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Compile Data Set for Download or QSAR

Found 4 hits of ph data with Target = 'Acetylpolyamine amidohydrolase (APAH)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylpolyamine amidohydrolase (APAH)


(Mycoplana ramosa (Gram-negative bacterium))
BDBM152728
PNG
(5-Amino-N-hydroxypentanamide (4))
Show SMILES [NH3+]CCCCC(=O)NO
Show InChI InChI=1S/C5H12N2O2/c6-4-2-1-3-5(8)7-9/h9H,1-4,6H2,(H,7,8)/p+1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 170n/an/an/an/a8.2n/a



University of Pennsylvania



Assay Description
Activity assays were conducted at 25 C and contained 250 nM APAH (∼50% Zn2+ occupancy), 150 μM substrate, and 0−250 μM inhibit...


Biochemistry 54: 4692-703 (2015)


Article DOI: 10.1021/acs.biochem.5b00536
BindingDB Entry DOI: 10.7270/Q2FN14ZS
More data for this
Ligand-Target Pair
Acetylpolyamine amidohydrolase (APAH)


(Mycoplana ramosa (Gram-negative bacterium))
BDBM152731
PNG
(8-Amino-N-hydroxypentanamide (7))
Show SMILES [NH3+]CCCCCCCC(=O)NO
Show InChI InChI=1S/C8H18N2O2/c9-7-5-3-1-2-4-6-8(11)10-12/h12H,1-7,9H2,(H,10,11)/p+1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 150n/an/an/an/a8.2n/a



University of Pennsylvania



Assay Description
Activity assays were conducted at 25 C and contained 250 nM APAH (∼50% Zn2+ occupancy), 150 μM substrate, and 0−250 μM inhibit...


Biochemistry 54: 4692-703 (2015)


Article DOI: 10.1021/acs.biochem.5b00536
BindingDB Entry DOI: 10.7270/Q2FN14ZS
More data for this
Ligand-Target Pair
Acetylpolyamine amidohydrolase (APAH)


(Mycoplana ramosa (Gram-negative bacterium))
BDBM152730
PNG
(7-Amino-N-hydroxypentanamide (6))
Show SMILES [NH3+]CCCCCCC(=O)NO
Show InChI InChI=1S/C7H16N2O2/c8-6-4-2-1-3-5-7(10)9-11/h11H,1-6,8H2,(H,9,10)/p+1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 68n/an/an/an/a8.2n/a



University of Pennsylvania



Assay Description
Activity assays were conducted at 25 C and contained 250 nM APAH (∼50% Zn2+ occupancy), 150 μM substrate, and 0−250 μM inhibit...


Biochemistry 54: 4692-703 (2015)


Article DOI: 10.1021/acs.biochem.5b00536
BindingDB Entry DOI: 10.7270/Q2FN14ZS
More data for this
Ligand-Target Pair
Acetylpolyamine amidohydrolase (APAH)


(Mycoplana ramosa (Gram-negative bacterium))
BDBM152729
PNG
(6-Amino-N-hydroxypentanamide (5))
Show SMILES [NH3+]CCCCCC(=O)NO
Show InChI InChI=1S/C6H14N2O2/c7-5-3-1-2-4-6(9)8-10/h10H,1-5,7H2,(H,8,9)/p+1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/a8.2n/a



University of Pennsylvania



Assay Description
Activity assays were conducted at 25 C and contained 250 nM APAH (∼50% Zn2+ occupancy), 150 μM substrate, and 0−250 μM inhibit...


Biochemistry 54: 4692-703 (2015)


Article DOI: 10.1021/acs.biochem.5b00536
BindingDB Entry DOI: 10.7270/Q2FN14ZS
More data for this
Ligand-Target Pair