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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cathepsin B (Capra hircus (Goat)) | BDBM192658 (N’-(2-nitrophenylmethylene)benzohydrazide (1i...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet  | Purchase PC cid PC sid UniChem Similars | Article PubMed | 113 | -41.2 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192660 (N’-(4-nitrophenylmethylene)benzohydrazide (1k...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 120 | -41.1 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192659 (N’-(3-nitrophenylmethylene)benzohydrazide (1j...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 140 | -40.7 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192656 (N’-(3-methoxyphenylmethylene)benzohydrazide (...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 180 | -40.0 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192654 (N’-(4-chlorophenylmethylene)benzohydrazide (1...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 190 | -39.9 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192652 (N’-(2-chlorophenylmethylene)benzohydrazide (1...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 210 | -39.6 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192653 (N’-(3-chlorophenylmethylene)benzohydrazide (1...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 260 | -39.1 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192650 (N’-(phenylmethylene)benzohydrazide (1a)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 290 | -38.8 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192657 (N’-(4-methoxyphenylmethylene)benzohydrazide (...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 440 | -37.7 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192668 (2-phenyl-5-(4-nitrophenyl)-1,3,4-oxadiazole (2k)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 664 | -36.7 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192667 (2-phenyl-5-(2-nitrophenyl)-1,3,4-oxadiazole (2i)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 790 | -36.2 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192655 (N’-(2-methoxyphenylmethylene)benzohydrazide (...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 830 | -36.1 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM63525 (2-(3-nitrophenyl)-5-phenyl-1,3,4-oxadiazole | 2-ph...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.00E+3 | -35.6 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM48184 (2-(3-chlorophenyl)-5-phenyl-1,3,4-oxadiazole | 2-p...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.28E+3 | -35.0 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192662 (2-phenyl-5-(2-chlorophenyl)-1,3,4-oxadiazole (2c)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.62E+3 | -34.4 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192663 (2-phenyl-5-(4-chlorophenyl)-1,3,4-oxadiazole (2e)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.92E+3 | -33.9 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192661 (2,5-diphenyl-1,3,4-oxadiazole (2a)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 2.69E+3 | -33.1 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192665 (2-phenyl-5-(3-methoxyphenyl)-1,3,4-oxadiazole (2g)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 4.44E+3 | -31.8 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192664 (2-phenyl-5-(2-methoxyphenyl)-1,3,4-oxadiazole (2f)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 6.85E+3 | -30.7 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192651 (N’-(4-methylphenylmethylene)benzohydrazide (1...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 8.72E+3 | -30.0 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM192666 (2-phenyl-5-(4-methoxyphenyl)-1,3,4-oxadiazole (2h)) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 9.22E+3 | -29.9 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Capra hircus (Goat)) | BDBM49356 (2-(4-methylphenyl)-5-phenyl-1,3,4-oxadiazole | 2-P...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 1.13E+4 | -29.4 | n/a | n/a | n/a | n/a | n/a | 5.0 | 37 |
Kurukshetra University | Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba... | Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Rattus norvegicus) | BDBM36329 (Z-LG-AOMK 9c) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Stanford University | Assay Description Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and H | Nat Chem Biol 1: 33-8 (2005) Article DOI: 10.1038/nchembio707 BindingDB Entry DOI: 10.7270/Q22V2DGV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Rattus norvegicus) | BDBM36328 (Z-FR-AMOK 9b) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Stanford University | Assay Description Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and H | Nat Chem Biol 1: 33-8 (2005) Article DOI: 10.1038/nchembio707 BindingDB Entry DOI: 10.7270/Q22V2DGV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Rattus norvegicus) | BDBM36331 (Ac-YFR-AMOK 10b) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Stanford University | Assay Description Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and H | Nat Chem Biol 1: 33-8 (2005) Article DOI: 10.1038/nchembio707 BindingDB Entry DOI: 10.7270/Q22V2DGV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Rattus norvegicus) | BDBM36327 (Z-FG-AOMK 9a) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Stanford University | Assay Description Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and H | Nat Chem Biol 1: 33-8 (2005) Article DOI: 10.1038/nchembio707 BindingDB Entry DOI: 10.7270/Q22V2DGV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Rattus norvegicus) | BDBM36325 (Cathepsin Inhibitor III) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Stanford University | Assay Description Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and H | Nat Chem Biol 1: 33-8 (2005) Article DOI: 10.1038/nchembio707 BindingDB Entry DOI: 10.7270/Q22V2DGV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Rattus norvegicus) | BDBM36330 (AC-YFG-AMOK 10a) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Stanford University | Assay Description Protease enzyme inhibition assay targeting diverse member of the cysteine protease families:cathepsin B, Z, and H | Nat Chem Biol 1: 33-8 (2005) Article DOI: 10.1038/nchembio707 BindingDB Entry DOI: 10.7270/Q22V2DGV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16511 ((2S)-1-[(2S)-2-{[(2S,3S)-3-{[(1S)-1-({[(2-methoxy-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16510 ((2S,3S)-3-[[(1S)-1-(isoamylcarbamoyl)-3-methyl-but...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16509 ((2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarb...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16508 ((2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16506 ((2S)-1-(2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.53E+4 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16505 (BzlNH-tES-Ile-Pro-OBzl | CA inhibitor 8 | CA077 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16504 (CA inhibitor 7 | CA073 | PrNH-tES-Ile-Pro-OBzl | b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | DrugBank PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16503 (CA inhibitor 6 | CA074Me | PrNH-tES-Ile-Pro-OMe | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16502 ((2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(benzylcarbamoyl)oxi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | DrugBank PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16501 ((2S)-2-[(2S,3R)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16500 ((2S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16497 ((2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | DrugBank PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Cathepsin B (Bos taurus (bovine)) | BDBM16499 ((2S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxir...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | DrugBank PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | 6.0 | 40 |
Osaka University of Pharmaceutical Sciences | Assay Description Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor... | J Mol Biol 362: 979-93 (2006) Article DOI: 10.1016/j.jmb.2006.07.070 BindingDB Entry DOI: 10.7270/Q2DF6PGN | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Cathepsin B (Mus musculus) | BDBM36333 (LI-0 | Legumain Inhibitor -0) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | 6.25 | 25 |
Stanford University | Assay Description IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices). | ACS Chem Biol 5: 233-43 (2010) Article DOI: 10.1021/cb900232a BindingDB Entry DOI: 10.7270/Q2Z31X0W | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Mus musculus) | BDBM36332 (LI-1 | Legumain Inhibitor -1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+5 | n/a | n/a | n/a | n/a | 6.25 | 25 |
Stanford University | Assay Description IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices). | ACS Chem Biol 5: 233-43 (2010) Article DOI: 10.1021/cb900232a BindingDB Entry DOI: 10.7270/Q2Z31X0W | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cathepsin B (Mus musculus) | BDBM36334 (CID644294 | JPM 565 | JPM-OEt | US9345789, JPM-Oet) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | 6.25 | 25 |
Stanford University | Assay Description IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices). | ACS Chem Biol 5: 233-43 (2010) Article DOI: 10.1021/cb900232a BindingDB Entry DOI: 10.7270/Q2Z31X0W | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
