Compile Data Set for Download or QSAR

Found 147 hits of ph data with Target = 'Bromodomain-containing protein 4 (BRD4 (aa 1-477)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237391 (US9393232, 1.1 | US9393232, 1.1a | US9393232, 1.1b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccccc1 Show InChI InChI=1S/C19H16N2O3/c1-11-17(12(2)24-21-11)13-8-9-16-15(10-13)19(23,18(22)20-16)14-6-4-3-5-7-14/h3-10,23H,1-2H3,(H,20,22)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237391 (US9393232, 1.1 | US9393232, 1.1a | US9393232, 1.1b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccccc1 Show InChI InChI=1S/C19H16N2O3/c1-11-17(12(2)24-21-11)13-8-9-16-15(10-13)19(23,18(22)20-16)14-6-4-3-5-7-14/h3-10,23H,1-2H3,(H,20,22)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237391 (US9393232, 1.1 | US9393232, 1.1a | US9393232, 1.1b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccccc1 Show InChI InChI=1S/C19H16N2O3/c1-11-17(12(2)24-21-11)13-8-9-16-15(10-13)19(23,18(22)20-16)14-6-4-3-5-7-14/h3-10,23H,1-2H3,(H,20,22)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237394 (US9393232, 1.2) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H15ClN2O3/c1-10-17(11(2)25-22-10)12-3-8-16-15(9-12)19(24,18(23)21-16)13-4-6-14(20)7-5-13/h3-9,24H,1-2H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237395 (US9393232, 1.3) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1cccc(Cl)c1 Show InChI InChI=1S/C19H15ClN2O3/c1-10-17(11(2)25-22-10)12-6-7-16-15(8-12)19(24,18(23)21-16)13-4-3-5-14(20)9-13/h3-9,24H,1-2H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237396 (US9393232, 1.4) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccc(F)cc1 Show InChI InChI=1S/C19H15FN2O3/c1-10-17(11(2)25-22-10)12-3-8-16-15(9-12)19(24,18(23)21-16)13-4-6-14(20)7-5-13/h3-9,24H,1-2H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237397 (US9393232, 1.5) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccc(C)cc1 Show InChI InChI=1S/C20H18N2O3/c1-11-4-7-15(8-5-11)20(24)16-10-14(6-9-17(16)21-19(20)23)18-12(2)22-25-13(18)3/h4-10,24H,1-3H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237398 (US9393232, 1.6) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccc(F)c(C)c1 Show InChI InChI=1S/C20H17FN2O3/c1-10-8-14(5-6-16(10)21)20(25)15-9-13(4-7-17(15)22-19(20)24)18-11(2)23-26-12(18)3/h4-9,25H,1-3H3,(H,22,24)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237399 (US9393232, 1.7) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccccc1C Show InChI InChI=1S/C20H18N2O3/c1-11-6-4-5-7-15(11)20(24)16-10-14(8-9-17(16)21-19(20)23)18-12(2)22-25-13(18)3/h4-10,24H,1-3H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	570	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237400 (US9393232, 1.8) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1ccc(F)c(F)c1 Show InChI InChI=1S/C19H14F2N2O3/c1-9-17(10(2)26-23-9)11-3-6-16-13(7-11)19(25,18(24)22-16)12-4-5-14(20)15(21)8-12/h3-8,25H,1-2H3,(H,22,24)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237401 (US9393232, 1.9) Show SMILES COc1ccc(cc1)C1(O)C(=O)Nc2ccc(cc12)-c1c(C)noc1C Show InChI InChI=1S/C20H18N2O4/c1-11-18(12(2)26-22-11)13-4-9-17-16(10-13)20(24,19(23)21-17)14-5-7-15(25-3)8-6-14/h4-10,24H,1-3H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	410	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237402 (US9393232, 1.10) Show SMILES COc1ccc(cc1OC)C1(O)C(=O)Nc2ccc(cc12)-c1c(C)noc1C Show InChI InChI=1S/C21H20N2O5/c1-11-19(12(2)28-23-11)13-5-7-16-15(9-13)21(25,20(24)22-16)14-6-8-17(26-3)18(10-14)27-4/h5-10,25H,1-4H3,(H,22,24)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237403 (US9393232, 1.11) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)c1cccc2ccccc12 Show InChI InChI=1S/C23H18N2O3/c1-13-21(14(2)28-25-13)16-10-11-20-19(12-16)23(27,22(26)24-20)18-9-5-7-15-6-3-4-8-17(15)18/h3-12,27H,1-2H3,(H,24,26)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237404 (US9393232, 1.12) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C#Cc3ccccc3)c2c1 Show InChI InChI=1S/C21H16N2O3/c1-13-19(14(2)26-23-13)16-8-9-18-17(12-16)21(25,20(24)22-18)11-10-15-6-4-3-5-7-15/h3-9,12,25H,1-2H3,(H,22,24)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237405 (US9393232, 1.13) Show SMILES Cc1ccsc1C1(O)C(=O)Nc2ccc(cc12)-c1c(C)noc1C Show InChI InChI=1S/C18H16N2O3S/c1-9-6-7-24-16(9)18(22)13-8-12(4-5-14(13)19-17(18)21)15-10(2)20-23-11(15)3/h4-8,22H,1-3H3,(H,19,21)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	560	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237406 (US9393232, 1.14) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CCCCCC3)c2c1 Show InChI InChI=1S/C20H24N2O3/c1-12-18(13(2)25-22-12)14-9-10-17-16(11-14)20(24,19(23)21-17)15-7-5-3-4-6-8-15/h9-11,15,24H,3-8H2,1-2H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237407 (US9393232, 1.15) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CCCCC3)c2c1 Show InChI InChI=1S/C19H22N2O3/c1-11-17(12(2)24-21-11)13-8-9-16-15(10-13)19(23,18(22)20-16)14-6-4-3-5-7-14/h8-10,14,23H,3-7H2,1-2H3,(H,20,22)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237408 (US9393232, 1.16) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CCOCC3)c2c1 Show InChI InChI=1S/C18H20N2O4/c1-10-16(11(2)24-20-10)12-3-4-15-14(9-12)18(22,17(21)19-15)13-5-7-23-8-6-13/h3-4,9,13,22H,5-8H2,1-2H3,(H,19,21)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	630	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237409 (US9393232, 1.17) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CCCC3)c2c1 Show InChI InChI=1S/C18H20N2O3/c1-10-16(11(2)23-20-10)12-7-8-15-14(9-12)18(22,17(21)19-15)13-5-3-4-6-13/h7-9,13,22H,3-6H2,1-2H3,(H,19,21)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237410 (US9393232, 1.18) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CCC3)c2c1 Show InChI InChI=1S/C17H18N2O3/c1-9-15(10(2)22-19-9)11-6-7-14-13(8-11)17(21,16(20)18-14)12-4-3-5-12/h6-8,12,21H,3-5H2,1-2H3,(H,18,20)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237411 (US9393232, 1.19) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CC3)c2c1 Show InChI InChI=1S/C16H16N2O3/c1-8-14(9(2)21-18-8)10-3-6-13-12(7-10)16(20,11-4-5-11)15(19)17-13/h3,6-7,11,20H,4-5H2,1-2H3,(H,17,19)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	850	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237412 (US9393232, 1.20) Show SMILES CCC1(O)C(=O)Nc2ccc(cc12)-c1c(C)noc1C Show InChI InChI=1S/C15H16N2O3/c1-4-15(19)11-7-10(5-6-12(11)16-14(15)18)13-8(2)17-20-9(13)3/h5-7,19H,4H2,1-3H3,(H,16,18)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237413 (US9393232, 1.21) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C#C)c2c1 Show InChI InChI=1S/C15H12N2O3/c1-4-15(19)11-7-10(5-6-12(11)16-14(15)18)13-8(2)17-20-9(13)3/h1,5-7,19H,2-3H3,(H,16,18)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237414 (US9393232, 1.22) Show SMILES CC#CC1(O)C(=O)Nc2ccc(cc12)-c1c(C)noc1C Show InChI InChI=1S/C16H14N2O3/c1-4-7-16(20)12-8-11(5-6-13(12)17-15(16)19)14-9(2)18-21-10(14)3/h5-6,8,20H,1-3H3,(H,17,19)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237415 (US9393232, 1.23) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(CC=C)c2c1 Show InChI InChI=1S/C16H16N2O3/c1-4-7-16(20)12-8-11(5-6-13(12)17-15(16)19)14-9(2)18-21-10(14)3/h4-6,8,20H,1,7H2,2-3H3,(H,17,19)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237416 (US9393232, 1.24) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(CCC=C)c2c1 Show InChI InChI=1S/C17H18N2O3/c1-4-5-8-17(21)13-9-12(6-7-14(13)18-16(17)20)15-10(2)19-22-11(15)3/h4,6-7,9,21H,1,5,8H2,2-3H3,(H,18,20)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237417 (US9393232, 1.25) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(CCCC=C)c2c1 Show InChI InChI=1S/C18H20N2O3/c1-4-5-6-9-18(22)14-10-13(7-8-15(14)19-17(18)21)16-11(2)20-23-12(16)3/h4,7-8,10,22H,1,5-6,9H2,2-3H3,(H,19,21)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	540	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237418 (US9393232, 1.26) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c2c1)C(C)(C)C Show InChI InChI=1S/C17H20N2O3/c1-9-14(10(2)22-19-9)11-6-7-13-12(8-11)17(21,15(20)18-13)16(3,4)5/h6-8,21H,1-5H3,(H,18,20)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237419 (US9393232, 1.27) Show SMILES CC(C)C1(O)C(=O)Nc2ccc(cc12)-c1c(C)noc1C Show InChI InChI=1S/C16H18N2O3/c1-8(2)16(20)12-7-11(5-6-13(12)17-15(16)19)14-9(3)18-21-10(14)4/h5-8,20H,1-4H3,(H,17,19)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237420 (US9393232, 1.28) Show SMILES CC(=C)CC1(O)C(=O)Nc2ccc(cc12)-c1c(C)noc1C Show InChI InChI=1S/C17H18N2O3/c1-9(2)8-17(21)13-7-12(5-6-14(13)18-16(17)20)15-10(3)19-22-11(15)4/h5-7,21H,1,8H2,2-4H3,(H,18,20)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237421 (US9393232, 1.29) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(CCCc3ccccc3)c2c1 Show InChI InChI=1S/C22H22N2O3/c1-14-20(15(2)27-24-14)17-10-11-19-18(13-17)22(26,21(25)23-19)12-6-9-16-7-4-3-5-8-16/h3-5,7-8,10-11,13,26H,6,9,12H2,1-2H3,(H,23,25)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237422 (US9393232, 1.30a | US9393232, 1.30b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CCCCC3=O)c2c1 Show InChI InChI=1S/C19H20N2O4/c1-10-17(11(2)25-21-10)12-7-8-15-14(9-12)19(24,18(23)20-15)13-5-3-4-6-16(13)22/h7-9,13,24H,3-6H2,1-2H3,(H,20,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237422 (US9393232, 1.30a | US9393232, 1.30b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CCCCC3=O)c2c1 Show InChI InChI=1S/C19H20N2O4/c1-10-17(11(2)25-21-10)12-7-8-15-14(9-12)19(24,18(23)20-15)13-5-3-4-6-16(13)22/h7-9,13,24H,3-6H2,1-2H3,(H,20,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237423 (US9393232, 1.31) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(Cl)(c2c1)c1ccccc1 Show InChI InChI=1S/C19H15ClN2O2/c1-11-17(12(2)24-22-11)13-8-9-16-15(10-13)19(20,18(23)21-16)14-6-4-3-5-7-14/h3-10H,1-2H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237424 (US9393232, 1.32) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(OCCO)(c2c1)c1ccccc1 Show InChI InChI=1S/C21H20N2O4/c1-13-19(14(2)27-23-13)15-8-9-18-17(12-15)21(20(25)22-18,26-11-10-24)16-6-4-3-5-7-16/h3-9,12,24H,10-11H2,1-2H3,(H,22,25)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	79	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237425 (US9393232, 1.33) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(OCCO)(C3CCCCC3)c2c1 Show InChI InChI=1S/C21H26N2O4/c1-13-19(14(2)27-23-13)15-8-9-18-17(12-15)21(20(25)22-18,26-11-10-24)16-6-4-3-5-7-16/h8-9,12,16,24H,3-7,10-11H2,1-2H3,(H,22,25)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237426 (US9393232, 1.34) Show SMILES CC(=O)OC1(C(=O)Nc2ccc(cc12)-c1c(C)noc1C)c1ccccc1 Show InChI InChI=1S/C21H18N2O4/c1-12-19(13(2)27-23-12)15-9-10-18-17(11-15)21(20(25)22-18,26-14(3)24)16-7-5-4-6-8-16/h4-11H,1-3H3,(H,22,25)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237427 (US9393232, 2.1) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(NCCO)(c2c1)c1ccccc1 Show InChI InChI=1S/C21H21N3O3/c1-13-19(14(2)27-24-13)15-8-9-18-17(12-15)21(20(26)23-18,22-10-11-25)16-6-4-3-5-7-16/h3-9,12,22,25H,10-11H2,1-2H3,(H,23,26)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237428 (US9393232, 2.2 | US9393232, 2.2a | US9393232, 2.2b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N)(c2c1)c1ccccc1 Show InChI InChI=1S/C19H17N3O2/c1-11-17(12(2)24-22-11)13-8-9-16-15(10-13)19(20,18(23)21-16)14-6-4-3-5-7-14/h3-10H,20H2,1-2H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237428 (US9393232, 2.2 | US9393232, 2.2a | US9393232, 2.2b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N)(c2c1)c1ccccc1 Show InChI InChI=1S/C19H17N3O2/c1-11-17(12(2)24-22-11)13-8-9-16-15(10-13)19(20,18(23)21-16)14-6-4-3-5-7-14/h3-10H,20H2,1-2H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237428 (US9393232, 2.2 | US9393232, 2.2a | US9393232, 2.2b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N)(c2c1)c1ccccc1 Show InChI InChI=1S/C19H17N3O2/c1-11-17(12(2)24-22-11)13-8-9-16-15(10-13)19(20,18(23)21-16)14-6-4-3-5-7-14/h3-10H,20H2,1-2H3,(H,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237431 (US9393232, 2.3) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N3CCCCC3)(c2c1)c1ccccc1 Show InChI InChI=1S/C24H25N3O2/c1-16-22(17(2)29-26-16)18-11-12-21-20(15-18)24(23(28)25-21,19-9-5-3-6-10-19)27-13-7-4-8-14-27/h3,5-6,9-12,15H,4,7-8,13-14H2,1-2H3,(H,25,28)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237432 (US9393232, 2.4) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N3CCC(O)CC3)(c2c1)c1ccccc1 Show InChI InChI=1S/C24H25N3O3/c1-15-22(16(2)30-26-15)17-8-9-21-20(14-17)24(23(29)25-21,18-6-4-3-5-7-18)27-12-10-19(28)11-13-27/h3-9,14,19,28H,10-13H2,1-2H3,(H,25,29)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237433 (US9393232, 2.5) Show SMILES CN1CCN(CC1)C1(C(=O)Nc2ccc(cc12)-c1c(C)noc1C)c1ccccc1 Show InChI InChI=1S/C24H26N4O2/c1-16-22(17(2)30-26-16)18-9-10-21-20(15-18)24(23(29)25-21,19-7-5-4-6-8-19)28-13-11-27(3)12-14-28/h4-10,15H,11-14H2,1-3H3,(H,25,29)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237434 (US9393232, 2.6) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N3CCOCC3)(c2c1)c1ccccc1 Show InChI InChI=1S/C23H23N3O3/c1-15-21(16(2)29-25-15)17-8-9-20-19(14-17)23(22(27)24-20,18-6-4-3-5-7-18)26-10-12-28-13-11-26/h3-9,14H,10-13H2,1-2H3,(H,24,27)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237507 (US9393232, 2.7a | US9393232, 2.7b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N[C@@H](CO)c3ccccc3)(c2c1)c1ccccc1 Show InChI InChI=1S/C27H25N3O3/c1-17-25(18(2)33-30-17)20-13-14-23-22(15-20)27(26(32)28-23,21-11-7-4-8-12-21)29-24(16-31)19-9-5-3-6-10-19/h3-15,24,29,31H,16H2,1-2H3,(H,28,32)/t24-,27?/m0/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237507 (US9393232, 2.7a | US9393232, 2.7b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N[C@@H](CO)c3ccccc3)(c2c1)c1ccccc1 Show InChI InChI=1S/C27H25N3O3/c1-17-25(18(2)33-30-17)20-13-14-23-22(15-20)27(26(32)28-23,21-11-7-4-8-12-21)29-24(16-31)19-9-5-3-6-10-19/h3-15,24,29,31H,16H2,1-2H3,(H,28,32)/t24-,27?/m0/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	810	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237435 (US9393232, 2.8a | US9393232, 2.8b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N[C@H](CO)c3ccccc3)(c2c1)c1ccccc1 Show InChI InChI=1S/C27H25N3O3/c1-17-25(18(2)33-30-17)20-13-14-23-22(15-20)27(26(32)28-23,21-11-7-4-8-12-21)29-24(16-31)19-9-5-3-6-10-19/h3-15,24,29,31H,16H2,1-2H3,(H,28,32)/t24-,27?/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237435 (US9393232, 2.8a | US9393232, 2.8b) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N[C@H](CO)c3ccccc3)(c2c1)c1ccccc1 Show InChI InChI=1S/C27H25N3O3/c1-17-25(18(2)33-30-17)20-13-14-23-22(15-20)27(26(32)28-23,21-11-7-4-8-12-21)29-24(16-31)19-9-5-3-6-10-19/h3-15,24,29,31H,16H2,1-2H3,(H,28,32)/t24-,27?/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4 (aa 1-477) (Homo sapiens (Human))	BDBM237437 (US9393232, 2.9a | US9393232, 2.9b) Show SMILES C[C@@H](CO)NC1(C(=O)Nc2ccc(cc12)-c1c(C)noc1C)c1ccccc1 Show InChI InChI=1S/C22H23N3O3/c1-13(12-26)24-22(17-7-5-4-6-8-17)18-11-16(9-10-19(18)23-21(22)27)20-14(2)25-28-15(20)3/h4-11,13,24,26H,12H2,1-3H3,(H,23,27)/t13-,22?/m0/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	860	n/a	n/a	n/a	n/a	7.5	n/a
BeiGene, Ltd US Patent					Assay Description The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...				US Patent US9393232 (2016) BindingDB Entry DOI: 10.7270/Q25T3JDK
					More data for this Ligand-Target Pair

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