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Compile Data Set for Download or QSAR

Found 788 hits of ph data with Target = 'Apelin receptor'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Apelin receptor


(Homo sapiens)
BDBM269507
PNG
(N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridiny...)
Show SMILES COc1cccc(n1)-c1nnc(NS(C)(=O)=O)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C17H19N5O5S/c1-25-12-8-6-9-13(26-2)15(12)22-16(11-7-5-10-14(18-11)27-3)19-20-17(22)21-28(4,23)24/h5-10H,1-4H3,(H,20,21)
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n/an/an/an/a 220n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269508
PNG
(US10058550, Example 27.0 | US10058550, Example 549...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O6S/c1-15-13-26-23(27-14-15)22(38-6)16(2)39(33,34)31-25-30-29-24(17-9-7-12-20(28-17)37-5)32(25)21-18(35-3)10-8-11-19(21)36-4/h7-14,16,22H,1-6H3,(H,30,31)/t16-,22-/m0/s1
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n/an/an/an/a 0.190n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269508
PNG
(US10058550, Example 27.0 | US10058550, Example 549...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O6S/c1-15-13-26-23(27-14-15)22(38-6)16(2)39(33,34)31-25-30-29-24(17-9-7-12-20(28-17)37-5)32(25)21-18(35-3)10-8-11-19(21)36-4/h7-14,16,22H,1-6H3,(H,30,31)/t16-,22-/m0/s1
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n/an/an/an/a 0.190n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269510
PNG
(US10058550, Example 28.0 | yl)-1-methoxy-1-(5-meth...)
Show SMILES CO[C@H]([C@@H](C)S(=O)(=O)Nc1nnc(-c2cncc(C)c2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O5S/c1-15-10-18(14-26-11-15)24-29-30-25(32(24)21-19(35-4)8-7-9-20(21)36-5)31-38(33,34)17(3)22(37-6)23-27-12-16(2)13-28-23/h7-14,17,22H,1-6H3,(H,30,31)/t17-,22-/m1/s1
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n/an/an/an/a 62n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269511
PNG
(US10058550, Example 543.0 | yl)-1-methoxy-1-(5-met...)
Show SMILES CO[C@H]([C@@H](C)S(=O)(=O)Nc1nnc(-c2cncc(C)c2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O5S/c1-15-10-18(14-26-11-15)24-29-30-25(32(24)21-19(35-4)8-7-9-20(21)36-5)31-38(33,34)17(3)22(37-6)23-27-12-16(2)13-28-23/h7-14,17,22H,1-6H3,(H,30,31)/t17-,22-/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269512
PNG
(N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridiny...)
Show SMILES CCS(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C18H21N5O5S/c1-5-29(24,25)22-18-21-20-17(12-8-6-11-15(19-12)28-4)23(18)16-13(26-2)9-7-10-14(16)27-3/h6-11H,5H2,1-4H3,(H,21,22)
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269513
PNG
(N-(4-(2,6-dimethoxyphenyl)-5-(6-methyl-2-pyridinyl...)
Show SMILES CCS(=O)(=O)Nc1nnc(-c2cccc(C)n2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C18H21N5O4S/c1-5-28(24,25)22-18-21-20-17(13-9-6-8-12(2)19-13)23(18)16-14(26-3)10-7-11-15(16)27-4/h6-11H,5H2,1-4H3,(H,21,22)
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n/an/an/an/a 830n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269514
PNG
((2R)-1-(5-fluoro-2-pyrimidinyl)-N-(4-(2-methoxyphe...)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@H](C)Cc2ncc(F)cn2)n1-c1ccccc1OC
Show InChI InChI=1S/C22H22FN7O4S/c1-14(11-19-24-12-15(23)13-25-19)35(31,32)29-22-28-27-21(16-7-6-10-20(26-16)34-3)30(22)17-8-4-5-9-18(17)33-2/h4-10,12-14H,11H2,1-3H3,(H,28,29)/t14-/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269515
PNG
((2R)-N-(4-(3,5-dimethyl-4-isoxazolyl)-5-(6-methoxy...)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@H](C)Cc2ncc(F)cn2)n1-c1c(C)noc1C
Show InChI InChI=1S/C20H21FN8O4S/c1-11(8-16-22-9-14(21)10-23-16)34(30,31)28-20-26-25-19(15-6-5-7-17(24-15)32-4)29(20)18-12(2)27-33-13(18)3/h5-7,9-11H,8H2,1-4H3,(H,26,28)/t11-/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269516
PNG
((1R,2S)-1-methoxy-N-(5-(6-methoxy-2-pyridinyl)-4-(...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1cccnc1)c1ncc(C)cn1
Show InChI InChI=1S/C22H24N8O4S/c1-14-11-24-20(25-12-14)19(34-4)15(2)35(31,32)29-22-28-27-21(17-8-5-9-18(26-17)33-3)30(22)16-7-6-10-23-13-16/h5-13,15,19H,1-4H3,(H,28,29)/t15-,19-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269517
PNG
((1R,2S)-1-methoxy-N-(5-(6-methoxy-2-pyridinyl)-4-p...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1ccccc1)c1ncc(C)cn1
Show InChI InChI=1S/C23H25N7O4S/c1-15-13-24-21(25-14-15)20(34-4)16(2)35(31,32)29-23-28-27-22(18-11-8-12-19(26-18)33-3)30(23)17-9-6-5-7-10-17/h5-14,16,20H,1-4H3,(H,28,29)/t16-,20-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269518
PNG
((1R,2S)-N-(4-(4,6-dimethoxy-5-pyrimidinyl)-5-(6-me...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)ncnc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C23H27N9O6S/c1-13-10-24-19(25-11-13)18(36-4)14(2)39(33,34)31-23-30-29-20(15-8-7-9-16(28-15)35-3)32(23)17-21(37-5)26-12-27-22(17)38-6/h7-12,14,18H,1-6H3,(H,30,31)/t14-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269519
PNG
((1R,2S)-N-(4-(2,6-bis ([2H3])methyloxy)phenyl)-5-(...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O6S/c1-15-13-26-23(27-14-15)22(38-6)16(2)39(33,34)31-25-30-29-24(17-9-7-12-20(28-17)37-5)32(25)21-18(35-3)10-8-11-19(21)36-4/h7-14,16,22H,1-6H3,(H,30,31)/t16-,22-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269520
PNG
((1R,2S)-N-(4-(2,6-bis([2H3])methyloxy)phenyl)-5-(6...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O6S/c1-15-13-26-23(27-14-15)22(38-6)16(2)39(33,34)31-25-30-29-24(17-9-7-12-20(28-17)37-5)32(25)21-18(35-3)10-8-11-19(21)36-4/h7-14,16,22H,1-6H3,(H,30,31)/t16-,22-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269521
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-([2H3]meth...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O6S/c1-15-13-26-23(27-14-15)22(38-6)16(2)39(33,34)31-25-30-29-24(17-9-7-12-20(28-17)37-5)32(25)21-18(35-3)10-8-11-19(21)36-4/h7-14,16,22H,1-6H3,(H,30,31)/t16-,22-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269522
PNG
((1R,2S)-N-(4-(3,5-bis(trifluoromethyl)phenyl)-5-(6...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ncc(C)cn1
Show InChI InChI=1S/C25H23F6N7O4S/c1-13-11-32-21(33-12-13)20(42-4)14(2)43(39,40)37-23-36-35-22(18-6-5-7-19(34-18)41-3)38(23)17-9-15(24(26,27)28)8-16(10-17)25(29,30)31/h5-12,14,20H,1-4H3,(H,36,37)/t14-,20-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269523
PNG
((1R,2S)-1-methoxy-N-(4-(2-methoxy-5-methylphenyl)-...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1cc(C)ccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O5S/c1-15-10-11-20(35-4)19(12-15)32-24(18-8-7-9-21(28-18)36-5)29-30-25(32)31-38(33,34)17(3)22(37-6)23-26-13-16(2)14-27-23/h7-14,17,22H,1-6H3,(H,30,31)/t17-,22-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269524
PNG
((1R,2S)-N-(4-(2,6-bis(difluoromethoxy)phenyl)-5-(6...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC(F)F)cccc1OC(F)F)c1ncc(C)cn1
Show InChI InChI=1S/C25H25F4N7O6S/c1-13-11-30-21(31-12-13)20(40-4)14(2)43(37,38)35-25-34-33-22(15-7-5-10-18(32-15)39-3)36(25)19-16(41-23(26)27)8-6-9-17(19)42-24(28)29/h5-12,14,20,23-24H,1-4H3,(H,34,35)/t14-,20-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269525
PNG
((1R,2S)-1-methoxy-N-(5-(6-methoxy-2-pyridinyl)-4-(...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1ccncc1)c1ncc(C)cn1
Show InChI InChI=1S/C22H24N8O4S/c1-14-12-24-20(25-13-14)19(34-4)15(2)35(31,32)29-22-28-27-21(17-6-5-7-18(26-17)33-3)30(22)16-8-10-23-11-9-16/h5-13,15,19H,1-4H3,(H,28,29)/t15-,19-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269526
PNG
((1R,2S)-N-(4-(2-ethoxy-6-methoxyphenyl)-5-(6-metho...)
Show SMILES CCOc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(C)cn2)nnc1-c1cccc(OC)n1
Show InChI InChI=1S/C26H31N7O6S/c1-7-39-20-12-9-11-19(36-4)22(20)33-25(18-10-8-13-21(29-18)37-5)30-31-26(33)32-40(34,35)17(3)23(38-6)24-27-14-16(2)15-28-24/h8-15,17,23H,7H2,1-6H3,(H,31,32)/t17-,23-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269568
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)...)
Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](O)c2ncc(F)cn2)nnc1-c1cccnc1
Show InChI InChI=1S/C22H22FN7O5S/c1-13(19(31)20-25-11-15(23)12-26-20)36(32,33)29-22-28-27-21(14-6-5-9-24-10-14)30(22)18-16(34-2)7-4-8-17(18)35-3/h4-13,19,31H,1-3H3,(H,28,29)/t13-,19-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269569
PNG
((2R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyr...)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@H](C)C(=O)N2CCCC2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C23H28N6O6S/c1-15(22(30)28-13-5-6-14-28)36(31,32)27-23-26-25-21(16-9-7-12-19(24-16)35-4)29(23)20-17(33-2)10-8-11-18(20)34-3/h7-12,15H,5-6,13-14H2,1-4H3,(H,26,27)/t15-/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269570
PNG
((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(2-methoxy-4-...)
Show SMILES COc1cc(ccn1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(C)cn2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C25H29N7O5S/c1-15-13-27-23(28-14-15)16(2)17(3)38(33,34)31-25-30-29-24(18-10-11-26-21(12-18)37-6)32(25)22-19(35-4)8-7-9-20(22)36-5/h7-14,16-17H,1-6H3,(H,30,31)/t16-,17-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269571
PNG
((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(2-methyl-4-p...)
Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(C)cn2)nnc1-c1ccnc(C)c1
Show InChI InChI=1S/C25H29N7O4S/c1-15-13-27-23(28-14-15)17(3)18(4)37(33,34)31-25-30-29-24(19-10-11-26-16(2)12-19)32(25)22-20(35-5)8-7-9-21(22)36-6/h7-14,17-18H,1-6H3,(H,30,31)/t17-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269572
PNG
((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methoxy-3-...)
Show SMILES COc1cncc(c1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(C)cn2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C25H29N7O5S/c1-15-11-27-23(28-12-15)16(2)17(3)38(33,34)31-25-30-29-24(18-10-19(35-4)14-26-13-18)32(25)22-20(36-5)8-7-9-21(22)37-6/h7-14,16-17H,1-6H3,(H,30,31)/t16-,17-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269573
PNG
((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methyl-2-p...)
Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(C)cn2)nnc1-c1cccc(C)n1
Show InChI InChI=1S/C25H29N7O4S/c1-15-13-26-23(27-14-15)17(3)18(4)37(33,34)31-25-30-29-24(19-10-7-9-16(2)28-19)32(25)22-20(35-5)11-8-12-21(22)36-6/h7-14,17-18H,1-6H3,(H,30,31)/t17-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269574
PNG
((1R,2S)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(C)n2)n1-c1c(OC)cccc1OC)c1ncc(Cl)cn1
Show InChI InChI=1S/C24H26ClN7O5S/c1-14-8-6-9-17(28-14)23-29-30-24(32(23)20-18(35-3)10-7-11-19(20)36-4)31-38(33,34)15(2)21(37-5)22-26-12-16(25)13-27-22/h6-13,15,21H,1-5H3,(H,30,31)/t15-,21-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269575
PNG
((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Show SMILES CO[C@H]([C@@H](C)S(=O)(=O)Nc1nnc(-c2cccc(C)n2)n1-c1c(OC)cccc1OC)c1ncc(Cl)cn1
Show InChI InChI=1S/C24H26ClN7O5S/c1-14-8-6-9-17(28-14)23-29-30-24(32(23)20-18(35-3)10-7-11-19(20)36-4)31-38(33,34)15(2)21(37-5)22-26-12-16(25)13-27-22/h6-13,15,21H,1-5H3,(H,30,31)/t15-,21-/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269576
PNG
((1R,2S)-N-(4-(4,6-dimethoxy-5-pyrimidinyl)-5-(6-me...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(C)n2)n1-c1c(OC)ncnc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C23H27N9O5S/c1-13-10-24-19(25-11-13)18(35-4)15(3)38(33,34)31-23-30-29-20(16-9-7-8-14(2)28-16)32(23)17-21(36-5)26-12-27-22(17)37-6/h7-12,15,18H,1-6H3,(H,30,31)/t15-,18-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269577
PNG
((1S,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)nnc1-c1cncc(C)c1
Show InChI InChI=1S/C27H33N7O5S/c1-16(2)39-24(25-29-13-18(4)14-30-25)19(5)40(35,36)33-27-32-31-26(20-11-17(3)12-28-15-20)34(27)23-21(37-6)9-8-10-22(23)38-7/h8-16,19,24H,1-7H3,(H,32,33)/t19-,24+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269578
PNG
((1R,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@H](C)[C@H](OC(C)C)c2ncc(C)cn2)nnc1-c1cncc(C)c1
Show InChI InChI=1S/C27H33N7O5S/c1-16(2)39-24(25-29-13-18(4)14-30-25)19(5)40(35,36)33-27-32-31-26(20-11-17(3)12-28-15-20)34(27)23-21(37-6)9-8-10-22(23)38-7/h8-16,19,24H,1-7H3,(H,32,33)/t19-,24+/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269579
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](OC(C)C)c2ncc(C)cn2)nnc1-c1cncc(C)c1
Show InChI InChI=1S/C27H33N7O5S/c1-16(2)39-24(25-29-13-18(4)14-30-25)19(5)40(35,36)33-27-32-31-26(20-11-17(3)12-28-15-20)34(27)23-21(37-6)9-8-10-22(23)38-7/h8-16,19,24H,1-7H3,(H,32,33)/t19-,24-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269580
PNG
((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)nnc1-c1cncc(C)c1
Show InChI InChI=1S/C27H33N7O5S/c1-16(2)39-24(25-29-13-18(4)14-30-25)19(5)40(35,36)33-27-32-31-26(20-11-17(3)12-28-15-20)34(27)23-21(37-6)9-8-10-22(23)38-7/h8-16,19,24H,1-7H3,(H,32,33)/t19-,24-/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269581
PNG
((1S,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C27H33N7O6S/c1-16(2)40-24(25-28-14-17(3)15-29-25)18(4)41(35,36)33-27-32-31-26(19-10-8-13-22(30-19)39-7)34(27)23-20(37-5)11-9-12-21(23)38-6/h8-16,18,24H,1-7H3,(H,32,33)/t18-,24+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269582
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](OC(C)C)c2ncc(C)cn2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C27H33N7O6S/c1-16(2)40-24(25-28-14-17(3)15-29-25)18(4)41(35,36)33-27-32-31-26(19-10-8-13-22(30-19)39-7)34(27)23-20(37-5)11-9-12-21(23)38-6/h8-16,18,24H,1-7H3,(H,32,33)/t18-,24-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269583
PNG
((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@H](C)[C@@H](OC(C)C)c2ncc(C)cn2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C27H33N7O6S/c1-16(2)40-24(25-28-14-17(3)15-29-25)18(4)41(35,36)33-27-32-31-26(19-10-8-13-22(30-19)39-7)34(27)23-20(37-5)11-9-12-21(23)38-6/h8-16,18,24H,1-7H3,(H,32,33)/t18-,24-/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269584
PNG
((1R,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@H](C)[C@H](OC(C)C)c2ncc(C)cn2)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C27H33N7O6S/c1-16(2)40-24(25-28-14-17(3)15-29-25)18(4)41(35,36)33-27-32-31-26(19-10-8-13-22(30-19)39-7)34(27)23-20(37-5)11-9-12-21(23)38-6/h8-16,18,24H,1-7H3,(H,32,33)/t18-,24+/m1/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269585
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methyl-2-p...)
Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](O)c2ncc(C)cn2)nnc1-c1cccc(C)n1
Show InChI InChI=1S/C24H27N7O5S/c1-14-12-25-22(26-13-14)21(32)16(3)37(33,34)30-24-29-28-23(17-9-6-8-15(2)27-17)31(24)20-18(35-4)10-7-11-19(20)36-5/h6-13,16,21,32H,1-5H3,(H,29,30)/t16-,21-/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269586
PNG
(N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridiny...)
Show SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)C(C)C)n1-c1c(OC)cccc1OC
Show InChI InChI=1S/C19H23N5O5S/c1-12(2)30(25,26)23-19-22-21-18(13-8-6-11-16(20-13)29-5)24(19)17-14(27-3)9-7-10-15(17)28-4/h6-12H,1-5H3,(H,22,23)
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n/an/an/an/a 110n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269587
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(2-methoxy-4-...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2ccnc(OC)c2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O6S/c1-15-13-27-23(28-14-15)22(38-6)16(2)39(33,34)31-25-30-29-24(17-10-11-26-20(12-17)37-5)32(25)21-18(35-3)8-7-9-19(21)36-4/h7-14,16,22H,1-6H3,(H,30,31)/t16-,22-/m0/s1
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n/an/an/an/a 7n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269588
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(4-pyridinyl)...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2ccncc2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C24H27N7O5S/c1-15-13-26-22(27-14-15)21(36-5)16(2)37(32,33)30-24-29-28-23(17-9-11-25-12-10-17)31(24)20-18(34-3)7-6-8-19(20)35-4/h6-14,16,21H,1-5H3,(H,29,30)/t16-,21-/m0/s1
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n/an/an/an/a 18n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269589
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methyl-2-p...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(C)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O5S/c1-15-13-26-23(27-14-15)22(37-6)17(3)38(33,34)31-25-30-29-24(18-10-7-9-16(2)28-18)32(25)21-19(35-4)11-8-12-20(21)36-5/h7-14,17,22H,1-6H3,(H,30,31)/t17-,22-/m0/s1
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n/an/an/an/a 0.510n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269590
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(2-methyl-4-p...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2ccnc(C)c2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O5S/c1-15-13-27-23(28-14-15)22(37-6)17(3)38(33,34)31-25-30-29-24(18-10-11-26-16(2)12-18)32(25)21-19(35-4)8-7-9-20(21)36-5/h7-14,17,22H,1-6H3,(H,30,31)/t17-,22-/m0/s1
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n/an/an/an/a 2.40n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269591
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methoxy-3-...)
Show SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cncc(OC)c2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O6S/c1-15-11-27-23(28-12-15)22(38-6)16(2)39(33,34)31-25-30-29-24(17-10-18(35-3)14-26-13-17)32(25)21-19(36-4)8-7-9-20(21)37-5/h7-14,16,22H,1-6H3,(H,30,31)/t16-,22-/m0/s1
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n/an/an/an/a 1.80n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269592
PNG
((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Show SMILES CCO[C@H]([C@@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C26H31N7O6S/c1-7-39-23(24-27-14-16(2)15-28-24)17(3)40(34,35)32-26-31-30-25(18-10-8-13-21(29-18)38-6)33(26)22-19(36-4)11-9-12-20(22)37-5/h8-15,17,23H,7H2,1-6H3,(H,31,32)/t17-,23-/m1/s1
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n/an/an/an/a 15n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269592
PNG
((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Show SMILES CCO[C@H]([C@@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C26H31N7O6S/c1-7-39-23(24-27-14-16(2)15-28-24)17(3)40(34,35)32-26-31-30-25(18-10-8-13-21(29-18)38-6)33(26)22-19(36-4)11-9-12-20(22)37-5/h8-15,17,23H,7H2,1-6H3,(H,31,32)/t17-,23-/m1/s1
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n/an/an/an/a 0.0900n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269594
PNG
((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)...)
Show SMILES CCO[C@H]([C@@H](C)S(=O)(=O)Nc1nnc(-c2cccnc2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O5S/c1-6-37-22(23-27-13-16(2)14-28-23)17(3)38(33,34)31-25-30-29-24(18-9-8-12-26-15-18)32(25)21-19(35-4)10-7-11-20(21)36-5/h7-15,17,22H,6H2,1-5H3,(H,30,31)/t17-,22-/m1/s1
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n/an/an/an/a 150n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269595
PNG
((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)...)
Show SMILES CCO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccnc2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C25H29N7O5S/c1-6-37-22(23-27-13-16(2)14-28-23)17(3)38(33,34)31-25-30-29-24(18-9-8-12-26-15-18)32(25)21-19(35-4)10-7-11-20(21)36-5/h7-15,17,22H,6H2,1-5H3,(H,30,31)/t17-,22-/m0/s1
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n/an/an/an/a 0.850n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269596
PNG
((1S,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Show SMILES CCO[C@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C26H31N7O6S/c1-7-39-23(24-27-14-16(2)15-28-24)17(3)40(34,35)32-26-31-30-25(18-10-8-13-21(29-18)38-6)33(26)22-19(36-4)11-9-12-20(22)37-5/h8-15,17,23H,7H2,1-6H3,(H,31,32)/t17-,23+/m0/s1
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AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
Apelin receptor


(Homo sapiens)
BDBM269596
PNG
((1S,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Show SMILES CCO[C@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1
Show InChI InChI=1S/C26H31N7O6S/c1-7-39-23(24-27-14-16(2)15-28-24)17(3)40(34,35)32-26-31-30-25(18-10-8-13-21(29-18)38-6)33(26)22-19(36-4)11-9-12-20(22)37-5/h8-15,17,23H,7H2,1-6H3,(H,31,32)/t17-,23+/m0/s1
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n/an/an/an/a 5.30n/an/a7.5n/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...


US Patent US10058550 (2018)

More data for this
Ligand-Target Pair
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