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Compile Data Set for Download or QSAR

Found 10 hits of ph data with Target = 'Complement C1s'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement C1s


(Homo sapiens (Human))
BDBM93094
PNG
(2-Guanidino-4-methylguinazoline)
Show SMILES Cc1nc(NC(N)=N)nc2ccccc12
Show InChI InChI=1S/C10H11N5/c1-6-7-4-2-3-5-8(7)14-10(13-6)15-9(11)12/h2-5H,1H3,(H4,11,12,13,14,15)/q+1
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7.65E+4 -23.5n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM93100
PNG
(N-z-L-Tyr)
Show SMILES Oc1ccc(CC(NC(=O)c2ccccc2)C([O-])=O)cc1
Show InChI InChI=1S/C16H15NO4/c18-13-8-6-11(7-9-13)10-14(16(20)21)17-15(19)12-4-2-1-3-5-12/h1-9,14,18H,10H2,(H,17,19)(H,20,21)/p-1
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3.70E+5 -19.6n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM93095
PNG
(Alpha-Phenylguanidine)
Show SMILES NC(=N)Nc1ccccc1
Show InChI InChI=1S/C7H9N3/c8-7(9)10-6-4-2-1-3-5-6/h1-5H,(H4,8,9,10)/q+1
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5.48E+5 -18.6n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM772
PNG
(Benzamidine | CHEMBL79897 | [amino(phenyl)methylid...)
Show SMILES NC(=[NH2+])c1ccccc1
Show InChI InChI=1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)/p+1
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6.03E+5 -18.4n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM93101
PNG
(N-Chloroacetyl-L-tyrosine)
Show SMILES Oc1ccc(CC(NC(=O)CCl)C([O-])=O)cc1
Show InChI InChI=1S/C11H12ClNO4/c12-6-10(15)13-9(11(16)17)5-7-1-3-8(14)4-2-7/h1-4,9,14H,5-6H2,(H,13,15)(H,16,17)/p-1
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1.12E+6 -16.9n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM93096
PNG
(2-Guanidinobenzimidazole)
Show SMILES NC(=N)NC1=Nc2ccccc2NC1
Show InChI InChI=1S/C9H11N5/c10-9(11)14-8-5-12-6-3-1-2-4-7(6)13-8/h1-4,12H,5H2,(H4,10,11,13,14)/q+1
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2.97E+6 -14.4n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM93097
PNG
(Guanidinacetic)
Show SMILES NC(=N)NCC([O-])=O
Show InChI InChI=1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)/q+1/p-1
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4.37E+6 -13.5n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM93098
PNG
(2,2'-Dimethyl-1-guanidinopropane)
Show SMILES CC(C)(C)CNC(N)=N
Show InChI InChI=1S/C6H15N3/c1-6(2,3)4-9-5(7)8/h4H2,1-3H3,(H4,7,8,9)/q+1
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1.34E+7 -10.7n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM86154
PNG
(Aminoguanidine | CAS_2146 | NSC_2146)
Show SMILES NN=C(N)N
Show InChI InChI=1S/CH6N4/c2-1(3)5-4/h4H2,(H4,2,3,5)
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1.81E+7 -9.96n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair
Complement C1s


(Homo sapiens (Human))
BDBM93099
PNG
(p-Nitrobenzamidine)
Show SMILES NC(=N)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C7H7N3O2/c8-7(9)5-1-3-6(4-2-5)10(11)12/h1-4H,(H3,8,9)/q+1
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9.25E+7 -5.91n/an/an/an/an/a8.0525.5



Michigan State University



Assay Description
All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.


Biochemistry 8: 4503-10 (1969)


Article DOI: 10.1021/bi00839a042
BindingDB Entry DOI: 10.7270/Q22R3Q87
More data for this
Ligand-Target Pair