-tagged GSK3B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of human Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 617nMAssay Description:Inhibition of recombinant human GST-tagged RET cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 794nMAssay Description:Inhibition of PRKAA1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 832nMAssay Description:Inhibition of recombinant full length human His-tagged GSK3B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROCK1 catalytic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 5.37E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROCK1 catalytic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant full length human GST-tagged ITK expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ASK1 (unknown origin) using biotin-MBP as substrate after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of recombinant human GST-tagged MER cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of recombinant human GST-tagged MER cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of recombinant human GST-tagged RET cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of PRKAA1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <2.00E+4nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged RON cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged RON cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant full length human GST-tagged ITK expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ERBB4 cytoplasmic domain (708 to 993 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human His-tagged EPHA3 cytoplasmic domain (569 to 976 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human His-tagged EPHA3 cytoplasmic domain (569 to 976 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: <2.00E+4nMAssay Description:In vitro inhibition of human Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ERBB4 cytoplasmic domain (708 to 993 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ASK1 (unknown origin) using biotin-MBP as substrate after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 5.00E+5nMAssay Description:In vitro inhibition of human Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Inhibition of ASK1 (unknown origin) assessed as reduction in JNK phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Inhibition of ASK1 (unknown origin) assessed as reduction in JNK phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 99nMAssay Description:Inhibition of ASK1 (unknown origin) assessed as reduction in JNK phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Inhibition of ASK1 (unknown origin) assessed as reduction in JNK phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 65nMAssay Description:Inhibition of ASK1 (unknown origin) assessed as reduction in JNK phosphorylation by cell based assayMore data for this Ligand-Target Pair