BindingDB PrimarySearch

Found 2 hits of ph data with Target = '3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (V143T/T222A)'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (V143T/T222A) (Homo sapiens (human))	BDBM2691 (3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...) Show SMILES Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.5	30
University of Dundee					Assay Description In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...				Structure 12: 215-26 (2004) Article DOI: 10.1016/j.str.2004.01.005 BindingDB Entry DOI: 10.7270/Q2SJ1HV2
University of Dundee					More data for this Ligand-Target Pair				3D Structure (crystal)
3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Mutant (V143T/T222A) (Homo sapiens (human))	BDBM17055 ((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...) Show SMILES Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	7.5	30
University of Dundee					Assay Description In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...				Structure 12: 215-26 (2004) Article DOI: 10.1016/j.str.2004.01.005 BindingDB Entry DOI: 10.7270/Q2SJ1HV2
University of Dundee					More data for this Ligand-Target Pair				3D Structure (crystal)