Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1132
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310889(4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N...)
Affinity DataIC50:  51nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310880(7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4...)
Affinity DataIC50:  58nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310879(2-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-5...)
Affinity DataIC50:  81nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310884(4-[4-(3-fluoroazetidine-1-carbonyl)phenyl]-6-methy...)
Affinity DataIC50:  84nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310874(US10150767, Example 4 | tert-butyl 6-(6-methyl-7-o...)
Affinity DataIC50:  110nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310876(3-methyl-6-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)
Affinity DataIC50:  110nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310878(3-isopropyl-6-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyr...)
Affinity DataIC50:  110nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310882(3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)be...)
Affinity DataIC50:  150nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310886(6-methyl-4-[4-(4-methylpiperidine-1-carbonyl)pheny...)
Affinity DataIC50:  170nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310877(4-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)
Affinity DataIC50:  170nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310881(3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)be...)
Affinity DataIC50:  180nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310891(N-(cyanomethyl)-N-methyl-4-(6-methyl-7-oxo-1H-pyrr...)
Affinity DataIC50:  200nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310873(6-methyl-4-(2-oxoindolin-5-yl)-1H-pyrrolo[2,3-c]py...)
Affinity DataIC50:  210nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310886(6-methyl-4-[4-(4-methylpiperidine-1-carbonyl)pheny...)
Affinity DataIC50:  260nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310885(6-methyl-4-[4-(pyrrolidine-1-carbonyl)phenyl]-1H-p...)
Affinity DataIC50:  280nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310875(8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyr...)
Affinity DataIC50:  310nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310887(4-[4-(4-acetylpiperazine-1-carbonyl)phenyl]-6-meth...)
Affinity DataIC50:  320nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310890(N-methyl-4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)
Affinity DataIC50:  340nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310872(6-methyl-4-phenyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-o...)
Affinity DataIC50:  540nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310883(4-[4-(hydroxymethyl)phenyl]-6-methyl-1H-pyrrolo[2,...)
Affinity DataIC50:  710nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent