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Compile Data Set for Download or QSAR

Found 5 hits of ph data with Target = 'Bromodomain testis-specific protein'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain testis-specific protein


(Homo sapiens)
BDBM106150
PNG
(US9695172, 3)
Show SMILES COc1cc(ccc1Nc1ccc2N(C)C(=O)c3ccccc3N(C)c2n1)C(=O)N1CCC(CC1)N1CCN(C)CC1
Show InChI InChI=1S/C32H39N7O3/c1-35-17-19-38(20-18-35)23-13-15-39(16-14-23)31(40)22-9-10-25(28(21-22)42-4)33-29-12-11-27-30(34-29)36(2)26-8-6-5-7-24(26)32(41)37(27)3/h5-12,21,23H,13-20H2,1-4H3,(H,33,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.68E+3n/an/an/an/a7.525



Dana-Farber Cancer Institute, Inc.

US Patent


Assay Description
Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...


US Patent US9695172 (2017)


BindingDB Entry DOI: 10.7270/Q2JD4TX8
More data for this
Ligand-Target Pair
Bromodomain testis-specific protein


(Homo sapiens)
BDBM106153
PNG
(US9695172, 2-227)
Show SMILES COc1cc(ccc1Nc1ccc2N(C)C(=O)c3ccccc3N(C)c2n1)C(=O)NC1CCN(C)CC1
Show InChI InChI=1S/C28H32N6O3/c1-32-15-13-19(14-16-32)29-27(35)18-9-10-21(24(17-18)37-4)30-25-12-11-23-26(31-25)33(2)22-8-6-5-7-20(22)28(36)34(23)3/h5-12,17,19H,13-16H2,1-4H3,(H,29,35)(H,30,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 5.41E+3n/an/an/an/a7.525



Dana-Farber Cancer Institute, Inc.

US Patent


Assay Description
Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...


US Patent US9695172 (2017)


BindingDB Entry DOI: 10.7270/Q2JD4TX8
More data for this
Ligand-Target Pair
Bromodomain testis-specific protein


(Homo sapiens)
BDBM50355500
PNG
(CHEMBL1908394 | US9695172, GSK461364)
Show SMILES C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(CN3CCN(C)CC3)cc12)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28,29)30)37-23-14-24(38-25(23)26(31)36)35-16-32-21-8-7-18(13-22(21)35)15-34-11-9-33(2)10-12-34/h3-8,13-14,16-17H,9-12,15H2,1-2H3,(H2,31,36)/t17-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a>5.00E+4n/an/an/an/a7.525



Dana-Farber Cancer Institute, Inc.

US Patent


Assay Description
Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...


US Patent US9695172 (2017)


BindingDB Entry DOI: 10.7270/Q2JD4TX8
More data for this
Ligand-Target Pair
Bromodomain testis-specific protein


(Homo sapiens)
BDBM50365262
PNG
( (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10124009, C...)
Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1
Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 147n/an/an/an/a7.525



Dana-Farber Cancer Institute, Inc.

US Patent


Assay Description
Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...


US Patent US9695172 (2017)


BindingDB Entry DOI: 10.7270/Q2JD4TX8
More data for this
Ligand-Target Pair
Bromodomain testis-specific protein


(Homo sapiens)
BDBM106152
PNG
(US9695172, 2-221)
Show SMILES CN1c2ccccc2C(=O)N(C)c2ccc(Nc3ccc(cc3)S(N)(=O)=O)nc12
Show InChI InChI=1S/C20H19N5O3S/c1-24-16-6-4-3-5-15(16)20(26)25(2)17-11-12-18(23-19(17)24)22-13-7-9-14(10-8-13)29(21,27)28/h3-12H,1-2H3,(H,22,23)(H2,21,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 5.66E+3n/an/an/an/a7.525



Dana-Farber Cancer Institute, Inc.

US Patent


Assay Description
Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...


US Patent US9695172 (2017)


BindingDB Entry DOI: 10.7270/Q2JD4TX8
More data for this
Ligand-Target Pair