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Compile Data Set for Download or QSAR

Found 1 hit of ph data with Target = 'Glutaredoxin-1 (GRX-1)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaredoxin-1 (GRX-1)


(Homo sapiens (Human))
BDBM240789
PNG
(2-AAPA)
Show SMILES CC(=O)NC(CSC(=S)Nc1ccc(NC(=S)SCC(NC(C)=O)C(O)=O)cc1)C(O)=O
Show InChI InChI=1S/C18H22N4O6S4/c1-9(23)19-13(15(25)26)7-31-17(29)21-11-3-5-12(6-4-11)22-18(30)32-8-14(16(27)28)20-10(2)24/h3-6,13-14H,7-8H2,1-2H3,(H,19,23)(H,20,24)(H,21,29)(H,22,30)(H,25,26)(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
9.13E+4 -23.1n/an/an/an/an/a8.025



South Dakota State University



Assay Description
Human GRX-1 (0.25 unit/mL) was incubated at 25°C with increasing concentrations of 2-AAPA (25, 50, 100, and 200 μM) and BSA (1 mg/mL). Aliquots...


J Enzyme Inhib Med Chem 28: 456-62 (2013)


Article DOI: 10.3109/14756366.2011.649267
BindingDB Entry DOI: 10.7270/Q2NG4PHV
More data for this
Ligand-Target Pair