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Compile Data Set for Download or QSAR

Found 69 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 6102   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108297
PNG
(US8604046, 77)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(cc1)N1CCC2(CCN(CC2)C(=O)OC(C)(C)C)C1=O
Show InChI InChI=1/C29H44N4O3/c1-22-6-5-16-32(22)25-11-17-30(18-12-25)23-7-9-24(10-8-23)33-21-15-29(26(33)34)13-19-31(20-14-29)27(35)36-28(2,3)4/h7-10,22,25H,5-6,11-21H2,1-4H3/t22-/s2
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0.00800n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108281
PNG
(US8604046, 61)
Show SMILES CC(C)(C)OC(=O)N1CCC2(CCCN(C2=O)c2ccc(cc2F)N2CC[C@@H](C2)N2CCCC2)CC1
Show InChI InChI=1/C28H41FN4O3/c1-27(2,3)36-26(35)31-17-11-28(12-18-31)10-6-15-33(25(28)34)24-8-7-21(19-23(24)29)32-16-9-22(20-32)30-13-4-5-14-30/h7-8,19,22H,4-6,9-18,20H2,1-3H3/t22-/s2
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0.0300n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108294
PNG
(US8604046, 74)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCCC2(CCN(CC2)C2CCOCC2)C1=O
Show InChI InChI=1/C29H44N4O2/c1-23-4-2-15-32(23)27-9-17-31(22-27)24-5-7-26(8-6-24)33-16-3-12-29(28(33)34)13-18-30(19-14-29)25-10-20-35-21-11-25/h5-8,23,25,27H,2-4,9-22H2,1H3/t23-,27-/s2
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0.0400n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108315
PNG
(US8604046, 95)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCN(CC4CC4)CC3)C2=O)c(F)c1
Show InChI InChI=1/C28H41FN4O/c1-21-3-2-13-32(21)23-8-14-31(15-9-23)24-6-7-26(25(29)19-24)33-18-12-28(27(33)34)10-16-30(17-11-28)20-22-4-5-22/h6-7,19,21-23H,2-5,8-18,20H2,1H3/t21-/s2
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0.0400n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108295
PNG
(US8604046, 75)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(Cc4ccccc4)CC3)C2=O)c(F)c1
Show InChI InChI=1/C31H41FN4O/c1-24-7-5-16-35(24)27-12-18-34(23-27)26-10-11-29(28(32)21-26)36-17-6-13-31(30(36)37)14-19-33(20-15-31)22-25-8-3-2-4-9-25/h2-4,8-11,21,24,27H,5-7,12-20,22-23H2,1H3/t24-,27-/s2
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0.0600n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108284
PNG
(US8604046, 64)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCNCC3)C2=O)c(F)c1
Show InChI InChI=1/C24H35FN4O/c1-18-4-2-13-28(18)20-7-15-27(17-20)19-5-6-22(21(25)16-19)29-14-3-8-24(23(29)30)9-11-26-12-10-24/h5-6,16,18,20,26H,2-4,7-15,17H2,1H3/t18-,20-/s2
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US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108282
PNG
(US8604046, 62)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCNCC3)C2=O)c(C)c1
Show InChI InChI=1/C25H38N4O/c1-19-17-21(27-16-8-22(18-27)28-14-3-5-20(28)2)6-7-23(19)29-15-4-9-25(24(29)30)10-12-26-13-11-25/h6-7,17,20,22,26H,3-5,8-16,18H2,1-2H3/t20-,22-/s2
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0.0700n/an/an/an/an/an/an/an/a



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US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108310
PNG
(US8604046, 90)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(cc1)N1CCC2(CCN(CC2)C(=O)c2ccc(F)cc2)C1=O
Show InChI InChI=1/C31H39FN4O2/c1-23-3-2-17-35(23)28-12-18-33(19-13-28)26-8-10-27(11-9-26)36-22-16-31(30(36)38)14-20-34(21-15-31)29(37)24-4-6-25(32)7-5-24/h4-11,23,28H,2-3,12-22H2,1H3/t23-/s2
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0.0800n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108328
PNG
(US8604046, 108)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCNCC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C24H33F3N4O/c1-17-3-2-12-30(17)19-6-13-29(16-19)18-4-5-21(20(15-18)24(25,26)27)31-14-9-23(22(31)32)7-10-28-11-8-23/h4-5,15,17,19,28H,2-3,6-14,16H2,1H3/t17-,19-/s2
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0.0900n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108303
PNG
(US8604046, 83)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(cc1)N1CCC2(CCNCC2)C1=O
Show InChI InChI=1/C24H36N4O/c1-19-3-2-15-27(19)22-8-16-26(17-9-22)20-4-6-21(7-5-20)28-18-12-24(23(28)29)10-13-25-14-11-24/h4-7,19,22,25H,2-3,8-18H2,1H3/t19-/s2
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0.100n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108316
PNG
(US8604046, 96)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCN(CC4CCCC4)CC3)C2=O)c(F)c1
Show InChI InChI=1/C30H45FN4O/c1-23-5-4-15-34(23)25-10-16-33(17-11-25)26-8-9-28(27(31)21-26)35-20-14-30(29(35)36)12-18-32(19-13-30)22-24-6-2-3-7-24/h8-9,21,23-25H,2-7,10-20,22H2,1H3/t23-/s2
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0.100n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108305
PNG
(US8604046, 85)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCNCC3)C2=O)c(F)c1
Show InChI InChI=1/C24H35FN4O/c1-18-3-2-13-28(18)19-6-14-27(15-7-19)20-4-5-22(21(25)17-20)29-16-10-24(23(29)30)8-11-26-12-9-24/h4-5,17-19,26H,2-3,6-16H2,1H3/t18-/s2
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0.100n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108296
PNG
(US8604046, 76)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(Cc4ccco4)CC3)C2=O)c(F)c1
Show InChI InChI=1/C29H39FN4O2/c1-22-5-2-13-33(22)24-9-15-32(20-24)23-7-8-27(26(30)19-23)34-14-4-10-29(28(34)35)11-16-31(17-12-29)21-25-6-3-18-36-25/h3,6-8,18-19,22,24H,2,4-5,9-17,20-21H2,1H3/t22-,24-/s2
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0.100n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108283
PNG
(US8604046, 63)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCCC2(CCNCC2)C1=O
Show InChI InChI=1/C24H36N4O/c1-19-4-2-15-27(19)22-9-17-26(18-22)20-5-7-21(8-6-20)28-16-3-10-24(23(28)29)11-13-25-14-12-24/h5-8,19,22,25H,2-4,9-18H2,1H3/t19-,22-/s2
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0.100n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108317
PNG
(US8604046, 97)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC4CCCCC4)CC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C32H47F3N4O/c1-24-7-5-6-16-38(24)27-12-17-37(23-27)26-10-11-29(28(21-26)32(33,34)35)39-20-15-31(30(39)40)13-18-36(19-14-31)22-25-8-3-2-4-9-25/h10-11,21,24-25,27H,2-9,12-20,22-23H2,1H3/t24-,27-/s2
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0.150n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108304
PNG
(US8604046, 84)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCNCC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C25H35F3N4O/c1-18-3-2-13-31(18)19-6-14-30(15-7-19)20-4-5-22(21(17-20)25(26,27)28)32-16-10-24(23(32)33)8-11-29-12-9-24/h4-5,17-19,29H,2-3,6-16H2,1H3/t18-/s2
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US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108293
PNG
(US8604046, 73)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCCC2(CCN(CC3CC3)CC2)C1=O
Show InChI InChI=1/C28H42N4O/c1-22-4-2-15-31(22)26-11-17-30(21-26)24-7-9-25(10-8-24)32-16-3-12-28(27(32)33)13-18-29(19-14-28)20-23-5-6-23/h7-10,22-23,26H,2-6,11-21H2,1H3/t22-,26-/s2
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Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108311
PNG
(US8604046, 91)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCN(CC3)C(=O)C3CCCCC3)C2=O)c(F)c1
Show InChI InChI=1/C31H45FN4O2/c1-23-6-5-16-35(23)25-11-17-33(18-12-25)26-9-10-28(27(32)22-26)36-21-15-31(30(36)38)13-19-34(20-14-31)29(37)24-7-3-2-4-8-24/h9-10,22-25H,2-8,11-21H2,1H3/t23-/s2
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0.200n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108292
PNG
(US8604046, 72)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(CC4CCCCC4)CC3)C2=O)c(C)c1
Show InChI InChI=1/C32H50N4O/c1-25-22-28(34-19-13-29(24-34)35-17-6-8-26(35)2)11-12-30(25)36-18-7-14-32(31(36)37)15-20-33(21-16-32)23-27-9-4-3-5-10-27/h11-12,22,26-27,29H,3-10,13-21,23-24H2,1-2H3/t26-,29-/s2
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0.200n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108309
PNG
(US8604046, 89)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(cc1)N1CCC2(CCN(CC2)S(=O)(=O)c2ccccc2)C1=O
Show InChI InChI=1/C30H40N4O3S/c1-24-6-5-18-33(24)27-13-19-31(20-14-27)25-9-11-26(12-10-25)34-23-17-30(29(34)35)15-21-32(22-16-30)38(36,37)28-7-3-2-4-8-28/h2-4,7-12,24,27H,5-6,13-23H2,1H3/t24-/s2
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0.240n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108299
PNG
(US8604046, 79)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCN(CC3)C(=O)OC(C)(C)C)C2=O)c(F)c1
Show InChI InChI=1/C29H43FN4O3/c1-21-6-5-14-33(21)22-9-15-31(16-10-22)23-7-8-25(24(30)20-23)34-19-13-29(26(34)35)11-17-32(18-12-29)27(36)37-28(2,3)4/h7-8,20-22H,5-6,9-19H2,1-4H3/t21-/s2
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0.300n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108306
PNG
(US8604046, 86)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCC2(CCNCC2)C1=O
Show InChI InChI=1/C24H36N4O/c1-19-4-2-3-15-27(19)22-9-16-26(18-22)20-5-7-21(8-6-20)28-17-12-24(23(28)29)10-13-25-14-11-24/h5-8,19,22,25H,2-4,9-18H2,1H3/t19-,22-/s2
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0.400n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108288
PNG
(US8604046, 68)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCCC2(CCN(CC2)C(=O)c2ccc(F)cc2)C1=O
Show InChI InChI=1/C31H39FN4O2/c1-23-4-2-17-35(23)28-13-19-34(22-28)26-9-11-27(12-10-26)36-18-3-14-31(30(36)38)15-20-33(21-16-31)29(37)24-5-7-25(32)8-6-24/h5-12,23,28H,2-4,13-22H2,1H3/t23-,28-/s2
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0.400n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108290
PNG
(US8604046, 70)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(CC3)C(=O)C3CCOCC3)C2=O)c(F)c1
Show InChI InChI=1/C30H43FN4O3/c1-22-4-2-13-34(22)25-7-15-33(21-25)24-5-6-27(26(31)20-24)35-14-3-10-30(29(35)37)11-16-32(17-12-30)28(36)23-8-18-38-19-9-23/h5-6,20,22-23,25H,2-4,7-19,21H2,1H3/t22-,25-/s2
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0.400n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108291
PNG
(US8604046, 71)
Show SMILES CC(C)N1CCC2(CCCN(C2=O)c2ccc(cc2C)N2CC[C@@H](C2)N2CCC[C@@H]2C)CC1
Show InChI InChI=1/C28H44N4O/c1-21(2)29-17-12-28(13-18-29)11-6-15-32(27(28)33)26-9-8-24(19-22(26)3)30-16-10-25(20-30)31-14-5-7-23(31)4/h8-9,19,21,23,25H,5-7,10-18,20H2,1-4H3/t23-,25-/s2
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0.400n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108287
PNG
(US8604046, 67)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCCC2(CCN(CC2)C(=O)c2ccccc2)C1=O
Show InChI InChI=1/C31H40N4O2/c1-24-7-5-18-34(24)28-14-20-33(23-28)26-10-12-27(13-11-26)35-19-6-15-31(30(35)37)16-21-32(22-17-31)29(36)25-8-3-2-4-9-25/h2-4,8-13,24,28H,5-7,14-23H2,1H3/t24-,28-/s2
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0.5n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108308
PNG
(US8604046, 88)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCNCC3)C2=O)c(F)c1
Show InChI InChI=1/C24H35FN4O/c1-18-4-2-3-13-28(18)20-7-14-27(17-20)19-5-6-22(21(25)16-19)29-15-10-24(23(29)30)8-11-26-12-9-24/h5-6,16,18,20,26H,2-4,7-15,17H2,1H3/t18-,20-/s2
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0.5n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108307
PNG
(US8604046, 87)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCNCC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C25H35F3N4O/c1-18-4-2-3-13-31(18)20-7-14-30(17-20)19-5-6-22(21(16-19)25(26,27)28)32-15-10-24(23(32)33)8-11-29-12-9-24/h5-6,16,18,20,29H,2-4,7-15,17H2,1H3/t18-,20-/s2
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0.600n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108268
PNG
(US8604046, 48)
Show SMILES C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(N2CCC3(CCNCC3)C2=O)c(C)c1
Show InChI InChI=1/C24H36N4O/c1-18-16-20(26-14-7-21(17-26)27-13-3-4-19(27)2)5-6-22(18)28-15-10-24(23(28)29)8-11-25-12-9-24/h5-6,16,19,21,25H,3-4,7-15,17H2,1-2H3/t19-,21+/s2
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0.600n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108289
PNG
(US8604046, 69)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(CC3)C(=O)C3CCCCC3)C2=O)c(F)c1
Show InChI InChI=1/C31H45FN4O2/c1-23-7-5-16-35(23)26-12-18-34(22-26)25-10-11-28(27(32)21-25)36-17-6-13-31(30(36)38)14-19-33(20-15-31)29(37)24-8-3-2-4-9-24/h10-11,21,23-24,26H,2-9,12-20,22H2,1H3/t23-,26-/s2
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0.700n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108271
PNG
(US8604046, 51)
Show SMILES C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC4CCCC4)CC3)C2=O)c(C)c1
Show InChI InChI=1/C30H46N4O/c1-23-20-26(32-16-11-27(22-32)33-15-5-6-24(33)2)9-10-28(23)34-19-14-30(29(34)35)12-17-31(18-13-30)21-25-7-3-4-8-25/h9-10,20,24-25,27H,3-8,11-19,21-22H2,1-2H3/t24-,27+/s2
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0.800n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108272
PNG
(US8604046, 52)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC4CCCC4)CC3)C2=O)c(C)c1
Show InChI InChI=1/C30H46N4O/c1-23-20-26(32-16-11-27(22-32)33-15-5-6-24(33)2)9-10-28(23)34-19-14-30(29(34)35)12-17-31(18-13-30)21-25-7-3-4-8-25/h9-10,20,24-25,27H,3-8,11-19,21-22H2,1-2H3/t24-,27-/s2
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0.800n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108267
PNG
(US8604046, 47)
Show SMILES C[C@@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCNCC3)C2=O)c(C)c1
Show InChI InChI=1/C24H36N4O/c1-18-16-20(26-14-7-21(17-26)27-13-3-4-19(27)2)5-6-22(18)28-15-10-24(23(28)29)8-11-25-12-9-24/h5-6,16,19,21,25H,3-4,7-15,17H2,1-2H3/t19-,21+/s2
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0.800n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108298
PNG
(US8604046, 78)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCN(CC3)C(=O)OC(C)(C)C)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C30H43F3N4O3/c1-21-6-5-14-36(21)22-9-15-34(16-10-22)23-7-8-25(24(20-23)30(31,32)33)37-19-13-29(26(37)38)11-17-35(18-12-29)27(39)40-28(2,3)4/h7-8,20-22H,5-6,9-19H2,1-4H3/t21-/s2
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0.900n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108278
PNG
(US8604046, 58)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC3)C(=O)c3ccc(OC(F)(F)F)cc3)C2=O)c(C)c1
Show InChI InChI=1/C32H39F3N4O3/c1-22-20-25(37-16-11-26(21-37)38-15-3-4-23(38)2)7-10-28(22)39-19-14-31(30(39)41)12-17-36(18-13-31)29(40)24-5-8-27(9-6-24)42-32(33,34)35/h5-10,20,23,26H,3-4,11-19,21H2,1-2H3/t23-,26-/s2
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1.40n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108276
PNG
(US8604046, 56)
Show SMILES C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC3)C(=O)c3ccc(OC(F)(F)F)cc3)C2=O)c(C)c1
Show InChI InChI=1/C32H39F3N4O3/c1-22-20-25(37-16-11-26(21-37)38-15-3-4-23(38)2)7-10-28(22)39-19-14-31(30(39)41)12-17-36(18-13-31)29(40)24-5-8-27(9-6-24)42-32(33,34)35/h5-10,20,23,26H,3-4,11-19,21H2,1-2H3/t23-,26+/s2
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1.40n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108326
PNG
(US8604046, 106)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC4CC4)CC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C28H39F3N4O/c1-20-3-2-12-34(20)23-8-13-33(19-23)22-6-7-25(24(17-22)28(29,30)31)35-16-11-27(26(35)36)9-14-32(15-10-27)18-21-4-5-21/h6-7,17,20-21,23H,2-5,8-16,18-19H2,1H3/t20-,23-/s2
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1.40n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108286
PNG
(US8604046, 66)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(CC3)C(=O)c3ccoc3)C2=O)c(C)c1
Show InChI InChI=1/C30H40N4O3/c1-22-19-25(32-15-8-26(20-32)33-13-3-5-23(33)2)6-7-27(22)34-14-4-10-30(29(34)36)11-16-31(17-12-30)28(35)24-9-18-37-21-24/h6-7,9,18-19,21,23,26H,3-5,8,10-17,20H2,1-2H3/t23-,26-/s2
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1.60n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108312
PNG
(US8604046, 92)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCC2(CCN(CC2)S(=O)(=O)c2ccc(F)cc2)C1=O
Show InChI InChI=1/C30H39FN4O3S/c1-23-4-2-3-17-34(23)27-13-18-32(22-27)25-7-9-26(10-8-25)35-21-16-30(29(35)36)14-19-33(20-15-30)39(37,38)28-11-5-24(31)6-12-28/h5-12,23,27H,2-4,13-22H2,1H3/t23-,27-/s2
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1.90n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108314
PNG
(US8604046, 94)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC3)C(=O)C3CCCC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C31H43F3N4O2/c1-22-6-4-5-15-37(22)25-11-16-36(21-25)24-9-10-27(26(20-24)31(32,33)34)38-19-14-30(29(38)40)12-17-35(18-13-30)28(39)23-7-2-3-8-23/h9-10,20,22-23,25H,2-8,11-19,21H2,1H3/t22-,25-/s2
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2.10n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108313
PNG
(US8604046, 93)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCC2(CCN(CC2)C(=O)C2CCOCC2)C1=O
Show InChI InChI=1/C30H44N4O3/c1-23-4-2-3-15-33(23)27-9-16-32(22-27)25-5-7-26(8-6-25)34-19-14-30(29(34)36)12-17-31(18-13-30)28(35)24-10-20-37-21-11-24/h5-8,23-24,27H,2-4,9-22H2,1H3/t23-,27-/s2
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3.30n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108285
PNG
(US8604046, 65)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(CC3)C(=O)c3ccncc3)C2=O)c(C)c1
Show InChI InChI=1/C31H41N5O2/c1-23-21-26(34-18-10-27(22-34)35-16-3-5-24(35)2)6-7-28(23)36-17-4-11-31(30(36)38)12-19-33(20-13-31)29(37)25-8-14-32-15-9-25/h6-9,14-15,21,24,27H,3-5,10-13,16-20,22H2,1-2H3/t24-,27-/s2
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4n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108327
PNG
(US8604046, 107)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC4CCOCC4)CC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C30H43F3N4O2/c1-22-3-2-12-36(22)25-6-13-35(21-25)24-4-5-27(26(19-24)30(31,32)33)37-16-11-29(28(37)38)9-14-34(15-10-29)20-23-7-17-39-18-8-23/h4-5,19,22-23,25H,2-3,6-18,20-21H2,1H3/t22-,25-/s2
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4.20n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108302
PNG
(US8604046, 82)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC3)C(=O)OC(C)(C)C)C2=O)c(F)c1
Show InChI InChI=1/C29H43FN4O3/c1-21-7-5-6-14-33(21)23-10-15-32(20-23)22-8-9-25(24(30)19-22)34-18-13-29(26(34)35)11-16-31(17-12-29)27(36)37-28(2,3)4/h8-9,19,21,23H,5-7,10-18,20H2,1-4H3/t21-,23-/s2
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4.30n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108318
PNG
(US8604046, 98)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC4CCOCC4)CC3)C2=O)c(F)c1
Show InChI InChI=1/C30H45FN4O2/c1-23-4-2-3-13-34(23)26-7-14-33(22-26)25-5-6-28(27(31)20-25)35-17-12-30(29(35)36)10-15-32(16-11-30)21-24-8-18-37-19-9-24/h5-6,20,23-24,26H,2-4,7-19,21-22H2,1H3/t23-,26-/s2
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4.60n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108325
PNG
(US8604046, 105)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(Cc4ccco4)CC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1/C29H37F3N4O2/c1-21-4-2-12-35(21)23-8-13-34(19-23)22-6-7-26(25(18-22)29(30,31)32)36-16-11-28(27(36)37)9-14-33(15-10-28)20-24-5-3-17-38-24/h3,5-7,17-18,21,23H,2,4,8-16,19-20H2,1H3/t21-,23-/s2
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5.5n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108273
PNG
(US8604046, 53)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(N2CCC3(CCN(CC4CCCC4)CC3)C2=O)c(C)c1
Show InChI InChI=1/C30H46N4O/c1-23-20-26(32-16-11-27(22-32)33-15-5-6-24(33)2)9-10-28(23)34-19-14-30(29(34)35)12-17-31(18-13-30)21-25-7-3-4-8-25/h9-10,20,24-25,27H,3-8,11-19,21-22H2,1-2H3
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5.60n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108300
PNG
(US8604046, 80)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCC2(CCN(CC2)C(=O)OC(C)(C)C)C1=O
Show InChI InChI=1/C29H44N4O3/c1-22-7-5-6-16-32(22)25-12-17-31(21-25)23-8-10-24(11-9-23)33-20-15-29(26(33)34)13-18-30(19-14-29)27(35)36-28(2,3)4/h8-11,22,25H,5-7,12-21H2,1-4H3/t22-,25-/s2
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5.60n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108277
PNG
(US8604046, 57)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(N2CCC3(CCN(CC3)C(=O)c3ccc(OC(F)(F)F)cc3)C2=O)c(C)c1
Show InChI InChI=1/C32H39F3N4O3/c1-22-20-25(37-16-11-26(21-37)38-15-3-4-23(38)2)7-10-28(22)39-19-14-31(30(39)41)12-17-36(18-13-31)29(40)24-5-8-27(9-6-24)42-32(33,34)35/h5-10,20,23,26H,3-4,11-19,21H2,1-2H3
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6.20n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108279
PNG
(US8604046, 59)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(CC3)C(=O)OC(C)(C)C)C2=O)c(C)c1
Show InChI InChI=1/C30H46N4O3/c1-22-20-24(32-17-11-25(21-32)33-15-6-8-23(33)2)9-10-26(22)34-16-7-12-30(27(34)35)13-18-31(19-14-30)28(36)37-29(3,4)5/h9-10,20,23,25H,6-8,11-19,21H2,1-5H3/t23-,25-/s2
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6.80n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair
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