Compile Data Set for Download or QSAR

Found 43 hits of ph data with Target = 'C-Raf TR (aa 1-324)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202656 (US10245267, Example 1 | US10709712, Example 1 | US...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(ncn1)N1CCOCC1 Show InChI InChI=1S/C23H21F3N4O2/c1-15-5-6-18(29-22(31)16-3-2-4-17(11-16)23(24,25)26)12-19(15)20-13-21(28-14-27-20)30-7-9-32-10-8-30/h2-6,11-14H,7-10H2,1H3,(H,29,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.144	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202846 (US10245267, Example 199 | US10709712, Example 199 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1csc(n1)N1CCOCC1 Show InChI InChI=1S/C22H20F3N3O2S/c1-14-5-6-17(26-20(29)15-3-2-4-16(11-15)22(23,24)25)12-18(14)19-13-31-21(27-19)28-7-9-30-10-8-28/h2-6,11-13H,7-10H2,1H3,(H,26,29)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.29	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202661 (US10245267, Example 6 | US10709712, Example 6 | US...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(nc(n1)N1CCOCC1)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C27H28F3N5O4S/c1-18-5-6-21(31-25(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)23-17-24(34-9-13-40(37,38)14-10-34)33-26(32-23)35-7-11-39-12-8-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.408	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202662 (US10245267, Example 7 | US10709712, Example 7 | US...) Show SMILES Cc1ccc(cc1-c1cc(nc(n1)N1CCOCC1)N1CCS(=O)(=O)CC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H28F3N5O4S/c1-18-5-6-19(25(36)31-21-4-2-3-20(16-21)27(28,29)30)15-22(18)23-17-24(34-9-13-40(37,38)14-10-34)33-26(32-23)35-7-11-39-12-8-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.11	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202663 (US10709712, Example 8 | US9242969, 8 | US9242969, ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(nc(n1)N1CCS(=O)(=O)CC1)N1CCOCC1 Show InChI InChI=1S/C27H28F3N5O4S/c1-18-5-6-21(31-25(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)23-17-24(34-7-11-39-12-8-34)33-26(32-23)35-9-13-40(37,38)14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.514	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202663 (US10709712, Example 8 | US9242969, 8 | US9242969, ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(nc(n1)N1CCS(=O)(=O)CC1)N1CCOCC1 Show InChI InChI=1S/C27H28F3N5O4S/c1-18-5-6-21(31-25(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)23-17-24(34-7-11-39-12-8-34)33-26(32-23)35-9-13-40(37,38)14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.899	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202665 (US10245267, Example 10 | US10709712, Example 10 | ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C27H28F3N5O3/c1-18-5-6-21(31-25(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)23-17-24(34-7-11-37-12-8-34)33-26(32-23)35-9-13-38-14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.118	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202666 (US10245267, Example 11 | US10709712, Example 11 | ...) Show SMILES Cc1ccc(cc1-c1cc(nc(n1)N1CCOCC1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H28F3N5O3/c1-18-5-6-19(25(36)31-21-4-2-3-20(16-21)27(28,29)30)15-22(18)23-17-24(34-7-11-37-12-8-34)33-26(32-23)35-9-13-38-14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.580	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202668 (US10245267, Example 13 | US10709712, Example 13 | ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1nc(cc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C27H28F3N5O3/c1-18-5-6-21(31-26(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)25-32-23(34-7-11-37-12-8-34)17-24(33-25)35-9-13-38-14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.533	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202669 (US10245267, Example 14 | US10709712, Example 14 | ...) Show SMILES Cc1ccc(cc1-c1nc(cc(n1)N1CCOCC1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H28F3N5O3/c1-18-5-6-19(26(36)31-21-4-2-3-20(16-21)27(28,29)30)15-22(18)25-32-23(34-7-11-37-12-8-34)17-24(33-25)35-9-13-38-14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.803	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202696 (US10245267, Example 43 | US10709712, Example 42 | ...) Show SMILES CC(=C)c1cc(nc(n1)N1CCOCC1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C Show InChI InChI=1S/C26H25F3N4O2/c1-16(2)22-15-23(32-25(31-22)33-9-11-35-12-10-33)21-14-20(8-7-17(21)3)30-24(34)18-5-4-6-19(13-18)26(27,28)29/h4-8,13-15H,1,9-12H2,2-3H3,(H,30,34)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.137	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202697 (US10245267, Example 42 | US10709712, Example 43 | ...) Show SMILES CC(=C)c1cc(nc(n1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C)N1CCOCC1 Show InChI InChI=1S/C26H25F3N4O2/c1-16(2)22-15-23(33-9-11-35-12-10-33)32-24(31-22)21-14-20(8-7-17(21)3)30-25(34)18-5-4-6-19(13-18)26(27,28)29/h4-8,13-15H,1,9-12H2,2-3H3,(H,30,34)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.376	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202698 (US10245267, Example 44 | US10709712, Example 44 | ...) Show SMILES CC(C)c1cc(nc(n1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C)N1CCOCC1 Show InChI InChI=1S/C26H27F3N4O2/c1-16(2)22-15-23(33-9-11-35-12-10-33)32-24(31-22)21-14-20(8-7-17(21)3)30-25(34)18-5-4-6-19(13-18)26(27,28)29/h4-8,13-16H,9-12H2,1-3H3,(H,30,34)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.714	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202699 (US10245267, Example 45 | US10709712, Example 45 | ...) Show SMILES CC(C)c1cc(nc(n1)N1CCOCC1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C Show InChI InChI=1S/C26H27F3N4O2/c1-16(2)22-15-23(32-25(31-22)33-9-11-35-12-10-33)21-14-20(8-7-17(21)3)30-24(34)18-5-4-6-19(13-18)26(27,28)29/h4-8,13-16H,9-12H2,1-3H3,(H,30,34)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.02	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202717 (US10245267, Example 63 | US10709712, Example 63 | ...) Show SMILES Cc1ccc(cc1-c1ccnc(c1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H22F3N3O2/c1-16-5-6-18(23(31)29-20-4-2-3-19(15-20)24(25,26)27)13-21(16)17-7-8-28-22(14-17)30-9-11-32-12-10-30/h2-8,13-15H,9-12H2,1H3,(H,29,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.508	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202718 (US10245267, Example 111 | US10709712, Example 111 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(ccn1)N1CCOCC1 Show InChI InChI=1S/C24H22F3N3O2/c1-16-5-6-19(29-23(31)17-3-2-4-18(13-17)24(25,26)27)14-21(16)22-15-20(7-8-28-22)30-9-11-32-12-10-30/h2-8,13-15H,9-12H2,1H3,(H,29,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.847	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202764 (US10245267, Example 64 | US10709712, Example 64 | ...) Show SMILES Cc1ccc(cc1-c1cc(ccn1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H22F3N3O2/c1-16-5-6-17(23(31)29-19-4-2-3-18(14-19)24(25,26)27)13-21(16)22-15-20(7-8-28-22)30-9-11-32-12-10-30/h2-8,13-15H,9-12H2,1H3,(H,29,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.403	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202771 (US10245267, Example 118 | US10709712, Example 118 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cncc(n1)N1CCOCC1 Show InChI InChI=1S/C23H21F3N4O2/c1-15-5-6-18(28-22(31)16-3-2-4-17(11-16)23(24,25)26)12-19(15)20-13-27-14-21(29-20)30-7-9-32-10-8-30/h2-6,11-14H,7-10H2,1H3,(H,28,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.308	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202772 (US10245267, Example 119 | US10709712, Example 119 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cn(C)c(=O)c(n1)N1CCOCC1 Show InChI InChI=1S/C24H23F3N4O3/c1-15-6-7-18(28-22(32)16-4-3-5-17(12-16)24(25,26)27)13-19(15)20-14-30(2)23(33)21(29-20)31-8-10-34-11-9-31/h3-7,12-14H,8-11H2,1-2H3,(H,28,32)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202843 (US10245267, Example 196 | US10709712, Example 196 ...) Show SMILES COc1cc(nc(c1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C)N1CCOCC1 Show InChI InChI=1S/C25H24F3N3O3/c1-16-6-7-19(29-24(32)17-4-3-5-18(12-17)25(26,27)28)13-21(16)22-14-20(33-2)15-23(30-22)31-8-10-34-11-9-31/h3-7,12-15H,8-11H2,1-2H3,(H,29,32)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.621	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202845 (US10245267, Example 198 | US10709712, Example 198 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cnc(s1)N1CCOCC1 Show InChI InChI=1S/C22H20F3N3O2S/c1-14-5-6-17(27-20(29)15-3-2-4-16(11-15)22(23,24)25)12-18(14)19-13-26-21(31-19)28-7-9-30-10-8-28/h2-6,11-13H,7-10H2,1H3,(H,27,29)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.455	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202846 (US10245267, Example 199 | US10709712, Example 199 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1csc(n1)N1CCOCC1 Show InChI InChI=1S/C22H20F3N3O2S/c1-14-5-6-17(26-20(29)15-3-2-4-16(11-15)22(23,24)25)12-18(14)19-13-31-21(27-19)28-7-9-30-10-8-28/h2-6,11-13H,7-10H2,1H3,(H,26,29)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.29	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202656 (US10245267, Example 1 | US10709712, Example 1 | US...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(ncn1)N1CCOCC1 Show InChI InChI=1S/C23H21F3N4O2/c1-15-5-6-18(29-22(31)16-3-2-4-17(11-16)23(24,25)26)12-19(15)20-13-21(28-14-27-20)30-7-9-32-10-8-30/h2-6,11-14H,7-10H2,1H3,(H,29,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202657 (US10709712, Example 2 | US9242969, 2 | US9694016, ...) Show SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(C)(C)C#N)cc1-c1cc(ncn1)N1CCOCC1 Show InChI InChI=1S/C25H26N6O2/c1-17-4-5-19(30-24(32)18-6-7-27-22(12-18)25(2,3)15-26)13-20(17)21-14-23(29-16-28-21)31-8-10-33-11-9-31/h4-7,12-14,16H,8-11H2,1-3H3,(H,30,32)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2.95	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202661 (US10245267, Example 6 | US10709712, Example 6 | US...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(nc(n1)N1CCOCC1)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C27H28F3N5O4S/c1-18-5-6-21(31-25(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)23-17-24(34-9-13-40(37,38)14-10-34)33-26(32-23)35-7-11-39-12-8-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.410	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202662 (US10245267, Example 7 | US10709712, Example 7 | US...) Show SMILES Cc1ccc(cc1-c1cc(nc(n1)N1CCOCC1)N1CCS(=O)(=O)CC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H28F3N5O4S/c1-18-5-6-19(25(36)31-21-4-2-3-20(16-21)27(28,29)30)15-22(18)23-17-24(34-9-13-40(37,38)14-10-34)33-26(32-23)35-7-11-39-12-8-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.11	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202663 (US10709712, Example 8 | US9242969, 8 | US9242969, ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(nc(n1)N1CCS(=O)(=O)CC1)N1CCOCC1 Show InChI InChI=1S/C27H28F3N5O4S/c1-18-5-6-21(31-25(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)23-17-24(34-7-11-39-12-8-34)33-26(32-23)35-9-13-40(37,38)14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.510	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM77059 (US10245267, Example 9 | US10709712, Example 9 | US...) Show SMILES Cc1ccc(cc1-c1cc(nc(n1)N1CCS(=O)(=O)CC1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H28F3N5O4S/c1-18-5-6-19(25(36)31-21-4-2-3-20(16-21)27(28,29)30)15-22(18)23-17-24(34-7-11-39-12-8-34)33-26(32-23)35-9-13-40(37,38)14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202665 (US10245267, Example 10 | US10709712, Example 10 | ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C27H28F3N5O3/c1-18-5-6-21(31-25(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)23-17-24(34-7-11-37-12-8-34)33-26(32-23)35-9-13-38-14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202666 (US10245267, Example 11 | US10709712, Example 11 | ...) Show SMILES Cc1ccc(cc1-c1cc(nc(n1)N1CCOCC1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H28F3N5O3/c1-18-5-6-19(25(36)31-21-4-2-3-20(16-21)27(28,29)30)15-22(18)23-17-24(34-7-11-37-12-8-34)33-26(32-23)35-9-13-38-14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.580	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202668 (US10245267, Example 13 | US10709712, Example 13 | ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1nc(cc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C27H28F3N5O3/c1-18-5-6-21(31-26(36)19-3-2-4-20(15-19)27(28,29)30)16-22(18)25-32-23(34-7-11-37-12-8-34)17-24(33-25)35-9-13-38-14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202669 (US10245267, Example 14 | US10709712, Example 14 | ...) Show SMILES Cc1ccc(cc1-c1nc(cc(n1)N1CCOCC1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H28F3N5O3/c1-18-5-6-19(26(36)31-21-4-2-3-20(16-21)27(28,29)30)15-22(18)25-32-23(34-7-11-37-12-8-34)17-24(33-25)35-9-13-38-14-10-35/h2-6,15-17H,7-14H2,1H3,(H,31,36)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202696 (US10245267, Example 43 | US10709712, Example 42 | ...) Show SMILES CC(=C)c1cc(nc(n1)N1CCOCC1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C Show InChI InChI=1S/C26H25F3N4O2/c1-16(2)22-15-23(32-25(31-22)33-9-11-35-12-10-33)21-14-20(8-7-17(21)3)30-24(34)18-5-4-6-19(13-18)26(27,28)29/h4-8,13-15H,1,9-12H2,2-3H3,(H,30,34)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202698 (US10245267, Example 44 | US10709712, Example 44 | ...) Show SMILES CC(C)c1cc(nc(n1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C)N1CCOCC1 Show InChI InChI=1S/C26H27F3N4O2/c1-16(2)22-15-23(33-9-11-35-12-10-33)32-24(31-22)21-14-20(8-7-17(21)3)30-25(34)18-5-4-6-19(13-18)26(27,28)29/h4-8,13-16H,9-12H2,1-3H3,(H,30,34)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202699 (US10245267, Example 45 | US10709712, Example 45 | ...) Show SMILES CC(C)c1cc(nc(n1)N1CCOCC1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C Show InChI InChI=1S/C26H27F3N4O2/c1-16(2)22-15-23(32-25(31-22)33-9-11-35-12-10-33)21-14-20(8-7-17(21)3)30-24(34)18-5-4-6-19(13-18)26(27,28)29/h4-8,13-16H,9-12H2,1-3H3,(H,30,34)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.02	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202717 (US10245267, Example 63 | US10709712, Example 63 | ...) Show SMILES Cc1ccc(cc1-c1ccnc(c1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H22F3N3O2/c1-16-5-6-18(23(31)29-20-4-2-3-19(15-20)24(25,26)27)13-21(16)17-7-8-28-22(14-17)30-9-11-32-12-10-30/h2-8,13-15H,9-12H2,1H3,(H,29,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.510	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202764 (US10245267, Example 64 | US10709712, Example 64 | ...) Show SMILES Cc1ccc(cc1-c1cc(ccn1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H22F3N3O2/c1-16-5-6-17(23(31)29-19-4-2-3-18(14-19)24(25,26)27)13-21(16)22-15-20(7-8-28-22)30-9-11-32-12-10-30/h2-8,13-15H,9-12H2,1H3,(H,29,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.850	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202718 (US10245267, Example 111 | US10709712, Example 111 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(ccn1)N1CCOCC1 Show InChI InChI=1S/C24H22F3N3O2/c1-16-5-6-19(29-23(31)17-3-2-4-18(13-17)24(25,26)27)14-21(16)22-15-20(7-8-28-22)30-9-11-32-12-10-30/h2-8,13-15H,9-12H2,1H3,(H,29,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202771 (US10245267, Example 118 | US10709712, Example 118 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cncc(n1)N1CCOCC1 Show InChI InChI=1S/C23H21F3N4O2/c1-15-5-6-18(28-22(31)16-3-2-4-17(11-16)23(24,25)26)12-19(15)20-13-27-14-21(29-20)30-7-9-32-10-8-30/h2-6,11-14H,7-10H2,1H3,(H,28,31)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202772 (US10245267, Example 119 | US10709712, Example 119 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cn(C)c(=O)c(n1)N1CCOCC1 Show InChI InChI=1S/C24H23F3N4O3/c1-15-6-7-18(28-22(32)16-4-3-5-17(12-16)24(25,26)27)13-19(15)20-14-30(2)23(33)21(29-20)31-8-10-34-11-9-31/h3-7,12-14H,8-11H2,1-2H3,(H,28,32)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202843 (US10245267, Example 196 | US10709712, Example 196 ...) Show SMILES COc1cc(nc(c1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C)N1CCOCC1 Show InChI InChI=1S/C25H24F3N3O3/c1-16-6-7-19(29-24(32)17-4-3-5-18(12-17)25(26,27)28)13-21(16)22-14-20(33-2)15-23(30-22)31-8-10-34-11-9-31/h3-7,12-15H,8-11H2,1-2H3,(H,29,32)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.620	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202845 (US10245267, Example 198 | US10709712, Example 198 ...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cnc(s1)N1CCOCC1 Show InChI InChI=1S/C22H20F3N3O2S/c1-14-5-6-17(27-20(29)15-3-2-4-16(11-15)22(23,24)25)12-18(14)19-13-26-21(31-19)28-7-9-30-10-8-28/h2-6,11-13H,7-10H2,1H3,(H,27,29)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.460	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...				US Patent US9694016 (2017) BindingDB Entry DOI: 10.7270/Q2MC8X6W
					More data for this Ligand-Target Pair
C-Raf TR (aa 1-324) (Homo sapiens (Human))	BDBM202657 (US10709712, Example 2 | US9242969, 2 | US9694016, ...) Show SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(C)(C)C#N)cc1-c1cc(ncn1)N1CCOCC1 Show InChI InChI=1S/C25H26N6O2/c1-17-4-5-19(30-24(32)18-6-7-27-22(12-18)25(2,3)15-26)13-20(17)21-14-23(29-16-28-21)31-8-10-33-11-9-31/h4-7,12-14,16H,8-11H2,1-3H3,(H,30,32)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2.95	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...				US Patent US9242969 (2016) BindingDB Entry DOI: 10.7270/Q2VT1QXT
					More data for this Ligand-Target Pair