Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1D (Homo sapiens (human)) | BDBM28574![]() (1-sulfonylindazole, 6c | 3-amino-N-[1-(naphthalene...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | >2.00E+3 | >-32.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Wyeth Research | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2413-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.071 BindingDB Entry DOI: 10.7270/Q28K77CF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (human)) | BDBM28580![]() (1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | >2.00E+3 | >-32.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Wyeth Research | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2413-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.071 BindingDB Entry DOI: 10.7270/Q28K77CF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (human)) | BDBM28579![]() (1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | >2.00E+3 | >-32.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Wyeth Research | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2413-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.071 BindingDB Entry DOI: 10.7270/Q28K77CF | |||||||||||
More data for this Ligand-Target Pair |