BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 634 hits of ph data with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201506
PNG
(US9187424, 273)
Show SMILES COc1cnc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cn1
Show InChI InChI=1S/C30H28F6N4O4/c1-18-5-7-19(8-6-18)22-15-28(30(34,35)36,20-9-11-21(12-10-20)44-14-4-3-13-29(31,32)33)40-27(42)25(22)26(41)39-23-16-38-24(43-2)17-37-23/h5-12,16-17H,3-4,13-15H2,1-2H3,(H,40,42)(H,37,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/a7.425



Bristol-Myers Squibb Company

US Patent


Assay Description
MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201231
PNG
(US9187424, 1)
Show SMILES CCCCCC1(C)NC(=O)C(C#N)C(=C1)c1ccc(C)cc1
Show InChI InChI=1S/C19H24N2O/c1-4-5-6-11-19(3)12-16(17(13-20)18(22)21-19)15-9-7-14(2)8-10-15/h7-10,12,17H,4-6,11H2,1-3H3,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.05E+3n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201232
PNG
(US9187424, 2 | US9187424, 2-1)
Show SMILES Cc1ccc(cc1)C1=C(c2nnn[nH]2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H21F6N5O2/c1-14-3-5-15(6-4-14)18-13-22(24(28,29)30,31-21(36)19(18)20-32-34-35-33-20)16-7-9-17(10-8-16)37-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,31,36)(H,32,33,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201232
PNG
(US9187424, 2 | US9187424, 2-1)
Show SMILES Cc1ccc(cc1)C1=C(c2nnn[nH]2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H21F6N5O2/c1-14-3-5-15(6-4-14)18-13-22(24(28,29)30,31-21(36)19(18)20-32-34-35-33-20)16-7-9-17(10-8-16)37-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,31,36)(H,32,33,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201234
PNG
(US9187424, 2-2)
Show SMILES Cc1ccc(cc1)C1=C(c2nnn[nH]2)C(=O)N[C@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H21F6N5O2/c1-14-3-5-15(6-4-14)18-13-22(24(28,29)30,31-21(36)19(18)20-32-34-35-33-20)16-7-9-17(10-8-16)37-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,31,36)(H,32,33,34,35)/t22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 261n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201237
PNG
(US9187424, 5)
Show SMILES CCCCOc1ccc(cc1)C1(CC(=C(C#N)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23F3N2O2/c1-3-4-13-31-19-11-9-18(10-12-19)23(24(25,26)27)14-20(21(15-28)22(30)29-23)17-7-5-16(2)6-8-17/h5-12H,3-4,13-14H2,1-2H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM50442178
PNG
(CHEMBL2441600 | US9187424, 124)
Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C31H28F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(31(35,36)37,21-8-12-24(13-9-21)43-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-23(42-2)15-11-22/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 7n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201239
PNG
(US9187424, 6-2)
Show SMILES COc1ccc(NC(=O)C2=C(C[C@](NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C31H28F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(31(35,36)37,21-8-12-24(13-9-21)43-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-23(42-2)15-11-22/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)/t29-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201241
PNG
(US9187424, 8)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2nn[nH]n2)C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H26F6N6O3/c1-16-5-7-17(8-6-16)20-15-25(27(31,32)33,35-23(41)21(20)22(40)34-24-36-38-39-37-24)18-9-11-19(12-10-18)42-14-4-2-3-13-26(28,29)30/h5-12H,2-4,13-15H2,1H3,(H,35,41)(H2,34,36,37,38,39,40)/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM50442177
PNG
(CHEMBL2441599 | US9187424, 9)
Show SMILES CCn1nnc(n1)C1=C(CC(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(C)cc1
Show InChI InChI=1S/C26H25F6N5O2/c1-3-37-35-22(34-36-37)21-20(17-7-5-16(2)6-8-17)15-24(26(30,31)32,33-23(21)38)18-9-11-19(12-10-18)39-14-4-13-25(27,28)29/h5-12H,3-4,13-15H2,1-2H3,(H,33,38)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
US Patent
n/an/a 121n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201242
PNG
(US9187424, 10)
Show SMILES Cc1ccc(cc1)C1=C(c2nnc(o2)C(F)(F)F)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H20F9N3O3/c1-14-3-5-15(6-4-14)18-13-23(26(33,34)35,16-7-9-17(10-8-16)40-12-2-11-24(27,28)29)36-20(39)19(18)21-37-38-22(41-21)25(30,31)32/h3-10H,2,11-13H2,1H3,(H,36,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 138n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201243
PNG
(US9187424, 11)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(OC(F)(F)F)cc2)C(=O)NC(C)(C1)c1ccc(OCCCC(F)(F)F)cc1
Show InChI InChI=1S/C31H28F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(2,21-8-12-23(13-9-21)42-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-24(15-11-22)43-31(35,36)37/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201244
PNG
(US9187424, 12)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1cnn(CCCCC(F)(F)F)c1)C(F)(F)F
Show InChI InChI=1S/C22H21F6N7O/c1-13-4-6-14(7-5-13)16-10-20(22(26,27)28,30-19(36)17(16)18-31-33-34-32-18)15-11-29-35(12-15)9-3-2-8-21(23,24)25/h4-7,11-12H,2-3,8-10H2,1H3,(H,30,36)(H,31,32,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 374n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201245
PNG
(US9187424, 13)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)N(=O)=O
Show InChI InChI=1S/C23H20F6N2O4/c1-14-3-5-15(6-4-14)18-13-21(23(27,28)29,30-20(32)19(18)31(33)34)16-7-9-17(10-8-16)35-12-2-11-22(24,25)26/h3-10H,2,11-13H2,1H3,(H,30,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 35n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201246
PNG
(US9187424, 14)
Show SMILES COc1ccc(cc1)C1=C(C#N)C(=O)NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)C11CC1
Show InChI InChI=1S/C26H22F6N2O3/c1-36-18-7-3-16(4-8-18)21-20(15-33)22(35)34-25(26(30,31)32,23(21)12-13-23)17-5-9-19(10-6-17)37-14-2-11-24(27,28)29/h3-10H,2,11-14H2,1H3,(H,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.05E+3n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201247
PNG
(US9187424, 15-1 | US9187424, 15-2)
Show SMILES COc1ccc(cc1)C1=C[C@](NC(=O)C1(F)C#N)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H19F7N2O3/c1-35-17-7-3-15(4-8-17)19-13-22(24(29,30)31,33-20(34)21(19,25)14-32)16-5-9-18(10-6-16)36-12-2-11-23(26,27)28/h3-10,13H,2,11-12H2,1H3,(H,33,34)/t21?,22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201247
PNG
(US9187424, 15-1 | US9187424, 15-2)
Show SMILES COc1ccc(cc1)C1=C[C@](NC(=O)C1(F)C#N)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H19F7N2O3/c1-35-17-7-3-15(4-8-17)19-13-22(24(29,30)31,33-20(34)21(19,25)14-32)16-5-9-18(10-6-16)36-12-2-11-23(26,27)28/h3-10,13H,2,11-12H2,1H3,(H,33,34)/t21?,22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 431n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201249
PNG
(US9187424, 15-3 | US9187424, 15-4)
Show SMILES COc1ccc(cc1)C1=C[C@@](NC(=O)C1(F)C#N)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H19F7N2O3/c1-35-17-7-3-15(4-8-17)19-13-22(24(29,30)31,33-20(34)21(19,25)14-32)16-5-9-18(10-6-16)36-12-2-11-23(26,27)28/h3-10,13H,2,11-12H2,1H3,(H,33,34)/t21?,22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 756n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201249
PNG
(US9187424, 15-3 | US9187424, 15-4)
Show SMILES COc1ccc(cc1)C1=C[C@@](NC(=O)C1(F)C#N)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H19F7N2O3/c1-35-17-7-3-15(4-8-17)19-13-22(24(29,30)31,33-20(34)21(19,25)14-32)16-5-9-18(10-6-16)36-12-2-11-23(26,27)28/h3-10,13H,2,11-12H2,1H3,(H,33,34)/t21?,22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.05E+3n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201251
PNG
(US9187424, 16-1)
Show SMILES COc1ccc(NC(=O)C2C(C[C@](NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C31H30F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(31(35,36)37,21-8-12-24(13-9-21)43-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-23(42-2)15-11-22/h4-15,25-26H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)/t25?,26?,29-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201252
PNG
(US9187424, 16-2)
Show SMILES COc1ccc(NC(=O)C2C(C[C@@](NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C31H30F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(31(35,36)37,21-8-12-24(13-9-21)43-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-23(42-2)15-11-22/h4-15,25-26H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)/t25?,26?,29-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 416n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201269
PNG
(US9187424, 269 | US9187424, 33 | US9187424, 53 | U...)
Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H20F6N2O2/c1-15-3-5-16(6-4-15)19-13-22(24(28,29)30,32-21(33)20(19)14-31)17-7-9-18(10-8-17)34-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201270
PNG
(US9187424, 34)
Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCOC(C)(C)C)cc1)C(F)(F)F
Show InChI InChI=1S/C26H27F3N2O3/c1-17-5-7-18(8-6-17)21-15-25(26(27,28)29,31-23(32)22(21)16-30)19-9-11-20(12-10-19)33-13-14-34-24(2,3)4/h5-12H,13-15H2,1-4H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 126n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201271
PNG
(US9187424, 35)
Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCc2ccccc2)cc1)C(F)(F)F
Show InChI InChI=1S/C29H25F3N2O2/c1-20-9-11-22(12-10-20)25-18-28(29(30,31)32,34-27(35)26(25)19-33)23-13-15-24(16-14-23)36-17-5-8-21-6-3-2-4-7-21/h2-4,6-7,9-16H,5,8,17-18H2,1H3,(H,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201272
PNG
(US9187424, 36)
Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCC2CCCC2)cc1)C(F)(F)F
Show InChI InChI=1S/C27H27F3N2O2/c1-18-6-8-20(9-7-18)23-16-26(27(28,29)30,32-25(33)24(23)17-31)21-10-12-22(13-11-21)34-15-14-19-4-2-3-5-19/h6-13,19H,2-5,14-16H2,1H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 57n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201273
PNG
(US9187424, 37)
Show SMILES CC(C)CCOc1ccc(cc1)C1(CC(=C(C#N)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C25H25F3N2O2/c1-16(2)12-13-32-20-10-8-19(9-11-20)24(25(26,27)28)14-21(22(15-29)23(31)30-24)18-6-4-17(3)5-7-18/h4-11,16H,12-14H2,1-3H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201266
PNG
(US9187424, 30 | US9187424, 39)
Show SMILES COc1ccc(cc1)C1(CC(=C(C#N)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C21H17F3N2O2/c1-13-3-5-14(6-4-13)17-11-20(21(22,23)24,26-19(27)18(17)12-25)15-7-9-16(28-2)10-8-15/h3-10H,11H2,1-2H3,(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201276
PNG
(US9187424, 40)
Show SMILES COc1ccc(cc1)-c1ccc(cc1)C1(CC(=C(C#N)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C27H21F3N2O2/c1-17-3-5-20(6-4-17)23-15-26(27(28,29)30,32-25(33)24(23)16-31)21-11-7-18(8-12-21)19-9-13-22(34-2)14-10-19/h3-14H,15H2,1-2H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 164n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201277
PNG
(US9187424, 41)
Show SMILES COc1ccc(cc1)C1(CC(=C(C(=O)Nc2ccc(F)cc2)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C27H22F4N2O3/c1-16-3-5-17(6-4-16)22-15-26(27(29,30)31,18-7-13-21(36-2)14-8-18)33-25(35)23(22)24(34)32-20-11-9-19(28)10-12-20/h3-14H,15H2,1-2H3,(H,32,34)(H,33,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201278
PNG
(US9187424, 42)
Show SMILES CCCCCc1ccc(cc1)C1(CC(=C(C#N)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C25H25F3N2O/c1-3-4-5-6-18-9-13-20(14-10-18)24(25(26,27)28)15-21(22(16-29)23(31)30-24)19-11-7-17(2)8-12-19/h7-14H,3-6,15H2,1-2H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 77n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201279
PNG
(US9187424, 43)
Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(cc1)-c1ccccn1)C(F)(F)F
Show InChI InChI=1S/C25H18F3N3O/c1-16-5-7-17(8-6-16)20-14-24(25(26,27)28,31-23(32)21(20)15-29)19-11-9-18(10-12-19)22-4-2-3-13-30-22/h2-13H,14H2,1H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 60n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201284
PNG
(US9187424, 165 | US9187424, 48)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(F)cc2)C(=O)NC(C1)(c1ccc(Oc2ccccc2)cc1)C(F)(F)F
Show InChI InChI=1S/C32H24F4N2O3/c1-20-7-9-21(10-8-20)27-19-31(32(34,35)36,22-11-17-26(18-12-22)41-25-5-3-2-4-6-25)38-30(40)28(27)29(39)37-24-15-13-23(33)14-16-24/h2-18H,19H2,1H3,(H,37,39)(H,38,40)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201285
PNG
(US9187424, 49)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(F)cc2)C(=O)NC(C1)(c1ccc(Oc2ccncn2)cc1)C(F)(F)F
Show InChI InChI=1S/C30H22F4N4O3/c1-18-2-4-19(5-3-18)24-16-29(30(32,33)34,20-6-12-23(13-7-20)41-25-14-15-35-17-36-25)38-28(40)26(24)27(39)37-22-10-8-21(31)9-11-22/h2-15,17H,16H2,1H3,(H,37,39)(H,38,40)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 64n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201286
PNG
(US9187424, 50)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(F)cc2)C(=O)NC(C1)(c1ccc(cc1)-c1cnccn1)C(F)(F)F
Show InChI InChI=1S/C30H22F4N4O2/c1-18-2-4-19(5-3-18)24-16-29(30(32,33)34,21-8-6-20(7-9-21)25-17-35-14-15-36-25)38-28(40)26(24)27(39)37-23-12-10-22(31)11-13-23/h2-15,17H,16H2,1H3,(H,37,39)(H,38,40)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 95n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201287
PNG
(US9187424, 51)
Show SMILES CCCCCc1ccc(cc1)C1(CC(=C(C(=O)Nc2ccc(F)cc2)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C31H30F4N2O2/c1-3-4-5-6-21-9-13-23(14-10-21)30(31(33,34)35)19-26(22-11-7-20(2)8-12-22)27(29(39)37-30)28(38)36-25-17-15-24(32)16-18-25/h7-18H,3-6,19H2,1-2H3,(H,36,38)(H,37,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201288
PNG
(US9187424, 52)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(F)cc2)C(=O)NC(C1)(c1ccc(Oc2ncccn2)cc1)C(F)(F)F
Show InChI InChI=1S/C30H22F4N4O3/c1-18-3-5-19(6-4-18)24-17-29(30(32,33)34,20-7-13-23(14-8-20)41-28-35-15-2-16-36-28)38-27(40)25(24)26(39)37-22-11-9-21(31)10-12-22/h2-16H,17H2,1H3,(H,37,39)(H,38,40)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 99n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201269
PNG
(US9187424, 269 | US9187424, 33 | US9187424, 53 | U...)
Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H20F6N2O2/c1-15-3-5-16(6-4-15)19-13-22(24(28,29)30,32-21(33)20(19)14-31)17-7-9-18(10-8-17)34-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201290
PNG
(US9187424, 54)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(F)cc2)C(=O)NC(C1)(c1ccc(OCc2ccccc2)cc1)C(F)(F)F
Show InChI InChI=1S/C33H26F4N2O3/c1-21-7-9-23(10-8-21)28-19-32(33(35,36)37,24-11-17-27(18-12-24)42-20-22-5-3-2-4-6-22)39-31(41)29(28)30(40)38-26-15-13-25(34)14-16-26/h2-18H,19-20H2,1H3,(H,38,40)(H,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201291
PNG
(US9187424, 55)
Show SMILES CCCCCNC(=O)C1=C(CC(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(C)cc1
Show InChI InChI=1S/C29H32F6N2O3/c1-3-4-5-16-36-25(38)24-23(20-9-7-19(2)8-10-20)18-27(29(33,34)35,37-26(24)39)21-11-13-22(14-12-21)40-17-6-15-28(30,31)32/h7-14H,3-6,15-18H2,1-2H3,(H,36,38)(H,37,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201293
PNG
(US9187424, 57)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)NCCc2ccccc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C32H30F6N2O3/c1-21-8-10-23(11-9-21)26-20-30(32(36,37)38,24-12-14-25(15-13-24)43-19-5-17-31(33,34)35)40-29(42)27(26)28(41)39-18-16-22-6-3-2-4-7-22/h2-4,6-15H,5,16-20H2,1H3,(H,39,41)(H,40,42)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 16n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201294
PNG
(US9187424, 58)
Show SMILES COc1cccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)c1
Show InChI InChI=1S/C31H28F6N2O4/c1-19-7-9-20(10-8-19)25-18-29(31(35,36)37,21-11-13-23(14-12-21)43-16-4-15-30(32,33)34)39-28(41)26(25)27(40)38-22-5-3-6-24(17-22)42-2/h3,5-14,17H,4,15-16,18H2,1-2H3,(H,38,40)(H,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 29n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201295
PNG
(US9187424, 59)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccccc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C30H26F6N2O3/c1-19-8-10-20(11-9-19)24-18-28(30(34,35)36,21-12-14-23(15-13-21)41-17-5-16-29(31,32)33)38-27(40)25(24)26(39)37-22-6-3-2-4-7-22/h2-4,6-15H,5,16-18H2,1H3,(H,37,39)(H,38,40)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201296
PNG
(US9187424, 60)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccccc2Cl)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C30H25ClF6N2O3/c1-18-7-9-19(10-8-18)22-17-28(30(35,36)37,20-11-13-21(14-12-20)42-16-4-15-29(32,33)34)39-27(41)25(22)26(40)38-24-6-3-2-5-23(24)31/h2-3,5-14H,4,15-17H2,1H3,(H,38,40)(H,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201298
PNG
(US9187424, 62)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(Cl)cc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C30H25ClF6N2O3/c1-18-3-5-19(6-4-18)24-17-28(30(35,36)37,20-7-13-23(14-8-20)42-16-2-15-29(32,33)34)39-27(41)25(24)26(40)38-22-11-9-21(31)10-12-22/h3-14H,2,15-17H2,1H3,(H,38,40)(H,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 24n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201299
PNG
(US9187424, 147 | US9187424, 63)
Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C23H18F6N2O2/c1-14-2-4-15(5-3-14)18-12-21(23(27,28)29,31-20(32)19(18)13-30)16-6-8-17(9-7-16)33-11-10-22(24,25)26/h2-9H,10-12H2,1H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 28n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201300
PNG
(US9187424, 64)
Show SMILES COc1cccc(c1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H20F6N2O3/c1-34-18-5-2-4-15(12-18)19-13-22(24(28,29)30,32-21(33)20(19)14-31)16-6-8-17(9-7-16)35-11-3-10-23(25,26)27/h2,4-9,12H,3,10-11,13H2,1H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 280n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201301
PNG
(US9187424, 65 | US9187424, 77)
Show SMILES COc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H20F6N2O3/c1-34-17-7-3-15(4-8-17)19-13-22(24(28,29)30,32-21(33)20(19)14-31)16-5-9-18(10-6-16)35-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201302
PNG
(US9187424, 224 | US9187424, 66)
Show SMILES FC(F)(F)CCCOc1ccc(cc1)C1(CC(=C(C#N)C(=O)N1)c1ccc(cc1)C#N)C(F)(F)F
Show InChI InChI=1S/C24H17F6N3O2/c25-23(26,27)10-1-11-35-18-8-6-17(7-9-18)22(24(28,29)30)12-19(20(14-32)21(34)33-22)16-4-2-15(13-31)3-5-16/h2-9H,1,10-12H2,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 265n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201303
PNG
(US9187424, 67 | US9187424, 74)
Show SMILES Fc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C23H17F7N2O2/c24-16-6-2-14(3-7-16)18-12-21(23(28,29)30,32-20(33)19(18)13-31)15-4-8-17(9-5-15)34-11-1-10-22(25,26)27/h2-9H,1,10-12H2,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 253n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM201304
PNG
(US9187424, 68)
Show SMILES FC(F)(F)CCCOc1ccc(cc1)C1(CC(=C(C#N)C(=O)N1)c1cccc(Cl)c1)C(F)(F)F
Show InChI InChI=1S/C23H17ClF6N2O2/c24-16-4-1-3-14(11-16)18-12-21(23(28,29)30,32-20(33)19(18)13-31)15-5-7-17(8-6-15)34-10-2-9-22(25,26)27/h1,3-8,11H,2,9-10,12H2,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.28E+3n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 634 total )  |  Next  |  Last  >>
Jump to: