BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 12 hits of ph data with Target = 'Cholecystokinin receptor'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin receptor


(MOUSE)
BDBM50092155
PNG
((4S,5R)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carboxyl...)
Show SMILES Brc1ccc(NC(=O)N2NC(=O)[C@H]([C@@H]2c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C22H18BrN3O2/c23-17-11-13-18(14-12-17)24-22(28)26-20(16-9-5-2-6-10-16)19(21(27)25-26)15-7-3-1-4-8-15/h1-14,19-20H,(H,24,28)(H,25,27)/t19-,20-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 31n/an/an/an/a6.5n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 7.4


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50060321
PNG
(1H-Indole-2-carboxylic acid ((R)-1-methyl-2-oxo-5-...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C1=O)c1ccccc1
Show InChI InChI=1S/C25H20N4O2/c1-29-21-14-8-6-12-18(21)22(16-9-3-2-4-10-16)27-23(25(29)31)28-24(30)20-15-17-11-5-7-13-19(17)26-20/h2-15,23,26H,1H3,(H,28,30)/t23-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 3.70E+3n/an/an/an/a6.5n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50006878
PNG
((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)cc2)C1=O)c1ccccc1
Show InChI InChI=1S/C24H22N4O2/c1-16-12-14-18(15-13-16)25-24(30)27-22-23(29)28(2)20-11-7-6-10-19(20)21(26-22)17-8-4-3-5-9-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2n/an/an/an/a6.5n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50061220
PNG
(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1
Show InChI InChI=1S/C24H22N4O2/c1-16-9-8-12-18(15-16)25-24(30)27-22-23(29)28(2)20-14-7-6-13-19(20)21(26-22)17-10-4-3-5-11-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 150n/an/an/an/a6.5n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50281730
PNG
(4-Chloro-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydr...)
Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)c2ccc(Cl)cc2)C1=O)c1ccccc1
Show InChI InChI=1S/C23H18ClN3O2/c1-27-19-10-6-5-9-18(19)20(15-7-3-2-4-8-15)25-21(23(27)29)26-22(28)16-11-13-17(24)14-12-16/h2-14,21H,1H3,(H,26,28)/t21-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.90E+3n/an/an/an/a6.5n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50281732
PNG
(4-Chloro-N-((R)-1-methyl-2-oxo-5-phenyl-2,3-dihydr...)
Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)c2ccc(Cl)cc2)C1=O)c1ccccc1
Show InChI InChI=1S/C23H18ClN3O2/c1-27-19-10-6-5-9-18(19)20(15-7-3-2-4-8-15)25-21(23(27)29)26-22(28)16-11-13-17(24)14-12-16/h2-14,21H,1H3,(H,26,28)/t21-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.10E+4n/an/an/an/a6.5n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (human))
BDBM50005463
PNG
((R)-1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-...)
Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)c2cc3ccccc3[nH]2)C1=O)c1ccccc1
Show InChI InChI=1S/C25H20N4O2/c1-29-21-14-8-6-12-18(21)22(16-9-3-2-4-10-16)27-23(25(29)31)28-24(30)20-15-17-11-5-7-13-19(17)26-20/h2-15,23,26H,1H3,(H,28,30)/t23-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 270n/an/an/an/a6.5n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50281729
PNG
((4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Show SMILES FC(F)(F)c1cc(NC(=S)N2NC(=O)[C@@H]([C@H]2c2ccccc2)c2ccccc2)ccc1Cl
Show InChI InChI=1S/C23H17ClF3N3OS/c24-18-12-11-16(13-17(18)23(25,26)27)28-22(32)30-20(15-9-5-2-6-10-15)19(21(31)29-30)14-7-3-1-4-8-14/h1-13,19-20H,(H,28,32)(H,29,31)/t19-,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 1.90E+3n/an/an/an/a7.4n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50281729
PNG
((4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Show SMILES FC(F)(F)c1cc(NC(=S)N2NC(=O)[C@@H]([C@H]2c2ccccc2)c2ccccc2)ccc1Cl
Show InChI InChI=1S/C23H17ClF3N3OS/c24-18-12-11-16(13-17(18)23(25,26)27)28-22(32)30-20(15-9-5-2-6-10-15)19(21(31)29-30)14-7-3-1-4-8-14/h1-13,19-20H,(H,28,32)(H,29,31)/t19-,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 880n/an/an/an/a7.4n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 7.4


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50281731
PNG
((4S,5R)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Show SMILES FC(F)(F)c1cc(NC(=S)N2NC(=O)[C@H]([C@@H]2c2ccccc2)c2ccccc2)ccc1Cl
Show InChI InChI=1S/C23H17ClF3N3OS/c24-18-12-11-16(13-17(18)23(25,26)27)28-22(32)30-20(15-9-5-2-6-10-15)19(21(31)29-30)14-7-3-1-4-8-14/h1-13,19-20H,(H,28,32)(H,29,31)/t19-,20-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 550n/an/an/an/a7.4n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 7.4


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50092155
PNG
((4S,5R)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carboxyl...)
Show SMILES Brc1ccc(NC(=O)N2NC(=O)[C@H]([C@@H]2c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C22H18BrN3O2/c23-17-11-13-18(14-12-17)24-22(28)26-20(16-9-5-2-6-10-16)19(21(27)25-26)15-7-3-1-4-8-15/h1-14,19-20H,(H,24,28)(H,25,27)/t19-,20-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 19n/an/an/an/a7.4n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50092157
PNG
((4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carboxyl...)
Show SMILES Brc1ccc(NC(=O)N2NC(=O)[C@@H]([C@H]2c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C22H18BrN3O2/c23-17-11-13-18(14-12-17)24-22(28)26-20(16-9-5-2-6-10-16)19(21(27)25-26)15-7-3-1-4-8-15/h1-14,19-20H,(H,24,28)(H,25,27)/t19-,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 370n/an/an/an/a7.4n/a



TBA

Curated by ChEMBL


Assay Description
The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 6.5


Bioorg Med Chem Lett 3: 875-880 (1993)


Article DOI: 10.1016/S0960-894X(00)80684-8
BindingDB Entry DOI: 10.7270/Q21C1WTM
More data for this
Ligand-Target Pair