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Compile Data Set for Download or QSAR

Found 5 hits of ph data with Target = 'Ephrin type-A receptor 4 ligand binding domain (EphA4-LBD)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-A receptor 4 ligand binding domain (EphA4-LBD)


(Homo sapiens (Human))
BDBM223300
PNG
(EphA4-LBC inhibitor, Compound 22)
Show SMILES NCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C42H44ClN9O6/c43-28-7-5-24(6-8-28)17-35(52-42(58)37(49-38(54)11-14-44)20-27-23-48-33-10-9-29(53)21-31(27)33)41(57)51-36(18-25-12-15-46-16-13-25)40(56)50-34(39(45)55)19-26-22-47-32-4-2-1-3-30(26)32/h1-10,12-13,15-16,21-23,34-37,47-48,53H,11,14,17-20,44H2,(H2,45,55)(H,49,54)(H,50,56)(H,51,57)(H,52,58)/t34-,35+,36+,37+/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.20E+3n/an/an/a6.527



Sanford-Burnham-Prebys Medical Discovery Institute



Assay Description
The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...


Cell Chem Biol 24: 293-305 (2017)


Article DOI: 10.1016/j.chembiol.2017.01.006
BindingDB Entry DOI: 10.7270/Q2GX49FB
More data for this
Ligand-Target Pair
Ephrin type-A receptor 4 ligand binding domain (EphA4-LBD)


(Homo sapiens (Human))
BDBM223305
PNG
(123C2)
Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C42H45ClN8O5/c43-30-9-7-26(8-10-30)20-37(51-42(56)38(49-39(53)6-3-16-44)22-29-25-48-35-12-11-31(52)23-33(29)35)41(55)50-36(21-27-13-17-45-18-14-27)40(54)46-19-15-28-24-47-34-5-2-1-4-32(28)34/h1-2,4-5,7-14,17-18,23-25,36-38,47-48,52H,3,6,15-16,19-22,44H2,(H,46,54)(H,49,53)(H,50,55)(H,51,56)/t36-,37-,38-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.10E+3n/an/an/a6.527



Sanford-Burnham-Prebys Medical Discovery Institute



Assay Description
The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...


Cell Chem Biol 24: 293-305 (2017)


Article DOI: 10.1016/j.chembiol.2017.01.006
BindingDB Entry DOI: 10.7270/Q2GX49FB
More data for this
Ligand-Target Pair
Ephrin type-A receptor 4 ligand binding domain (EphA4-LBD)


(Homo sapiens (Human))
BDBM223311
PNG
(123C4)
Show SMILES COc1ccc2[nH]cc(CCNC(=O)[C@H](Cc3ccncc3)NC(=O)[C@H](Cc3ccc(Cl)cc3)NC(=O)[C@H](Cc3c[nH]c4ccc(O)cc34)NC(=O)CCCN)c2c1
Show InChI InChI=1S/C43H47ClN8O6/c1-58-32-9-11-36-34(23-32)28(24-48-36)14-18-47-41(55)37(20-27-12-16-46-17-13-27)51-42(56)38(19-26-4-6-30(44)7-5-26)52-43(57)39(50-40(54)3-2-15-45)21-29-25-49-35-10-8-31(53)22-33(29)35/h4-13,16-17,22-25,37-39,48-49,53H,2-3,14-15,18-21,45H2,1H3,(H,47,55)(H,50,54)(H,51,56)(H,52,57)/t37-,38-,39-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 420n/an/an/a6.527



Sanford-Burnham-Prebys Medical Discovery Institute



Assay Description
The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...


Cell Chem Biol 24: 293-305 (2017)


Article DOI: 10.1016/j.chembiol.2017.01.006
BindingDB Entry DOI: 10.7270/Q2GX49FB
More data for this
Ligand-Target Pair
Ephrin type-A receptor 4 ligand binding domain (EphA4-LBD)


(Homo sapiens (Human))
BDBM223310
PNG
(123C7)
Show SMILES COc1ccc2c(CCNC(=O)[C@H](Cc3ccncc3)NC(=O)[C@H](Cc3ccc(Cl)cc3)NC(=O)[C@H](Cc3c[nH]c4ccc(O)cc34)NC(=O)CCCN)c[nH]c2c1
Show InChI InChI=1S/C43H47ClN8O6/c1-58-32-9-10-33-28(24-49-36(33)23-32)14-18-47-41(55)37(20-27-12-16-46-17-13-27)51-42(56)38(19-26-4-6-30(44)7-5-26)52-43(57)39(50-40(54)3-2-15-45)21-29-25-48-35-11-8-31(53)22-34(29)35/h4-13,16-17,22-25,37-39,48-49,53H,2-3,14-15,18-21,45H2,1H3,(H,47,55)(H,50,54)(H,51,56)(H,52,57)/t37-,38-,39-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 540n/an/an/a6.527



Sanford-Burnham-Prebys Medical Discovery Institute



Assay Description
The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...


Cell Chem Biol 24: 293-305 (2017)


Article DOI: 10.1016/j.chembiol.2017.01.006
BindingDB Entry DOI: 10.7270/Q2GX49FB
More data for this
Ligand-Target Pair
Ephrin type-A receptor 4 ligand binding domain (EphA4-LBD)


(Homo sapiens (Human))
BDBM223308
PNG
(123C5)
Show SMILES NCCCC(=O)N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C42H45ClN8O6/c43-29-5-3-25(4-6-29)18-37(51-42(57)38(49-39(54)2-1-14-44)20-28-24-48-35-10-8-31(53)22-33(28)35)41(56)50-36(19-26-11-15-45-16-12-26)40(55)46-17-13-27-23-47-34-9-7-30(52)21-32(27)34/h3-12,15-16,21-24,36-38,47-48,52-53H,1-2,13-14,17-20,44H2,(H,46,55)(H,49,54)(H,50,56)(H,51,57)/t36-,37-,38-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 2.20E+3n/an/an/a6.527



Sanford-Burnham-Prebys Medical Discovery Institute



Assay Description
The purified EphA proteins (EphA4-LBD, EphA3-LBD, and EphA2-LBD) were dissolved in 50 mM potassium phosphate buffer (pH 6.5) containing 100 mM NaCl. ...


Cell Chem Biol 24: 293-305 (2017)


Article DOI: 10.1016/j.chembiol.2017.01.006
BindingDB Entry DOI: 10.7270/Q2GX49FB
More data for this
Ligand-Target Pair