BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 184 hits of ph data with Target = 'Hypoxia-inducible factor prolyl hydroxylase 1'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240906
PNG
(US9409892, 1)
Show SMILES OC(=O)CCNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C19H16N2O5/c22-16(23)8-9-20-19(25)17-18(24)15-7-6-14(10-12(15)11-21-17)26-13-4-2-1-3-5-13/h1-7,10-11,24H,8-9H2,(H,20,25)(H,22,23)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 920n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240907
PNG
(US9409892, 2)
Show SMILES CC(C)(CNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C21H20N2O5/c1-21(2,20(26)27)12-23-19(25)17-18(24)16-9-8-15(10-13(16)11-22-17)28-14-6-4-3-5-7-14/h3-11,24H,12H2,1-2H3,(H,23,25)(H,26,27)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240908
PNG
(US9409892, 3)
Show SMILES O[C@@H](CNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C19H16N2O6/c22-15(19(25)26)10-21-18(24)16-17(23)14-7-6-13(8-11(14)9-20-16)27-12-4-2-1-3-5-12/h1-9,15,22-23H,10H2,(H,21,24)(H,25,26)/t15-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.08E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240909
PNG
(US9409892, 4)
Show SMILES OC(=O)CCCNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C20H18N2O5/c23-17(24)7-4-10-21-20(26)18-19(25)16-9-8-15(11-13(16)12-22-18)27-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,25H,4,7,10H2,(H,21,26)(H,23,24)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.17E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240910
PNG
(US9409892, 5)
Show SMILES OC(=O)CCCCNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H20N2O5/c24-18(25)8-4-5-11-22-21(27)19-20(26)17-10-9-16(12-14(17)13-23-19)28-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,26H,4-5,8,11H2,(H,22,27)(H,24,25)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.75E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240911
PNG
(US9409892, 6)
Show SMILES CC(C)(CC(O)=O)NC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H20N2O5/c1-21(2,11-17(24)25)23-20(27)18-19(26)16-9-8-15(10-13(16)12-22-18)28-14-6-4-3-5-7-14/h3-10,12,26H,11H2,1-2H3,(H,23,27)(H,24,25)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.19E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240912
PNG
(US9409892, 7)
Show SMILES O[C@@H](CCNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C20H18N2O6/c23-16(20(26)27)8-9-21-19(25)17-18(24)15-7-6-14(10-12(15)11-22-17)28-13-4-2-1-3-5-13/h1-7,10-11,16,23-24H,8-9H2,(H,21,25)(H,26,27)/t16-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.02E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240913
PNG
(US9409892, 8)
Show SMILES CC(C)(CCNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H22N2O5/c1-22(2,21(27)28)10-11-23-20(26)18-19(25)17-9-8-16(12-14(17)13-24-18)29-15-6-4-3-5-7-15/h3-9,12-13,25H,10-11H2,1-2H3,(H,23,26)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.16E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240914
PNG
(US9409892, 9)
Show SMILES N[C@@H](CNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C19H17N3O5/c20-15(19(25)26)10-22-18(24)16-17(23)14-7-6-13(8-11(14)9-21-16)27-12-4-2-1-3-5-12/h1-9,15,23H,10,20H2,(H,22,24)(H,25,26)/t15-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.39E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240915
PNG
(US9409892, 10)
Show SMILES OC(=O)CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C20H15N3O5/c21-11-16-15-10-13(28-12-4-2-1-3-5-12)6-7-14(15)19(26)18(23-16)20(27)22-9-8-17(24)25/h1-7,10,26H,8-9H2,(H,22,27)(H,24,25)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 240n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240916
PNG
(US9409892, 11)
Show SMILES CC(CC(O)=O)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H17N3O5/c1-12(9-18(25)26)23-21(28)19-20(27)15-8-7-14(10-16(15)17(11-22)24-19)29-13-5-3-2-4-6-13/h2-8,10,12,27H,9H2,1H3,(H,23,28)(H,25,26)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.37E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240917
PNG
(US9409892, 12)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CC1
Show InChI InChI=1S/C22H17N3O5/c23-11-17-16-10-14(30-13-4-2-1-3-5-13)6-7-15(16)19(26)18(25-17)20(27)24-12-22(8-9-22)21(28)29/h1-7,10,26H,8-9,12H2,(H,24,27)(H,28,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 170n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240918
PNG
(US9409892, 13)
Show SMILES OC(=O)C1(CNC(=O)c2ncc3cc(Oc4ccccc4)ccc3c2O)CCC1
Show InChI InChI=1S/C22H20N2O5/c25-19-17-8-7-16(29-15-5-2-1-3-6-15)11-14(17)12-23-18(19)20(26)24-13-22(21(27)28)9-4-10-22/h1-3,5-8,11-12,25H,4,9-10,13H2,(H,24,26)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.51E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240919
PNG
(US9409892, 14)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCC1
Show InChI InChI=1S/C23H19N3O5/c24-12-18-17-11-15(31-14-5-2-1-3-6-14)7-8-16(17)20(27)19(26-18)21(28)25-13-23(22(29)30)9-4-10-23/h1-3,5-8,11,27H,4,9-10,13H2,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 310n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240920
PNG
(US9409892, 15)
Show SMILES OC(=O)C1(CNC(=O)c2ncc3cc(Oc4ccccc4)ccc3c2O)CCOCC1
Show InChI InChI=1S/C23H22N2O6/c26-20-18-7-6-17(31-16-4-2-1-3-5-16)12-15(18)13-24-19(20)21(27)25-14-23(22(28)29)8-10-30-11-9-23/h1-7,12-13,26H,8-11,14H2,(H,25,27)(H,28,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.71E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240921
PNG
(US9409892, 16)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCOCC1
Show InChI InChI=1S/C24H21N3O6/c25-13-19-18-12-16(33-15-4-2-1-3-5-15)6-7-17(18)21(28)20(27-19)22(29)26-14-24(23(30)31)8-10-32-11-9-24/h1-7,12,28H,8-11,14H2,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.89E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240922
PNG
(US9409892, 17)
Show SMILES CCCC(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C23H21N3O5/c1-2-6-14(23(29)30)13-25-22(28)20-21(27)17-10-9-16(11-18(17)19(12-24)26-20)31-15-7-4-3-5-8-15/h3-5,7-11,14,27H,2,6,13H2,1H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.39E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240923
PNG
(US9409892, 18)
Show SMILES CCCC(CCC)(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C26H27N3O5/c1-3-12-26(13-4-2,25(32)33)16-28-24(31)22-23(30)19-11-10-18(14-20(19)21(15-27)29-22)34-17-8-6-5-7-9-17/h5-11,14,30H,3-4,12-13,16H2,1-2H3,(H,28,31)(H,32,33)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.43E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240924
PNG
(US9409892, 19)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCCC1
Show InChI InChI=1S/C24H21N3O5/c25-13-19-18-12-16(32-15-6-2-1-3-7-15)8-9-17(18)21(28)20(27-19)22(29)26-14-24(23(30)31)10-4-5-11-24/h1-3,6-9,12,28H,4-5,10-11,14H2,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.73E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240925
PNG
(US9409892, 20)
Show SMILES COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NCC(C)(C)C(O)=O)cc1
Show InChI InChI=1S/C23H21N3O6/c1-23(2,22(29)30)12-25-21(28)19-20(27)16-9-8-15(10-17(16)18(11-24)26-19)32-14-6-4-13(31-3)5-7-14/h4-10,27H,12H2,1-3H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 350n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240926
PNG
(US9409892, 21)
Show SMILES COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NC(C)(C)CC(O)=O)cc1
Show InChI InChI=1S/C23H21N3O6/c1-23(2,11-19(27)28)26-22(30)20-21(29)16-9-8-15(10-17(16)18(12-24)25-20)32-14-6-4-13(31-3)5-7-14/h4-10,29H,11H2,1-3H3,(H,26,30)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 240n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240927
PNG
(US9409892, 22)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3c(F)cccc3F)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H17F2N3O5/c1-22(2,21(30)31)10-26-20(29)17-18(28)12-7-6-11(8-13(12)16(9-25)27-17)32-19-14(23)4-3-5-15(19)24/h3-8,28H,10H2,1-2H3,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 930n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240928
PNG
(US9409892, 23)
Show SMILES CC(C)(CNC(=O)c1ncc2cc(Oc3ccc(Cl)c(F)c3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C21H18ClFN2O5/c1-21(2,20(28)29)10-25-19(27)17-18(26)14-5-3-12(7-11(14)9-24-17)30-13-4-6-15(22)16(23)8-13/h3-9,26H,10H2,1-2H3,(H,25,27)(H,28,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.77E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240929
PNG
(US9409892, 24)
Show SMILES OC(=O)CCNC(=O)c1ncc2cc(Oc3cccnc3)ccc2c1O
Show InChI InChI=1S/C18H15N3O5/c22-15(23)5-7-20-18(25)16-17(24)14-4-3-12(8-11(14)9-21-16)26-13-2-1-6-19-10-13/h1-4,6,8-10,24H,5,7H2,(H,20,25)(H,22,23)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.31E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240930
PNG
(US9409892, 25)
Show SMILES OC(=O)CCNC(=O)c1ncc2cc(Oc3ccccn3)ccc2c1O
Show InChI InChI=1S/C18H15N3O5/c22-15(23)6-8-20-18(25)16-17(24)13-5-4-12(9-11(13)10-21-16)26-14-3-1-2-7-19-14/h1-5,7,9-10,24H,6,8H2,(H,20,25)(H,22,23)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.57E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240931
PNG
(US9409892, 26)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4c(F)cccc4F)ccc3c2O)CCC1
Show InChI InChI=1S/C23H17F2N3O5/c24-15-3-1-4-16(25)20(15)33-12-5-6-13-14(9-12)17(10-26)28-18(19(13)29)21(30)27-11-23(22(31)32)7-2-8-23/h1,3-6,9,29H,2,7-8,11H2,(H,27,30)(H,31,32)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 700n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240932
PNG
(US9409892, 27)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3cccnc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C21H18N4O5/c1-21(2,20(28)29)11-24-19(27)17-18(26)14-6-5-12(8-15(14)16(9-22)25-17)30-13-4-3-7-23-10-13/h3-8,10,26H,11H2,1-2H3,(H,24,27)(H,28,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.27E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240933
PNG
(US9409892, 28)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4cccnc4)ccc3c2O)CCC1
Show InChI InChI=1S/C22H18N4O5/c23-10-17-16-9-13(31-14-3-1-8-24-11-14)4-5-15(16)19(27)18(26-17)20(28)25-12-22(21(29)30)6-2-7-22/h1,3-5,8-9,11,27H,2,6-7,12H2,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.30E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240934
PNG
(US9409892, 29)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCS(=O)(=O)CC1
Show InChI InChI=1S/C24H21N3O7S/c25-13-19-18-12-16(34-15-4-2-1-3-5-15)6-7-17(18)21(28)20(27-19)22(29)26-14-24(23(30)31)8-10-35(32,33)11-9-24/h1-7,12,28H,8-11,14H2,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.76E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240935
PNG
(US9409892, 30)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCS(=O)CC1
Show InChI InChI=1S/C24H21N3O6S/c25-13-19-18-12-16(33-15-4-2-1-3-5-15)6-7-17(18)21(28)20(27-19)22(29)26-14-24(23(30)31)8-10-34(32)11-9-24/h1-7,12,28H,8-11,14H2,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.51E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240936
PNG
(US9409892, 31)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3cc(F)ccc3Cl)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H17ClFN3O5/c1-22(2,21(30)31)10-26-20(29)18-19(28)13-5-4-12(8-14(13)16(9-25)27-18)32-17-7-11(24)3-6-15(17)23/h3-8,28H,10H2,1-2H3,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 530n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240937
PNG
(US9409892, 32)
Show SMILES OC(=O)[C@@H]1CCCCC1NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C24H21N3O5/c25-13-20-18-12-15(32-14-6-2-1-3-7-14)10-11-16(18)22(28)21(26-20)23(29)27-19-9-5-4-8-17(19)24(30)31/h1-3,6-7,10-12,17,19,28H,4-5,8-9H2,(H,27,29)(H,30,31)/t17-,19?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.80E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240938
PNG
(US9409892, 33)
Show SMILES OC(=O)[C@@H]1CCCC1NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C23H19N3O5/c24-12-19-17-11-14(31-13-5-2-1-3-6-13)9-10-15(17)21(27)20(25-19)22(28)26-18-8-4-7-16(18)23(29)30/h1-3,5-6,9-11,16,18,27H,4,7-8H2,(H,26,28)(H,29,30)/t16-,18?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.69E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240939
PNG
(US9409892, 34)
Show SMILES OC(=O)CC(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)c1ccc(Cl)cc1
Show InChI InChI=1S/C27H20ClN3O5/c28-18-8-6-16(7-9-18)17(12-24(32)33)15-30-27(35)25-26(34)21-11-10-20(13-22(21)23(14-29)31-25)36-19-4-2-1-3-5-19/h1-11,13,17,34H,12,15H2,(H,30,35)(H,32,33)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.55E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240940
PNG
(US9409892, 35)
Show SMILES O[C@H](CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)CC(O)=O
Show InChI InChI=1S/C21H17N3O6/c22-10-17-16-9-14(30-13-4-2-1-3-5-13)6-7-15(16)20(28)19(24-17)21(29)23-11-12(25)8-18(26)27/h1-7,9,12,25,28H,8,11H2,(H,23,29)(H,26,27)/t12-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 230n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240941
PNG
(US9409892, 36)
Show SMILES OC(=O)CC1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCCCC1
Show InChI InChI=1S/C26H25N3O5/c27-15-21-20-13-18(34-17-7-3-1-4-8-17)9-10-19(20)24(32)23(29-21)25(33)28-16-26(14-22(30)31)11-5-2-6-12-26/h1,3-4,7-10,13,32H,2,5-6,11-12,14,16H2,(H,28,33)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.93E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240942
PNG
(US9409892, 37)
Show SMILES OC[C@@H](CC(O)=O)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H17N3O6/c22-10-17-16-9-14(30-13-4-2-1-3-5-13)6-7-15(16)20(28)19(24-17)21(29)23-12(11-25)8-18(26)27/h1-7,9,12,25,28H,8,11H2,(H,23,29)(H,26,27)/t12-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.67E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240943
PNG
(US9409892, 38)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3Cl)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H18ClN3O5/c1-22(2,21(29)30)11-25-20(28)18-19(27)13-8-7-12(9-14(13)16(10-24)26-18)31-17-6-4-3-5-15(17)23/h3-9,27H,11H2,1-2H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 240n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240944
PNG
(US9409892, 39)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3cccc(Cl)c3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H18ClN3O5/c1-22(2,21(29)30)11-25-20(28)18-19(27)15-7-6-14(9-16(15)17(10-24)26-18)31-13-5-3-4-12(23)8-13/h3-9,27H,11H2,1-2H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 180n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240945
PNG
(US9409892, 40)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccc(Cl)cc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H18ClN3O5/c1-22(2,21(29)30)11-25-20(28)18-19(27)15-8-7-14(9-16(15)17(10-24)26-18)31-13-5-3-12(23)4-6-13/h3-9,27H,11H2,1-2H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240946
PNG
(US9409892, 41)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3F)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H18FN3O5/c1-22(2,21(29)30)11-25-20(28)18-19(27)13-8-7-12(9-14(13)16(10-24)26-18)31-17-6-4-3-5-15(17)23/h3-9,27H,11H2,1-2H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240947
PNG
(US9409892, 42)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3cccc(F)c3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H18FN3O5/c1-22(2,21(29)30)11-25-20(28)18-19(27)15-7-6-14(9-16(15)17(10-24)26-18)31-13-5-3-4-12(23)8-13/h3-9,27H,11H2,1-2H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 360n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240948
PNG
(US9409892, 43)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3cccc4ccccc34)ccc2c1O)C(O)=O
Show InChI InChI=1S/C26H21N3O5/c1-26(2,25(32)33)14-28-24(31)22-23(30)18-11-10-16(12-19(18)20(13-27)29-22)34-21-9-5-7-15-6-3-4-8-17(15)21/h3-12,30H,14H2,1-2H3,(H,28,31)(H,32,33)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 220n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240949
PNG
(US9409892, 44)
Show SMILES Cc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NCC(C)(C)C(O)=O)cc1
Show InChI InChI=1S/C23H21N3O5/c1-13-4-6-14(7-5-13)31-15-8-9-16-17(10-15)18(11-24)26-19(20(16)27)21(28)25-12-23(2,3)22(29)30/h4-10,27H,12H2,1-3H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 280n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240950
PNG
(US9409892, 45)
Show SMILES N[C@@H](CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C21H18N4O5/c22-11-17-15-10-13(30-12-4-2-1-3-5-12)6-7-14(15)19(26)18(25-17)20(27)24-9-8-16(23)21(28)29/h1-7,10,16,26H,8-9,23H2,(H,24,27)(H,28,29)/t16-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.41E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240951
PNG
(US9409892, 46)
Show SMILES CC(C)(CCC(O)=O)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C23H21N3O5/c1-23(2,11-10-19(27)28)26-22(30)20-21(29)16-9-8-15(12-17(16)18(13-24)25-20)31-14-6-4-3-5-7-14/h3-9,12,29H,10-11H2,1-2H3,(H,26,30)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 940n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240952
PNG
(US9409892, 47)
Show SMILES OC(=O)C[C@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)c1ccccc1
Show InChI InChI=1S/C26H19N3O5/c27-15-22-20-13-18(34-17-9-5-2-6-10-17)11-12-19(20)25(32)24(28-22)26(33)29-21(14-23(30)31)16-7-3-1-4-8-16/h1-13,21,32H,14H2,(H,29,33)(H,30,31)/t21-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.28E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240953
PNG
(US9409892, 48)
Show SMILES OC(=O)C[C@@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)c1ccccc1
Show InChI InChI=1S/C26H19N3O5/c27-15-22-20-13-18(34-17-9-5-2-6-10-17)11-12-19(20)25(32)24(28-22)26(33)29-21(14-23(30)31)16-7-3-1-4-8-16/h1-13,21,32H,14H2,(H,29,33)(H,30,31)/t21-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.42E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240954
PNG
(US9409892, 49)
Show SMILES OC(=O)[C@H](CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)Cc1ccccc1
Show InChI InChI=1S/C27H21N3O5/c28-15-23-22-14-20(35-19-9-5-2-6-10-19)11-12-21(22)25(31)24(30-23)26(32)29-16-18(27(33)34)13-17-7-3-1-4-8-17/h1-12,14,18,31H,13,16H2,(H,29,32)(H,33,34)/t18-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.66E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM240955
PNG
(US9409892, 50)
Show SMILES N[C@H](CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C21H18N4O5/c22-11-17-15-10-13(30-12-4-2-1-3-5-12)6-7-14(15)19(26)18(25-17)20(27)24-9-8-16(23)21(28)29/h1-7,10,16,26H,8-9,23H2,(H,24,27)(H,28,29)/t16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.19E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 184 total )  |  Next  |  Last  >>
Jump to: