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Compile Data Set for Download or QSAR

Found 2 hits of ph data with Target = 'HIV-1 Reverse Transcriptase Mutant (L100I/K103N)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIV-1 Reverse Transcriptase Mutant (L100I/K103N)


(Human immunodeficiency virus type 1)
BDBM16189
PNG
(4-(3-Iodophenyl)-3-oxobutanenitrile | beta-ketonit...)
Show SMILES Ic1cccc(CC(=O)CC#N)c1
Show InChI InChI=1S/C10H8INO/c11-9-3-1-2-8(6-9)7-10(13)4-5-12/h1-3,6H,4,7H2
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.40E+3n/an/an/an/a7.537



Bar Ilan University



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 50: 2370-84 (2007)


Article DOI: 10.1021/jm0613121
BindingDB Entry DOI: 10.7270/Q2VM49J0
More data for this
Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (L100I/K103N)


(Human immunodeficiency virus type 1)
BDBM16196
PNG
(4-(3-Bromo-4-chlorophenyl)-1H-imidazole-5-carboxam...)
Show SMILES NC(=O)c1[nH]cnc1-c1ccc(Cl)c(Br)c1
Show InChI InChI=1S/C10H7BrClN3O/c11-6-3-5(1-2-7(6)12)8-9(10(13)16)15-4-14-8/h1-4H,(H2,13,16)(H,14,15)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.98E+4n/an/an/an/a7.537



Bar Ilan University



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 50: 2370-84 (2007)


Article DOI: 10.1021/jm0613121
BindingDB Entry DOI: 10.7270/Q2VM49J0
More data for this
Ligand-Target Pair