Compile Data Set for Download or QSAR

Found 28 hits Enz. Inhib. hit(s) with all data for entry = 8718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380039 (5-[3-(Cyanomethyl)-3-(3′-methyl-1H,1′H...) Show SMILES C[C@H](NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1cn[nH]c1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM246853 (4-[3-(cyanomethyl)- 3-(3',5'-dimethyl- 1H,...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1c(C)n[nH]c1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380444 (5-[3-(Cyanomethyl)-3-(3′,5′-dimethyl-1...) Show SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1c(C)n[nH]c1C Show InChI InChI=1S/C21H25N9O/c1-13(2)26-20(31)17-8-24-18(9-23-17)29-11-21(12-29,5-6-22)30-10-16(7-25-30)19-14(3)27-28-15(19)4/h7-10,13H,5,11-12H2,1-4H3,(H,26,31)(H,27,28)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380442 (5-[3-(Cyanomethyl)-3-(3,3′-dimethyl-1H,1R...) Show SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(c(C)n1)-c1c[nH]nc1C Show InChI InChI=1S/C21H25N9O/c1-13(2)26-20(31)18-8-24-19(9-23-18)29-11-21(12-29,5-6-22)30-10-17(15(4)28-30)16-7-25-27-14(16)3/h7-10,13H,5,11-12H2,1-4H3,(H,25,27)(H,26,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380445 (5-[3-(Cyanomethyl)-3-(3′,5′-dimethyl-1...) Show SMILES C[C@H](NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1c(C)n[nH]c1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380449 (4-{3-(Cyanomethyl)-3-[3-(hydroxymethyl)-3′-m...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(c(CO)n1)-c1c[nH]nc1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380426 (4-[3-(Cyanomethyl)-3-(3′-methyl-1H,1′H...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]nc1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM246853 (4-[3-(cyanomethyl)- 3-(3',5'-dimethyl- 1H,...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1c(C)n[nH]c1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380063 (5-[3-(Cyanomethyl)-3-(3′-methyl-1H,1′H...) Show SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]nc1C Show InChI InChI=1S/C20H23N9O/c1-13(2)26-19(30)17-8-23-18(9-22-17)28-11-20(12-28,4-5-21)29-10-15(6-25-29)16-7-24-27-14(16)3/h6-10,13H,4,11-12H2,1-3H3,(H,24,27)(H,26,30)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380422 (4-[3-(Cyanomethyl)-3-(3′-methyl-1H,1′H...) Show SMILES CC(C)NC(=O)c1ccc(cc1)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]nc1C Show InChI InChI=1S/C22H25N7O/c1-15(2)26-21(30)17-4-6-19(7-5-17)28-13-22(14-28,8-9-23)29-12-18(10-25-29)20-11-24-27-16(20)3/h4-7,10-12,15H,8,13-14H2,1-3H3,(H,24,27)(H,26,30)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM246853 (4-[3-(cyanomethyl)- 3-(3',5'-dimethyl- 1H,...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1c(C)n[nH]c1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380441 (4-[3-(1H,1′H-4,4′-Bipyrazol-1-yl)-3-(c...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1cn[nH]c1)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380426 (4-[3-(Cyanomethyl)-3-(3′-methyl-1H,1′H...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]nc1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380063 (5-[3-(Cyanomethyl)-3-(3′-methyl-1H,1′H...) Show SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]nc1C Show InChI InChI=1S/C20H23N9O/c1-13(2)26-19(30)17-8-23-18(9-22-17)28-11-20(12-28,4-5-21)29-10-15(6-25-29)16-7-24-27-14(16)3/h6-10,13H,4,11-12H2,1-3H3,(H,24,27)(H,26,30)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM246853 (4-[3-(cyanomethyl)- 3-(3',5'-dimethyl- 1H,...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1c(C)n[nH]c1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380448 (4-{3-(Cyanomethyl)-3-[3′-(hydroxymethyl)-1H,...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]nc1CO)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380447 (5-[3-(Cyanomethyl)-3-(3′-ethyl-1H,1′H-...) Show SMILES CCc1n[nH]cc1-c1cnn(c1)C1(CC#N)CN(C1)c1cnc(cn1)C(=O)N[C@@H](C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Homo sapiens (Human))	BDBM380446 (5-[3-(Cyanomethyl)-3-(3-methyl-1H,1′H-4,4...) Show SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(c(C)n1)-c1cn[nH]c1 Show InChI InChI=1S/C20H23N9O/c1-13(2)26-19(30)17-8-23-18(9-22-17)28-11-20(12-28,4-5-21)29-10-16(14(3)27-29)15-6-24-25-7-15/h6-10,13H,4,11-12H2,1-3H3,(H,24,25)(H,26,30)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380445 (5-[3-(Cyanomethyl)-3-(3′,5′-dimethyl-1...) Show SMILES C[C@H](NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1c(C)n[nH]c1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380444 (5-[3-(Cyanomethyl)-3-(3′,5′-dimethyl-1...) Show SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1c(C)n[nH]c1C Show InChI InChI=1S/C21H25N9O/c1-13(2)26-20(31)17-8-24-18(9-23-17)29-11-21(12-29,5-6-22)30-10-16(7-25-30)19-14(3)27-28-15(19)4/h7-10,13H,5,11-12H2,1-4H3,(H,26,31)(H,27,28)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380039 (5-[3-(Cyanomethyl)-3-(3′-methyl-1H,1′H...) Show SMILES C[C@H](NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(cn1)-c1cn[nH]c1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>700	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380449 (4-{3-(Cyanomethyl)-3-[3-(hydroxymethyl)-3′-m...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(c(CO)n1)-c1c[nH]nc1C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380447 (5-[3-(Cyanomethyl)-3-(3′-ethyl-1H,1′H-...) Show SMILES CCc1n[nH]cc1-c1cnn(c1)C1(CC#N)CN(C1)c1cnc(cn1)C(=O)N[C@@H](C)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380446 (5-[3-(Cyanomethyl)-3-(3-methyl-1H,1′H-4,4...) Show SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(c(C)n1)-c1cn[nH]c1 Show InChI InChI=1S/C20H23N9O/c1-13(2)26-19(30)17-8-23-18(9-22-17)28-11-20(12-28,4-5-21)29-10-16(14(3)27-29)15-6-24-25-7-15/h6-10,13H,4,11-12H2,1-3H3,(H,24,25)(H,26,30)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380422 (4-[3-(Cyanomethyl)-3-(3′-methyl-1H,1′H...) Show SMILES CC(C)NC(=O)c1ccc(cc1)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]nc1C Show InChI InChI=1S/C22H25N7O/c1-15(2)26-21(30)17-4-6-19(7-5-17)28-13-22(14-28,8-9-23)29-12-18(10-25-29)20-11-24-27-16(20)3/h4-7,10-12,15H,8,13-14H2,1-3H3,(H,24,27)(H,26,30)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380448 (4-{3-(Cyanomethyl)-3-[3′-(hydroxymethyl)-1H,...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]nc1CO)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380441 (4-[3-(1H,1′H-4,4′-Bipyrazol-1-yl)-3-(c...) Show SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)n1cc(cn1)-c1cn[nH]c1)C(F)(F)F Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human))	BDBM380442 (5-[3-(Cyanomethyl)-3-(3,3′-dimethyl-1H,1R...) Show SMILES CC(C)NC(=O)c1cnc(cn1)N1CC(CC#N)(C1)n1cc(c(C)n1)-c1c[nH]nc1C Show InChI InChI=1S/C21H25N9O/c1-13(2)26-20(31)18-8-24-19(9-23-18)29-11-21(12-29,5-6-22)30-10-17(15(4)28-30)16-7-25-27-14(16)3/h7-10,13H,5,11-12H2,1-4H3,(H,25,27)(H,26,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...				US Patent US10435392 (2019) BindingDB Entry DOI: 10.7270/Q2D50QB7
					More data for this Ligand-Target Pair