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Found 11 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2852
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25314(2-[(5,6-diphenyl-1,2,4-triazin-3-yl)sulfanyl]-N-(1...)
Affinity DataIC50:  4.00E+3nMpH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25322(2-bromo-3,5-dinitro-N-[(phenylcarbamoyl)amino]benz...)
Affinity DataIC50:  5.50E+3nMpH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25316(ChemBridge nitrobenzothiazole, 6 | N-(6-nitro-1,3-...)
Affinity DataIC50:  6.00E+3nMpH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25318((4-methoxyphenyl)methyl 2-methyl-5-oxo-4,7-bis(thi...)
Affinity DataIC50:  1.00E+4nMpH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25317(3-hydroxy-4-[(E)-2-(1-hydroxynaphthalen-2-yl)diaze...)
Affinity DataIC50:  1.00E+4nMpH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25323(2-({7-[(3-hydroxyphenyl)amino]-4-nitro-2,1,3-benzo...)
Affinity DataIC50:  1.19E+4nMpH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25324(ChemBridge nitrobenzothiazole, 19 | ethyl 0-[(6-ni...)
Affinity DataIC50:  1.39E+4nMpH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25321((4E)-4-[(4-chlorophenyl)(hydroxy)methylidene]-1-(p...)
Affinity DatapH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25325(2-[methyl(6-nitro-1,3-benzothiazol-2-yl)amino]acet...)
Affinity DatapH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25319(4,6-bis(benzylsulfanyl)pyrimidine-2,5-diamine | Ch...)
Affinity DatapH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP phosphoribosyltransferase(Mycobacterium tuberculosis)
Yale University

LigandPNGBDBM25320(4-[(E)-2-{2,6-diamino-3-methyl-5-[(E)-2-(4-sulfoph...)
Affinity DatapH: 8.5 T: 2°CAssay Description:Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed