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Found 650 of ph data with Target = 'E3 ubiquitin-protein ligase XIAP [241-356]'
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17336((2S)-2-{[(2S)-1-({2-[(1S)-1-aminoethyl]-1,3-oxazol...)
Affinity DataKd:  1.10E+4nMpH: 7.0 T: 2°CAssay Description:AVPC-badan can be displaced from the binding pocket of the protein by test compounds. As the dye is displaced from the binding pocket, the emission i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17340((2S,3R)-2-{[(2S)-1-({2-[(1S)-1-aminoethyl]-1,3-oxa...)
Affinity DataKd:  3.00E+5nMpH: 7.0 T: 2°CAssay Description:AVPC-badan can be displaced from the binding pocket of the protein by test compounds. As the dye is displaced from the binding pocket, the emission i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17339((2S)-2-{[(2S)-1-({2-[(1S)-1-aminoethyl]-1,3-oxazol...)
Affinity DataKd:  1.20E+5nMpH: 7.0 T: 2°CAssay Description:AVPC-badan can be displaced from the binding pocket of the protein by test compounds. As the dye is displaced from the binding pocket, the emission i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17338((2S)-2-{[(2S)-1-({2-[(1S)-1-aminoethyl]-1,3-oxazol...)
Affinity DataKd:  3.00E+4nMpH: 7.0 T: 2°CAssay Description:AVPC-badan can be displaced from the binding pocket of the protein by test compounds. As the dye is displaced from the binding pocket, the emission i...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17344((2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17347((3R,6S,9aR)-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-...)
Affinity DataKi:  270nM ΔG°:  -37.1kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17341((2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2...)
Affinity DataKi:  670nM ΔG°:  -34.9kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17345((3R,6S,9aR)-2,2-dimethyl-N-(3-methyl-1-phenyl-1H-p...)
Affinity DataKi:  770nM ΔG°:  -34.5kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17346((3R,6S,9aS)-2,2-dimethyl-N-(3-methyl-1-phenyl-1H-p...)
Affinity DataKi:  2.34E+3nM ΔG°:  -31.8kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17348((3R,6S,9aS)-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-...)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.2kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM17343((2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2...)
Affinity DataKi:  3.98E+4nM ΔG°:  -24.9kJ/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13166((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  12nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13186((2S)-2-amino-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl...)
Affinity DataKd:  1.50E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13168((2S)-N-[(1R)-2,3-dihydro-1H-inden-1-yl]-1-[(2S)-3,...)
Affinity DataKd:  29nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13169((2S)-N-[(1S)-2,3-dihydro-1H-inden-1-yl]-1-[(2S)-3,...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13170((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd: >500nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13171((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13172((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  47nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13173((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  167nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13174((2S,4S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamin...)
Affinity DataKd:  5nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13175((2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  16nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13176((2S,4S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamin...)
Affinity DataKd:  6nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13177((2S)-1-[(2S)-2-[(2S)-2-(dimethylamino)propanamido]...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13178((2S,4S)-1-[(2S)-2-[(2S)-2-(dimethylamino)propanami...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13179((2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(dimethylamino...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13180((2S)-1-[(2S)-3,3-dimethyl-2-[(2R)-2-(methylamino)p...)
Affinity DataKd: >1.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13181((2S)-2-amino-N-(5,7-dimethyl-1,8-naphthyridin-2-yl...)
Affinity DataKd:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13182((2S)-2-amino-N-[5-(4-butoxyphenyl)-1,3,4-thiadiazo...)
Affinity DataKd:  2.50E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13183((2S)-2-amino-N-(5-benzoyl-1H-1,3-benzodiazol-2-yl)...)
Affinity DataKd:  3.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13184((2S)-2-amino-N-[4-(4-chloro-3-methylphenyl)-1,3-th...)
Affinity DataKd:  3.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13185((2S)-2-amino-N-{5-methyl-4-[(2,4,6-trimethylphenyl...)
Affinity DataKd:  2.00E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13167((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  706nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26214((3S,6S,10aS)-6-[(2S)-2-aminopropanamido]-N-(diphen...)
Affinity DataKi:  14nM ΔG°:  -44.4kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26223((3S,6S,10aS)-6-[(2S)-2-(methylamino)propanamido]-5...)
Affinity DataKi:  14nM ΔG°:  -44.4kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26225((3S,6S,10aS)-N-[(1R)-2,3-dihydro-1H-inden-1-yl]-6-...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26207((2R,5S,8S)-8-[(2S)-2-(methylamino)propanamido]-7-o...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13152((2S)-1-[(2S)-2-[(2S)-2-aminobutanamido]-3-methylbu...)
Affinity DataKi:  24nM ΔG°:  -43.1kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13211((3S,6S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphenyl...)
Affinity DataKi:  25nM ΔG°:  -43.0kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13211((3S,6S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphenyl...)
Affinity DataKi:  25nM ΔG°:  -43.0kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26218((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(methyla...)
Affinity DataKi:  26nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13151((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...)
Affinity DataKi:  28nM ΔG°:  -42.7kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26206((2R,5S,8S)-N-(diphenylmethyl)-8-[(2S)-2-(methylami...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26215((3S,6S,10aS)-6-[(2S)-2-aminobutanamido]-N-(dipheny...)
Affinity DataKi:  39nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26217((3S,6S,10aS)-6-[(2S)-2-aminobutanamido]-N-[(S)-nap...)
Affinity DataKi:  47nM ΔG°:  -41.4kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26212((3S,6S,9aS)-6-[(2S)-2-aminopropanamido]-N-(dipheny...)
Affinity DataKi:  60nM ΔG°:  -40.8kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13212((3S,6S,9aS)-N-(diphenylmethyl)-6-[(2S)-2-(methylam...)
Affinity DataKi:  61nM ΔG°:  -40.8kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13212((3S,6S,9aS)-N-(diphenylmethyl)-6-[(2S)-2-(methylam...)
Affinity DataKi:  61nM ΔG°:  -40.8kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13212((3S,6S,9aS)-N-(diphenylmethyl)-6-[(2S)-2-(methylam...)
Affinity DataKi:  61nM ΔG°:  -40.8kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM26219((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(methyla...)
Affinity DataKi:  67nM ΔG°:  -40.5kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Princeton University

LigandPNGBDBM13155((2S)-1-[(2S)-2-[(2S)-2-aminobutanamido]-3-methylbu...)
Affinity DataKi:  81nM ΔG°:  -40.1kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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