Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304059 (4-{2-benzyl-5-(4-methylphenyl)-3-oxo-8-[(3R)-pyrro...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(Cc3ccccc3)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C32H29N5O2/c1-22-7-11-27(12-8-22)30-28(26-13-9-23(18-33)10-14-26)17-29(39-21-25-15-16-34-19-25)31-35-36(32(38)37(30)31)20-24-5-3-2-4-6-24/h2-14,17,25,34H,15-16,19-21H2,1H3/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304058 (4-{2-[2-(dimethylamino)ethyl]-5-(4-methylphenyl)-3...) Show SMILES CN(C)CCn1nc2c(OC[C@@H]3CCNC3)cc(-c3ccc(cc3)C#N)c(-c3ccc(C)cc3)n2c1=O Show InChI InChI=1S/C29H32N6O2/c1-20-4-8-24(9-5-20)27-25(23-10-6-21(17-30)7-11-23)16-26(37-19-22-12-13-31-18-22)28-32-34(15-14-33(2)3)29(36)35(27)28/h4-11,16,22,31H,12-15,18-19H2,1-3H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304057 (4-{5-(4-methylphenyl)-3-oxo-2-(2-phenoxyethyl)-8-[...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CCOc3ccccc3)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C33H31N5O3/c1-23-7-11-27(12-8-23)31-29(26-13-9-24(20-34)10-14-26)19-30(41-22-25-15-16-35-21-25)32-36-37(33(39)38(31)32)17-18-40-28-5-3-2-4-6-28/h2-14,19,25,35H,15-18,21-22H2,1H3/t25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304056 (4-{5-(4-methylphenyl)-3-oxo-2-(piperidin-4-ylmethy...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CC3CCNCC3)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C31H34N6O2/c1-21-2-6-26(7-3-21)29-27(25-8-4-22(17-32)5-9-25)16-28(39-20-24-12-15-34-18-24)30-35-36(31(38)37(29)30)19-23-10-13-33-14-11-23/h2-9,16,23-24,33-34H,10-15,18-20H2,1H3/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304048 ((R)-4-(2-(cyanomethyl)-3-oxo-8-(pyrrolidin-3-ylmet...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CC#N)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H24N6O2/c1-18-2-6-22(7-3-18)25-23(21-8-4-19(15-29)5-9-21)14-24(35-17-20-10-12-30-16-20)26-31-32(13-11-28)27(34)33(25)26/h2-9,14,20,30H,10,12-13,16-17H2,1H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304060 (4-{2-(4-cyanobenzyl)-5-(4-methylphenyl)-3-oxo-8-[(...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(Cc3ccc(cc3)C#N)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C33H28N6O2/c1-22-2-10-28(11-3-22)31-29(27-12-8-24(18-35)9-13-27)16-30(41-21-26-14-15-36-19-26)32-37-38(33(40)39(31)32)20-25-6-4-23(17-34)5-7-25/h2-13,16,26,36H,14-15,19-21H2,1H3/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304050 (4-{2-(cyclopentylmethyl)-5-(4-methylphenyl)-3-oxo-...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CC3CCCC3)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C31H33N5O2/c1-21-6-10-26(11-7-21)29-27(25-12-8-22(17-32)9-13-25)16-28(38-20-24-14-15-33-18-24)30-34-35(31(37)36(29)30)19-23-4-2-3-5-23/h6-13,16,23-24,33H,2-5,14-15,18-20H2,1H3/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304044 (4-{5-(4-methylphenyl)-8-[(3R)-pyrrolidin-3-ylmetho...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C25H23N5O/c1-17-2-6-21(7-3-17)24-22(20-8-4-18(13-26)5-9-20)12-23(25-29-28-16-30(24)25)31-15-19-10-11-27-14-19/h2-9,12,16,19,27H,10-11,14-15H2,1H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304045 (2-fluoro-4-{5-(4-methylphenyl)-8-[(3R)-pyrrolidin-...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nncn12)-c1ccc(C#N)c(F)c1 Show InChI InChI=1S/C25H22FN5O/c1-16-2-4-18(5-3-16)24-21(19-6-7-20(12-27)22(26)10-19)11-23(25-30-29-15-31(24)25)32-14-17-8-9-28-13-17/h2-7,10-11,15,17,28H,8-9,13-14H2,1H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304046 (4-{5-(4-methylphenyl)-3-oxo-8-[(3R)-pyrrolidin-3-y...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2n[nH]c(=O)n12)-c1ccc(cc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304049 (4-{2-(2-cyanoethyl)-5-(4-methylphenyl)-3-oxo-8-[(3...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CCC#N)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C28H26N6O2/c1-19-3-7-23(8-4-19)26-24(22-9-5-20(16-30)6-10-22)15-25(36-18-21-11-13-31-17-21)27-32-33(14-2-12-29)28(35)34(26)27/h3-10,15,21,31H,2,11,13-14,17-18H2,1H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304055 (4-[5-(4-methylphenyl)-3-oxo-8-[(3R)-pyrrolidin-3-y...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CC(O)C(F)(F)F)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C28H26F3N5O3/c1-17-2-6-21(7-3-17)25-22(20-8-4-18(13-32)5-9-20)12-23(39-16-19-10-11-33-14-19)26-34-35(27(38)36(25)26)15-24(37)28(29,30)31/h2-9,12,19,24,33,37H,10-11,14-16H2,1H3/t19-,24?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304054 (2-[6-(4-cyanophenyl)-5-(4-methylphenyl)-3-oxo-8-[(...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CC(N)=O)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H26N6O3/c1-17-2-6-21(7-3-17)25-22(20-8-4-18(13-28)5-9-20)12-23(36-16-19-10-11-30-14-19)26-31-32(15-24(29)34)27(35)33(25)26/h2-9,12,19,30H,10-11,14-16H2,1H3,(H2,29,34)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304063 (4-{5-(4-methylphenyl)-3-oxo-8-[(3R)-pyrrolidin-3-y...) Show SMILES Cc1ccc(cc1)-c1c(nc(OC[C@@H]2CCNC2)c2n[nH]c(=O)n12)-c1ccc(cc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304052 (4-{5-(4-methylphenyl)-2-[(1-methyl-1H-pyrazol-3-yl...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(Cc3ccn(C)n3)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C30H29N7O2/c1-20-3-7-24(8-4-20)28-26(23-9-5-21(16-31)6-10-23)15-27(39-19-22-11-13-32-17-22)29-34-36(30(38)37(28)29)18-25-12-14-35(2)33-25/h3-10,12,14-15,22,32H,11,13,17-19H2,1-2H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304051 (4-[5-(4-methylphenyl)-3-oxo-8-[(3R)-pyrrolidin-3-y...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CC3CCCO3)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C30H31N5O3/c1-20-4-8-24(9-5-20)28-26(23-10-6-21(16-31)7-11-23)15-27(38-19-22-12-13-32-17-22)29-33-34(30(36)35(28)29)18-25-3-2-14-37-25/h4-11,15,22,25,32H,2-3,12-14,17-19H2,1H3/t22-,25?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304053 (4-{5-(4-methylphenyl)-2-(2-morpholin-4-ylethyl)-3-...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CCN3CCOCC3)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C31H34N6O3/c1-22-2-6-26(7-3-22)29-27(25-8-4-23(19-32)5-9-25)18-28(40-21-24-10-11-33-20-24)30-34-36(31(38)37(29)30)13-12-35-14-16-39-17-15-35/h2-9,18,24,33H,10-17,20-21H2,1H3/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304061 (4-{2-(2-hydroxyethyl)-5-(4-methylphenyl)-3-oxo-8-[...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(CCO)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H27N5O3/c1-18-2-6-22(7-3-18)25-23(21-8-4-19(15-28)5-9-21)14-24(35-17-20-10-11-29-16-20)26-30-31(12-13-33)27(34)32(25)26/h2-9,14,20,29,33H,10-13,16-17H2,1H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304062 (4-{5-(4-methylphenyl)-8-[(3R)-pyrrolidin-3-ylmetho...) Show SMILES Cc1ccc(cc1)-c1c(nc(OC[C@@H]2CCNC2)c2nncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C24H22N6O/c1-16-2-6-20(7-3-16)22-21(19-8-4-17(12-25)5-9-19)28-24(23-29-27-15-30(22)23)31-14-18-10-11-26-13-18/h2-9,15,18,26H,10-11,13-14H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM304047 (4-{2-methyl-5-(4-methylphenyl)-3-oxo-8-[(3R)-pyrro...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2nn(C)c(=O)n12)-c1ccc(cc1)C#N Show InChI InChI=1S/C26H25N5O2/c1-17-3-7-21(8-4-17)24-22(20-9-5-18(14-27)6-10-20)13-23(33-16-19-11-12-28-15-19)25-29-30(2)26(32)31(24)25/h3-10,13,19,28H,11-12,15-16H2,1-2H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10138249 (2018) BindingDB Entry DOI: 10.7270/Q2GB2630
					More data for this Ligand-Target Pair