BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ph data with Target = 'HPr kinase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HPr kinase


(Bacillus subtilis)
BDBM50137122
PNG
((3-Benzyl-2-imino-2,3-dihydro-benzoimidazol-1-yl)-...)
Show SMILES N=c1n(CC(=O)N\N=C\c2ccc(\C=N\NC(=O)Cn3c4ccccc4n(Cc4ccccc4)c3=N)cc2)c2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C40H36N10O2/c41-39-47(25-31-11-3-1-4-12-31)33-15-7-9-17-35(33)49(39)27-37(51)45-43-23-29-19-21-30(22-20-29)24-44-46-38(52)28-50-36-18-10-8-16-34(36)48(40(50)42)26-32-13-5-2-6-14-32/h1-24,41-42H,25-28H2,(H,45,51)(H,46,52)/b41-39?,42-40?,43-23+,44-24+
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.70E+4n/an/an/an/a7.0n/a



ISIS-Universit£ Louis Pasteur

Curated by ChEMBL


Assay Description
Inhibition of bifunctional enzyme HPr kinase/phosphatase from Bacillus subtilis at pH 7.0 and hill coefficient of 1.4


J Med Chem 46: 5803-11 (2003)


Article DOI: 10.1021/jm030917j
BindingDB Entry DOI: 10.7270/Q2Z038WD
More data for this
Ligand-Target Pair
HPr kinase


(Bacillus subtilis)
BDBM50137122
PNG
((3-Benzyl-2-imino-2,3-dihydro-benzoimidazol-1-yl)-...)
Show SMILES N=c1n(CC(=O)N\N=C\c2ccc(\C=N\NC(=O)Cn3c4ccccc4n(Cc4ccccc4)c3=N)cc2)c2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C40H36N10O2/c41-39-47(25-31-11-3-1-4-12-31)33-15-7-9-17-35(33)49(39)27-37(51)45-43-23-29-19-21-30(22-20-29)24-44-46-38(52)28-50-36-18-10-8-16-34(36)48(40(50)42)26-32-13-5-2-6-14-32/h1-24,41-42H,25-28H2,(H,45,51)(H,46,52)/b41-39?,42-40?,43-23+,44-24+
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80E+4n/an/an/an/a8.0n/a



ISIS-Universit£ Louis Pasteur

Curated by ChEMBL


Assay Description
Inhibition of bifunctional enzyme HPr kinase/phosphatase from Bacillus subtilis at pH 8.0 and hill coefficient of 2.9


J Med Chem 46: 5803-11 (2003)


Article DOI: 10.1021/jm030917j
BindingDB Entry DOI: 10.7270/Q2Z038WD
More data for this
Ligand-Target Pair