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Compile Data Set for Download or QSAR

Found 429 hits of ph data with Target = 'Cyclin-Dependent Kinase 1 (CDK1)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7457
PNG
(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)
Show SMILES Oc1ccc2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Show InChI InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
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n/an/a 790n/an/an/an/a7.030



Lawrence Berkeley National Laboratory



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 48: 737-43 (2005)


Article DOI: 10.1021/jm049353p
BindingDB Entry DOI: 10.7270/Q2M61HG4
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7458
PNG
(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)cc2o1
Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
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n/an/a 4.00E+3n/an/an/an/a7.030



Lawrence Berkeley National Laboratory



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 48: 737-43 (2005)


Article DOI: 10.1021/jm049353p
BindingDB Entry DOI: 10.7270/Q2M61HG4
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7459
PNG
(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
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n/an/a 6.20E+3n/an/an/an/a7.030



Lawrence Berkeley National Laboratory



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 48: 737-43 (2005)


Article DOI: 10.1021/jm049353p
BindingDB Entry DOI: 10.7270/Q2M61HG4
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM5655
PNG
(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Show SMILES CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl
Show InChI InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1
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n/an/a 210n/an/an/an/a7.030



Lawrence Berkeley National Laboratory



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 48: 737-43 (2005)


Article DOI: 10.1021/jm049353p
BindingDB Entry DOI: 10.7270/Q2M61HG4
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7461
PNG
(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccccc1
Show InChI InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
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n/an/a 7.10E+3n/an/an/an/a7.030



Lawrence Berkeley National Laboratory



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 48: 737-43 (2005)


Article DOI: 10.1021/jm049353p
BindingDB Entry DOI: 10.7270/Q2M61HG4
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7462
PNG
(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Show SMILES Oc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O
Show InChI InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H
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n/an/a 4.10E+4n/an/an/an/a7.030



Lawrence Berkeley National Laboratory



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 48: 737-43 (2005)


Article DOI: 10.1021/jm049353p
BindingDB Entry DOI: 10.7270/Q2M61HG4
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7460
PNG
(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Show SMILES Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Show InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
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n/an/a 7.50E+4n/an/an/an/a7.030



Lawrence Berkeley National Laboratory



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 48: 737-43 (2005)


Article DOI: 10.1021/jm049353p
BindingDB Entry DOI: 10.7270/Q2M61HG4
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7262
PNG
(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Show SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Show InChI InChI=1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)
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n/an/a 35n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7263
PNG
(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)
Show SMILES O=C1Cc2c([nH]c3ccc(cc23)C#N)-c2ccccc2N1
Show InChI InChI=1S/C17H11N3O/c18-9-10-5-6-15-12(7-10)13-8-16(21)19-14-4-2-1-3-11(14)17(13)20-15/h1-7,20H,8H2,(H,19,21)
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n/an/a 24n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7264
PNG
(2,3-dimethoxy-9-nitropaullone | 4,5-dimethoxy-14-n...)
Show SMILES COc1cc2NC(=O)Cc3c([nH]c4ccc(cc34)[N+]([O-])=O)-c2cc1OC
Show InChI InChI=1S/C18H15N3O5/c1-25-15-6-12-14(8-16(15)26-2)19-17(22)7-11-10-5-9(21(23)24)3-4-13(10)20-18(11)12/h3-6,8,20H,7H2,1-2H3,(H,19,22)
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n/an/a 24n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7265
PNG
(4,5-dimethoxy-9-oxo-8,18-diazatetracyclo[9.7.0.0^{...)
Show SMILES COc1cc2NC(=O)Cc3c([nH]c4ccc(cc34)C#N)-c2cc1OC
Show InChI InChI=1S/C19H15N3O3/c1-24-16-6-13-15(8-17(16)25-2)21-18(23)7-12-11-5-10(9-20)3-4-14(11)22-19(12)13/h3-6,8,22H,7H2,1-2H3,(H,21,23)
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n/an/a 44n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7266
PNG
(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Show SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Show InChI InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)
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n/an/a 400n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7267
PNG
(14-chloro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12...)
Show SMILES Clc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Show InChI InChI=1S/C16H11ClN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)
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n/an/a 600n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7268
PNG
(14-(trifluoromethyl)-8,18-diazatetracyclo[9.7.0.0^...)
Show SMILES FC(F)(F)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Show InChI InChI=1S/C17H11F3N2O/c18-17(19,20)9-5-6-14-11(7-9)12-8-15(23)21-13-4-2-1-3-10(13)16(12)22-14/h1-7,22H,8H2,(H,21,23)
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n/an/a 400n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7269
PNG
(3-(6-oxo-9-trifluoromethyl-5,6,7,12-tetrahydro-ind...)
Show SMILES FC(F)(F)c1ccc2[nH]c-3c(CC(=O)Nc4ccc(CCC#N)cc-34)c2c1
Show InChI InChI=1S/C20H14F3N3O/c21-20(22,23)12-4-6-16-13(9-12)14-10-18(27)25-17-5-3-11(2-1-7-24)8-15(17)19(14)26-16/h3-6,8-9,26H,1-2,10H2,(H,25,27)
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n/an/a 47n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7270
PNG
(2,3-dimethoxy-9-trifluoromethylpaullone | 4,5-dime...)
Show SMILES COc1cc2NC(=O)Cc3c([nH]c4ccc(cc34)C(F)(F)F)-c2cc1OC
Show InChI InChI=1S/C19H15F3N2O3/c1-26-15-6-12-14(8-16(15)27-2)23-17(25)7-11-10-5-9(19(20,21)22)3-4-13(10)24-18(11)12/h3-6,8,24H,7H2,1-2H3,(H,23,25)
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n/an/a 280n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7271
PNG
(9-bromo-12-methyloxycarbonylmethylpaullone | CHEMB...)
Show SMILES COC(=O)Cn1c-2c(CC(=O)Nc3ccccc-23)c2cc(Br)ccc12
Show InChI InChI=1S/C19H15BrN2O3/c1-25-18(24)10-22-16-7-6-11(20)8-13(16)14-9-17(23)21-15-5-3-2-4-12(15)19(14)22/h2-8H,9-10H2,1H3,(H,21,23)
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n/an/a 1.40E+3n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7272
PNG
(14-fluoro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12...)
Show SMILES Fc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Show InChI InChI=1S/C16H11FN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)
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n/an/a 1.60E+3n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7273
PNG
(14-bromo-4,5-dimethoxy-8,18-diazatetracyclo[9.7.0....)
Show SMILES COc1cc2NC(=O)Cc3c([nH]c4ccc(Br)cc34)-c2cc1OC
Show InChI InChI=1S/C18H15BrN2O3/c1-23-15-6-12-14(8-16(15)24-2)20-17(22)7-11-10-5-9(19)3-4-13(10)21-18(11)12/h3-6,8,21H,7H2,1-2H3,(H,20,22)
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n/an/a 200n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7274
PNG
(14-bromo-4,5-dihydroxy-8,18-diazatetracyclo[9.7.0....)
Show SMILES Oc1cc2NC(=O)Cc3c([nH]c4ccc(Br)cc34)-c2cc1O
Show InChI InChI=1S/C16H11BrN2O3/c17-7-1-2-11-8(3-7)9-5-15(22)18-12-6-14(21)13(20)4-10(12)16(9)19-11/h1-4,6,19-21H,5H2,(H,18,22)
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n/an/a 3.00E+3n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7275
PNG
(14-methyl-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12...)
Show SMILES Cc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Show InChI InChI=1S/C17H14N2O/c1-10-6-7-15-12(8-10)13-9-16(20)18-14-5-3-2-4-11(14)17(13)19-15/h2-8,19H,9H2,1H3,(H,18,20)
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n/an/a 2.00E+3n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7276
PNG
(10-bromopaullone | 15-bromo-8,18-diazatetracyclo[9...)
Show SMILES Brc1ccc2c3CC(=O)Nc4ccccc4-c3[nH]c2c1
Show InChI InChI=1S/C16H11BrN2O/c17-9-5-6-10-12-8-15(20)18-13-4-2-1-3-11(13)16(12)19-14(10)7-9/h1-7,19H,8H2,(H,18,20)
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n/an/a 1.30E+3n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7277
PNG
(2-Bromopaullone | 4-bromo-8,18-diazatetracyclo[9.7...)
Show SMILES Brc1ccc2NC(=O)Cc3c([nH]c4ccccc34)-c2c1
Show InChI InChI=1S/C16H11BrN2O/c17-9-5-6-14-12(7-9)16-11(8-15(20)18-14)10-3-1-2-4-13(10)19-16/h1-7,19H,8H2,(H,18,20)
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n/an/a 3.30E+3n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7278
PNG
(11-chloropaullone | 16-chloro-8,18-diazatetracyclo...)
Show SMILES Clc1cccc2c3CC(=O)Nc4ccccc4-c3[nH]c12
Show InChI InChI=1S/C16H11ClN2O/c17-12-6-3-5-9-11-8-14(20)18-13-7-2-1-4-10(13)15(11)19-16(9)12/h1-7,19H,8H2,(H,18,20)
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n/an/a 1.40E+3n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7279
PNG
(2-(3-hydroxy-1-propinyl)-9-trifluoromethylpaullone...)
Show SMILES OCC#Cc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)C(F)(F)F)-c2c1
Show InChI InChI=1S/C20H13F3N2O2/c21-20(22,23)12-4-6-16-13(9-12)14-10-18(27)24-17-5-3-11(2-1-7-26)8-15(17)19(14)25-16/h3-6,8-9,25-26H,7,10H2,(H,24,27)
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n/an/a 300n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7280
PNG
(2-Bromo-9-Nitropaullone | 4-bromo-14-nitro-8,18-di...)
Show SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccc(Br)cc-34)c2c1
Show InChI InChI=1S/C16H10BrN3O3/c17-8-1-3-14-12(5-8)16-11(7-15(21)18-14)10-6-9(20(22)23)2-4-13(10)19-16/h1-6,19H,7H2,(H,18,21)
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n/an/a 53n/an/an/an/a7.230



CNRS



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...


Eur J Biochem 267: 5983-94 (2000)


Article DOI: 10.1210/endo.137.7.8770901
BindingDB Entry DOI: 10.7270/Q2CR5RJS
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7451
PNG
(1-{12-hydroxy-3-phenyl-8-oxa-6-azatricyclo[7.4.0.0...)
Show SMILES CC(=O)c1cnc2oc3ccc(O)cc3c2c1-c1ccccc1
Show InChI InChI=1S/C19H13NO3/c1-11(21)15-10-20-19-18(17(15)12-5-3-2-4-6-12)14-9-13(22)7-8-16(14)23-19/h2-10,22H,1H3
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n/an/a 4.20E+3n/an/an/an/a7.230



Martin-Luther-University Halle-Wittenberg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


Bioorg Med Chem Lett 15: 823-5 (2005)


Article DOI: 10.1016/j.bmcl.2004.10.091
BindingDB Entry DOI: 10.7270/Q2QZ2853
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7452
PNG
(1-aza-9-oxafluorene deriv. 7a | 4-methyl-3-phenyl-...)
Show SMILES Cc1cnc2oc3ccc(O)cc3c2c1-c1ccccc1
Show InChI InChI=1S/C18H13NO2/c1-11-10-19-18-17(16(11)12-5-3-2-4-6-12)14-9-13(20)7-8-15(14)21-18/h2-10,20H,1H3
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n/an/a>1.00E+5n/an/an/an/a7.230



Martin-Luther-University Halle-Wittenberg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


Bioorg Med Chem Lett 15: 823-5 (2005)


Article DOI: 10.1016/j.bmcl.2004.10.091
BindingDB Entry DOI: 10.7270/Q2QZ2853
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7453
PNG
(1-aza-9-oxafluorene deriv. 7b | 4-methoxy-3-phenyl...)
Show SMILES COc1cnc2oc3ccc(O)cc3c2c1-c1ccccc1
Show InChI InChI=1S/C18H13NO3/c1-21-15-10-19-18-17(16(15)11-5-3-2-4-6-11)13-9-12(20)7-8-14(13)22-18/h2-10,20H,1H3
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n/an/a 6.43E+4n/an/an/an/a7.230



Martin-Luther-University Halle-Wittenberg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


Bioorg Med Chem Lett 15: 823-5 (2005)


Article DOI: 10.1016/j.bmcl.2004.10.091
BindingDB Entry DOI: 10.7270/Q2QZ2853
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7454
PNG
(1-aza-9-oxafluorene deriv. 7c | 4-ethoxy-3-phenyl-...)
Show SMILES CCOc1cnc2oc3ccc(O)cc3c2c1-c1ccccc1
Show InChI InChI=1S/C19H15NO3/c1-2-22-16-11-20-19-18(17(16)12-6-4-3-5-7-12)14-10-13(21)8-9-15(14)23-19/h3-11,21H,2H2,1H3
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n/an/a>1.00E+5n/an/an/an/a7.230



Martin-Luther-University Halle-Wittenberg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


Bioorg Med Chem Lett 15: 823-5 (2005)


Article DOI: 10.1016/j.bmcl.2004.10.091
BindingDB Entry DOI: 10.7270/Q2QZ2853
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7455
PNG
(1-aza-9-oxafluorene deriv. 7d | 4-chloro-3-phenyl-...)
Show SMILES Oc1ccc2oc3ncc(Cl)c(-c4ccccc4)c3c2c1
Show InChI InChI=1S/C17H10ClNO2/c18-13-9-19-17-16(15(13)10-4-2-1-3-5-10)12-8-11(20)6-7-14(12)21-17/h1-9,20H
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n/an/a>1.00E+5n/an/an/an/a7.230



Martin-Luther-University Halle-Wittenberg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


Bioorg Med Chem Lett 15: 823-5 (2005)


Article DOI: 10.1016/j.bmcl.2004.10.091
BindingDB Entry DOI: 10.7270/Q2QZ2853
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7456
PNG
(1-aza-9-oxafluorene deriv. 7e | 4-bromo-3-phenyl-8...)
Show SMILES Oc1ccc2oc3ncc(Br)c(-c4ccccc4)c3c2c1
Show InChI InChI=1S/C17H10BrNO2/c18-13-9-19-17-16(15(13)10-4-2-1-3-5-10)12-8-11(20)6-7-14(12)21-17/h1-9,20H
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n/an/a 7.07E+4n/an/an/an/a7.230



Martin-Luther-University Halle-Wittenberg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


Bioorg Med Chem Lett 15: 823-5 (2005)


Article DOI: 10.1016/j.bmcl.2004.10.091
BindingDB Entry DOI: 10.7270/Q2QZ2853
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7318
PNG
(14-bromo-4-iodo-8,18-diazatetracyclo[9.7.0.0^{2,7}...)
Show SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4ccc(I)cc-34)c2c1
Show InChI InChI=1S/C16H10BrIN2O/c17-8-1-3-13-10(5-8)11-7-15(21)19-14-4-2-9(18)6-12(14)16(11)20-13/h1-6,20H,7H2,(H,19,21)
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n/an/a 320n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7319
PNG
(6-Oxo-5,6,7,12-tetrahydro-indolo[3,2-d][1]benzazep...)
Show SMILES O=C1Cc2c([nH]c3ccccc23)-c2cc(ccc2N1)C#N
Show InChI InChI=1S/C17H11N3O/c18-9-10-5-6-15-13(7-10)17-12(8-16(21)19-15)11-3-1-2-4-14(11)20-17/h1-7,20H,8H2,(H,19,21)
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n/an/a 3.30E+3n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7320
PNG
(3-Methoxy-9-trifluormethyl-7,12-dihydro-indolo[3,2...)
Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)C(F)(F)F
Show InChI InChI=1S/C18H13F3N2O2/c1-25-10-3-4-11-15(7-10)22-16(24)8-13-12-6-9(18(19,20)21)2-5-14(12)23-17(11)13/h2-7,23H,8H2,1H3,(H,22,24)
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n/an/a 700n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7321
PNG
(14-amino-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Show SMILES Nc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Show InChI InChI=1S/C16H13N3O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8,17H2,(H,18,20)
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n/an/a 2.00E+4n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7322
PNG
(14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...)
Show SMILES Oc1ccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc2c1
Show InChI InChI=1S/C16H11BrN2O2/c17-8-1-4-13-11(5-8)12-7-15(21)18-14-6-9(20)2-3-10(14)16(12)19-13/h1-6,19-20H,7H2,(H,18,21)
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n/an/a 600n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7323
PNG
(9-Acetamido-7,12-dihydro-indolo[3,2-d][1]benzazepi...)
Show SMILES CC(=O)Nc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Show InChI InChI=1S/C18H15N3O2/c1-10(22)19-11-6-7-16-13(8-11)14-9-17(23)20-15-5-3-2-4-12(15)18(14)21-16/h2-8,21H,9H2,1H3,(H,19,22)(H,20,23)
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n/an/a 1.30E+3n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7324
PNG
(14-methoxy-6,8,18-triazatetracyclo[9.7.0.0^{2,7}.0...)
Show SMILES COc1ccc2[nH]c-3c(CC(=O)Nc4ncccc-34)c2c1
Show InChI InChI=1S/C16H13N3O2/c1-21-9-4-5-13-11(7-9)12-8-14(20)19-16-10(15(12)18-13)3-2-6-17-16/h2-7,18H,8H2,1H3,(H,17,19,20)
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n/an/a 9.00E+4n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7325
PNG
(2-(2-oxopropyl)-9-(trifluoromethyl)-7,12-dihydroin...)
Show SMILES CC(=O)Cc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)C(F)(F)F)-c2c1
Show InChI InChI=1S/C20H15F3N2O2/c1-10(26)6-11-2-4-17-15(7-11)19-14(9-18(27)24-17)13-8-12(20(21,22)23)3-5-16(13)25-19/h2-5,7-8,25H,6,9H2,1H3,(H,24,27)
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n/an/a 200n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7326
PNG
(14-chloro-6,8,18-triazatetracyclo[9.7.0.0^{2,7}.0^...)
Show SMILES Clc1ccc2[nH]c-3c(CC(=O)Nc4ncccc-34)c2c1
Show InChI InChI=1S/C15H10ClN3O/c16-8-3-4-12-10(6-8)11-7-13(20)19-15-9(14(11)18-12)2-1-5-17-15/h1-6,18H,7H2,(H,17,19,20)
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n/an/a 2.30E+4n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7327
PNG
(14-(trifluoromethyl)-6,8,18-triazatetracyclo[9.7.0...)
Show SMILES FC(F)(F)c1ccc2[nH]c-3c(CC(=O)Nc4ncccc-34)c2c1
Show InChI InChI=1S/C16H10F3N3O/c17-16(18,19)8-3-4-12-10(6-8)11-7-13(23)22-15-9(14(11)21-12)2-1-5-20-15/h1-6,21H,7H2,(H,20,22,23)
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PubMed
n/an/a 6.00E+3n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7328
PNG
(3-Methoxy-6-oxo-5,6,7,12-tetrahydro-indolo[3,2-d][...)
Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)C#N
Show InChI InChI=1S/C18H13N3O2/c1-23-11-3-4-12-16(7-11)20-17(22)8-14-13-6-10(9-19)2-5-15(13)21-18(12)14/h2-7,21H,8H2,1H3,(H,20,22)
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n/an/a 1.20E+3n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7329
PNG
(3-Methoxy-9-nitro-7,12-dihydro-indolo[3,2-d][1]ben...)
Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)[N+]([O-])=O
Show InChI InChI=1S/C17H13N3O4/c1-24-10-3-4-11-15(7-10)18-16(21)8-13-12-6-9(20(22)23)2-5-14(12)19-17(11)13/h2-7,19H,8H2,1H3,(H,18,21)
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n/an/a 1.00E+3n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7330
PNG
(2-Methoxy-9-nitro-7,12-dihydro-indolo[3,2-d][1]ben...)
Show SMILES COc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)[N+]([O-])=O)-c2c1
Show InChI InChI=1S/C17H13N3O4/c1-24-10-3-5-15-13(7-10)17-12(8-16(21)18-15)11-6-9(20(22)23)2-4-14(11)19-17/h2-7,19H,8H2,1H3,(H,18,21)
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n/an/a 80n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7331
PNG
(14-methyl-6,8,18-triazatetracyclo[9.7.0.0^{2,7}.0^...)
Show SMILES Cc1ccc2[nH]c-3c(CC(=O)Nc4ncccc-34)c2c1
Show InChI InChI=1S/C16H13N3O/c1-9-4-5-13-11(7-9)12-8-14(20)19-16-10(15(12)18-13)3-2-6-17-16/h2-7,18H,8H2,1H3,(H,17,19,20)
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n/an/a 2.00E+5n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7332
PNG
(7,12-Dihydro-pyrido[3 ,2 :4,5]pyrrolo[3,2-d][1]ben...)
Show SMILES O=C1Cc2c([nH]c3ncccc23)-c2ccccc2N1
Show InChI InChI=1S/C15H11N3O/c19-13-8-11-9-5-3-7-16-15(9)18-14(11)10-4-1-2-6-12(10)17-13/h1-7H,8H2,(H,16,18)(H,17,19)
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n/an/a 2.20E+3n/an/an/an/a7.230



Universitat Hamburg



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 22-36 (2004)


Article DOI: 10.1021/jm0308904
BindingDB Entry DOI: 10.7270/Q28050TR
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7392
PNG
(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Show SMILES O=C1Nc2ccccc2\C1=C1\Nc2ccccc2C1=O
Show InChI InChI=1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)/b14-13-
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n/an/a 1.00E+4n/an/an/an/a7.230



University of Athens



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 935-46 (2004)


Article DOI: 10.1021/jm031016d
BindingDB Entry DOI: 10.7270/Q20G3HB8
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7393
PNG
(3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...)
Show SMILES O=Nc1c([nH]c2ccccc12)C1C(=O)Nc2ccccc12
Show InChI InChI=1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,13,17H,(H,18,20)
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n/an/a 180n/an/an/an/a7.230



University of Athens



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 935-46 (2004)


Article DOI: 10.1021/jm031016d
BindingDB Entry DOI: 10.7270/Q20G3HB8
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1)


(Marthasterias glacialis (starfish))
BDBM7394
PNG
((2 Z,3 E)-Indirubin-3 -acetoxime | [(3E)-2-[(3Z)-2...)
Show SMILES CC(=O)ON=C1C(Nc2ccccc12)=C1C(=O)Nc2ccccc12
Show InChI InChI=1S/C18H13N3O3/c1-10(22)24-21-16-12-7-3-5-9-14(12)19-17(16)15-11-6-2-4-8-13(11)20-18(15)23/h2-9,19H,1H3,(H,20,23)
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n/an/a 1.20E+3n/an/an/an/a7.230



University of Athens



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 47: 935-46 (2004)


Article DOI: 10.1021/jm031016d
BindingDB Entry DOI: 10.7270/Q20G3HB8
More data for this
Ligand-Target Pair
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