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Found 2 of ph data with Target = 'Histone-lysine N-methyltransferase EZH2 [Y641H]'
TargetHistone-lysine N-methyltransferase EZH2 [Y641H](Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM190225(US9175331, 75)
Affinity DataIC50:  7.56E+3nMpH: 7.6Assay Description:Compound 75 was serially diluted 3 fold in DMSO for 10 points and 1 μL , was plated in a 384 well microtiter plate. Positive control (100% inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641H](Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  263nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair