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Compile Data Set for Download or QSAR

Found 27 hits of ph data with Target = 'Cathepsin G'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin G


(Homo sapiens)
BDBM113301
PNG
(US9695194, 17)
Show SMILES COc1ccc(c(OC)c1)-c1nc2cc(OC)c(OC)cc2c(=O)o1
Show InChI InChI=1S/C18H17NO6/c1-21-10-5-6-11(14(7-10)22-2)17-19-13-9-16(24-4)15(23-3)8-12(13)18(20)25-17/h5-9H,1-4H3
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100 -41.6n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113297
PNG
(US9695194, 14)
Show SMILES CS(=O)(=O)c1ccccc1-c1nc2cc3OCCOc3cc2c(=O)o1
Show InChI InChI=1S/C17H13NO6S/c1-25(20,21)15-5-3-2-4-10(15)16-18-12-9-14-13(22-6-7-23-14)8-11(12)17(19)24-16/h2-5,8-9H,6-7H2,1H3
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200 -39.8n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113300
PNG
(US9695194, 16)
Show SMILES Clc1ccccc1-c1nc2cc3OCCOc3cc2c(=O)o1
Show InChI InChI=1S/C16H10ClNO4/c17-11-4-2-1-3-9(11)15-18-12-8-14-13(20-5-6-21-14)7-10(12)16(19)22-15/h1-4,7-8H,5-6H2
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400 -38.0n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113299
PNG
(US9695194, 15)
Show SMILES COC1CC(OC)=CC=C1c1nc2cc3OCCOc3cc2c(=O)o1
Show InChI InChI=1S/C18H17NO6/c1-21-10-3-4-11(14(7-10)22-2)17-19-13-9-16-15(23-5-6-24-16)8-12(13)18(20)25-17/h3-4,8-9,14H,5-7H2,1-2H3
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500 -37.4n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113293
PNG
(US9695194, 10)
Show SMILES CS(=O)(=O)c1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1
Show InChI InChI=1S/C18H15NO6S/c1-26(21,22)16-6-3-2-5-11(16)17-19-13-10-15-14(23-7-4-8-24-15)9-12(13)18(20)25-17/h2-3,5-6,9-10H,4,7-8H2,1H3
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500 -37.4n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113283
PNG
(US9695194, 8)
Show SMILES COc1ccc(c(OC)c1)-c1nc2cc3OCCCOc3cc2c(=O)o1
Show InChI InChI=1S/C19H17NO6/c1-22-11-4-5-12(15(8-11)23-2)18-20-14-10-17-16(24-6-3-7-25-17)9-13(14)19(21)26-18/h4-5,8-10H,3,6-7H2,1-2H3
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600 -36.9n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113119
PNG
(US9695194, 6)
Show SMILES COc1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1
Show InChI InChI=1S/C18H15NO5/c1-21-14-6-3-2-5-11(14)17-19-13-10-16-15(22-7-4-8-23-16)9-12(13)18(20)24-17/h2-3,5-6,9-10H,4,7-8H2,1H3
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700 -36.5n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113296
PNG
(US9695194, 13)
Show SMILES COc1ccccc1-c1nc2cc3OCCOc3cc2c(=O)o1
Show InChI InChI=1S/C17H13NO5/c1-20-13-5-3-2-4-10(13)16-18-12-9-15-14(21-6-7-22-15)8-11(12)17(19)23-16/h2-5,8-9H,6-7H2,1H3
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700 -36.5n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113295
PNG
(US9695194, 12)
Show SMILES COc1cc2nc(oc(=O)c2cc1OC)-c1ccccc1SC
Show InChI InChI=1S/C17H15NO4S/c1-20-13-8-11-12(9-14(13)21-2)18-16(22-17(11)19)10-6-4-5-7-15(10)23-3/h4-9H,1-3H3
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700 -36.5n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113067
PNG
(US9695194, 3)
Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccc(OC)cc1OC
Show InChI InChI=1S/C19H19NO6/c1-5-25-17-9-13-14(10-16(17)24-4)20-18(26-19(13)21)12-7-6-11(22-2)8-15(12)23-3/h6-10H,5H2,1-4H3
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1.10E+3 -35.4n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113069
PNG
(US9695194, 5)
Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1OC
Show InChI InChI=1S/C18H17NO5/c1-4-23-16-9-12-13(10-15(16)22-3)19-17(24-18(12)20)11-7-5-6-8-14(11)21-2/h5-10H,4H2,1-3H3
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1.20E+3 -35.2n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113292
PNG
(US9695194, 9)
Show SMILES CSc1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1
Show InChI InChI=1S/C18H15NO4S/c1-24-16-6-3-2-5-11(16)17-19-13-10-15-14(21-7-4-8-22-15)9-12(13)18(20)23-17/h2-3,5-6,9-10H,4,7-8H2,1H3
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1.30E+3 -34.9n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113248
PNG
(US9695194, 7)
Show SMILES Clc1ccccc1-c1nc2cc3OCCCOc3cc2c(=O)o1
Show InChI InChI=1S/C17H12ClNO4/c18-12-5-2-1-4-10(12)16-19-13-9-15-14(21-6-3-7-22-15)8-11(13)17(20)23-16/h1-2,4-5,8-9H,3,6-7H2
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1.90E+3 -34.0n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50289001
PNG
(2-(2-Iodo-phenyl)-6,7-dimethoxy-benzo[d][1,3]oxazi...)
Show SMILES COc1cc2nc(oc(=O)c2cc1OC)-c1ccccc1I
Show InChI InChI=1S/C16H12INO4/c1-20-13-7-10-12(8-14(13)21-2)18-15(22-16(10)19)9-5-3-4-6-11(9)17/h3-8H,1-2H3
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US Patent
1.90E+3 -34.0n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113068
PNG
(US9695194, 4)
Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1S(C)(=O)=O
Show InChI InChI=1S/C18H17NO6S/c1-4-24-15-9-12-13(10-14(15)23-2)19-17(25-18(12)20)11-7-5-6-8-16(11)26(3,21)22/h5-10H,4H2,1-3H3
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2.80E+3 -33.0n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113294
PNG
(US9695194, 11)
Show SMILES CC(C)c1ccc(-c2nc3cc4OCCCOc4cc3c(=O)o2)c(c1)C(C)C
Show InChI InChI=1S/C23H25NO4/c1-13(2)15-6-7-16(17(10-15)14(3)4)22-24-19-12-21-20(26-8-5-9-27-21)11-18(19)23(25)28-22/h6-7,10-14H,5,8-9H2,1-4H3
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>1.00E+4>-29.7n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113060
PNG
(US9695194, 1)
Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1SC
Show InChI InChI=1S/C18H17NO4S/c1-4-22-15-9-12-13(10-14(15)21-2)19-17(23-18(12)20)11-7-5-6-8-16(11)24-3/h5-10H,4H2,1-3H3
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>1.00E+4>-29.7n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM113065
PNG
(US9695194, 2)
Show SMILES CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1Cl
Show InChI InChI=1S/C17H14ClNO4/c1-3-22-15-8-11-13(9-14(15)21-2)19-16(23-17(11)20)10-6-4-5-7-12(10)18/h4-9H,3H2,1-2H3
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>1.00E+4>-29.7n/an/an/an/an/a7.237



SIXERA PHARMA AB

US Patent


Assay Description
Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...


US Patent US9695194 (2017)


BindingDB Entry DOI: 10.7270/Q2CN723D
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50279766
PNG
(CHEMBL213783 | {2-{5-Benzyloxy-4-[4-(5-benzyloxy-4...)
Show SMILES COc1cc(CO)c(OCc2ccccc2)cc1Cc1cc(OC)c(Cc2cc(OC)c(Cc3cc(OC)c(Cc4cc(OC)c(Cc5cc(O)ccc5OCC(O)=O)cc4OCc4ccccc4)cc3OCC(O)=O)cc2OCc2ccccc2)cc1OCC(O)=O
Show InChI InChI=1S/C74H72O19/c1-83-62-29-55(67(88-40-46-15-9-6-10-16-46)33-50(62)23-49-28-60(76)21-22-61(49)91-43-72(77)78)24-52-35-69(92-44-73(79)80)57(31-64(52)85-3)26-51-34-68(89-41-47-17-11-7-12-18-47)56(30-63(51)84-2)25-53-36-70(93-45-74(81)82)58(32-65(53)86-4)27-54-37-71(59(39-75)38-66(54)87-5)90-42-48-19-13-8-14-20-48/h6-22,28-38,75-76H,23-27,39-45H2,1-5H3,(H,77,78)(H,79,80)(H,81,82)
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Article
PubMed
1.50E+3n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50279767
PNG
(CHEMBL268343 | {5-[4-(2-Carboxymethoxy-5-methoxy-b...)
Show SMILES COc1ccc(OCC(O)=O)c(Cc2cc(OCCCCCc3ccccc3)c(Cc3cc(OCC(O)=O)c(Cc4cc(OCCCCCc5ccccc5)c(Cc5cc(OCC(O)=O)c(Cc6cc(OCCCCCc7ccccc7)c(C)cc6OC)cc5OC)cc4OC)cc3OC)cc2OC)c1
Show InChI InChI=1S/C87H98O18/c1-59-40-76(95-3)64(47-75(59)100-37-23-11-20-32-60-26-14-8-15-27-60)42-71-50-79(98-6)67(54-83(71)104-57-86(90)91)44-70-49-78(97-5)66(53-82(70)102-39-25-13-22-34-62-30-18-10-19-31-62)45-72-51-80(99-7)68(55-84(72)105-58-87(92)93)43-69-48-77(96-4)65(41-63-46-73(94-2)35-36-74(63)103-56-85(88)89)52-81(69)101-38-24-12-21-33-61-28-16-9-17-29-61/h8-10,14-19,26-31,35-36,40,46-55H,11-13,20-25,32-34,37-39,41-45,56-58H2,1-7H3,(H,88,89)(H,90,91)(H,92,93)
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>1.50E+4n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50279768
PNG
((2-{2-Benzyloxy-4-[2-benzyloxy-4-(2-benzyloxy-5-ca...)
Show SMILES OCc1cc(OCc2ccccc2)c(Cc2cc(OCc3ccccc3)c(Cc3cc(OCc4ccccc4)c(Cc4cc(O)ccc4OCC(O)=O)cc3OCC(O)=O)cc2OCC(O)=O)cc1OCC(O)=O
Show InChI InChI=1S/C57H52O17/c58-28-45-27-52(70-31-38-14-8-3-9-15-38)44(26-53(45)74-35-57(66)67)20-43-23-49(69-30-37-12-6-2-7-13-37)41(25-51(43)73-34-56(64)65)19-42-22-48(68-29-36-10-4-1-5-11-36)40(24-50(42)72-33-55(62)63)18-39-21-46(59)16-17-47(39)71-32-54(60)61/h1-17,21-27,58-59H,18-20,28-35H2,(H,60,61)(H,62,63)(H,64,65)(H,66,67)
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>1.50E+4n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50060330
PNG
(CHEMBL265335 | {5-[4-(2-Carboxymethoxy-5-methoxy-b...)
Show SMILES COc1ccc(OCC(O)=O)c(Cc2cc(OCCCc3ccccc3)c(Cc3cc(OCC(O)=O)c(Cc4cc(OCCCc5ccccc5)c(Cc5cc(OCC(O)=O)c(Cc6cc(OCCCc7ccccc7)c(C)cc6OC)cc5OC)cc4OC)cc3OC)cc2OC)c1
Show InChI InChI=1S/C81H86O18/c1-53-34-70(89-3)58(41-69(53)94-31-17-26-54-20-11-8-12-21-54)36-65-44-73(92-6)61(48-77(65)98-51-80(84)85)38-64-43-72(91-5)60(47-76(64)96-33-19-28-56-24-15-10-16-25-56)39-66-45-74(93-7)62(49-78(66)99-52-81(86)87)37-63-42-71(90-4)59(46-75(63)95-32-18-27-55-22-13-9-14-23-55)35-57-40-67(88-2)29-30-68(57)97-50-79(82)83/h8-16,20-25,29-30,34,40-49H,17-19,26-28,31-33,35-39,50-52H2,1-7H3,(H,82,83)(H,84,85)(H,86,87)
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>1.50E+4n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50279771
PNG
(CHEMBL217744 | [4-Benzyloxy-5-{5-benzyloxy-4-[5-be...)
Show SMILES OCc1cc(OCc2ccccc2)c(Cc2cc(OCc3ccccc3)c(Cc3cc(OCc4ccccc4)c(Cc4cc(OCc5ccccc5)c(Cc5cc(O)ccc5OCC(O)=O)cc4OCC(O)=O)cc3OCC(O)=O)cc2OCC(O)=O)cc1OCC(O)=O
Show InChI InChI=1S/C73H66O21/c74-36-58-35-67(89-40-49-19-11-4-12-20-49)57(34-68(58)94-45-73(84)85)26-56-30-63(88-39-48-17-9-3-10-18-48)53(33-66(56)93-44-72(82)83)25-55-29-62(87-38-47-15-7-2-8-16-47)52(32-65(55)92-43-71(80)81)24-54-28-61(86-37-46-13-5-1-6-14-46)51(31-64(54)91-42-70(78)79)23-50-27-59(75)21-22-60(50)90-41-69(76)77/h1-22,27-35,74-75H,23-26,36-45H2,(H,76,77)(H,78,79)(H,80,81)(H,82,83)(H,84,85)
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>1.50E+4n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50060332
PNG
(2-{5-[4-{2-carboxymethoxy-4-[4-(2-carboxymethoxy-5...)
Show SMILES COCCOCOc1cc(Cc2cc(OC)c(Cc3cc(OC)c(Cc4cc(OC)c(Cc5cc(OC)c(Cc6cc(OC)ccc6OCC(O)=O)cc5OCOCCOC)cc4OCC(O)=O)cc3OCOCCOC)cc2OCC(O)=O)c(OC)cc1C
Show InChI InChI=1S/C66H80O24/c1-41-19-55(77-6)43(26-54(41)88-38-82-16-13-73-2)21-48-27-56(78-7)45(31-60(48)86-36-65(69)70)24-51-30-59(81-10)47(34-63(51)90-40-84-18-15-75-4)22-49-28-57(79-8)46(32-61(49)87-37-66(71)72)23-50-29-58(80-9)44(33-62(50)89-39-83-17-14-74-3)20-42-25-52(76-5)11-12-53(42)85-35-64(67)68/h11-12,19,25-34H,13-18,20-24,35-40H2,1-10H3,(H,67,68)(H,69,70)(H,71,72)
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>1.50E+4n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50060329
PNG
(CHEMBL385442 | {2-{4-[5-Carboxymethoxy-4-(5-hydrox...)
Show SMILES COc1ccc(OCC(O)=O)c(Cc2cc(O)c(Cc3cc(OCC(O)=O)c(Cc4cc(O)c(Cc5cc(OCC(O)=O)c(Cc6cc(O)c(C)cc6OC)cc5OC)cc4OC)cc3OC)cc2OC)c1
Show InChI InChI=1S/C54H56O18/c1-29-10-45(65-3)33(17-41(29)55)14-38-22-48(68-6)36(24-50(38)71-27-53(60)61)12-31-21-47(67-5)35(19-43(31)57)15-39-23-49(69-7)37(25-51(39)72-28-54(62)63)11-30-20-46(66-4)34(18-42(30)56)13-32-16-40(64-2)8-9-44(32)70-26-52(58)59/h8-10,16-25,55-57H,11-15,26-28H2,1-7H3,(H,58,59)(H,60,61)(H,62,63)
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>1.50E+4n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50279765
PNG
(CHEMBL215405 | {2-{4-[5-Carboxymethoxy-4-(5-cycloh...)
Show SMILES COc1ccc(OCC(O)=O)c(Cc2cc(OCC3CCCCC3)c(Cc3cc(OCC(O)=O)c(Cc4cc(OCC5CCCCC5)c(Cc5cc(OCC(O)=O)c(Cc6cc(OCC7CCCCC7)c(C)cc6OC)cc5OC)cc4OC)cc3OC)cc2OC)c1
Show InChI InChI=1S/C75H92O18/c1-47-25-64(83-3)52(32-63(47)88-41-48-17-11-8-12-18-48)27-59-35-67(86-6)55(39-71(59)92-45-74(78)79)29-58-34-66(85-5)54(38-70(58)90-43-50-21-15-10-16-22-50)30-60-36-68(87-7)56(40-72(60)93-46-75(80)81)28-57-33-65(84-4)53(37-69(57)89-42-49-19-13-9-14-20-49)26-51-31-61(82-2)23-24-62(51)91-44-73(76)77/h23-25,31-40,48-50H,8-22,26-30,41-46H2,1-7H3,(H,76,77)(H,78,79)(H,80,81)
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>1.50E+4n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens)
BDBM50279770
PNG
(2-{4-benzyloxy-5-[5-benzyloxy-4-(5-benzyloxy-4-{5-...)
Show SMILES OCc1cc(OCc2ccccc2)c(Cc2cc(OCc3ccccc3)c(Cc3cc(OCc4ccccc4)c(Cc4cc(OCc5ccccc5)c(Cc5cc(OCc6ccccc6)c(Cc6cc(O)ccc6OCC(O)=O)cc5OCC(O)=O)cc4OCC(O)=O)cc3OCC(O)=O)cc2OCC(O)=O)cc1OCC(O)=O
Show InChI InChI=1S/C89H80O25/c90-44-71-43-82(108-49-60-24-14-5-15-25-60)70(42-83(71)114-55-89(102)103)32-69-37-77(107-48-59-22-12-4-13-23-59)65(41-81(69)113-54-88(100)101)31-68-36-76(106-47-58-20-10-3-11-21-58)64(40-80(68)112-53-87(98)99)30-67-35-75(105-46-57-18-8-2-9-19-57)63(39-79(67)111-52-86(96)97)29-66-34-74(104-45-56-16-6-1-7-17-56)62(38-78(66)110-51-85(94)95)28-61-33-72(91)26-27-73(61)109-50-84(92)93/h1-27,33-43,90-91H,28-32,44-55H2,(H,92,93)(H,94,95)(H,96,97)(H,98,99)(H,100,101)(H,102,103)
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>1.50E+4n/an/an/an/an/an/a7.5n/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of cathepsin G at pH 7.5 in HEPES buffer containing 200 mM NaCl with substrate Suc-Ala-Ala-Pro-Phe-pNA.


J Med Chem 40: 3408-22 (1997)


Article DOI: 10.1021/jm970251r
BindingDB Entry DOI: 10.7270/Q26D5S4T
More data for this
Ligand-Target Pair