Compile Data Set for Download or QSAR
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Found 20 Enz. Inhib. hit(s) with all data for entry = 1690
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141376(US8916600, 10 | US9738632, Example 10)
Affinity DataIC50:  0.647nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141385(US8916600, 19 | US9738632, Example 19)
Affinity DataIC50:  0.663nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141378(US8916600, 12 | US9738632, Example 12)
Affinity DataIC50:  0.767nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141373(US8916600, 7 | US9738632, Example 8)
Affinity DataIC50:  0.796nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141379(US8916600, 13 | US9738632, Example 13)
Affinity DataIC50:  0.817nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141372(US8916600, 6 | US9738632, Example 6)
Affinity DataIC50:  0.913nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141383(US8916600, 17 | US9738632, Example 17)
Affinity DataIC50:  0.996nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141371(US8916600, 5 | US9738632, Example 5)
Affinity DataIC50:  1.08nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141375(US8916600, 9 | US9738632, Example 9)
Affinity DataIC50:  1.09nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141373(US8916600, 7 | US9738632, Example 8)
Affinity DataIC50:  1.30nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141367(US8916600, 1 | US8916600, 4 | US9738632, Example 1)
Affinity DataIC50:  1.32nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141368(US8916600, 2 | US8916600, 3 | US9738632, Example 2)
Affinity DataIC50:  1.36nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM335727(US9738632, Example 4)
Affinity DataIC50:  1.40nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM335726(US9738632, Example 3)
Affinity DataIC50:  1.60nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141380(US8916600, 14 | US9738632, Example 14)
Affinity DataIC50:  1.75nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141386(US8916600, 20 | US9738632, Example 20)
Affinity DataIC50:  1.96nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141377(US8916600, 11 | US9738632, Example 11)
Affinity DataIC50:  2.15nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141384(US8916600, 18 | US9738632, Example 18)
Affinity DataIC50:  3.44nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141381(US8916600, 15 | US8916600, 16 | US9738632, Example...)
Affinity DataIC50:  3.64nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141381(US8916600, 15 | US8916600, 16 | US9738632, Example...)
Affinity DataIC50:  4.27nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In DepthDetails US Patent