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Compile Data Set for Download or QSAR

Found 403 hits of ph data with Target = 'Histone deacetylase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase


(Homo sapiens (human))
BDBM24622
PNG
(3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoy...)
Show SMILES CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO
Show InChI InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)
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Article
PubMed
17 -43.9n/an/an/an/an/a7.422



Celera Genomics



Assay Description
HDAC activity was measured using a continuous trypsin-coupled assay. For inhibitor characterization, measurements were done using 96-well assay plat...


Mol Cancer Ther 5: 1309-17 (2006)


Article DOI: 10.1158/1535-7163.MCT-05-0442
BindingDB Entry DOI: 10.7270/Q2DF6PJJ
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM24622
PNG
(3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoy...)
Show SMILES CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO
Show InChI InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)
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19 -43.6n/an/an/an/an/a7.422



Celera Genomics



Assay Description
HDAC activity was measured using a continuous trypsin-coupled assay. For inhibitor characterization, measurements were done using 96-well assay plat...


Mol Cancer Ther 5: 1309-17 (2006)


Article DOI: 10.1158/1535-7163.MCT-05-0442
BindingDB Entry DOI: 10.7270/Q2DF6PJJ
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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21 -43.4n/an/an/an/an/a7.422



University of Notre Dame



Assay Description
To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...


J Med Chem 51: 2898-906 (2008)


Article DOI: 10.1021/jm7015254
BindingDB Entry DOI: 10.7270/Q2NC5ZG2
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM22450
PNG
(N-hydroxy-N -(4-{(2R,4S,6R)-4-phenyl-6-[(pyridin-4...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@H]1O[C@@H](CSc2ccncc2)C[C@H](O1)c1ccccc1
Show InChI InChI=1S/C30H35N3O5S/c34-28(10-6-1-2-7-11-29(35)33-36)32-24-14-12-23(13-15-24)30-37-25(21-39-26-16-18-31-19-17-26)20-27(38-30)22-8-4-3-5-9-22/h3-5,8-9,12-19,25,27,30,36H,1-2,6-7,10-11,20-21H2,(H,32,34)(H,33,35)/t25-,27+,30+/m1/s1
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28 -42.7n/an/an/an/an/a7.422



University of Notre Dame



Assay Description
To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...


J Med Chem 51: 2898-906 (2008)


Article DOI: 10.1021/jm7015254
BindingDB Entry DOI: 10.7270/Q2NC5ZG2
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM22449
PNG
(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Show SMILES OCc1ccc(cc1)[C@@H]1C[C@H](CSc2nc(c(o2)-c2ccccc2)-c2ccccc2)O[C@@H](O1)c1ccc(NC(=O)CCCCCCC(=O)NO)cc1
Show InChI InChI=1S/C41H43N3O7S/c45-26-28-17-19-29(20-18-28)35-25-34(27-52-41-43-38(30-11-5-3-6-12-30)39(51-41)31-13-7-4-8-14-31)49-40(50-35)32-21-23-33(24-22-32)42-36(46)15-9-1-2-10-16-37(47)44-48/h3-8,11-14,17-24,34-35,40,45,48H,1-2,9-10,15-16,25-27H2,(H,42,46)(H,44,47)/t34-,35+,40+/m1/s1
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142 -38.7n/an/an/an/an/a7.422



University of Notre Dame



Assay Description
To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...


J Med Chem 51: 2898-906 (2008)


Article DOI: 10.1021/jm7015254
BindingDB Entry DOI: 10.7270/Q2NC5ZG2
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (Human))
BDBM36483
PNG
((S)-6-acetamido-2-(2-((S)-2-acetamido-4-methylpent...)
Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCNC(C)=O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
Show InChI InChI=1S/C28H39N5O7/c1-16(2)12-23(31-19(5)35)27(38)30-15-25(36)33-22(8-6-7-11-29-18(4)34)28(39)32-20-9-10-21-17(3)13-26(37)40-24(21)14-20/h9-10,13-14,16,22-23H,6-8,11-12,15H2,1-5H3,(H,29,34)(H,30,38)(H,31,35)(H,32,39)(H,33,36)/t22-,23-/m0/s1
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n/an/a 2.34E+3n/an/an/an/a7.40



Dana-Farber Cancer Institute



Assay Description
For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...


Nat Chem Biol 6: 238-243 (2010)


Article DOI: 10.1038/nchembio.313
BindingDB Entry DOI: 10.7270/Q2C53J66
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (Human))
BDBM36484
PNG
((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...)
Show SMILES CC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
Show InChI InChI=1S/C26H29N3O6/c1-17-14-24(31)35-23-15-20(11-12-21(17)23)28-25(32)22(10-6-7-13-27-18(2)30)29-26(33)34-16-19-8-4-3-5-9-19/h3-5,8-9,11-12,14-15,22H,6-7,10,13,16H2,1-2H3,(H,27,30)(H,28,32)(H,29,33)/t22-/m0/s1
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n/an/a 1.02E+3n/an/an/an/a7.40



Dana-Farber Cancer Institute



Assay Description
For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...


Nat Chem Biol 6: 238-243 (2010)


Article DOI: 10.1038/nchembio.313
BindingDB Entry DOI: 10.7270/Q2C53J66
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109949
PNG
(US8609678, 4-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H29N3O3/c30-25(28-32)15-9-1-2-10-20-27-26(31)21-16-18-24(19-17-21)29(22-11-5-3-6-12-22)23-13-7-4-8-14-23/h3-8,11-14,16-19,32H,1-2,9-10,15,20H2,(H,27,31)(H,28,30)
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n/an/a 18n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109950
PNG
(US8609678, 4-(dipyrimidin-2-ylamino)-N-(7-(hydroxy...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1ncccn1)c1ncccn1
Show InChI InChI=1S/C22H25N7O3/c30-19(28-32)7-3-1-2-4-12-23-20(31)17-8-10-18(11-9-17)29(21-24-13-5-14-25-21)22-26-15-6-16-27-22/h5-6,8-11,13-16,32H,1-4,7,12H2,(H,23,31)(H,28,30)
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n/an/a 174n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109951
PNG
(US8609678, 4-(bis(4-methoxyphenyl)amino)-N-(7-(hyd...)
Show SMILES COc1ccc(cc1)N(c1ccc(OC)cc1)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C28H33N3O5/c1-35-25-16-12-23(13-17-25)31(24-14-18-26(36-2)19-15-24)22-10-8-21(9-11-22)28(33)29-20-6-4-3-5-7-27(32)30-34/h8-19,34H,3-7,20H2,1-2H3,(H,29,33)(H,30,32)
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n/an/a 200n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109952
PNG
(US8609678, 4-((2,6-dichlorophenyl)(methyl)amino)-N...)
Show SMILES CN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1c(Cl)cccc1Cl
Show InChI InChI=1S/C21H25Cl2N3O3/c1-26(20-17(22)7-6-8-18(20)23)16-12-10-15(11-13-16)21(28)24-14-5-3-2-4-9-19(27)25-29/h6-8,10-13,29H,2-5,9,14H2,1H3,(H,24,28)(H,25,27)
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n/an/a 3n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109953
PNG
(US8609678, 4-(dipyrimidin-2-ylamino)-N-(8-(hydroxy...)
Show SMILES ONC(=O)CCCCCCCNC(=O)c1ccc(cc1)N(c1ncccn1)c1ncccn1
Show InChI InChI=1S/C23H27N7O3/c31-20(29-33)8-4-2-1-3-5-13-24-21(32)18-9-11-19(12-10-18)30(22-25-14-6-15-26-22)23-27-16-7-17-28-23/h6-7,9-12,14-17,33H,1-5,8,13H2,(H,24,32)(H,29,31)
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n/an/a 6n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109954
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(met...)
Show SMILES CN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C22H26F3N3O3/c1-28(19-9-6-5-8-18(19)22(23,24)25)17-13-11-16(12-14-17)21(30)26-15-7-3-2-4-10-20(29)27-31/h5-6,8-9,11-14,31H,2-4,7,10,15H2,1H3,(H,26,30)(H,27,29)
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n/an/a 3n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109955
PNG
(US8609678, 4-((2,6-diisopropylphenyl)(methyl)amino...)
Show SMILES CC(C)c1cccc(C(C)C)c1N(C)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C27H39N3O3/c1-19(2)23-11-10-12-24(20(3)4)26(23)30(5)22-16-14-21(15-17-22)27(32)28-18-9-7-6-8-13-25(31)29-33/h10-12,14-17,19-20,33H,6-9,13,18H2,1-5H3,(H,28,32)(H,29,31)
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n/an/a 45n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109956
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(met...)
Show SMILES CN(c1ccccc1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C19H25N5O3/c1-24(16-9-5-4-6-10-16)19-21-13-15(14-22-19)18(26)20-12-8-3-2-7-11-17(25)23-27/h4-6,9-10,13-14,27H,2-3,7-8,11-12H2,1H3,(H,20,26)(H,23,25)
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n/an/a 6n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109957
PNG
(US8609678, 4-(2,6-diisopropylphenylamino)-N-(7-(hy...)
Show SMILES CC(C)c1cccc(C(C)C)c1Nc1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C26H37N3O3/c1-18(2)22-10-9-11-23(19(3)4)25(22)28-21-15-13-20(14-16-21)26(31)27-17-8-6-5-7-12-24(30)29-32/h9-11,13-16,18-19,28,32H,5-8,12,17H2,1-4H3,(H,27,31)(H,29,30)
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n/an/a 20n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109958
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-((2-...)
Show SMILES CC(C)c1ccccc1N(C)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C22H31N5O3/c1-16(2)18-10-7-8-11-19(18)27(3)22-24-14-17(15-25-22)21(29)23-13-9-5-4-6-12-20(28)26-30/h7-8,10-11,14-16,30H,4-6,9,12-13H2,1-3H3,(H,23,29)(H,26,28)
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n/an/a 7n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109959
PNG
(US8609678, 4-(2,6-dimethylphenylamino)-N-(7-(hydro...)
Show SMILES Cc1cccc(C)c1Nc1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C22H29N3O3/c1-16-8-7-9-17(2)21(16)24-19-13-11-18(12-14-19)22(27)23-15-6-4-3-5-10-20(26)25-28/h7-9,11-14,24,28H,3-6,10,15H2,1-2H3,(H,23,27)(H,25,26)
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n/an/a 3n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109960
PNG
(US8609678, 4-(ethyl(2-(trifluoromethyl)phenyl)amin...)
Show SMILES CCN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C23H28F3N3O3/c1-2-29(20-10-7-6-9-19(20)23(24,25)26)18-14-12-17(13-15-18)22(31)27-16-8-4-3-5-11-21(30)28-32/h6-7,9-10,12-15,32H,2-5,8,11,16H2,1H3,(H,27,31)(H,28,30)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109961
PNG
(US8609678, 4-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Show SMILES CN(CCCCCCC(=O)NO)C(=O)c1ccc(cc1)N(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H31N3O3/c1-29(21-11-3-2-10-16-26(31)28-33)27(32)22-17-19-25(20-18-22)30(23-12-6-4-7-13-23)24-14-8-5-9-15-24/h4-9,12-15,17-20,33H,2-3,10-11,16,21H2,1H3,(H,28,31)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109962
PNG
(US8609678, 4-(dipyrimidin-2-ylamino)-N-(7-(hydroxy...)
Show SMILES CN(CCCCCCC(=O)NO)C(=O)c1ccc(cc1)N(c1ncccn1)c1ncccn1
Show InChI InChI=1S/C23H27N7O3/c1-29(17-5-3-2-4-8-20(31)28-33)21(32)18-9-11-19(12-10-18)30(22-24-13-6-14-25-22)23-26-15-7-16-27-23/h6-7,9-16,33H,2-5,8,17H2,1H3,(H,28,31)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109963
PNG
(US8609678, 4-((2,6-dichlorophenyl)(ethyl)amino)-N-...)
Show SMILES CCN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1c(Cl)cccc1Cl
Show InChI InChI=1S/C22H27Cl2N3O3/c1-2-27(21-18(23)8-7-9-19(21)24)17-13-11-16(12-14-17)22(29)25-15-6-4-3-5-10-20(28)26-30/h7-9,11-14,30H,2-6,10,15H2,1H3,(H,25,29)(H,26,28)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109964
PNG
(US8609678, 4-(2,6-dichlorophenylamino)-N-(7-(hydro...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(Nc2c(Cl)cccc2Cl)cc1
Show InChI InChI=1S/C20H23Cl2N3O3/c21-16-6-5-7-17(22)19(16)24-15-11-9-14(10-12-15)20(27)23-13-4-2-1-3-8-18(26)25-28/h5-7,9-12,24,28H,1-4,8,13H2,(H,23,27)(H,25,26)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109965
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(phe...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1ccccc1)c1ncccn1
Show InChI InChI=1S/C24H27N5O3/c30-22(28-32)11-6-1-2-7-16-25-23(31)19-12-14-21(15-13-19)29(20-9-4-3-5-10-20)24-26-17-8-18-27-24/h3-5,8-10,12-15,17-18,32H,1-2,6-7,11,16H2,(H,25,31)(H,28,30)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109966
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-((2-...)
Show SMILES CC(C)c1ccccc1N(C)c1ncc(cn1)C(=O)N(C)CCCCCCC(=O)NO
Show InChI InChI=1S/C23H33N5O3/c1-17(2)19-11-8-9-12-20(19)28(4)23-24-15-18(16-25-23)22(30)27(3)14-10-6-5-7-13-21(29)26-31/h8-9,11-12,15-17,31H,5-7,10,13-14H2,1-4H3,(H,26,29)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109967
PNG
(US8609678, 4-((2-chloro-6-methylphenyl)(methyl)ami...)
Show SMILES CN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1c(C)cccc1Cl
Show InChI InChI=1S/C22H28ClN3O3/c1-16-8-7-9-19(23)21(16)26(2)18-13-11-17(12-14-18)22(28)24-15-6-4-3-5-10-20(27)25-29/h7-9,11-14,29H,3-6,10,15H2,1-2H3,(H,24,28)(H,25,27)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109968
PNG
(US8609678, 4-((2,6-difluorophenyl)(methyl)amino)-N...)
Show SMILES CN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1c(F)cccc1F
Show InChI InChI=1S/C21H25F2N3O3/c1-26(20-17(22)7-6-8-18(20)23)16-12-10-15(11-13-16)21(28)24-14-5-3-2-4-9-19(27)25-29/h6-8,10-13,29H,2-5,9,14H2,1H3,(H,24,28)(H,25,27)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109969
PNG
(US8609678, 4-(ethyl(2-(trifluoromethyl)phenyl)amin...)
Show SMILES CCN(c1ccc(cc1)C(=O)N(C)CCCCCCC(=O)NO)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O3/c1-3-30(21-11-8-7-10-20(21)24(25,26)27)19-15-13-18(14-16-19)23(32)29(2)17-9-5-4-6-12-22(31)28-33/h7-8,10-11,13-16,33H,3-6,9,12,17H2,1-2H3,(H,28,31)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109970
PNG
(US8609678, 4-(2,6-difluorophenylamino)-N-(7-(hydro...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(Nc2c(F)cccc2F)cc1
Show InChI InChI=1S/C20H23F2N3O3/c21-16-6-5-7-17(22)19(16)24-15-11-9-14(10-12-15)20(27)23-13-4-2-1-3-8-18(26)25-28/h5-7,9-12,24,28H,1-4,8,13H2,(H,23,27)(H,25,26)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109971
PNG
(US8609678, 4-(bis(3-chlorophenyl)amino)-N-(7-(hydr...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1cccc(Cl)c1)c1cccc(Cl)c1
Show InChI InChI=1S/C26H27Cl2N3O3/c27-20-7-5-9-23(17-20)31(24-10-6-8-21(28)18-24)22-14-12-19(13-15-22)26(33)29-16-4-2-1-3-11-25(32)30-34/h5-10,12-15,17-18,34H,1-4,11,16H2,(H,29,33)(H,30,32)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109968
PNG
(US8609678, 4-((2,6-difluorophenyl)(methyl)amino)-N...)
Show SMILES CN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1c(F)cccc1F
Show InChI InChI=1S/C21H25F2N3O3/c1-26(20-17(22)7-6-8-18(20)23)16-12-10-15(11-13-16)21(28)24-14-5-3-2-4-9-19(27)25-29/h6-8,10-13,29H,2-5,9,14H2,1H3,(H,24,28)(H,25,27)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109973
PNG
(US8609678, 2-(2,6-dimethylphenylamino)-N-(7-(hydro...)
Show SMILES Cc1cccc(C)c1Nc1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C20H27N5O3/c1-14-8-7-9-15(2)18(14)24-20-22-12-16(13-23-20)19(27)21-11-6-4-3-5-10-17(26)25-28/h7-9,12-13,28H,3-6,10-11H2,1-2H3,(H,21,27)(H,25,26)(H,22,23,24)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM50439674
PNG
(RICOLINOSTAT | US8609678, 2-(diphenylamino)-N-(7-(...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H27N5O3/c30-22(28-32)15-9-1-2-10-16-25-23(31)19-17-26-24(27-18-19)29(20-11-5-3-6-12-20)21-13-7-4-8-14-21/h3-8,11-14,17-18,32H,1-2,9-10,15-16H2,(H,25,31)(H,28,30)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109974
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(met...)
Show SMILES CN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1cnccn1
Show InChI InChI=1S/C19H25N5O3/c1-24(17-14-20-12-13-21-17)16-9-7-15(8-10-16)19(26)22-11-5-3-2-4-6-18(25)23-27/h7-10,12-14,27H,2-6,11H2,1H3,(H,22,26)(H,23,25)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109975
PNG
(US8609678, 4-(2,6-dimethylphenylamino)-N-(7-(hydro...)
Show SMILES CN(CCCCCCC(=O)NO)C(=O)c1ccc(Nc2c(C)cccc2C)cc1
Show InChI InChI=1S/C23H31N3O3/c1-17-9-8-10-18(2)22(17)24-20-14-12-19(13-15-20)23(28)26(3)16-7-5-4-6-11-21(27)25-29/h8-10,12-15,24,29H,4-7,11,16H2,1-3H3,(H,25,27)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109976
PNG
(US8609678, 4-(ethyl(pyrazin-2-yl)amino)-N-(7-(hydr...)
Show SMILES CCN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1cnccn1
Show InChI InChI=1S/C20H27N5O3/c1-2-25(18-15-21-13-14-22-18)17-10-8-16(9-11-17)20(27)23-12-6-4-3-5-7-19(26)24-28/h8-11,13-15,28H,2-7,12H2,1H3,(H,23,27)(H,24,26)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109977
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(1-m...)
Show SMILES Cn1c(Nc2ccc(cc2)C(=O)NCCCCCCC(=O)NO)nc2ccccc12
Show InChI InChI=1S/C22H27N5O3/c1-27-19-9-6-5-8-18(19)25-22(27)24-17-13-11-16(12-14-17)21(29)23-15-7-3-2-4-10-20(28)26-30/h5-6,8-9,11-14,30H,2-4,7,10,15H2,1H3,(H,23,29)(H,24,25)(H,26,28)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109978
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(phe...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1ccccc1)c1cncnc1
Show InChI InChI=1S/C24H27N5O3/c30-23(28-32)10-6-1-2-7-15-27-24(31)19-11-13-21(14-12-19)29(20-8-4-3-5-9-20)22-16-25-18-26-17-22/h3-5,8-9,11-14,16-18,32H,1-2,6-7,10,15H2,(H,27,31)(H,28,30)
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n/an/a 12n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109979
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(N-p...)
Show SMILES CC(=O)N(c1ccccc1)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C22H27N3O4/c1-17(26)25(19-9-5-4-6-10-19)20-14-12-18(13-15-20)22(28)23-16-8-3-2-7-11-21(27)24-29/h4-6,9-10,12-15,29H,2-3,7-8,11,16H2,1H3,(H,23,28)(H,24,27)
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n/an/a 3n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109980
PNG
(US8609678, 4-(benzo[d]oxazol-2-ylamino)-N-(7-(hydr...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(Nc2nc3ccccc3o2)cc1
Show InChI InChI=1S/C21H24N4O4/c26-19(25-28)9-3-1-2-6-14-22-20(27)15-10-12-16(13-11-15)23-21-24-17-7-4-5-8-18(17)29-21/h4-5,7-8,10-13,28H,1-3,6,9,14H2,(H,22,27)(H,23,24)(H,25,26)
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n/an/a 3n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109981
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(phe...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1ccccc1)c1cnccn1
Show InChI InChI=1S/C24H27N5O3/c30-23(28-32)10-6-1-2-7-15-27-24(31)19-11-13-21(14-12-19)29(20-8-4-3-5-9-20)22-18-25-16-17-26-22/h3-5,8-9,11-14,16-18,32H,1-2,6-7,10,15H2,(H,27,31)(H,28,30)
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n/an/a 14n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109982
PNG
(US8609678, 2-(2,6-dimethylphenylamino)-N-(7-(hydro...)
Show SMILES CN(CCCCCCC(=O)NO)C(=O)c1cnc(Nc2c(C)cccc2C)nc1
Show InChI InChI=1S/C21H29N5O3/c1-15-9-8-10-16(2)19(15)24-21-22-13-17(14-23-21)20(28)26(3)12-7-5-4-6-11-18(27)25-29/h8-10,13-14,29H,4-7,11-12H2,1-3H3,(H,25,27)(H,22,23,24)
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n/an/a 33n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109983
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(phe...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1ccccc1)c1ccccn1
Show InChI InChI=1S/C25H28N4O3/c30-24(28-32)13-6-1-2-8-19-27-25(31)20-14-16-22(17-15-20)29(21-10-4-3-5-11-21)23-12-7-9-18-26-23/h3-5,7,9-12,14-18,32H,1-2,6,8,13,19H2,(H,27,31)(H,28,30)
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n/an/a 14n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109984
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(N-p...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1ccccc1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H29N3O5S/c30-25(28-32)15-9-1-2-10-20-27-26(31)21-16-18-23(19-17-21)29(22-11-5-3-6-12-22)35(33,34)24-13-7-4-8-14-24/h3-8,11-14,16-19,32H,1-2,9-10,15,20H2,(H,27,31)(H,28,30)
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n/an/a 15n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109985
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(phe...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(c1ccccc1)c1cccnc1
Show InChI InChI=1S/C25H28N4O3/c30-24(28-32)12-6-1-2-7-18-27-25(31)20-13-15-22(16-14-20)29(21-9-4-3-5-10-21)23-11-8-17-26-19-23/h3-5,8-11,13-17,19,32H,1-2,6-7,12,18H2,(H,27,31)(H,28,30)
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n/an/a 21n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109986
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-((3-...)
Show SMILES Cc1cccnc1N(c1ccccc1)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C26H30N4O3/c1-20-10-9-19-27-25(20)30(22-11-5-4-6-12-22)23-16-14-21(15-17-23)26(32)28-18-8-3-2-7-13-24(31)29-33/h4-6,9-12,14-17,19,33H,2-3,7-8,13,18H2,1H3,(H,28,32)(H,29,31)
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n/an/a 20n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109987
PNG
(US8609678, 4-(benzo[d]oxazol-2-yl(methyl)amino)-N-...)
Show SMILES CN(CCCCCCC(=O)NO)C(=O)c1ccc(cc1)N(C)c1nc2ccccc2o1
Show InChI InChI=1S/C23H28N4O4/c1-26(16-8-4-3-5-11-21(28)25-30)22(29)17-12-14-18(15-13-17)27(2)23-24-19-9-6-7-10-20(19)31-23/h6-7,9-10,12-15,30H,3-5,8,11,16H2,1-2H3,(H,25,28)
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n/an/a 107n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109988
PNG
(US8609678, 4-(benzo[d]oxazol-2-yl(methyl)amino)-N-...)
Show SMILES CN(c1nc2ccccc2o1)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C22H26N4O4/c1-26(22-24-18-8-5-6-9-19(18)30-22)17-13-11-16(12-14-17)21(28)23-15-7-3-2-4-10-20(27)25-29/h5-6,8-9,11-14,29H,2-4,7,10,15H2,1H3,(H,23,28)(H,25,27)
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n/an/a 11n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109989
PNG
(US8609678, 4-((2-cyanophenyl)(methyl)amino)-N-(7-(...)
Show SMILES CN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1ccccc1C#N
Show InChI InChI=1S/C22H26N4O3/c1-26(20-9-6-5-8-18(20)16-23)19-13-11-17(12-14-19)22(28)24-15-7-3-2-4-10-21(27)25-29/h5-6,8-9,11-14,29H,2-4,7,10,15H2,1H3,(H,24,28)(H,25,27)
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n/an/a 4n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM109990
PNG
(US8609678, 4-(benzo[d]thiazol-2-ylamino)-N-(7-(hyd...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(Nc2nc3ccccc3s2)cc1
Show InChI InChI=1S/C21H24N4O3S/c26-19(25-28)9-3-1-2-6-14-22-20(27)15-10-12-16(13-11-15)23-21-24-17-7-4-5-8-18(17)29-21/h4-5,7-8,10-13,28H,1-3,6,9,14H2,(H,22,27)(H,23,24)(H,25,26)
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n/an/a 12n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
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