BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 117 hits of ph data with Target = 'Glucocorticoid receptor'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18193
PNG
(1-ethyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinoli...)
Show SMILES CCN1CCOc2cc3[nH]c(=O)cc(c3cc12)C(F)(F)F
Show InChI InChI=1S/C14H13F3N2O2/c1-2-19-3-4-21-12-7-10-8(5-11(12)19)9(14(15,16)17)6-13(20)18-10/h5-7H,2-4H2,1H3,(H,18,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
8.10E+3 -27.0n/an/an/an/an/a7.44



Ligand Pharmaceuticals Inc.



Assay Description
The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...


J Med Chem 50: 2486-96 (2007)


Article DOI: 10.1021/jm061329j
BindingDB Entry DOI: 10.7270/Q20R9MNK
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18198
PNG
(1-(cyclopropylmethyl)-9-(trifluoromethyl)-1H,2H,3H...)
Show SMILES FC(F)(F)c1cc(=O)[nH]c2cc3OCCN(CC4CC4)c3cc12
Show InChI InChI=1S/C16H15F3N2O2/c17-16(18,19)11-6-15(22)20-12-7-14-13(5-10(11)12)21(3-4-23-14)8-9-1-2-9/h5-7,9H,1-4,8H2,(H,20,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
8.80E+3 -26.8n/an/an/an/an/a7.44



Ligand Pharmaceuticals Inc.



Assay Description
The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...


J Med Chem 50: 2486-96 (2007)


Article DOI: 10.1021/jm061329j
BindingDB Entry DOI: 10.7270/Q20R9MNK
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18197
PNG
(1-(2,2,2-trifluoroethyl)-9-(trifluoromethyl)-1H,2H...)
Show SMILES FC(F)(F)CN1CCOc2cc3[nH]c(=O)cc(c3cc12)C(F)(F)F
Show InChI InChI=1S/C14H10F6N2O2/c15-13(16,17)6-22-1-2-24-11-5-9-7(3-10(11)22)8(14(18,19)20)4-12(23)21-9/h3-5H,1-2,6H2,(H,21,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
9.20E+3 -26.7n/an/an/an/an/a7.44



Ligand Pharmaceuticals Inc.



Assay Description
The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...


J Med Chem 50: 2486-96 (2007)


Article DOI: 10.1021/jm061329j
BindingDB Entry DOI: 10.7270/Q20R9MNK
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18706
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(propylsulfany...)
Show SMILES CCCSCC1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC
Show InChI InChI=1S/C22H27NOS/c1-5-12-25-15-17-14-22(2,3)23-20-11-10-16(13-19(17)20)18-8-6-7-9-21(18)24-4/h6-11,13-14,23H,5,12,15H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.02E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18707
PNG
(4-[(cyclopentylsulfanyl)methyl]-6-(2-methoxyphenyl...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSC3CCCC3)c2c1
Show InChI InChI=1S/C24H29NOS/c1-24(2)15-18(16-27-19-8-4-5-9-19)21-14-17(12-13-22(21)25-24)20-10-6-7-11-23(20)26-3/h6-7,10-15,19,25H,4-5,8-9,16H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 548n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18708
PNG
(4-[(cyclohexylsulfanyl)methyl]-6-(2-methoxyphenyl)...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSC3CCCCC3)c2c1
Show InChI InChI=1S/C25H31NOS/c1-25(2)16-19(17-28-20-9-5-4-6-10-20)22-15-18(13-14-23(22)26-25)21-11-7-8-12-24(21)27-3/h7-8,11-16,20,26H,4-6,9-10,17H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 371n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18709
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-methylbuty...)
Show SMILES CCC(C)CSCC1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC
Show InChI InChI=1S/C24H31NOS/c1-6-17(2)15-27-16-19-14-24(3,4)25-22-12-11-18(13-21(19)22)20-9-7-8-10-23(20)26-5/h7-14,17,25H,6,15-16H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 303n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18710
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(3-methylbuty...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSCCC(C)C)c2c1
Show InChI InChI=1S/C24H31NOS/c1-17(2)12-13-27-16-19-15-24(3,4)25-22-11-10-18(14-21(19)22)20-8-6-7-9-23(20)26-5/h6-11,14-15,17,25H,12-13,16H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 703n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18711
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(phenylsulfany...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSc3ccccc3)c2c1
Show InChI InChI=1S/C25H25NOS/c1-25(2)16-19(17-28-20-9-5-4-6-10-20)22-15-18(13-14-23(22)26-25)21-11-7-8-12-24(21)27-3/h4-16,26H,17H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 804n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18712
PNG
(4-[(benzylsulfanyl)methyl]-6-(2-methoxyphenyl)-2,2...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSCc3ccccc3)c2c1
Show InChI InChI=1S/C26H27NOS/c1-26(2)16-21(18-29-17-19-9-5-4-6-10-19)23-15-20(13-14-24(23)27-26)22-11-7-8-12-25(22)28-3/h4-16,27H,17-18H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18713
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-phenylethy...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSCCc3ccccc3)c2c1
Show InChI InChI=1S/C27H29NOS/c1-27(2)18-22(19-30-16-15-20-9-5-4-6-10-20)24-17-21(13-14-25(24)28-27)23-11-7-8-12-26(23)29-3/h4-14,17-18,28H,15-16,19H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 194n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18714
PNG
(4-{[(4-chlorophenyl)sulfanyl]methyl}-6-(2-methoxyp...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSc3ccc(Cl)cc3)c2c1
Show InChI InChI=1S/C25H24ClNOS/c1-25(2)15-18(16-29-20-11-9-19(26)10-12-20)22-14-17(8-13-23(22)27-25)21-6-4-5-7-24(21)28-3/h4-15,27H,16H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 800n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18715
PNG
(1-({[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroq...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSC(C)=O)c2c1
Show InChI InChI=1S/C21H23NO2S/c1-14(23)25-13-16-12-21(2,3)22-19-10-9-15(11-18(16)19)17-7-5-6-8-20(17)24-4/h5-12,22H,13H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18716
PNG
(6-(2-methoxyphenyl)-2,2,4-trimethyl-1,2-dihydroqui...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C)c2c1
Show InChI InChI=1S/C19H21NO/c1-13-12-19(2,3)20-17-10-9-14(11-16(13)17)15-7-5-6-8-18(15)21-4/h5-12,20H,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18717
PNG
(6-(2-fluorophenyl)-2,2-dimethyl-4-[(prop-2-en-1-yl...)
Show SMILES CC1(C)Nc2ccc(cc2C(CSCC=C)=C1)-c1ccccc1F
Show InChI InChI=1S/C21H22FNS/c1-4-11-24-14-16-13-21(2,3)23-20-10-9-15(12-18(16)20)17-7-5-6-8-19(17)22/h4-10,12-13,23H,1,11,14H2,2-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18718
PNG
(6-(3-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Show SMILES COc1cccc(c1)-c1ccc2NC(C)(C)C=C(CSCC=C)c2c1
Show InChI InChI=1S/C22H25NOS/c1-5-11-25-15-18-14-22(2,3)23-21-10-9-17(13-20(18)21)16-7-6-8-19(12-16)24-4/h5-10,12-14,23H,1,11,15H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18719
PNG
(6-(5-fluoro-2-methoxyphenyl)-2,2-dimethyl-4-[(prop...)
Show SMILES COc1ccc(F)cc1-c1ccc2NC(C)(C)C=C(CSCC=C)c2c1
Show InChI InChI=1S/C22H24FNOS/c1-5-10-26-14-16-13-22(2,3)24-20-8-6-15(11-18(16)20)19-12-17(23)7-9-21(19)25-4/h5-9,11-13,24H,1,10,14H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 190n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18720
PNG
(2-chloro-3-{2,2-dimethyl-4-[(prop-2-en-1-ylsulfany...)
Show SMILES CC1(C)Nc2ccc(cc2C(CSCC=C)=C1)-c1cccc(O)c1Cl
Show InChI InChI=1S/C21H22ClNOS/c1-4-10-25-13-15-12-21(2,3)23-18-9-8-14(11-17(15)18)16-6-5-7-19(24)20(16)22/h4-9,11-12,23-24H,1,10,13H2,2-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 129n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18721
PNG
(6-(5-fluoro-2-methoxyphenyl)-2,2-dimethyl-4-{[(2-p...)
Show SMILES COc1ccc(F)cc1-c1ccc2NC(C)(C)C=C(CSCCc3ccccc3)c2c1
Show InChI InChI=1S/C27H28FNOS/c1-27(2)17-21(18-31-14-13-19-7-5-4-6-8-19)23-15-20(9-11-25(23)29-27)24-16-22(28)10-12-26(24)30-3/h4-12,15-17,29H,13-14,18H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 84n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18722
PNG
(2-chloro-3-(2,2-dimethyl-4-{[(2-phenylethyl)sulfan...)
Show SMILES CC1(C)Nc2ccc(cc2C(CSCCc2ccccc2)=C1)-c1cccc(O)c1Cl
Show InChI InChI=1S/C26H26ClNOS/c1-26(2)16-20(17-30-14-13-18-7-4-3-5-8-18)22-15-19(11-12-23(22)28-26)21-9-6-10-24(29)25(21)27/h3-12,15-16,28-29H,13-14,17H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 220n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18724
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-ene-1-...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CS(=O)CC=C)c2c1
Show InChI InChI=1S/C22H25NO2S/c1-5-12-26(24)15-17-14-22(2,3)23-20-11-10-16(13-19(17)20)18-8-6-7-9-21(18)25-4/h5-11,13-14,23H,1,12,15H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18705
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSCC=C)c2c1
Show InChI InChI=1S/C22H25NOS/c1-5-12-25-15-17-14-22(2,3)23-20-11-10-16(13-19(17)20)18-8-6-7-9-21(18)24-4/h5-11,13-14,23H,1,12,15H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 360n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18725
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)SCC=C)c2c1
Show InChI InChI=1S/C23H27NOS/c1-6-13-26-16(2)20-15-23(3,4)24-21-12-11-17(14-19(20)21)18-9-7-8-10-22(18)25-5/h6-12,14-16,24H,1,13H2,2-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 116n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18704
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(COCC=C)c2c1
Show InChI InChI=1S/C22H25NO2/c1-5-12-25-15-17-14-22(2,3)23-20-11-10-16(13-19(17)20)18-8-6-7-9-21(18)24-4/h5-11,13-14,23H,1,12,15H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18728
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Show SMILES CCC(OCC=C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC
Show InChI InChI=1S/C24H29NO2/c1-6-14-27-22(7-2)20-16-24(3,4)25-21-13-12-17(15-19(20)21)18-10-8-9-11-23(18)26-5/h6,8-13,15-16,22,25H,1,7,14H2,2-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 355n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18729
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[2-methyl-1-(pr...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(OCC=C)C(C)C)c2c1
Show InChI InChI=1S/C25H31NO2/c1-7-14-28-24(17(2)3)21-16-25(4,5)26-22-13-12-18(15-20(21)22)19-10-8-9-11-23(19)27-6/h7-13,15-17,24,26H,1,14H2,2-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 710n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18730
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Show SMILES CCCC(OCC=C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC
Show InChI InChI=1S/C25H31NO2/c1-6-10-24(28-15-7-2)21-17-25(3,4)26-22-14-13-18(16-20(21)22)19-11-8-9-12-23(19)27-5/h7-9,11-14,16-17,24,26H,2,6,10,15H2,1,3-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18731
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(CC=C)OCC=C)c2c1
Show InChI InChI=1S/C25H29NO2/c1-6-10-24(28-15-7-2)21-17-25(3,4)26-22-14-13-18(16-20(21)22)19-11-8-9-12-23(19)27-5/h6-9,11-14,16-17,24,26H,1-2,10,15H2,3-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18732
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[phenyl(prop-2-...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(OCC=C)c3ccccc3)c2c1
Show InChI InChI=1S/C28H29NO2/c1-5-17-31-27(20-11-7-6-8-12-20)24-19-28(2,3)29-25-16-15-21(18-23(24)25)22-13-9-10-14-26(22)30-4/h5-16,18-19,27,29H,1,17H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18733
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[2-phenyl-1-(pr...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(Cc3ccccc3)OCC=C)c2c1
Show InChI InChI=1S/C29H31NO2/c1-5-17-32-28(18-21-11-7-6-8-12-21)25-20-29(2,3)30-26-16-15-22(19-24(25)26)23-13-9-10-14-27(23)31-4/h5-16,19-20,28,30H,1,17-18H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18734
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[3-phenyl-1-(pr...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(CCc3ccccc3)OCC=C)c2c1
Show InChI InChI=1S/C30H33NO2/c1-5-19-33-29(18-15-22-11-7-6-8-12-22)26-21-30(2,3)31-27-17-16-23(20-25(26)27)24-13-9-10-14-28(24)32-4/h5-14,16-17,20-21,29,31H,1,15,18-19H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18735
PNG
(4-(1-methoxyethyl)-6-(2-methoxyphenyl)-2,2-dimethy...)
Show SMILES COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC
Show InChI InChI=1S/C21H25NO2/c1-14(23-4)18-13-21(2,3)22-19-11-10-15(12-17(18)19)16-8-6-7-9-20(16)24-5/h6-14,22H,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.06E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18736
PNG
(4-{1-[(2E)-but-2-en-1-yloxy]ethyl}-6-(2-methoxyphe...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OC\C=C\C)c2c1
Show InChI InChI=1S/C24H29NO2/c1-6-7-14-27-17(2)21-16-24(3,4)25-22-13-12-18(15-20(21)22)19-10-8-9-11-23(19)26-5/h6-13,15-17,25H,14H2,1-5H3/b7-6+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 210n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18737
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(3-methylbu...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCC=C(C)C)c2c1
Show InChI InChI=1S/C25H31NO2/c1-17(2)13-14-28-18(3)22-16-25(4,5)26-23-12-11-19(15-21(22)23)20-9-7-8-10-24(20)27-6/h7-13,15-16,18,26H,14H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 395n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18738
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(2E)-pent-2...)
Show SMILES CC\C=C\COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC
Show InChI InChI=1S/C25H31NO2/c1-6-7-10-15-28-18(2)22-17-25(3,4)26-23-14-13-19(16-21(22)23)20-11-8-9-12-24(20)27-5/h7-14,16-18,26H,6,15H2,1-5H3/b10-7+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 565n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18739
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-(1-{[(2E)-3-phe...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OC\C=C\c3ccccc3)c2c1
Show InChI InChI=1S/C29H31NO2/c1-21(32-18-10-13-22-11-6-5-7-12-22)26-20-29(2,3)30-27-17-16-23(19-25(26)27)24-14-8-9-15-28(24)31-4/h5-17,19-21,30H,18H2,1-4H3/b13-10+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 980n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18740
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(3-phenylpro...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCCCc3ccccc3)c2c1
Show InChI InChI=1S/C29H33NO2/c1-21(32-18-10-13-22-11-6-5-7-12-22)26-20-29(2,3)30-27-17-16-23(19-25(26)27)24-14-8-9-15-28(24)31-4/h5-9,11-12,14-17,19-21,30H,10,13,18H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 260n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18741
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(2-phenyleth...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCCc3ccccc3)c2c1
Show InChI InChI=1S/C28H31NO2/c1-20(31-17-16-21-10-6-5-7-11-21)25-19-28(2,3)29-26-15-14-22(18-24(25)26)23-12-8-9-13-27(23)30-4/h5-15,18-20,29H,16-17H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 405n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18742
PNG
(4-{1-[2-(2-chlorophenyl)ethoxy]ethyl}-6-(2-methoxy...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCCc3ccccc3Cl)c2c1
Show InChI InChI=1S/C28H30ClNO2/c1-19(32-16-15-20-9-5-7-11-25(20)29)24-18-28(2,3)30-26-14-13-21(17-23(24)26)22-10-6-8-12-27(22)31-4/h5-14,17-19,30H,15-16H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 290n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18743
PNG
(4-{1-[2-(3-chlorophenyl)ethoxy]ethyl}-6-(2-methoxy...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCCc3cccc(Cl)c3)c2c1
Show InChI InChI=1S/C28H30ClNO2/c1-19(32-15-14-20-8-7-9-22(29)16-20)25-18-28(2,3)30-26-13-12-21(17-24(25)26)23-10-5-6-11-27(23)31-4/h5-13,16-19,30H,14-15H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 275n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18744
PNG
(4-{1-[2-(4-chlorophenyl)ethoxy]ethyl}-6-(2-methoxy...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCCc3ccc(Cl)cc3)c2c1
Show InChI InChI=1S/C28H30ClNO2/c1-19(32-16-15-20-9-12-22(29)13-10-20)25-18-28(2,3)30-26-14-11-21(17-24(25)26)23-7-5-6-8-27(23)31-4/h5-14,17-19,30H,15-16H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 185n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18745
PNG
(4-[1-(2-cyclohexylethoxy)ethyl]-6-(2-methoxyphenyl...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCCC3CCCCC3)c2c1
Show InChI InChI=1S/C28H37NO2/c1-20(31-17-16-21-10-6-5-7-11-21)25-19-28(2,3)29-26-15-14-22(18-24(25)26)23-12-8-9-13-27(23)30-4/h8-9,12-15,18-21,29H,5-7,10-11,16-17H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 400n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18719
PNG
(6-(5-fluoro-2-methoxyphenyl)-2,2-dimethyl-4-[(prop...)
Show SMILES COc1ccc(F)cc1-c1ccc2NC(C)(C)C=C(CSCC=C)c2c1
Show InChI InChI=1S/C22H24FNOS/c1-5-10-26-14-16-13-22(2,3)24-20-8-6-15(11-18(16)20)19-12-17(23)7-9-21(19)25-4/h5-9,11-13,24H,1,10,14H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 190n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18713
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-phenylethy...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSCCc3ccccc3)c2c1
Show InChI InChI=1S/C27H29NOS/c1-27(2)18-22(19-30-16-15-20-9-5-4-6-10-20)24-17-21(13-14-25(24)28-27)23-11-7-8-12-26(23)29-3/h4-14,17-18,28H,15-16,19H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 194n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18721
PNG
(6-(5-fluoro-2-methoxyphenyl)-2,2-dimethyl-4-{[(2-p...)
Show SMILES COc1ccc(F)cc1-c1ccc2NC(C)(C)C=C(CSCCc3ccccc3)c2c1
Show InChI InChI=1S/C27H28FNOS/c1-27(2)17-21(18-31-14-13-19-7-5-4-6-8-19)23-15-20(9-11-25(23)29-27)24-16-22(28)10-12-26(24)30-3/h4-12,15-17,29H,13-14,18H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 84n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18746
PNG
(6-(5-fluoro-2-methoxyphenyl)-2,2-dimethyl-4-[1-(pr...)
Show SMILES COc1ccc(F)cc1-c1ccc2NC(C)(C)C=C(C(C)OCC=C)c2c1
Show InChI InChI=1S/C23H26FNO2/c1-6-11-27-15(2)20-14-23(3,4)25-21-9-7-16(12-19(20)21)18-13-17(24)8-10-22(18)26-5/h6-10,12-15,25H,1,11H2,2-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 34n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18705
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSCC=C)c2c1
Show InChI InChI=1S/C22H25NOS/c1-5-12-25-15-17-14-22(2,3)23-20-11-10-16(13-19(17)20)18-8-6-7-9-21(18)24-4/h5-11,13-14,23H,1,12,15H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 360n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18704
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(COCC=C)c2c1
Show InChI InChI=1S/C22H25NO2/c1-5-12-25-15-17-14-22(2,3)23-20-11-10-16(13-19(17)20)18-8-6-7-9-21(18)24-4/h5-11,13-14,23H,1,12,15H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18702
PNG
(dihydroquinoline compound, 14 | {[6-(2-methoxyphen...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CNCC=C)c2c1
Show InChI InChI=1S/C22H26N2O/c1-5-12-23-15-17-14-22(2,3)24-20-11-10-16(13-19(17)20)18-8-6-7-9-21(18)25-4/h5-11,13-14,23-24H,1,12,15H2,2-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 16: 1549-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.12.043
BindingDB Entry DOI: 10.7270/Q25B00RG
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM18727
PNG
(6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...)
Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OCC=C)c2c1
Show InChI InChI=1S/C23H27NO2/c1-6-13-26-16(2)20-15-23(3,4)24-21-12-11-17(14-19(20)21)18-9-7-8-10-22(18)25-5/h6-12,14-16,24H,1,13H2,2-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 116n/an/an/an/a7.422



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.


Bioorg Med Chem Lett 17: 5091-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.021
BindingDB Entry DOI: 10.7270/Q21J981M
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 117 total )  |  Next  |  Last  >>
Jump to: