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Compile Data Set for Download or QSAR

Found 130 hits of ph data with Target = 'α-glucosidase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 3.83E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Typically, α-glucosidase activity was assayed in 50 mM phosphate buffer (pH 6.8) containing 5% v/v DMSO and PNP glycoside was used as a substrat...


Bioorg Chem 58: 81-7 (2015)


Article DOI: 10.1016/j.bioorg.2014.12.001
BindingDB Entry DOI: 10.7270/Q2JQ0ZR8
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152612
PNG
((E)-4-(4-Chlorophenyl)-2-(2-(3-nitrobenzylidene)hy...)
Show SMILES [O-][N+](=O)c1cccc(\C=N\Nc2nc(cs2)-c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C16H11ClN4O2S/c17-13-6-4-12(5-7-13)15-10-24-16(19-15)20-18-9-11-2-1-3-14(8-11)21(22)23/h1-10H,(H,19,20)/b18-9+
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n/an/a 2.20E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152613
PNG
((E)-2-(2-(1-(2-Bromo-4-nitrophenyl)ethylidene)hydr...)
Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1ccc(cc1Br)[N+]([O-])=O
Show InChI InChI=1S/C17H12BrClN4O2S/c1-10(14-7-6-13(23(24)25)8-15(14)18)21-22-17-20-16(9-26-17)11-2-4-12(19)5-3-11/h2-9H,1H3,(H,20,22)/b21-10+
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n/an/a 4.33E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152614
PNG
((E)-4-(4-Chlorophenyl)-2-(2-(2-nitrobenzylidene)hy...)
Show SMILES [O-][N+](=O)c1ccccc1\C=N\Nc1nc(cs1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H11ClN4O2S/c17-13-7-5-11(6-8-13)14-10-24-16(19-14)20-18-9-12-3-1-2-4-15(12)21(22)23/h1-10H,(H,19,20)/b18-9+
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n/an/a 2.39E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152615
PNG
((E)-4-(4-Chlorophenyl)-2-(2-(1-(4-(piperidin-1-yl)...)
Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCCCC1
Show InChI InChI=1S/C22H23ClN4S/c1-16(17-7-11-20(12-8-17)27-13-3-2-4-14-27)25-26-22-24-21(15-28-22)18-5-9-19(23)10-6-18/h5-12,15H,2-4,13-14H2,1H3,(H,24,26)/b25-16+
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n/an/a 3.88E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152616
PNG
((E)-4-((2-(4-(4-Chlorophenyl)thiazol-2-yl)hydrazon...)
Show SMILES CN(C)c1ccc(\C=N\Nc2nc(cs2)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C18H17ClN4S/c1-23(2)16-9-3-13(4-10-16)11-20-22-18-21-17(12-24-18)14-5-7-15(19)8-6-14/h3-12H,1-2H3,(H,21,22)/b20-11+
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n/an/a 2.05E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152617
PNG
((E)-4-(4-Chlorophenyl)-2-(2-(naphthalene-2-yl-meth...)
Show SMILES Clc1ccc(cc1)-c1csc(N\N=C\c2ccc3ccccc3c2)n1
Show InChI InChI=1S/C20H14ClN3S/c21-18-9-7-16(8-10-18)19-13-25-20(23-19)24-22-12-14-5-6-15-3-1-2-4-17(15)11-14/h1-13H,(H,23,24)/b22-12+
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n/an/a 1.75E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152618
PNG
((E)-2-(2-(4-(Benzyloxy)benzylidene)hydrazinyl)-4-(...)
Show SMILES Clc1ccc(cc1)-c1csc(N\N=C\c2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C23H18ClN3OS/c24-20-10-8-19(9-11-20)22-16-29-23(26-22)27-25-14-17-6-12-21(13-7-17)28-15-18-4-2-1-3-5-18/h1-14,16H,15H2,(H,26,27)/b25-14+
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n/an/a 3.68E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152619
PNG
((E)-2,6-Di-t-butyl-4-((2-(4-(4-Chlorophenyl)thiazo...)
Show SMILES CC(C)(C)c1cc(\C=N\Nc2nc(cs2)-c2ccc(Cl)cc2)cc(c1O)C(C)(C)C
Show InChI InChI=1S/C24H28ClN3OS/c1-23(2,3)18-11-15(12-19(21(18)29)24(4,5)6)13-26-28-22-27-20(14-30-22)16-7-9-17(25)10-8-16/h7-14,29H,1-6H3,(H,27,28)/b26-13+
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n/an/a 1.82E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152620
PNG
(1-((E)-(2-(4-(4-chlorophenyl)thiazol-2-yl)hydrazon...)
Show SMILES Clc1ccc(cc1)-c1csc(N\N=C\c2cccc(\C=N/Nc3nc(cs3)-c3ccc(Cl)cc3)c2)n1
Show InChI InChI=1S/C26H18Cl2N6S2/c27-21-8-4-19(5-9-21)23-15-35-25(31-23)33-29-13-17-2-1-3-18(12-17)14-30-34-26-32-24(16-36-26)20-6-10-22(28)11-7-20/h1-16H,(H,31,33)(H,32,34)/b29-13-,30-14+
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n/an/a 6.85E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152621
PNG
(5-(4-chlorophenyl)-2-((E)-2-(4-((E)-(2-(4-(4-chlor...)
Show SMILES Clc1ccc(cc1)-c1csc(N\N=C\c2ccc(\C=N\Nc3ncc(s3)-c3ccc(Cl)cc3)cc2)n1
Show InChI InChI=1S/C26H18Cl2N6S2/c27-21-9-5-19(6-10-21)23-16-35-26(32-23)34-31-14-18-3-1-17(2-4-18)13-30-33-25-29-15-24(36-25)20-7-11-22(28)12-8-20/h1-16H,(H,29,33)(H,32,34)/b30-13+,31-14+
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n/an/a 3.42E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152622
PNG
((E)-5-((2-(4-(4-Chlorophenyl)thiazole-2-yl)hydrazo...)
Show SMILES COc1ccc(\C=N\Nc2nc(cs2)-c2ccc(Cl)cc2)cc1O
Show InChI InChI=1S/C17H14ClN3O2S/c1-23-16-7-2-11(8-15(16)22)9-19-21-17-20-14(10-24-17)12-3-5-13(18)6-4-12/h2-10,22H,1H3,(H,20,21)/b19-9+
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n/an/a 1.76E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152623
PNG
((E)-4-(4-Methoxyphenyl)-2-(2-(1-(3- nitrophenyl)-e...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C(/C)c2cccc(c2)[N+]([O-])=O)n1
Show InChI InChI=1S/C18H16N4O3S/c1-12(14-4-3-5-15(10-14)22(23)24)20-21-18-19-17(11-26-18)13-6-8-16(25-2)9-7-13/h3-11H,1-2H3,(H,19,21)/b20-12+
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n/an/a 4.24E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152624
PNG
((E)-2-(2-(Anthracen-9-ylmethylene)hydrazinyl)-4-(4...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2c3ccccc3cc3ccccc23)n1
Show InChI InChI=1S/C25H19N3OS/c1-29-20-12-10-17(11-13-20)24-16-30-25(27-24)28-26-15-23-21-8-4-2-6-18(21)14-19-7-3-5-9-22(19)23/h2-16H,1H3,(H,27,28)/b26-15+
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n/an/a 1.92E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152625
PNG
((E)-4-((2-(4-(4-Methoxyphenyl)thiazol-2-yl)hydrazo...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2ccc(cc2)N(C)C)n1
Show InChI InChI=1S/C19H20N4OS/c1-23(2)16-8-4-14(5-9-16)12-20-22-19-21-18(13-25-19)15-6-10-17(24-3)11-7-15/h4-13H,1-3H3,(H,21,22)/b20-12+
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n/an/a 1.46E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152626
PNG
((E)-4-(4-Methoxyphenyl)-2-(2-(naphthalen-2-yl-meth...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2ccc3ccccc3c2)n1
Show InChI InChI=1S/C21H17N3OS/c1-25-19-10-8-17(9-11-19)20-14-26-21(23-20)24-22-13-15-6-7-16-4-2-3-5-18(16)12-15/h2-14H,1H3,(H,23,24)/b22-13+
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n/an/a 1.94E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152627
PNG
((E)-2-(2-(4-(Benzyloxy)benzylidene)hydrazinyl)-4-(...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2ccc(OCc3ccccc3)cc2)n1
Show InChI InChI=1S/C24H21N3O2S/c1-28-21-13-9-20(10-14-21)23-17-30-24(26-23)27-25-15-18-7-11-22(12-8-18)29-16-19-5-3-2-4-6-19/h2-15,17H,16H2,1H3,(H,26,27)/b25-15+
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n/an/a 9.92E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152628
PNG
((E)-2,6-Di-tert-butyl-4-((2-(4-(4-Methoxyphenyl)th...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)n1
Show InChI InChI=1S/C25H31N3O2S/c1-24(2,3)19-12-16(13-20(22(19)29)25(4,5)6)14-26-28-23-27-21(15-31-23)17-8-10-18(30-7)11-9-17/h8-15,29H,1-7H3,(H,27,28)/b26-14+
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n/an/a 1.23E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152629
PNG
(1-((E)-(2-(4-(4-Methoxyphenyl)thiazol-2-yl)hydrazo...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2cccc(\C=N/Nc3nc(cs3)-c3ccc(OC)cc3)c2)n1
Show InChI InChI=1S/C28H24N6O2S2/c1-35-23-10-6-21(7-11-23)25-17-37-27(31-25)33-29-15-19-4-3-5-20(14-19)16-30-34-28-32-26(18-38-28)22-8-12-24(36-2)13-9-22/h3-18H,1-2H3,(H,31,33)(H,32,34)/b29-15-,30-16+
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n/an/a 5.54E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152630
PNG
(5-(4-methoxyphenyl)-2-((E)-2-(4-((E)-(2-(4-(4-meth...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2ccc(\C=N\Nc3ncc(s3)-c3ccc(OC)cc3)cc2)n1
Show InChI InChI=1S/C28H24N6O2S2/c1-35-23-11-7-21(8-12-23)25-18-37-28(32-25)34-31-16-20-5-3-19(4-6-20)15-30-33-27-29-17-26(38-27)22-9-13-24(36-2)14-10-22/h3-18H,1-2H3,(H,29,33)(H,32,34)/b30-15+,31-16+
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n/an/a 2.26E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152631
PNG
((E)-2-Methoxy-5-((2-(4-(4-methoxyphenyl)thiazol-2-...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2ccc(OC)c(O)c2)n1
Show InChI InChI=1S/C18H17N3O3S/c1-23-14-6-4-13(5-7-14)15-11-25-18(20-15)21-19-10-12-3-8-17(24-2)16(22)9-12/h3-11,22H,1-2H3,(H,20,21)/b19-10+
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n/an/a 1.76E+5n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM152632
PNG
((E)-4-((2-(4-(4-Methoxyphenyl)thiazol-2-yl)hydrazo...)
Show SMILES COc1ccc(cc1)-c1csc(N\N=C\c2ccc(O)c(O)c2)n1
Show InChI InChI=1S/C17H15N3O3S/c1-23-13-5-3-12(4-6-13)14-10-24-17(19-14)20-18-9-11-2-7-15(21)16(22)8-11/h2-10,21-22H,1H3,(H,19,20)/b18-9+
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n/an/a 4.64E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 3.83E+4n/an/an/an/a6.8n/a



Hazara University



Assay Description
Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit...


Bioorg Chem 62: 15-21 (2015)


Article DOI: 10.1016/j.bioorg.2015.06.006
BindingDB Entry DOI: 10.7270/Q24B302B
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178001
PNG
((E)-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)prop-2-...)
Show SMILES Oc1cccc(\C=C\C(=O)c2ccccc2O)c1
Show InChI InChI=1S/C15H12O3/c16-12-5-3-4-11(10-12)8-9-15(18)13-6-1-2-7-14(13)17/h1-10,16-17H/b9-8+
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n/an/a 4.47E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50431165
PNG
(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Show SMILES Oc1cccc(c1)-c1cc(=O)c2ccccc2o1
Show InChI InChI=1S/C15H10O3/c16-11-5-3-4-10(8-11)15-9-13(17)12-6-1-2-7-14(12)18-15/h1-9,16H
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n/an/a 3.47E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178002
PNG
(2-(3-((4-nitrobenzyl)oxy)phenyl)-4H-chromen-4-one ...)
Show SMILES [O-][N+](=O)c1ccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)cc1
Show InChI InChI=1S/C22H15NO5/c24-20-13-22(28-21-7-2-1-6-19(20)21)16-4-3-5-18(12-16)27-14-15-8-10-17(11-9-15)23(25)26/h1-13H,14H2
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n/an/a 3.64E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178003
PNG
(2-(3-(benzyloxy)phenyl)-4H-chromen-4-one (4))
Show SMILES O=c1cc(oc2ccccc12)-c1cccc(OCc2ccccc2)c1
Show InChI InChI=1S/C22H16O3/c23-20-14-22(25-21-12-5-4-11-19(20)21)17-9-6-10-18(13-17)24-15-16-7-2-1-3-8-16/h1-14H,15H2
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n/an/a 5.97E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178004
PNG
(2-(3-((3-(trifluoromethyl)benzyl)oxy)phenyl)-4H-ch...)
Show SMILES FC(F)(F)c1ccc(c(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)c1)C(F)(F)F
Show InChI InChI=1S/C23H15F3O3/c24-23(25,26)17-7-3-5-15(11-17)14-28-18-8-4-6-16(12-18)22-13-20(27)19-9-1-2-10-21(19)29-22/h1-13H,14H2
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n/an/a 5.45E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178005
PNG
(2-(3-((4-(tert-butyl)benzyl)oxy)phenyl)-4H-chromen...)
Show SMILES CC(C)(C)c1ccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)cc1
Show InChI InChI=1S/C26H24O3/c1-26(2,3)20-13-11-18(12-14-20)17-28-21-8-6-7-19(15-21)25-16-23(27)22-9-4-5-10-24(22)29-25/h4-16H,17H2,1-3H3
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n/an/a 4.95E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178004
PNG
(2-(3-((3-(trifluoromethyl)benzyl)oxy)phenyl)-4H-ch...)
Show SMILES FC(F)(F)c1ccc(c(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)c1)C(F)(F)F
Show InChI InChI=1S/C23H15F3O3/c24-23(25,26)17-7-3-5-15(11-17)14-28-18-8-4-6-16(12-18)22-13-20(27)19-9-1-2-10-21(19)29-22/h1-13H,14H2
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n/an/a 1.26E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178007
PNG
(2-(3-((3-((trifluoromethyl)thio)benzyl)oxy)phenyl)...)
Show SMILES FC(F)(F)Sc1cccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)c1
Show InChI InChI=1S/C23H15F3O3S/c24-23(25,26)30-18-8-3-5-15(11-18)14-28-17-7-4-6-16(12-17)22-13-20(27)19-9-1-2-10-21(19)29-22/h1-13H,14H2
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n/an/a 8.66E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178008
PNG
(4-((3-(4-oxo-4H-chromen-2-yl)phenoxy)methyl)benzon...)
Show SMILES O=c1cc(oc2ccccc12)-c1cccc(OCc2ccc(cc2)C#N)c1
Show InChI InChI=1S/C23H15NO3/c24-14-16-8-10-17(11-9-16)15-26-19-5-3-4-18(12-19)23-13-21(25)20-6-1-2-7-22(20)27-23/h1-13H,15H2
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n/an/a 3.47E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178009
PNG
(2-(3-((4-methoxybenzyl)oxy)phenyl)-4H-chromen-4-on...)
Show SMILES COc1ccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)cc1
Show InChI InChI=1S/C23H18O4/c1-25-18-11-9-16(10-12-18)15-26-19-6-4-5-17(13-19)23-14-21(24)20-7-2-3-8-22(20)27-23/h2-14H,15H2,1H3
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n/an/a 3.54E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178010
PNG
(2-(3-((2,3-difluorobenzyl)oxy)phenyl)-4H-chromen-4...)
Show SMILES Fc1cccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)c1F
Show InChI InChI=1S/C22H14F2O3/c23-18-9-4-6-15(22(18)24)13-26-16-7-3-5-14(11-16)21-12-19(25)17-8-1-2-10-20(17)27-21/h1-12H,13H2
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n/an/a 3.49E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178011
PNG
(2-(3-((3-methylbenzyl)oxy)phenyl)-4H-chromen-4-one...)
Show SMILES Cc1cccc(COc2cccc(c2)-c2cc(=O)c3ccccc3o2)c1
Show InChI InChI=1S/C23H18O3/c1-16-6-4-7-17(12-16)15-25-19-9-5-8-18(13-19)23-14-21(24)20-10-2-3-11-22(20)26-23/h2-14H,15H2,1H3
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n/an/a 8.87E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM178012
PNG
(3-((3-(4-oxo-4H-chromen-2-yl)phenoxy)methyl)benzon...)
Show SMILES O=c1cc(oc2ccccc12)-c1cccc(OCc2cccc(c2)C#N)c1
Show InChI InChI=1S/C23H15NO3/c24-14-16-5-3-6-17(11-16)15-26-19-8-4-7-18(12-19)23-13-21(25)20-9-1-2-10-22(20)27-23/h1-13H,15H2
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n/an/a 3.86E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM23406
PNG
((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1
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PubMed
n/an/a 3.83E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA



Assay Description
The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...


Chem Biol Drug Des 87: 361-73 (2016)


Article DOI: 10.1111/cbdd.12666
BindingDB Entry DOI: 10.7270/Q2HQ3XPS
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175306
PNG
((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1ccc(O)cc1
Show InChI InChI=1S/C23H20N4O2/c1-14-11-20-21(12-15(14)2)26-22(25-20)17-5-7-18(8-6-17)23(29)27-24-13-16-3-9-19(28)10-4-16/h3-13,28H,1-2H3,(H,25,26)(H,27,29)/b24-13+
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n/an/a 2.60E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175307
PNG
((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1cccc(O)c1
Show InChI InChI=1S/C23H20N4O2/c1-14-10-20-21(11-15(14)2)26-22(25-20)17-6-8-18(9-7-17)23(29)27-24-13-16-4-3-5-19(28)12-16/h3-13,28H,1-2H3,(H,25,26)(H,27,29)/b24-13+
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n/an/a 3.25E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175308
PNG
((E)-N'-(3,4-dimethoxybenzylidene)-4-(5,6-dimet...)
Show SMILES COc1ccc(\C=N\NC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1OC
Show InChI InChI=1S/C25H24N4O3/c1-15-11-20-21(12-16(15)2)28-24(27-20)18-6-8-19(9-7-18)25(30)29-26-14-17-5-10-22(31-3)23(13-17)32-4/h5-14H,1-4H3,(H,27,28)(H,29,30)/b26-14+
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n/an/a 1.80E+5n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175309
PNG
((E)-N'-(2,5-dihydroxybenzylidene)-4-(5,6-dimet...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1cc(O)ccc1O
Show InChI InChI=1S/C23H20N4O3/c1-13-9-19-20(10-14(13)2)26-22(25-19)15-3-5-16(6-4-15)23(30)27-24-12-17-11-18(28)7-8-21(17)29/h3-12,28-29H,1-2H3,(H,25,26)(H,27,30)/b24-12+
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n/an/a 8.74E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175310
PNG
((E)-N'-(2,3-dihydroxybenzylidene)-4-(5,6-dimet...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1cccc(O)c1O
Show InChI InChI=1S/C23H20N4O3/c1-13-10-18-19(11-14(13)2)26-22(25-18)15-6-8-16(9-7-15)23(30)27-24-12-17-4-3-5-20(28)21(17)29/h3-12,28-29H,1-2H3,(H,25,26)(H,27,30)/b24-12+
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PubMed
n/an/a 9.99E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175311
PNG
((E)-N'-(2,4-dihydroxybenzylidene)-4-(5,6-dimet...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1ccc(O)cc1O
Show InChI InChI=1S/C23H20N4O3/c1-13-9-19-20(10-14(13)2)26-22(25-19)15-3-5-16(6-4-15)23(30)27-24-12-17-7-8-18(28)11-21(17)29/h3-12,28-29H,1-2H3,(H,25,26)(H,27,30)/b24-12+
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n/an/a 8.74E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175312
PNG
((E)-N'-(3,4-dihydroxybenzylidene)-4-(5,6-dimet...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C23H20N4O3/c1-13-9-18-19(10-14(13)2)26-22(25-18)16-4-6-17(7-5-16)23(30)27-24-12-15-3-8-20(28)21(29)11-15/h3-12,28-29H,1-2H3,(H,25,26)(H,27,30)/b24-12+
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n/an/a 1.25E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175313
PNG
((E)-N'-(3-chlorobenzylidene)-4-(5,6-dimethyl-1...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1cccc(Cl)c1
Show InChI InChI=1S/C23H19ClN4O/c1-14-10-20-21(11-15(14)2)27-22(26-20)17-6-8-18(9-7-17)23(29)28-25-13-16-4-3-5-19(24)12-16/h3-13H,1-2H3,(H,26,27)(H,28,29)/b25-13+
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n/an/a 2.24E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175314
PNG
((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Show SMILES COc1ccc(\C=N\NC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1O
Show InChI InChI=1S/C24H22N4O3/c1-14-10-19-20(11-15(14)2)27-23(26-19)17-5-7-18(8-6-17)24(30)28-25-13-16-4-9-22(31-3)21(29)12-16/h4-13,29H,1-3H3,(H,26,27)(H,28,30)/b25-13+
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n/an/a 2.90E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175315
PNG
((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Show SMILES COc1ccc(\C=N\NC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)c(O)c1
Show InChI InChI=1S/C24H22N4O3/c1-14-10-20-21(11-15(14)2)27-23(26-20)16-4-6-17(7-5-16)24(30)28-25-13-18-8-9-19(31-3)12-22(18)29/h4-13,29H,1-3H3,(H,26,27)(H,28,30)/b25-13+
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n/an/a 8.44E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175316
PNG
((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1ccncc1
Show InChI InChI=1S/C22H19N5O/c1-14-11-19-20(12-15(14)2)26-21(25-19)17-3-5-18(6-4-17)22(28)27-24-13-16-7-9-23-10-8-16/h3-13H,1-2H3,(H,25,26)(H,27,28)/b24-13+
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PubMed
n/an/a 1.48E+5n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175317
PNG
((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Show SMILES COc1ccc(O)c(\C=N\NC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)c1
Show InChI InChI=1S/C24H22N4O3/c1-14-10-20-21(11-15(14)2)27-23(26-20)16-4-6-17(7-5-16)24(30)28-25-13-18-12-19(31-3)8-9-22(18)29/h4-13,29H,1-3H3,(H,26,27)(H,28,30)/b25-13+
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n/an/a 8.44E+3n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175318
PNG
((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Show SMILES Cc1ccccc1\C=N\NC(=O)c1ccc(cc1)-c1nc2cc(C)c(C)cc2[nH]1
Show InChI InChI=1S/C24H22N4O/c1-15-6-4-5-7-20(15)14-25-28-24(29)19-10-8-18(9-11-19)23-26-21-12-16(2)17(3)13-22(21)27-23/h4-14H,1-3H3,(H,26,27)(H,28,29)/b25-14+
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n/an/a 2.48E+4n/an/an/an/a6.8n/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)


Article DOI: 10.1016/j.bioorg.2015.11.006
BindingDB Entry DOI: 10.7270/Q2W37V2M
More data for this
Ligand-Target Pair
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