BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 970 hits of ph data with Target = 'Casein kinase II subunit beta (CK2 beta)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220044
PNG
(US9303033, N47, Table 58A, Compound 11)
Show SMILES CC(C)(C)NC(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C18H22N8O3/c1-18(2,3)25-17(29)23-12-7-13(20-10-4-5-10)26-14(22-12)9(8-19-26)6-11-15(27)24-16(28)21-11/h6-8,10,20H,4-5H2,1-3H3,(H2,21,24,27,28)(H2,22,23,25,29)/b11-6-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.82E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220047
PNG
(US9303033, Q47, Table 58A, Compound 14)
Show SMILES O=C(Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(c1)C#N
Show InChI InChI=1S/C21H16N8O3/c22-9-11-2-1-3-12(6-11)19(30)27-16-8-17(24-14-4-5-14)29-18(26-16)13(10-23-29)7-15-20(31)28-21(32)25-15/h1-3,6-8,10,14,24H,4-5H2,(H,26,27,30)(H2,25,28,31,32)/b15-7-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.75E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220054
PNG
(US9303033, D49, Table 59A, Compound 14 | US9303033...)
Show SMILES Clc1ccccc1COc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C19H16ClN7O3/c20-13-4-2-1-3-10(13)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-12-5-6-12/h1-4,7-8,12H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.97E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220063
PNG
(BDBM220095 | US9303033, G48, Table 58A, Compound 3...)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3cccc(c3)-n3cccn3)nc12
Show InChI InChI=1S/C22H19N9O2/c32-21-17(27-22(33)29-21)9-13-12-24-31-19(26-14-5-6-14)11-18(28-20(13)31)25-15-3-1-4-16(10-15)30-8-2-7-23-30/h1-4,7-12,14,26H,5-6H2,(H,25,28)(H2,27,29,32,33)/b17-9-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.73E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220066
PNG
(BDBM220085 | US9303033, J48, Table 58A, Compound 3...)
Show SMILES Cc1ccccc1-c1cc(F)ccc1CNc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C27H24FN7O2/c1-15-4-2-3-5-20(15)21-11-18(28)7-6-16(21)13-29-23-12-24(31-19-8-9-19)35-25(33-23)17(14-30-35)10-22-26(36)34-27(37)32-22/h2-7,10-12,14,19,31H,8-9,13H2,1H3,(H,29,33)(H2,32,34,36,37)/b22-10-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.73E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220072
PNG
(US9303033, P48, Table 58A, Compound 39)
Show SMILES COc1cccc(NC(=O)Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C21H20N8O4/c1-33-14-4-2-3-13(8-14)24-20(31)27-16-9-17(23-12-5-6-12)29-18(26-16)11(10-22-29)7-15-19(30)28-21(32)25-15/h2-4,7-10,12,23H,5-6H2,1H3,(H2,24,26,27,31)(H2,25,28,30,32)/b15-7-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.16E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220057
PNG
(US9303033, A48, Table 58A, Compound 24 | US9303033...)
Show SMILES Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1
Show InChI InChI=1S/C19H16ClN7O3/c20-12-3-1-10(2-4-12)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-13-5-6-13/h1-4,7-8,13H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.28E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219784
PNG
(US9303033, Q37, Table 41A, Compound 29)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3ccccc3C#N)nc12
Show InChI InChI=1S/C26H27N9O4S/c27-13-15-3-1-2-4-21(15)40(38,39)34-19-9-7-17(8-10-19)29-22-12-23(30-18-5-6-18)35-24(32-22)16(14-28-35)11-20-25(36)33-26(37)31-20/h1-4,11-12,14,17-19,30,34H,5-10H2,(H,29,32)(H2,31,33,36,37)/b20-11-/t17-,19-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219785
PNG
(US9303033, R37, Table 41A, Compound 30)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3cccc(c3)C#N)nc12
Show InChI InChI=1S/C25H26N10O4S/c26-12-14-2-1-3-19(10-14)40(38,39)34-18-8-6-16(7-9-18)28-23-31-21-15(11-20-22(36)32-25(37)30-20)13-27-35(21)24(33-23)29-17-4-5-17/h1-3,10-11,13,16-18,34H,4-9H2,(H2,28,29,31,33)(H2,30,32,36,37)/b20-11-/t16-,18-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219786
PNG
(US9303033, S37, Table 41A, Compound 31)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3cccc(c3)C#N)nc12
Show InChI InChI=1S/C26H27N9O4S/c27-13-15-2-1-3-20(10-15)40(38,39)34-19-8-6-17(7-9-19)29-22-12-23(30-18-4-5-18)35-24(32-22)16(14-28-35)11-21-25(36)33-26(37)31-21/h1-3,10-12,14,17-19,30,34H,4-9H2,(H,29,32)(H2,31,33,36,37)/b21-11-/t17-,19-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219787
PNG
(US9303033, T37, Table 41A, Compound 32)
Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C24H25F2N9O4S/c25-13-1-8-19(17(26)10-13)40(38,39)34-16-6-4-14(5-7-16)28-22-31-20-12(9-18-21(36)32-24(37)30-18)11-27-35(20)23(33-22)29-15-2-3-15/h1,8-11,14-16,34H,2-7H2,(H2,28,29,31,33)(H2,30,32,36,37)/b18-9-/t14-,16-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219788
PNG
(US9303033, U37, Table 41A, Compound 33)
Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C25H26F2N8O4S/c26-14-1-8-20(18(27)10-14)40(38,39)34-17-6-4-15(5-7-17)29-21-11-22(30-16-2-3-16)35-23(32-21)13(12-28-35)9-19-24(36)33-25(37)31-19/h1,8-12,15-17,30,34H,2-7H2,(H,29,32)(H2,31,33,36,37)/b19-9-/t15-,17-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219789
PNG
(US9303033, V37, Table 41A, Compound 34)
Show SMILES O=C(CC1CC1)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H29N9O3/c33-18(9-12-1-2-12)25-14-3-5-15(6-4-14)26-21-29-19-13(10-17-20(34)30-23(35)28-17)11-24-32(19)22(31-21)27-16-7-8-16/h10-12,14-16H,1-9H2,(H,25,33)(H2,26,27,29,31)(H2,28,30,34,35)/b17-10-/t14-,15-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219790
PNG
(US9303033, W37, Table 41A, Compound 35)
Show SMILES O=C(CC1CC1)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C24H30N8O3/c33-21(9-13-1-2-13)28-17-7-3-15(4-8-17)26-19-11-20(27-16-5-6-16)32-22(30-19)14(12-25-32)10-18-23(34)31-24(35)29-18/h10-13,15-17,27H,1-9H2,(H,26,30)(H,28,33)(H2,29,31,34,35)/b18-10-/t15-,17-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219791
PNG
(US9303033, X37, Table 41A, Compound 36)
Show SMILES CC1(CC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H29N9O3/c1-23(8-9-23)19(34)25-13-2-4-14(5-3-13)26-20-29-17-12(10-16-18(33)30-22(35)28-16)11-24-32(17)21(31-20)27-15-6-7-15/h10-11,13-15H,2-9H2,1H3,(H,25,34)(H2,26,27,29,31)(H2,28,30,33,35)/b16-10-/t13-,14-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219792
PNG
(US9303033, Y37, Table 41A, Compound 37)
Show SMILES CC1(CC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C24H30N8O3/c1-24(8-9-24)22(34)28-16-6-2-14(3-7-16)26-18-11-19(27-15-4-5-15)32-20(30-18)13(12-25-32)10-17-21(33)31-23(35)29-17/h10-12,14-16,27H,2-9H2,1H3,(H,26,30)(H,28,34)(H2,29,31,33,35)/b17-10-/t14-,16-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219793
PNG
(US9303033, Z37, Table 41A, Compound 38)
Show SMILES CC1CC1C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H29N9O3/c1-11-8-16(11)19(33)25-13-2-4-14(5-3-13)26-21-29-18-12(9-17-20(34)30-23(35)28-17)10-24-32(18)22(31-21)27-15-6-7-15/h9-11,13-16H,2-8H2,1H3,(H,25,33)(H2,26,27,29,31)(H2,28,30,34,35)/b17-9-/t11?,13-,14-,16?
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219794
PNG
(US9303033, A38, Table 41A, Compound 39)
Show SMILES CC1CC1C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C24H30N8O3/c1-12-8-17(12)22(33)28-16-6-2-14(3-7-16)26-19-10-20(27-15-4-5-15)32-21(30-19)13(11-25-32)9-18-23(34)31-24(35)29-18/h9-12,14-17,27H,2-8H2,1H3,(H,26,30)(H,28,33)(H2,29,31,34,35)/b18-9-/t12?,14-,16-,17?
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219795
PNG
(US9303033, B38, Table 41A, Compound 40)
Show SMILES O=C(N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CCC1
Show InChI InChI=1S/C23H29N9O3/c33-19(12-2-1-3-12)25-14-4-6-15(7-5-14)26-21-29-18-13(10-17-20(34)30-23(35)28-17)11-24-32(18)22(31-21)27-16-8-9-16/h10-12,14-16H,1-9H2,(H,25,33)(H2,26,27,29,31)(H2,28,30,34,35)/b17-10-/t14-,15-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219796
PNG
(US9303033, C38, Table 41A, Compound 41)
Show SMILES O=C(N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CCC1
Show InChI InChI=1S/C24H30N8O3/c33-22(13-2-1-3-13)28-17-8-4-15(5-9-17)26-19-11-20(27-16-6-7-16)32-21(30-19)14(12-25-32)10-18-23(34)31-24(35)29-18/h10-13,15-17,27H,1-9H2,(H,26,30)(H,28,33)(H2,29,31,34,35)/b18-10-/t15-,17-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219797
PNG
(US9303033, D38, Table 41A, Compound 42)
Show SMILES O=C(N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1(CC1)C#N
Show InChI InChI=1S/C23H26N10O3/c24-11-23(7-8-23)19(35)26-13-1-3-14(4-2-13)27-20-30-17-12(9-16-18(34)31-22(36)29-16)10-25-33(17)21(32-20)28-15-5-6-15/h9-10,13-15H,1-8H2,(H,26,35)(H2,27,28,30,32)(H2,29,31,34,36)/b16-9-/t13-,14-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219798
PNG
(US9303033, E38, Table 41A, Compound 43)
Show SMILES O=C(N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1(CC1)C#N
Show InChI InChI=1S/C24H27N9O3/c25-12-24(7-8-24)22(35)29-16-5-1-14(2-6-16)27-18-10-19(28-15-3-4-15)33-20(31-18)13(11-26-33)9-17-21(34)32-23(36)30-17/h9-11,14-16,28H,1-8H2,(H,27,31)(H,29,35)(H2,30,32,34,36)/b17-9-/t14-,16-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219799
PNG
(US9303033, F38, Table 41A, Compound 44)
Show SMILES FC1(F)CC1C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C22H25F2N9O3/c23-22(24)8-14(22)17(34)26-11-1-3-12(4-2-11)27-19-30-16-10(7-15-18(35)31-21(36)29-15)9-25-33(16)20(32-19)28-13-5-6-13/h7,9,11-14H,1-6,8H2,(H,26,34)(H2,27,28,30,32)(H2,29,31,35,36)/b15-7-/t11-,12-,14?
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219800
PNG
(US9303033, G38, Table 41A, Compound 45)
Show SMILES FC1(F)CC1C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H26F2N8O3/c24-23(25)9-15(23)20(34)29-14-5-1-12(2-6-14)27-17-8-18(28-13-3-4-13)33-19(31-17)11(10-26-33)7-16-21(35)32-22(36)30-16/h7-8,10,12-15,28H,1-6,9H2,(H,27,31)(H,29,34)(H2,30,32,35,36)/b16-7-/t12-,14-,15?
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219801
PNG
(US9303033, H38, Table 41A, Compound 46)
Show SMILES O=C(CN1CCCCC1)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C25H34N10O3/c36-20(14-34-10-2-1-3-11-34)27-16-4-6-17(7-5-16)28-23-31-21-15(12-19-22(37)32-25(38)30-19)13-26-35(21)24(33-23)29-18-8-9-18/h12-13,16-18H,1-11,14H2,(H,27,36)(H2,28,29,31,33)(H2,30,32,37,38)/b19-12-/t16-,17-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219802
PNG
(US9303033, I38, Table 41A, Compound 47)
Show SMILES O=C(CN1CCCCC1)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C26H35N9O3/c36-23(15-34-10-2-1-3-11-34)30-19-8-4-17(5-9-19)28-21-13-22(29-18-6-7-18)35-24(32-21)16(14-27-35)12-20-25(37)33-26(38)31-20/h12-14,17-19,29H,1-11,15H2,(H,28,32)(H,30,36)(H2,31,33,37,38)/b20-12-/t17-,19-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219803
PNG
(US9303033, J38, Table 41A, Compound 48)
Show SMILES O=C(CCN1CCCC1)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C25H34N10O3/c36-20(9-12-34-10-1-2-11-34)27-16-3-5-17(6-4-16)28-23-31-21-15(13-19-22(37)32-25(38)30-19)14-26-35(21)24(33-23)29-18-7-8-18/h13-14,16-18H,1-12H2,(H,27,36)(H2,28,29,31,33)(H2,30,32,37,38)/b19-13-/t16-,17-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219804
PNG
(US9303033, K38, Table 41A, Compound 49)
Show SMILES O=C(CCN1CCCC1)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C26H35N9O3/c36-23(9-12-34-10-1-2-11-34)30-19-7-3-17(4-8-19)28-21-14-22(29-18-5-6-18)35-24(32-21)16(15-27-35)13-20-25(37)33-26(38)31-20/h13-15,17-19,29H,1-12H2,(H,28,32)(H,30,36)(H2,31,33,37,38)/b20-13-/t17-,19-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219805
PNG
(US9303033, L38, Table 41A, Compound 50)
Show SMILES CC(N1CCCC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C25H34N10O3/c1-14(34-10-2-3-11-34)21(36)27-16-4-6-17(7-5-16)28-23-31-20-15(12-19-22(37)32-25(38)30-19)13-26-35(20)24(33-23)29-18-8-9-18/h12-14,16-18H,2-11H2,1H3,(H,27,36)(H2,28,29,31,33)(H2,30,32,37,38)/b19-12-/t14?,16-,17-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219806
PNG
(US9303033, M38, Table 41A, Compound 51)
Show SMILES CC(N1CCCC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C26H35N9O3/c1-15(34-10-2-3-11-34)24(36)30-19-8-4-17(5-9-19)28-21-13-22(29-18-6-7-18)35-23(32-21)16(14-27-35)12-20-25(37)33-26(38)31-20/h12-15,17-19,29H,2-11H2,1H3,(H,28,32)(H,30,36)(H2,31,33,37,38)/b20-12-/t15?,17-,19-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219807
PNG
(US9303033, N38, Table 41A, Compound 52)
Show SMILES O=C(CN1CCOCC1)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C24H32N10O4/c35-19(13-33-7-9-38-10-8-33)26-15-1-3-16(4-2-15)27-22-30-20-14(11-18-21(36)31-24(37)29-18)12-25-34(20)23(32-22)28-17-5-6-17/h11-12,15-17H,1-10,13H2,(H,26,35)(H2,27,28,30,32)(H2,29,31,36,37)/b18-11-/t15-,16-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219808
PNG
(US9303033, O38, Table 41A, Compound 53)
Show SMILES O=C(CN1CCOCC1)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C25H33N9O4/c35-22(14-33-7-9-38-10-8-33)29-18-5-1-16(2-6-18)27-20-12-21(28-17-3-4-17)34-23(31-20)15(13-26-34)11-19-24(36)32-25(37)30-19/h11-13,16-18,28H,1-10,14H2,(H,27,31)(H,29,35)(H2,30,32,36,37)/b19-11-/t16-,18-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219809
PNG
(US9303033, P38, Table 41A, Compound 54)
Show SMILES FC(F)(F)C1(CC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H26F3N9O3/c24-23(25,26)22(7-8-22)18(37)28-12-1-3-13(4-2-12)29-19-32-16-11(9-15-17(36)33-21(38)31-15)10-27-35(16)20(34-19)30-14-5-6-14/h9-10,12-14H,1-8H2,(H,28,37)(H2,29,30,32,34)(H2,31,33,36,38)/b15-9-/t12-,13-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219810
PNG
(US9303033, Q38, Table 41A, Compound 55)
Show SMILES FC(F)(F)C1(CC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C24H27F3N8O3/c25-24(26,27)23(7-8-23)21(37)31-15-5-1-13(2-6-15)29-17-10-18(30-14-3-4-14)35-19(33-17)12(11-28-35)9-16-20(36)34-22(38)32-16/h9-11,13-15,30H,1-8H2,(H,29,33)(H,31,37)(H2,32,34,36,38)/b16-9-/t13-,15-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219811
PNG
(US9303033, R38, Table 41A, Compound 56)
Show SMILES CN1CCN(CC(=O)N[C@H]2CC[C@@H](CC2)Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1
Show InChI InChI=1S/C25H35N11O3/c1-34-8-10-35(11-9-34)14-20(37)27-16-2-4-17(5-3-16)28-23-31-21-15(12-19-22(38)32-25(39)30-19)13-26-36(21)24(33-23)29-18-6-7-18/h12-13,16-18H,2-11,14H2,1H3,(H,27,37)(H2,28,29,31,33)(H2,30,32,38,39)/b19-12-/t16-,17-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219812
PNG
(US9303033, S38, Table 41A, Compound 57)
Show SMILES CN1CCN(CC(=O)N[C@H]2CC[C@@H](CC2)Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1
Show InChI InChI=1S/C26H36N10O3/c1-34-8-10-35(11-9-34)15-23(37)30-19-6-2-17(3-7-19)28-21-13-22(29-18-4-5-18)36-24(32-21)16(14-27-36)12-20-25(38)33-26(39)31-20/h12-14,17-19,29H,2-11,15H2,1H3,(H,28,32)(H,30,37)(H2,31,33,38,39)/b20-12-/t17-,19-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219813
PNG
(US9303033, T38, Table 41A, Compound 58)
Show SMILES CC(C)CN[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C22H31N9O2/c1-12(2)10-23-14-3-5-15(6-4-14)25-20-28-18-13(9-17-19(32)29-22(33)27-17)11-24-31(18)21(30-20)26-16-7-8-16/h9,11-12,14-16,23H,3-8,10H2,1-2H3,(H2,25,26,28,30)(H2,27,29,32,33)/b17-9-/t14-,15-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219814
PNG
(US9303033, U38, Table 42A, Compound 1)
Show SMILES Clc1cccc(Oc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C19H15ClN6O3/c20-11-2-1-3-13(7-11)29-16-8-15(22-12-4-5-12)26-17(24-16)10(9-21-26)6-14-18(27)25-19(28)23-14/h1-3,6-9,12,22H,4-5H2,(H2,23,25,27,28)/b14-6-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM219815
PNG
(US9303033, V38, Table 42A, Compound 2)
Show SMILES Clc1cc(ccc1Oc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N
Show InChI InChI=1S/C20H14ClN7O3/c21-13-5-10(8-22)1-4-15(13)31-17-7-16(24-12-2-3-12)28-18(26-17)11(9-23-28)6-14-19(29)27-20(30)25-14/h1,4-7,9,12,24H,2-3H2,(H2,25,27,29,30)/b14-6-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220025
PNG
(US9303033, U46, Table 57A, Compound 1)
Show SMILES CC(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C19H22N8O3/c1-11(28)25-4-6-26(7-5-25)15-9-16(21-13-2-3-13)27-17(23-15)12(10-20-27)8-14-18(29)24-19(30)22-14/h8-10,13,21H,2-7H2,1H3,(H2,22,24,29,30)/b14-8-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.28E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220026
PNG
(US9303033, V46, Table 57A, Compound 2)
Show SMILES O=C(C1CC1)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C21H24N8O3/c30-19-15(24-21(32)26-19)9-13-11-22-29-17(23-14-3-4-14)10-16(25-18(13)29)27-5-7-28(8-6-27)20(31)12-1-2-12/h9-12,14,23H,1-8H2,(H2,24,26,30,32)/b15-9-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.85E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220027
PNG
(US9303033, W46, Table 57A, Compound 3)
Show SMILES FC(F)(F)C1(CC1)C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C22H23F3N8O3/c23-22(24,25)21(3-4-21)19(35)32-7-5-31(6-8-32)15-10-16(27-13-1-2-13)33-17(29-15)12(11-26-33)9-14-18(34)30-20(36)28-14/h9-11,13,27H,1-8H2,(H2,28,30,34,36)/b14-9-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.04E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220028
PNG
(US9303033, X46, Table 57A, Compound 4)
Show SMILES O=C(C1CCC1)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C22H26N8O3/c31-20-16(25-22(33)27-20)10-14-12-23-30-18(24-15-4-5-15)11-17(26-19(14)30)28-6-8-29(9-7-28)21(32)13-2-1-3-13/h10-13,15,24H,1-9H2,(H2,25,27,31,33)/b16-10-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.12E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220029
PNG
(US9303033, Y46, Table 57A, Compound 5)
Show SMILES O=C(CN1CCOCC1)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H29N9O4/c33-20(14-29-7-9-36-10-8-29)31-5-3-30(4-6-31)18-12-19(25-16-1-2-16)32-21(27-18)15(13-24-32)11-17-22(34)28-23(35)26-17/h11-13,16,25H,1-10,14H2,(H2,26,28,34,35)/b17-11-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.28E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220030
PNG
(US9303033, Z46, Table 57A, Compound 6)
Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C22H28N8O4/c1-22(2,3)34-21(33)29-8-6-28(7-9-29)16-11-17(24-14-4-5-14)30-18(26-16)13(12-23-30)10-15-19(31)27-20(32)25-15/h10-12,14,24H,4-9H2,1-3H3,(H2,25,27,31,32)/b15-10-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.18E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220031
PNG
(US9303033, A47, Table 57A, Compound 7)
Show SMILES CC1(CC1)C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C22H26N8O3/c1-22(4-5-22)20(32)29-8-6-28(7-9-29)16-11-17(24-14-2-3-14)30-18(26-16)13(12-23-30)10-15-19(31)27-21(33)25-15/h10-12,14,24H,2-9H2,1H3,(H2,25,27,31,33)/b15-10-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.07E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220032
PNG
(US9303033, B47, Table 57A, Compound 8)
Show SMILES FC1(F)CC1C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C21H22F2N8O3/c22-21(23)9-13(21)19(33)30-5-3-29(4-6-30)15-8-16(25-12-1-2-12)31-17(27-15)11(10-24-31)7-14-18(32)28-20(34)26-14/h7-8,10,12-13,25H,1-6,9H2,(H2,26,28,32,34)/b14-7-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.10E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220033
PNG
(US9303033, C47, Table 57A, Compound 9)
Show SMILES O=C(CC1CC1)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C22H26N8O3/c31-19(9-13-1-2-13)29-7-5-28(6-8-29)17-11-18(24-15-3-4-15)30-20(26-17)14(12-23-30)10-16-21(32)27-22(33)25-16/h10-13,15,24H,1-9H2,(H2,25,27,32,33)/b16-10-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.67E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220039
PNG
(US9303033, I47, Table 58A, Compound 6)
Show SMILES O=C(Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CNCCO1
Show InChI InChI=1S/C18H20N8O4/c27-16-11(22-18(29)25-16)5-9-7-20-26-14(21-10-1-2-10)6-13(23-15(9)26)24-17(28)12-8-19-3-4-30-12/h5-7,10,12,19,21H,1-4,8H2,(H,23,24,28)(H2,22,25,27,29)/b11-5-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.55E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220041
PNG
(US9303033, K47, Table 58A, Compound 8)
Show SMILES CCNC(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C16H18N8O3/c1-2-17-15(26)22-11-6-12(19-9-3-4-9)24-13(21-11)8(7-18-24)5-10-14(25)23-16(27)20-10/h5-7,9,19H,2-4H2,1H3,(H2,17,21,22,26)(H2,20,23,25,27)/b10-5-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.49E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 970 total )  |  Next  |  Last  >>
Jump to: