Compile Data Set for Download or QSAR

Found 97 hits of ph data with Target = 'Glycogen Phosphorylase (PYGL)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35338 (indole-2-carboxamide derivative, 3) Show SMILES OC1CCc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc12 Show InChI InChI=1S/C18H15ClN2O2/c19-12-2-5-15-11(7-12)9-16(21-15)18(23)20-13-3-4-14-10(8-13)1-6-17(14)22/h2-5,7-9,17,21-22H,1,6H2,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35640 (5-chloroindolecarboxamide, 15b) Show SMILES OCC(O)c1cnc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)s1 Show InChI InChI=1S/C14H12ClN3O3S/c15-8-1-2-9-7(3-8)4-10(17-9)13(21)18-14-16-5-12(22-14)11(20)6-19/h1-5,11,17,19-20H,6H2,(H,16,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35340 (indole-2-carboxamide derivative, 5c) Show SMILES OC1CCCCc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc12 Show InChI InChI=1S/C20H19ClN2O2/c21-14-5-8-17-13(9-14)11-18(23-17)20(25)22-15-6-7-16-12(10-15)3-1-2-4-19(16)24/h5-11,19,23-24H,1-4H2,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35341 (indole-2-carboxamide derivative, 7) Show SMILES Oc1cccc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc12 Show InChI InChI=1S/C19H13ClN2O2/c20-13-4-7-16-12(8-13)10-17(22-16)19(24)21-14-5-6-15-11(9-14)2-1-3-18(15)23/h1-10,22-23H,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35342 (cis-isomers | indole-2-carboxamide derivative, 9a) Show SMILES O[C@@H]1CCc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc2[C@@H]1O Show InChI InChI=1S/C19H17ClN2O3/c20-12-2-5-15-11(7-12)9-16(22-15)19(25)21-13-3-4-14-10(8-13)1-6-17(23)18(14)24/h2-5,7-9,17-18,22-24H,1,6H2,(H,21,25)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35343 (indole-2-carboxamide derivative, 9b | trans-isomer...) Show SMILES O[C@H]1CCc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc2[C@@H]1O Show InChI InChI=1S/C19H17ClN2O3/c20-12-2-5-15-11(7-12)9-16(22-15)19(25)21-13-3-4-14-10(8-13)1-6-17(23)18(14)24/h2-5,7-9,17-18,22-24H,1,6H2,(H,21,25)/t17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35344 (indole-2-carboxamide derivative, 12) Show SMILES CC1(C)CCc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc2C1O Show InChI InChI=1S/C21H21ClN2O2/c1-21(2)8-7-12-10-15(4-5-16(12)19(21)25)23-20(26)18-11-13-9-14(22)3-6-17(13)24-18/h3-6,9-11,19,24-25H,7-8H2,1-2H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35345 (indole-2-carboxamide derivative, 15) Show SMILES OC1c2ccc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)cc2CCC1(F)F Show InChI InChI=1S/C19H15ClF2N2O2/c20-12-1-4-15-11(7-12)9-16(24-15)18(26)23-13-2-3-14-10(8-13)5-6-19(21,22)17(14)25/h1-4,7-9,17,24-25H,5-6H2,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35346 ((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...) Show SMILES OC1CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C23H23ClFN3O3/c24-16-3-6-19-15(12-16)13-20(26-19)22(30)27-21(11-14-1-4-17(25)5-2-14)23(31)28-9-7-18(29)8-10-28/h1-6,12-13,18,21,26,29H,7-11H2,(H,27,30)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35350 (indole-2-carboxamide derivative, 25d) Show SMILES OC1c2ccc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)c(F)c2CCC1(F)F Show InChI InChI=1S/C19H14ClF3N2O2/c20-10-1-3-13-9(7-10)8-15(24-13)18(27)25-14-4-2-12-11(16(14)21)5-6-19(22,23)17(12)26/h1-4,7-8,17,24,26H,5-6H2,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35351 (indole-2-carboxamide derivative, 25e) Show SMILES OC1c2cc(F)c(NC(=O)c3cc4cc(Cl)ccc4[nH]3)c(F)c2CCC1(F)F Show InChI InChI=1S/C19H13ClF4N2O2/c20-9-1-2-13-8(5-9)6-14(25-13)18(28)26-16-12(21)7-11-10(15(16)22)3-4-19(23,24)17(11)27/h1-2,5-7,17,25,27H,3-4H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35352 (indole-2-carboxamide derivative, 25e (S-isomer)) Show SMILES O[C@H]1c2cc(F)c(NC(=O)c3cc4cc(Cl)ccc4[nH]3)c(F)c2CCC1(F)F Show InChI InChI=1S/C19H13ClF4N2O2/c20-9-1-2-13-8(5-9)6-14(25-13)18(28)26-16-12(21)7-11-10(15(16)22)3-4-19(23,24)17(11)27/h1-2,5-7,17,25,27H,3-4H2,(H,26,28)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35353 (indole-2-carboxamide derivative, 25e (R-isomer)) Show SMILES O[C@@H]1c2cc(F)c(NC(=O)c3cc4cc(Cl)ccc4[nH]3)c(F)c2CCC1(F)F Show InChI InChI=1S/C19H13ClF4N2O2/c20-9-1-2-13-8(5-9)6-14(25-13)18(28)26-16-12(21)7-11-10(15(16)22)3-4-19(23,24)17(11)27/h1-2,5-7,17,25,27H,3-4H2,(H,26,28)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35347 (indole-2-carboxamide derivative, 25a) Show SMILES COc1cc2C(O)C(F)(F)CCc2cc1NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C20H17ClF2N2O3/c1-28-17-9-13-10(4-5-20(22,23)18(13)26)7-15(17)25-19(27)16-8-11-6-12(21)2-3-14(11)24-16/h2-3,6-9,18,24,26H,4-5H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35348 (indole-2-carboxamide derivative, 25b) Show SMILES COc1c(NC(=O)c2cc3cc(Cl)ccc3[nH]2)ccc2C(O)C(F)(F)CCc12 Show InChI InChI=1S/C20H17ClF2N2O3/c1-28-17-12-6-7-20(22,23)18(26)13(12)3-5-15(17)25-19(27)16-9-10-8-11(21)2-4-14(10)24-16/h2-5,8-9,18,24,26H,6-7H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35349 (indole-2-carboxamide derivative, 25c) Show SMILES OC1c2cc(F)c(NC(=O)c3cc4cc(Cl)ccc4[nH]3)cc2CCC1(F)F Show InChI InChI=1S/C19H14ClF3N2O2/c20-11-1-2-14-10(5-11)7-16(24-14)18(27)25-15-6-9-3-4-19(22,23)17(26)12(9)8-13(15)21/h1-2,5-8,17,24,26H,3-4H2,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35617 (5-chloroindolecarboxamide, 2a) Show SMILES OCc1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C16H13ClN2O2/c17-12-3-6-14-11(7-12)8-15(19-14)16(21)18-13-4-1-10(9-20)2-5-13/h1-8,19-20H,9H2,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35618 (5-chloroindolecarboxamide, 2b) Show SMILES OCCc1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C17H15ClN2O2/c18-13-3-6-15-12(9-13)10-16(20-15)17(22)19-14-4-1-11(2-5-14)7-8-21/h1-6,9-10,20-21H,7-8H2,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35619 (5-chloroindolecarboxamide, 2c) Show SMILES OCCCc1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C18H17ClN2O2/c19-14-5-8-16-13(10-14)11-17(21-16)18(23)20-15-6-3-12(4-7-15)2-1-9-22/h3-8,10-11,21-22H,1-2,9H2,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35623 (5-chloroindolecarboxamide, 2g) Show SMILES OCC(CO)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C18H17ClN2O3/c19-14-3-6-16-12(7-14)8-17(21-16)18(24)20-15-4-1-11(2-5-15)13(9-22)10-23/h1-8,13,21-23H,9-10H2,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35624 (5-chloroindolecarboxamide, 2h) Show SMILES COCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C18H17ClN2O3/c1-24-10-17(22)11-2-5-14(6-3-11)20-18(23)16-9-12-8-13(19)4-7-15(12)21-16/h2-9,17,21-22H,10H2,1H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35625 (5-chloroindolecarboxamide, 2i) Show SMILES CC(C)(O)C(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C19H19ClN2O3/c1-19(2,25)17(23)11-3-6-14(7-4-11)21-18(24)16-10-12-9-13(20)5-8-15(12)22-16/h3-10,17,22-23,25H,1-2H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35346 ((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...) Show SMILES OC1CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C23H23ClFN3O3/c24-16-3-6-19-15(12-16)13-20(26-19)22(30)27-21(11-14-1-4-17(25)5-2-14)23(31)28-9-7-18(29)8-10-28/h1-6,12-13,18,21,26,29H,7-11H2,(H,27,30)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35626 (5-chloroindolecarboxamide, 9a) Show SMILES Cc1cc(ccc1NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(O)CO Show InChI InChI=1S/C18H17ClN2O3/c1-10-6-11(17(23)9-22)2-4-14(10)21-18(24)16-8-12-7-13(19)3-5-15(12)20-16/h2-8,17,20,22-23H,9H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35627 (5-chloroindolecarboxamide, 9b) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)c(F)c1 Show InChI InChI=1S/C17H14ClFN2O3/c18-11-2-4-13-10(5-11)7-15(20-13)17(24)21-14-3-1-9(6-12(14)19)16(23)8-22/h1-7,16,20,22-23H,8H2,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35628 (5-chloroindolecarboxamide, 9c) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)c(Cl)c1 Show InChI InChI=1S/C17H14Cl2N2O3/c18-11-2-4-13-10(5-11)7-15(20-13)17(24)21-14-3-1-9(6-12(14)19)16(23)8-22/h1-7,16,20,22-23H,8H2,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35629 (5-chloroindolecarboxamide, 9d) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)c(c1)C(F)(F)F Show InChI InChI=1S/C18H14ClF3N2O3/c19-11-2-4-13-10(5-11)7-15(23-13)17(27)24-14-3-1-9(16(26)8-25)6-12(14)18(20,21)22/h1-7,16,23,25-26H,8H2,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35620 (5-chloroindolecarboxamide, 2d) Show SMILES OCCc1ccccc1NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C17H15ClN2O2/c18-13-5-6-15-12(9-13)10-16(19-15)17(22)20-14-4-2-1-3-11(14)7-8-21/h1-6,9-10,19,21H,7-8H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35621 (5-chloroindolecarboxamide, 2e) Show SMILES OCCc1cccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)c1 Show InChI InChI=1S/C17H15ClN2O2/c18-13-4-5-15-12(9-13)10-16(20-15)17(22)19-14-3-1-2-11(8-14)6-7-21/h1-5,8-10,20-21H,6-7H2,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35622 (5-chloroindolecarboxamide, 2f) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 Show InChI InChI=1S/C17H15ClN2O3/c18-12-3-6-14-11(7-12)8-15(20-14)17(23)19-13-4-1-10(2-5-13)16(22)9-21/h1-8,16,20-22H,9H2,(H,19,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35630 (5-chloroindolecarboxamide, 9e) Show SMILES COc1cc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)ccc1C(O)CO Show InChI InChI=1S/C18H17ClN2O4/c1-25-17-8-12(3-4-13(17)16(23)9-22)20-18(24)15-7-10-6-11(19)2-5-14(10)21-15/h2-8,16,21-23H,9H2,1H3,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35631 (5-chloroindolecarboxamide, 9f) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1-c1ccccc1 Show InChI InChI=1S/C23H19ClN2O3/c24-16-6-9-20-15(10-16)11-21(26-20)23(29)25-17-7-8-18(22(28)13-27)19(12-17)14-4-2-1-3-5-14/h1-12,22,26-28H,13H2,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35632 (5-chloroindolecarboxamide, 9g) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1F Show InChI InChI=1S/C17H14ClFN2O3/c18-10-1-4-14-9(5-10)6-15(21-14)17(24)20-11-2-3-12(13(19)7-11)16(23)8-22/h1-7,16,21-23H,8H2,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35633 (5-chloroindolecarboxamide, 9h) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1C(F)(F)F Show InChI InChI=1S/C18H14ClF3N2O3/c19-10-1-4-14-9(5-10)6-15(24-14)17(27)23-11-2-3-12(16(26)8-25)13(7-11)18(20,21)22/h1-7,16,24-26H,8H2,(H,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35634 (5-chloroindolecarboxamide, 9i) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1[N+]([O-])=O Show InChI InChI=1S/C17H14ClN3O5/c18-10-1-4-13-9(5-10)6-14(20-13)17(24)19-11-2-3-12(16(23)8-22)15(7-11)21(25)26/h1-7,16,20,22-23H,8H2,(H,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35635 (5-chloroindolecarboxamide, 9j) Show SMILES Nc1cc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)ccc1C(O)CO Show InChI InChI=1S/C17H16ClN3O3/c18-10-1-4-14-9(5-10)6-15(21-14)17(24)20-11-2-3-12(13(19)7-11)16(23)8-22/h1-7,16,21-23H,8,19H2,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35636 (5-chloroindolecarboxamide, 13a) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)nc1 Show InChI InChI=1S/C16H14ClN3O3/c17-11-2-3-12-10(5-11)6-13(19-12)16(23)20-15-4-1-9(7-18-15)14(22)8-21/h1-7,14,19,21-22H,8H2,(H,18,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35637 (5-chloroindolecarboxamide, 13b) Show SMILES OCC(O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cn1 Show InChI InChI=1S/C16H14ClN3O3/c17-10-1-3-12-9(5-10)6-14(20-12)16(23)19-11-2-4-13(18-7-11)15(22)8-21/h1-7,15,20-22H,8H2,(H,19,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35638 (5-chloroindolecarboxamide, 13c) Show SMILES OCC(O)c1cnc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)cn1 Show InChI InChI=1S/C15H13ClN4O3/c16-9-1-2-10-8(3-9)4-11(19-10)15(23)20-14-6-17-12(5-18-14)13(22)7-21/h1-6,13,19,21-22H,7H2,(H,18,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35639 (5-chloroindolecarboxamide, 15a) Show SMILES OCC(O)c1csc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)n1 Show InChI InChI=1S/C14H12ClN3O3S/c15-8-1-2-9-7(3-8)4-10(16-9)13(21)18-14-17-11(6-22-14)12(20)5-19/h1-4,6,12,16,19-20H,5H2,(H,17,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 5452-64 (2008) Article DOI: 10.1016/j.bmc.2008.04.010 BindingDB Entry DOI: 10.7270/Q2J101H2
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM35339 (indole-2-carboxamide derivative, 5b) Show SMILES OC1CCCc2cc(NC(=O)c3cc4cc(Cl)ccc4[nH]3)ccc12 Show InChI InChI=1S/C19H17ClN2O2/c20-13-4-7-16-12(8-13)10-17(22-16)19(24)21-14-5-6-15-11(9-14)2-1-3-18(15)23/h4-10,18,22-23H,1-3H2,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	6.8	22
Astellas Pharma Inc.					Assay Description The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...				Bioorg Med Chem 16: 10001-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.021 BindingDB Entry DOI: 10.7270/Q2K072MF
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24361 (2,3-dichloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3...) Show SMILES Clc1sc2cc([nH]c2c1Cl)C(=O)NC1Cc2ccccc2NC1=O Show InChI InChI=1S/C16H11Cl2N3O2S/c17-12-13-11(24-14(12)18)6-10(19-13)16(23)21-9-5-7-3-1-2-4-8(7)20-15(9)22/h1-4,6,9,19H,5H2,(H,20,22)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24363 (2-chloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)...) Show SMILES Clc1cc2cc([nH]c2s1)C(=O)NC1Cc2ccccc2NC1=O Show InChI InChI=1S/C16H12ClN3O2S/c17-13-7-9-6-12(20-16(9)23-13)15(22)19-11-5-8-3-1-2-4-10(8)18-14(11)21/h1-4,6-7,11,20H,5H2,(H,18,21)(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24364 (2-chloro-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquino...) Show SMILES CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cc(Cl)sc2[nH]1 Show InChI InChI=1S/C17H14ClN3O2S/c1-21-13-5-3-2-4-9(13)6-12(17(21)23)19-15(22)11-7-10-8-14(18)24-16(10)20-11/h2-5,7-8,12,20H,6H2,1H3,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	223	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24365 (2-chloro-N-[1-(2-methoxyethyl)-2-oxo-1,2,3,4-tetra...) Show SMILES COCCN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cc(Cl)sc2[nH]1 Show InChI InChI=1S/C19H18ClN3O3S/c1-26-7-6-23-15-5-3-2-4-11(15)8-14(19(23)25)21-17(24)13-9-12-10-16(20)27-18(12)22-13/h2-5,9-10,14,22H,6-8H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24366 (2-chloro-N-{1-[2-(methylsulfanyl)ethyl]-2-oxo-1,2,...) Show SMILES CSCCN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cc(Cl)sc2[nH]1 Show InChI InChI=1S/C19H18ClN3O2S2/c1-26-7-6-23-15-5-3-2-4-11(15)8-14(19(23)25)21-17(24)13-9-12-10-16(20)27-18(12)22-13/h2-5,9-10,14,22H,6-8H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24367 (2-chloro-N-[1-(2-methanesulfinylethyl)-2-oxo-1,2,3...) Show SMILES CS(=O)CCN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cc(Cl)sc2[nH]1 Show InChI InChI=1S/C19H18ClN3O3S2/c1-28(26)7-6-23-15-5-3-2-4-11(15)8-14(19(23)25)21-17(24)13-9-12-10-16(20)27-18(12)22-13/h2-5,9-10,14,22H,6-8H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24368 (2-chloro-N-[1-(2-methanesulfonylethyl)-2-oxo-1,2,3...) Show SMILES CS(=O)(=O)CCN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cc(Cl)sc2[nH]1 Show InChI InChI=1S/C19H18ClN3O4S2/c1-29(26,27)7-6-23-15-5-3-2-4-11(15)8-14(19(23)25)21-17(24)13-9-12-10-16(20)28-18(12)22-13/h2-5,9-10,14,22H,6-8H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24369 (2-chloro-N-[2-oxo-1-(2-oxobutyl)-1,2,3,4-tetrahydr...) Show SMILES CCC(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cc(Cl)sc2[nH]1 Show InChI InChI=1S/C20H18ClN3O3S/c1-2-13(25)10-24-16-6-4-3-5-11(16)7-15(20(24)27)22-18(26)14-8-12-9-17(21)28-19(12)23-14/h3-6,8-9,15,23H,2,7,10H2,1H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (human))	BDBM24370 (2-[3-({2,3-dichloro-4H-thieno[3,2-b]pyrrole-5-}ami...) Show SMILES OC(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1 Show InChI InChI=1S/C18H13Cl2N3O4S/c19-14-15-12(28-16(14)20)6-9(21-15)17(26)22-10-5-8-3-1-2-4-11(8)23(18(10)27)7-13(24)25/h1-4,6,10,21H,5,7H2,(H,22,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....				Bioorg Med Chem Lett 17: 394-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.037 BindingDB Entry DOI: 10.7270/Q2TM78DM
					More data for this Ligand-Target Pair

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