Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50037794
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200833(CHEMBL373626 | N-((2S,3S)-4-(4-chlorophenyl)-3-phe...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200844(CHEMBL219480 | N-((2S,3S)-4-(4-chlorophenyl)-3-phe...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200836(CHEMBL387027 | N-[(1S,2S)-3-(4-chlorophenyl)-1-met...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200830(CHEMBL385033 | N-[(1S,2S)-3-(4-chlorophenyl)-1-met...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200839(CHEMBL385767 | N-[(1S,2S)-3-(4-chlorophenyl)-1-met...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200831(CHEMBL374791 | N-((2S,3S)-4-(4-chlorophenyl)-3-phe...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200838(CHEMBL217862 | N-((2S,3S)-4-(4-chlorophenyl)-3-phe...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200835(CHEMBL219188 | N-[3-(4-chlorophenyl)-1-methyl-2-ph...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200828(CHEMBL218649 | N-[(1R,2R)-3-(4-chlorophenyl)-1-met...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200842(CHEMBL374291 | N-[2,3-bis(4-chlorophenyl)-1-methyl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200837((1R,2R)-N-[2,3-bis(4-chlorophenyl)-1-methylpropyl]...)
Affinity DataIC50:  48nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200831(CHEMBL374791 | N-((2S,3S)-4-(4-chlorophenyl)-3-phe...)
Affinity DataIC50:  88nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200836(CHEMBL387027 | N-[(1S,2S)-3-(4-chlorophenyl)-1-met...)
Affinity DataIC50:  100nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200833(CHEMBL373626 | N-((2S,3S)-4-(4-chlorophenyl)-3-phe...)
Affinity DataIC50:  140nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200830(CHEMBL385033 | N-[(1S,2S)-3-(4-chlorophenyl)-1-met...)
Affinity DataIC50:  190nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200844(CHEMBL219480 | N-((2S,3S)-4-(4-chlorophenyl)-3-phe...)
Affinity DataIC50:  200nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200839(CHEMBL385767 | N-[(1S,2S)-3-(4-chlorophenyl)-1-met...)
Affinity DataIC50:  290nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  290nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200838(CHEMBL217862 | N-((2S,3S)-4-(4-chlorophenyl)-3-phe...)
Affinity DataIC50:  450nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataIC50:  600nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200835(CHEMBL219188 | N-[3-(4-chlorophenyl)-1-methyl-2-ph...)
Affinity DataIC50:  610nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200828(CHEMBL218649 | N-[(1R,2R)-3-(4-chlorophenyl)-1-met...)
Affinity DataIC50:  770nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200842(CHEMBL374291 | N-[2,3-bis(4-chlorophenyl)-1-methyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200837((1R,2R)-N-[2,3-bis(4-chlorophenyl)-1-methylpropyl]...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB2 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataEC50:  2.40nMAssay Description:Inverse agonist activity at human recombinant CB1 receptor assessed as inhibition of forskolin-induced cAMP production in CHO cellsMore data for this Ligand-Target Pair