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Compile Data Set for Download or QSAR

Found 2 hits of ph data with Target = 'Estrogen-Related Receptor, alpha'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Estrogen-Related Receptor, alpha


(Homo sapiens)
BDBM22421
PNG
((cyclohexylmethyl)[(1-phenyl-1H-indol-3-yl)methyl]...)
Show SMILES C(NCc1cn(-c2ccccc2)c2ccccc12)C1CCCCC1
Show InChI InChI=1S/C22H26N2/c1-3-9-18(10-4-1)15-23-16-19-17-24(20-11-5-2-6-12-20)22-14-8-7-13-21(19)22/h2,5-8,11-14,17-18,23H,1,3-4,9-10,15-16H2
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/a7.520



Novartis



Assay Description
The IC50s of compounds were determined in the FRET assay, which was conducted as time-resolved measurement (TR-FRET) in a 1536 well plate format. The...


J Biol Chem 282: 23231-9 (2007)


Article DOI: 10.1074/jbc.M703337200
BindingDB Entry DOI: 10.7270/Q21N7ZFJ
More data for this
Ligand-Target Pair
Estrogen-Related Receptor, alpha


(Homo sapiens)
BDBM22420
PNG
((cyclohexylmethyl)({[1-(4-methylphenyl)-1H-indol-3...)
Show SMILES Cc1ccc(cc1)-n1cc(CNCC2CCCCC2)c2ccccc12
Show InChI InChI=1S/C23H28N2/c1-18-11-13-21(14-12-18)25-17-20(22-9-5-6-10-23(22)25)16-24-15-19-7-3-2-4-8-19/h5-6,9-14,17,19,24H,2-4,7-8,15-16H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

DrugBank
MMDB
PDB
Article
PubMed
n/an/a 190n/an/an/an/a7.520



Novartis



Assay Description
The IC50s of compounds were determined in the FRET assay, which was conducted as time-resolved measurement (TR-FRET) in a 1536 well plate format. The...


J Biol Chem 282: 23231-9 (2007)


Article DOI: 10.1074/jbc.M703337200
BindingDB Entry DOI: 10.7270/Q21N7ZFJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)