Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 3442
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM400643(N-[3-[(4aR,7aS)-2-Amino-6-(5-fluoropyrimidin-2-yl)...)
Affinity DataIC50:  0.358nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM400607(US9999624, 6)
Affinity DataIC50:  0.450nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM400331(US9999624, 2)
Affinity DataIC50:  0.482nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150688(US8987254, 3 | US9999624, 3)
Affinity DataIC50:  0.603nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150686(US8987254, 1 | US9999624, 1)
Affinity DataIC50:  0.610nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM400979(US9999624, Compound 4)
Affinity DataIC50:  0.615nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150691(US8987254, 6 | US9999624, 7)
Affinity DataIC50:  0.739nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)
Affinity DataIC50:  0.780nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent