Compile Data Set for Download or QSAR
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Found 33 Enz. Inhib. hit(s) with all data for entry = 50042948
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433602(CHEMBL2381980)
Affinity DataKi:  0.720nMAssay Description:Competitive inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433601(CHEMBL2381983)
Affinity DataKi:  1.40nMAssay Description:Competitive inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433604(CHEMBL2381986)
Affinity DataIC50:  3nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433605(CHEMBL2381975)
Affinity DataIC50:  3nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433601(CHEMBL2381983)
Affinity DataIC50:  3nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433611(CHEMBL2381979)
Affinity DataIC50:  3nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433609(CHEMBL2381982)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433608(CHEMBL2381984)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433604(CHEMBL2381986)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433615(CHEMBL2381976)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433607(CHEMBL2381985)
Affinity DataIC50:  5nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433610(CHEMBL2381981)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433606(CHEMBL2380329)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433601(CHEMBL2381983)
Affinity DataIC50:  7nMAssay Description:Inhibition of JAK2 TEL domain (unknown origin) transfected in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433601(CHEMBL2381983)
Affinity DataIC50:  8nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433603(CHEMBL2381987)
Affinity DataIC50:  15nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433603(CHEMBL2381987)
Affinity DataIC50:  17nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433614(CHEMBL2381977)
Affinity DataIC50:  20nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433605(CHEMBL2381975)
Affinity DataIC50:  20nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433602(CHEMBL2381980)
Affinity DataIC50:  20nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433613(CHEMBL1080151)
Affinity DataIC50:  25nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433615(CHEMBL2381976)
Affinity DataIC50:  30nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433612(CHEMBL2381978)
Affinity DataIC50:  37nMAssay Description:Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433608(CHEMBL2381984)
Affinity DataIC50:  45nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433609(CHEMBL2381982)
Affinity DataIC50:  87nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433607(CHEMBL2381985)
Affinity DataIC50:  95nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433611(CHEMBL2381979)
Affinity DataIC50:  229nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433610(CHEMBL2381981)
Affinity DataIC50:  262nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433606(CHEMBL2380329)
Affinity DataIC50:  262nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433601(CHEMBL2381983)
Affinity DataIC50:  370nMAssay Description:Inhibition of JAK3 TEL domain (unknown origin) transfected in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433612(CHEMBL2381978)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433614(CHEMBL2381977)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433613(CHEMBL1080151)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed