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Compile Data Set for Download or QSAR

Found 74 hits of ph data with Target = 'Beta-2 adrenergic receptor'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM27960
PNG
((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy...)
Show SMILES CC(C)N[C@@H](C)[C@@H](O)COc1ccc(C)c2CCCc12
Show InChI InChI=1S/C17H27NO2/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3/t13-,16-/m0/s1
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Article
PubMed
1 -50.9 3n/an/an/an/a7.422



Intervet Innovation GmbH



Assay Description
In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...


J Med Chem 52: 1773-7 (2009)


Article DOI: 10.1021/jm801211c
BindingDB Entry DOI: 10.7270/Q2H993HR
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25392
PNG
(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Show SMILES CC(C)NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
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Article
PubMed
136 -38.8n/an/an/an/an/a7.422



Monash University



Assay Description
The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...


J Med Chem 51: 6128-37 (2008)


Article DOI: 10.1021/jm800613s
BindingDB Entry DOI: 10.7270/Q26M3554
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM27959
PNG
(4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]ami...)
Show SMILES CC(CCc1ccc(O)cc1)NCC(O)c1ccc(O)cc1
Show InChI InChI=1S/C18H23NO3/c1-13(2-3-14-4-8-16(20)9-5-14)19-12-18(22)15-6-10-17(21)11-7-15/h4-11,13,18-22H,2-3,12H2,1H3
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PubMed
180 -38.1 330n/a 9.10n/an/a7.422



Intervet Innovation GmbH



Assay Description
In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...


J Med Chem 52: 1773-7 (2009)


Article DOI: 10.1021/jm801211c
BindingDB Entry DOI: 10.7270/Q2H993HR
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25398
PNG
(Bivalent derivative, 12e | N-[5-(2-{[6-({9-[(2R,3R...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCCCCCNCC(O)c3ccc(O)c(NC=O)c3)ncnc12
Show InChI InChI=1S/C25H35N7O7/c33-11-19-21(37)22(38)25(39-19)32-13-30-20-23(28-12-29-24(20)32)27-8-4-2-1-3-7-26-10-18(36)15-5-6-17(35)16(9-15)31-14-34/h5-6,9,12-14,18-19,21-22,25-26,33,35-38H,1-4,7-8,10-11H2,(H,31,34)(H,27,28,29)/t18?,19-,21-,22-,25-/m1/s1
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PubMed
311 -36.8n/an/an/an/an/a7.422



Monash University



Assay Description
The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...


J Med Chem 51: 6128-37 (2008)


Article DOI: 10.1021/jm800613s
BindingDB Entry DOI: 10.7270/Q26M3554
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM27955
PNG
((-)-Zilpaterol | (9R,10R)-9-hydroxy-10-(propan-2-y...)
Show SMILES CC(C)N[C@@H]1CCn2c3c(cccc3[nH]c2=O)[C@H]1O
Show InChI InChI=1S/C14H19N3O2/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19)/t11-,13-/m1/s1
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PubMed
320 -36.7 620n/a 8.70n/an/a7.422



Intervet Innovation GmbH



Assay Description
In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...


J Med Chem 52: 1773-7 (2009)


Article DOI: 10.1021/jm801211c
BindingDB Entry DOI: 10.7270/Q2H993HR
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25769
PNG
(4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxym...)
Show SMILES CC(C)(C)NCC(O)c1ccc(O)c(CO)c1
Show InChI InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3
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Article
PubMed
510 -35.6 980n/a 19n/an/a7.422



Intervet Innovation GmbH



Assay Description
In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...


J Med Chem 52: 1773-7 (2009)


Article DOI: 10.1021/jm801211c
BindingDB Entry DOI: 10.7270/Q2H993HR
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM27958
PNG
(1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)...)
Show SMILES CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
Show InChI InChI=1S/C12H18Cl2N2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3
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PubMed
570 -35.3 1.30E+3n/a 6.20n/an/a7.422



Intervet Innovation GmbH



Assay Description
In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...


J Med Chem 52: 1773-7 (2009)


Article DOI: 10.1021/jm801211c
BindingDB Entry DOI: 10.7270/Q2H993HR
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM27956
PNG
((rac)-Zilpaterol | 9-hydroxy-10-(propan-2-ylamino)...)
Show SMILES CC(C)NC1CCn2c3c(cccc3[nH]c2=O)C1O
Show InChI InChI=1S/C14H19N3O2/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19)
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PubMed
580 -35.2 1.10E+3n/a 13n/an/a7.422



Intervet Innovation GmbH



Assay Description
In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...


J Med Chem 52: 1773-7 (2009)


Article DOI: 10.1021/jm801211c
BindingDB Entry DOI: 10.7270/Q2H993HR
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25396
PNG
(Bivalent derivative, 12c | N-[5-(2-{[4-({9-[(2R,3R...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCCCNCC(O)c3ccc(O)c(NC=O)c3)ncnc12
Show InChI InChI=1S/C23H31N7O7/c31-9-17-19(35)20(36)23(37-17)30-11-28-18-21(26-10-27-22(18)30)25-6-2-1-5-24-8-16(34)13-3-4-15(33)14(7-13)29-12-32/h3-4,7,10-12,16-17,19-20,23-24,31,33-36H,1-2,5-6,8-9H2,(H,29,32)(H,25,26,27)/t16?,17-,19-,20-,23-/m1/s1
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PubMed
863 -34.3n/an/an/an/an/a7.422



Monash University



Assay Description
The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...


J Med Chem 51: 6128-37 (2008)


Article DOI: 10.1021/jm800613s
BindingDB Entry DOI: 10.7270/Q26M3554
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25399
PNG
(Bivalent derivative, 18 | N-[5-(1-{9-[(2R,3R,4S,5R...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCOCCOCCNCC(O)c3ccc(O)c(NC=O)c3)ncnc12
Show InChI InChI=1S/C25H35N7O9/c33-11-19-21(37)22(38)25(41-19)32-13-30-20-23(28-12-29-24(20)32)27-4-6-40-8-7-39-5-3-26-10-18(36)15-1-2-17(35)16(9-15)31-14-34/h1-2,9,12-14,18-19,21-22,25-26,33,35-38H,3-8,10-11H2,(H,31,34)(H,27,28,29)/t18?,19-,21-,22-,25-/m1/s1
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PubMed
2.30E+3 -31.9n/an/an/an/an/a7.422



Monash University



Assay Description
The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...


J Med Chem 51: 6128-37 (2008)


Article DOI: 10.1021/jm800613s
BindingDB Entry DOI: 10.7270/Q26M3554
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25397
PNG
((2R,3R,4S,5R)-2-{6-[(4-{[2-(3-amino-4-hydroxypheny...)
Show SMILES Nc1cc(ccc1O)C(O)CNCCCCNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C22H31N7O6/c23-13-7-12(3-4-14(13)31)15(32)8-24-5-1-2-6-25-20-17-21(27-10-26-20)29(11-28-17)22-19(34)18(33)16(9-30)35-22/h3-4,7,10-11,15-16,18-19,22,24,30-34H,1-2,5-6,8-9,23H2,(H,25,26,27)/t15?,16-,18-,19-,22-/m1/s1
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PubMed
4.31E+3 -30.3n/an/an/an/an/a7.422



Monash University



Assay Description
The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...


J Med Chem 51: 6128-37 (2008)


Article DOI: 10.1021/jm800613s
BindingDB Entry DOI: 10.7270/Q26M3554
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25395
PNG
((2R,3R,4S,5R)-2-{6-[(2-{[2-(3-amino-4-hydroxypheny...)
Show SMILES Nc1cc(ccc1O)C(O)CNCCNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C20H27N7O6/c21-11-5-10(1-2-12(11)29)13(30)6-22-3-4-23-18-15-19(25-8-24-18)27(9-26-15)20-17(32)16(31)14(7-28)33-20/h1-2,5,8-9,13-14,16-17,20,22,28-32H,3-4,6-7,21H2,(H,23,24,25)/t13?,14-,16-,17-,20-/m1/s1
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>1.00E+4>-28.3n/an/an/an/an/a7.422



Monash University



Assay Description
The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...


J Med Chem 51: 6128-37 (2008)


Article DOI: 10.1021/jm800613s
BindingDB Entry DOI: 10.7270/Q26M3554
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25394
PNG
(Bivalent derivative, 12a | N-[5-(2-{[2-({9-[(2R,3R...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCNCC(O)c3ccc(O)c(NC=O)c3)ncnc12
Show InChI InChI=1S/C21H27N7O7/c29-7-15-17(33)18(34)21(35-15)28-9-26-16-19(24-8-25-20(16)28)23-4-3-22-6-14(32)11-1-2-13(31)12(5-11)27-10-30/h1-2,5,8-10,14-15,17-18,21-22,29,31-34H,3-4,6-7H2,(H,27,30)(H,23,24,25)/t14?,15-,17-,18-,21-/m1/s1
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PubMed
>1.00E+4>-28.3n/an/an/an/an/a7.422



Monash University



Assay Description
The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...


J Med Chem 51: 6128-37 (2008)


Article DOI: 10.1021/jm800613s
BindingDB Entry DOI: 10.7270/Q26M3554
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM86556
PNG
(Azanium analog, 28)
Show SMILES C([NH2+]Cc1cccc2cccnc12)[C@@H]1COc2ccccc2O1
Show InChI InChI=1S/C19H18N2O2/c1-2-9-18-17(8-1)22-13-16(23-18)12-20-11-15-6-3-5-14-7-4-10-21-19(14)15/h1-10,16,20H,11-13H2/p+1/t16-/m1/s1
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Article
PubMed
>1.00E+4>-28.3n/an/an/an/an/a7.422



University of California San Francisco



Assay Description
Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...


Nat Chem Biol 7: 769-78 (2011)


Article DOI: 10.1038/nchembio.662
BindingDB Entry DOI: 10.7270/Q2TM78P6
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM86550
PNG
(Piperidin-1-ium analog, 2)
Show SMILES COC(=O)c1occc1C[NH+]1CCC(CC1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H22N2O3/c1-24-20(23)19-15(8-11-25-19)13-22-9-6-14(7-10-22)17-12-21-18-5-3-2-4-16(17)18/h2-5,8,11-12,14,21H,6-7,9-10,13H2,1H3/p+1
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>1.00E+4>-28.3n/an/an/an/an/a7.422



University of California San Francisco



Assay Description
Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...


Nat Chem Biol 7: 769-78 (2011)


Article DOI: 10.1038/nchembio.662
BindingDB Entry DOI: 10.7270/Q2TM78P6
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM86551
PNG
(Azanium analog, 3)
Show SMILES CC(CO)(CO)[NH2+]Cc1ccc(o1)-c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C15H17Cl2NO3/c1-15(8-19,9-20)18-7-11-3-5-14(21-11)12-6-10(16)2-4-13(12)17/h2-6,18-20H,7-9H2,1H3/p+1
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>1.00E+4>-28.3n/an/an/an/an/a7.422



University of California San Francisco



Assay Description
Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...


Nat Chem Biol 7: 769-78 (2011)


Article DOI: 10.1038/nchembio.662
BindingDB Entry DOI: 10.7270/Q2TM78P6
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM86552
PNG
(Piperidin-1-ium analog, 4)
Show SMILES O[C@@H](C[NH+]1CCN(CC1)c1nsc2ccccc12)c1cccs1
Show InChI InChI=1S/C17H19N3OS2/c21-14(16-6-3-11-22-16)12-19-7-9-20(10-8-19)17-13-4-1-2-5-15(13)23-18-17/h1-6,11,14,21H,7-10,12H2/p+1/t14-/m0/s1
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>1.00E+4>-28.3n/an/an/an/an/a7.422



University of California San Francisco



Assay Description
Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...


Nat Chem Biol 7: 769-78 (2011)


Article DOI: 10.1038/nchembio.662
BindingDB Entry DOI: 10.7270/Q2TM78P6
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM86553
PNG
(Piperidin-1-ium analog, 5)
Show SMILES OCCN1CC[NH+](CCOc2ccccc2-c2ccccc2)CC1
Show InChI InChI=1S/C20H26N2O2/c23-16-14-21-10-12-22(13-11-21)15-17-24-20-9-5-4-8-19(20)18-6-2-1-3-7-18/h1-9,23H,10-17H2/p+1
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>1.00E+4>-28.3n/an/an/an/an/a7.422



University of California San Francisco



Assay Description
Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...


Nat Chem Biol 7: 769-78 (2011)


Article DOI: 10.1038/nchembio.662
BindingDB Entry DOI: 10.7270/Q2TM78P6
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM86554
PNG
(Azanium analog, 6)
Show SMILES Fc1ccc(cc1)-c1ccc(C[NH2+]Cc2cccnc2-n2cccn2)o1
Show InChI InChI=1S/C20H17FN4O/c21-17-6-4-15(5-7-17)19-9-8-18(26-19)14-22-13-16-3-1-10-23-20(16)25-12-2-11-24-25/h1-12,22H,13-14H2/p+1
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>1.00E+4>-28.3n/an/an/an/an/a7.422



University of California San Francisco



Assay Description
Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...


Nat Chem Biol 7: 769-78 (2011)


Article DOI: 10.1038/nchembio.662
BindingDB Entry DOI: 10.7270/Q2TM78P6
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM86555
PNG
(Piperazin-1-ium analog, 7)
Show SMILES Cc1cccc(c1)N1CC[NH+](C[C@@H](O)c2ccccc2F)CC1
Show InChI InChI=1S/C19H23FN2O/c1-15-5-4-6-16(13-15)22-11-9-21(10-12-22)14-19(23)17-7-2-3-8-18(17)20/h2-8,13,19,23H,9-12,14H2,1H3/p+1/t19-/m1/s1
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>1.00E+4>-28.3n/an/an/an/an/a7.422



University of California San Francisco



Assay Description
Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...


Nat Chem Biol 7: 769-78 (2011)


Article DOI: 10.1038/nchembio.662
BindingDB Entry DOI: 10.7270/Q2TM78P6
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM175238
PNG
(US9115082, 7)
Show SMILES OC(CNCC(=O)N1CCCC1C#N)COc1ccccc1
Show InChI InChI=1S/C16H21N3O3/c17-9-13-5-4-8-19(13)16(21)11-18-10-14(20)12-22-15-6-2-1-3-7-15/h1-3,6-7,13-14,18,20H,4-5,8,10-12H2
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2.20E+4n/a 3.20E+4n/an/an/an/a7.4n/a



TBA

US Patent


Assay Description
Human recombinant adrenergic β2 receptors expressed in CHO cells are used in modified Tris-HCl buffer pH 7.4. A 50 aliquot is incubated with 0.2...


US Patent US9115082 (2015)


BindingDB Entry DOI: 10.7270/Q2JS9P7B
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM27957
PNG
((+)-Zilpaterol | (9S,10S)-9-hydroxy-10-(propan-2-y...)
Show SMILES CC(C)N[C@H]1CCn2c3c(cccc3[nH]c2=O)[C@@H]1O
Show InChI InChI=1S/C14H19N3O2/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19)/t11-,13-/m0/s1
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n/an/an/an/a 6.90E+3n/an/a7.422



Intervet Innovation GmbH



Assay Description
In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...


J Med Chem 52: 1773-7 (2009)


Article DOI: 10.1021/jm801211c
BindingDB Entry DOI: 10.7270/Q2H993HR
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213098
PNG
((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Show SMILES C[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17+/m1/s1
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n/an/an/a 347n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213106
PNG
((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Show SMILES C[C@@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17-/m0/s1
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US Patent
n/an/an/a 3.72E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213103
PNG
((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Show SMILES C[C@H](Cc1ccc(O)cc1)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17-/m1/s1
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US Patent
n/an/an/a 1.02E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213114
PNG
((S,S)-(+)-fenoterol | CHEMBL389390 | US10617654, C...)
Show SMILES C[C@@H](Cc1ccc(O)cc1)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17+/m0/s1
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US Patent
n/an/an/a 2.75E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213099
PNG
((R,R)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Show SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
Show InChI InChI=1S/C18H23NO4/c1-12(7-13-3-5-17(23-2)6-4-13)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-6,8-10,12,18-22H,7,11H2,1-2H3/t12-,18+/m1/s1
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n/an/an/a 479n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213120
PNG
((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Show SMILES COc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
Show InChI InChI=1S/C18H23NO4/c1-12(7-13-3-5-17(23-2)6-4-13)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-6,8-10,12,18-22H,7,11H2,1-2H3/t12-,18-/m0/s1
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US Patent
n/an/an/a 1.95E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206769
PNG
( (S,R)-2 | US9492405, (S,R)-2)
Show SMILES COc1cccc(C[C@@H](C)NC[C@@H](O)c2cc(O)cc(O)c2)c1
Show InChI InChI=1S/C18H23NO4/c1-12(6-13-4-3-5-17(7-13)23-2)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-5,7-10,12,18-22H,6,11H2,1-2H3/t12-,18-/m1/s1
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n/an/an/a 5.25E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206770
PNG
( (S,S)- 2 | US9492405, (S,S)-2)
Show SMILES COc1cccc(C[C@H](C)NC[C@@H](O)c2cc(O)cc(O)c2)c1
Show InChI InChI=1S/C18H23NO4/c1-12(6-13-4-3-5-17(7-13)23-2)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-5,7-10,12,18-22H,6,11H2,1-2H3/t12-,18+/m0/s1
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n/an/an/a 1.58E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213108
PNG
((R,R)-(-)-5-{2-[2-(4-aminophenyl)-1-methylethylami...)
Show SMILES C[C@H](Cc1ccccc1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO3/c1-12(7-13-5-3-2-4-6-13)18-11-17(21)14-8-15(19)10-16(20)9-14/h2-6,8-10,12,17-21H,7,11H2,1H3/t12-,17+/m1/s1
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n/an/an/a 2.95E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213112
PNG
((R,S)-(-)-5-{2-[2-(4-aminophenyl)-1-methylethylami...)
Show SMILES C[C@@H](Cc1ccccc1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO3/c1-12(7-13-5-3-2-4-6-13)18-11-17(21)14-8-15(19)10-16(20)9-14/h2-6,8-10,12,17-21H,7,11H2,1H3/t12-,17-/m0/s1
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n/an/an/a 7.94E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213116
PNG
((S,R)-(+)-5-{2-[2-(4-aminophenyl)-1-methylethylami...)
Show SMILES C[C@H](Cc1ccccc1)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO3/c1-12(7-13-5-3-2-4-6-13)18-11-17(21)14-8-15(19)10-16(20)9-14/h2-6,8-10,12,17-21H,7,11H2,1H3/t12-,17-/m1/s1
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n/an/an/a 2.29E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213118
PNG
((S,S)-(+)-5-{2-[2-(4-aminophenyl)-1-methylethylami...)
Show SMILES C[C@@H](Cc1ccccc1)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO3/c1-12(7-13-5-3-2-4-6-13)18-11-17(21)14-8-15(19)10-16(20)9-14/h2-6,8-10,12,17-21H,7,11H2,1H3/t12-,17+/m0/s1
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n/an/an/a 2.88E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206771
PNG
((R,R)-4 | US9492405, (R,R)-4)
Show SMILES C[C@H](Cc1cccc(N)c1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H22N2O3/c1-11(5-12-3-2-4-14(18)6-12)19-10-17(22)13-7-15(20)9-16(21)8-13/h2-4,6-9,11,17,19-22H,5,10,18H2,1H3/t11-,17+/m1/s1
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n/an/an/a 1.86E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206772
PNG
((R,S)-4 | US9492405, (R,S)-4)
Show SMILES C[C@@H](Cc1cccc(N)c1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H22N2O3/c1-11(5-12-3-2-4-14(18)6-12)19-10-17(22)13-7-15(20)9-16(21)8-13/h2-4,6-9,11,17,19-22H,5,10,18H2,1H3/t11-,17-/m0/s1
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n/an/an/a 6.03E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206773
PNG
((S,R)- 4 | US9492405, (S,R)-4)
Show SMILES C[C@H](Cc1cccc(N)c1)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H22N2O3/c1-11(5-12-3-2-4-14(18)6-12)19-10-17(22)13-7-15(20)9-16(21)8-13/h2-4,6-9,11,17,19-22H,5,10,18H2,1H3/t11-,17-/m1/s1
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n/an/an/a 3.09E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206774
PNG
((S,S)- 4 | US9492405, (S,S)-4)
Show SMILES C[C@@H](Cc1cccc(N)c1)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H22N2O3/c1-11(5-12-3-2-4-14(18)6-12)19-10-17(22)13-7-15(20)9-16(21)8-13/h2-4,6-9,11,17,19-22H,5,10,18H2,1H3/t11-,17+/m0/s1
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UniChem
US Patent
n/an/an/a 2.88E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213115
PNG
((R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21+/m1/s1
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US Patent
n/an/an/a 240n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213110
PNG
((R,S)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21-/m0/s1
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US Patent
n/an/an/a 339n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213096
PNG
((S,R)-(+)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@H](Cc1cccc2ccccc12)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21-/m1/s1
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US Patent
n/an/an/a 1.78E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213101
PNG
((S,S)-(+)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@@H](Cc1cccc2ccccc12)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21+/m0/s1
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US Patent
n/an/an/a 2.51E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206775
PNG
((R,R)- 6 | US9492405, (R,R)-6)
Show SMILES CCCCC[C@@H](C)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C15H25NO3/c1-3-4-5-6-11(2)16-10-15(19)12-7-13(17)9-14(18)8-12/h7-9,11,15-19H,3-6,10H2,1-2H3/t11-,15+/m1/s1
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US Patent
n/an/an/a 9.33E+3n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206776
PNG
((R,S)-6 | US9492405, (R,S)-6)
Show SMILES CCCCC[C@H](C)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C15H25NO3/c1-3-4-5-6-11(2)16-10-15(19)12-7-13(17)9-14(18)8-12/h7-9,11,15-19H,3-6,10H2,1-2H3/t11-,15-/m0/s1
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US Patent
n/an/an/a 3.16E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206777
PNG
((S,R)- 6 | US9492405, (S,R)-6)
Show SMILES CCCCC[C@@H](C)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C15H25NO3/c1-3-4-5-6-11(2)16-10-15(19)12-7-13(17)9-14(18)8-12/h7-9,11,15-19H,3-6,10H2,1-2H3/t11-,15-/m1/s1
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US Patent
n/an/an/a 1.00E+5n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM206778
PNG
((S,S)-6 | US9492405, (S,S)-6)
Show SMILES CCCCC[C@H](C)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C15H25NO3/c1-3-4-5-6-11(2)16-10-15(19)12-7-13(17)9-14(18)8-12/h7-9,11,15-19H,3-6,10H2,1-2H3/t11-,15+/m0/s1
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US Patent
n/an/an/a 5.62E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213119
PNG
((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Show SMILES O[C@@H](CNCCc1ccccc1)c1cc(O)cc(O)c1
Show InChI InChI=1S/C16H19NO3/c18-14-8-13(9-15(19)10-14)16(20)11-17-7-6-12-4-2-1-3-5-12/h1-5,8-10,16-20H,6-7,11H2/t16-/m0/s1
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US Patent
n/an/an/a 1.05E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213121
PNG
((S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Show SMILES O[C@H](CNCCc1ccccc1)c1cc(O)cc(O)c1
Show InChI InChI=1S/C16H19NO3/c18-14-8-13(9-15(19)10-14)16(20)11-17-7-6-12-4-2-1-3-5-12/h1-5,8-10,16-20H,6-7,11H2/t16-/m1/s1
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US Patent
n/an/an/a 2.04E+4n/an/an/a7.7n/a



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213115
PNG
((R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21+/m1/s1
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US Patent
241 -35.1n/an/an/an/an/a7.84



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213110
PNG
((R,S)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21-/m0/s1
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US Patent
341 -34.3n/an/an/an/an/a7.84



The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent


Assay Description
Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....


US Patent US9492405 (2016)


BindingDB Entry DOI: 10.7270/Q2CJ8CBM
More data for this
Ligand-Target Pair
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