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Compile Data Set for Download or QSAR

Found 2 hits of ph data with Target = 'General receptor of phosphoinositides 1 (GRP1)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
General receptor of phosphoinositides 1 (GRP1)


(Homo sapiens (Human))
BDBM112785
PNG
(US8628961, DM-PIT-1)
Show SMILES Cc1cc(C)cc(c1)C(=O)NC(=S)Nc1cc(ccc1O)[N+]([O-])=O
Show InChI InChI=1S/C16H15N3O4S/c1-9-5-10(2)7-11(6-9)15(21)18-16(24)17-13-8-12(19(22)23)3-4-14(13)20/h3-8,20H,1-2H3,(H2,17,18,21,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
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PC cid
PC sid
UniChem

Similars

n/an/a 3.55E+4n/an/an/an/a7.525



Tufts University; Council of Scientific and Industrial Research

US Patent


Assay Description
In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...


US Patent US8628961 (2014)


BindingDB Entry DOI: 10.7270/Q2MG7N5S
More data for this
Ligand-Target Pair
General receptor of phosphoinositides 1 (GRP1)


(Homo sapiens (Human))
BDBM112784
PNG
(US8628961, PIT-1)
Show SMILES Oc1c(Cl)cc(cc1NC(=S)NC(=O)c1ccccc1)[N+]([O-])=O
Show InChI InChI=1S/C14H10ClN3O4S/c15-10-6-9(18(21)22)7-11(12(10)19)16-14(23)17-13(20)8-4-2-1-3-5-8/h1-7,19H,(H2,16,17,20,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

n/an/a 4.03E+4n/an/an/an/a7.525



Tufts University; Council of Scientific and Industrial Research

US Patent


Assay Description
In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...


US Patent US8628961 (2014)


BindingDB Entry DOI: 10.7270/Q2MG7N5S
More data for this
Ligand-Target Pair