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Found 19 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 6461
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM130382(4methyl6{[(3R,4R)4{[5(pyridin2 yl)pentyl]oxy}pyrro...)
Affinity DataKd:  212nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  1.19E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM130382(4methyl6{[(3R,4R)4{[5(pyridin2 yl)pentyl]oxy}pyrro...)
Affinity DataKd:  4.13E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  198nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,M336V,D597N](Rattus norvegicus (rats))
University Of California Irvine

LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  393nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  5.58E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial [1-973,L111A](Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM130383(4methyl6{[(3R,4R)4{[5(4methylpyridin2 yl)pentyl]ox...)
Affinity DataKd:  7.27E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  50nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,M336V,D597N](Rattus norvegicus (rats))
University Of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  153nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,H341L](Rattus norvegicus (rats))
University Of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  352nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  1.60E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial [1-973,Y477A](Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  3.49E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial [1-973,L111A](Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM130384(6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl...)
Affinity DataKd:  1.18E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  30nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,M336V,D597N](Rattus norvegicus (rats))
University Of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  265nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,H341L](Rattus norvegicus (rats))
University Of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  632nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  1.06E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial [1-973,Y477A](Bos taurus (bovine))
University Of California Irvine

LigandPNGBDBM130385(6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...)
Affinity DataKd:  1.54E+4nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,M336V,D597N](Rattus norvegicus (rats))
University Of California Irvine

LigandPNGBDBM130382(4methyl6{[(3R,4R)4{[5(pyridin2 yl)pentyl]oxy}pyrro...)
Affinity DataKd:  1.93E+3nMpH: 7.5 T: 2°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair