Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 1687
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM335698((R)-3-(3-Methyl-2-oxopiperidin-3-yl)-6-(5-methylqu...)
Affinity DataKi:  3.30nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM335700((R)-6-(5-Ethylquinolin-7-yl)-3-(3-methyl-2-oxopipe...)
Affinity DataKi:  4.60nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM335699((R)-3-(3-Methyl-2-oxopiperidin-3-yl)-6-(5-methylqu...)
Affinity DataKi:  7.20nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM335702((R)-6-(5-Cyclopropylquinolin-7-yl)-3-(3-methyl-2-o...)
Affinity DataKi:  7.30nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM335701((R)-6-(5-Chloroquinolin-7-yl)-3-(3-methyl-2-oxopip...)
Affinity DataKi:  8.90nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM335704((R)-3-(3-Methyl-2-oxopyrrolidin-3-yl)-6-(5-methylq...)
Affinity DataKi:  18.6nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM335703((R)-3-(6-(5-fluoroquinolin-7-yl)-2-hydroxypyridin-...)
Affinity DataKi:  48.6nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent