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Found 336 of ph data with Target = 'Cannabinoid receptor 2'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  398nM ΔG°:  -36.2kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29100(dibenzothiazepine, 12h)
Affinity DataKi:  1.00E+3nM ΔG°:  -33.9kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29097(dibenzothiazepine, 12c)
Affinity DataKi:  1.26E+3nM ΔG°:  -33.3kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29094((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)
Affinity DataKi:  2.00E+3nM ΔG°:  -32.2kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29099(dibenzothiazepine, 12g)
Affinity DataKi:  5.01E+3nM ΔG°:  -29.9kJ/molepH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29098(dibenzothiazepine, 12e)
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29101(dibenzothiazepine, 12j)
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29102(dibenzothiazepine, 12k)
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29095(dibenzothiazepine, 12a)
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM29096(dibenzothiazepine, 12b)
Affinity DatapH: 7.2 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM133313(US8846730, 79)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133287(US8846730, 40)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135877(US8859596, 164)
Affinity DataKi:  0.300nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133276(US8846730, 23)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133307(US8846730, 72)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM135855(US8859596, 141)
Affinity DataKi:  0.320nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM133287(US8846730, 40)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM135909(US8859596, 198)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM135905(US8859596, 193)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  0.450nM ΔG°:  -54.2kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133308(US8846730, 73)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133275(US8846730, 22)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM133316(US8846730, 83)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM133276(US8846730, 23)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM9807(US8846730, 50)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133315(US8846730, 81)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133313(US8846730, 79)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135905(US8859596, 193)
Affinity DataKi:  0.5nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135875(US8859596, 162)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM9651(US8846730, 4)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM135882(US8859596, 169)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM135857(US8859596, 144)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135882(US8859596, 169)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM9651(US8846730, 4)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM135911(US8859596, 200)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135904(US8859596, 192)
Affinity DataKi:  0.700nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM135904(US8859596, 192)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135860(US8859596, 147)
Affinity DataKi:  0.700nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM9652(US8846730, 5)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135908(US8859596, 197)
Affinity DataKi:  0.700nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM135903(US8859596, 191)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM9842(US8846730, 65 | US8846730, 76)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135878(US8859596, 165)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135857(US8859596, 144)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135900(US8859596, 188)
Affinity DataKi:  0.900nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135903(US8859596, 191)
Affinity DataKi:  0.900nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM133294(US8846730, 51)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM9812(US8846730, 69)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Acadia Pharmaceuticals

LigandPNGBDBM133307(US8846730, 72)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Abbvie

US Patent
LigandPNGBDBM135867(US8859596, 154)
Affinity DataKi:  1nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In DepthDetails US Patent
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