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Compile Data Set for Download or QSAR

Found 193 hits of ph data with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273013
PNG
((R)-N-(2-chlorobenzyl)-2-[7-oxo-6-(propan-2-yl)-5-...)
Show SMILES CC(C)n1c(nc2sc(nc2c1=O)[C@H]1CCCN1C(=O)NCc1ccccc1Cl)C(F)(F)F
Show InChI InChI=1S/C21H21ClF3N5O2S/c1-11(2)30-18(31)15-17(28-19(30)21(23,24)25)33-16(27-15)14-8-5-9-29(14)20(32)26-10-12-6-3-4-7-13(12)22/h3-4,6-7,11,14H,5,8-10H2,1-2H3,(H,26,32)/t14-/m1/s1
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n/an/a 6.20E+3n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273011
PNG
((R)-2-{6-methyl-5-[(morpholin-4-yl)methyl]-7-oxo-6...)
Show SMILES Cn1c(CN2CCOCC2)nc2sc(nc2c1=O)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C23H27N5O4S/c1-26-18(14-27-10-12-31-13-11-27)24-21-19(22(26)29)25-20(33-21)17-8-5-9-28(17)23(30)32-15-16-6-3-2-4-7-16/h2-4,6-7,17H,5,8-15H2,1H3/t17-/m1/s1
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n/an/a 610n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273012
PNG
((R)-N-benzyl-2-(5-ethyl-6-methyl-7-oxo-6,7-dihydro...)
Show SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)NCc1ccccc1
Show InChI InChI=1S/C20H23N5O2S/c1-3-15-22-18-16(19(26)24(15)2)23-17(28-18)14-10-7-11-25(14)20(27)21-12-13-8-5-4-6-9-13/h4-6,8-9,14H,3,7,10-12H2,1-2H3,(H,21,27)/t14-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273014
PNG
((R)-2-(5-ethyl-6-methyl-7-oxo-6,7-dihydro[1,3]thia...)
Show SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)NC1(CC1)c1ccccc1
Show InChI InChI=1S/C22H25N5O2S/c1-3-16-23-19-17(20(28)26(16)2)24-18(30-19)15-10-7-13-27(15)21(29)25-22(11-12-22)14-8-5-4-6-9-14/h4-6,8-9,15H,3,7,10-13H2,1-2H3,(H,25,29)/t15-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273015
PNG
((R)-5-ethyl-2-{1-[((R)-indan-1-yl)aminocarbonyl]py...)
Show SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)N[C@@H]1CCc2ccccc12
Show InChI InChI=1S/C22H25N5O2S/c1-3-17-24-20-18(21(28)26(17)2)25-19(30-20)16-9-6-12-27(16)22(29)23-15-11-10-13-7-4-5-8-14(13)15/h4-5,7-8,15-16H,3,6,9-12H2,1-2H3,(H,23,29)/t15-,16-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273016
PNG
((R)-2-{1-[2-(3,4-dihydro-2H-quinolin-1-yl)acetyl]p...)
Show SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)CN1CCCc2ccccc12
Show InChI InChI=1S/C23H27N5O2S/c1-3-18-24-22-20(23(30)26(18)2)25-21(31-22)17-11-7-13-28(17)19(29)14-27-12-6-9-15-8-4-5-10-16(15)27/h4-5,8,10,17H,3,6-7,9,11-14H2,1-2H3/t17-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273017
PNG
((R)-2-(5-ethyl-6-methyl-7-oxo-6,7-dihydro[1,3]thia...)
Show SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)NC(C)(C)c1ccccc1
Show InChI InChI=1S/C22H27N5O2S/c1-5-16-23-19-17(20(28)26(16)4)24-18(30-19)15-12-9-13-27(15)21(29)25-22(2,3)14-10-7-6-8-11-14/h6-8,10-11,15H,5,9,12-13H2,1-4H3,(H,25,29)/t15-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273018
PNG
((R)-2-(5-ethyl-6-methyl-7-oxo-6,7-dihydro[1,3]thia...)
Show SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)N[C@H](C)c1ccccc1
Show InChI InChI=1S/C21H25N5O2S/c1-4-16-23-19-17(20(27)25(16)3)24-18(29-19)15-11-8-12-26(15)21(28)22-13(2)14-9-6-5-7-10-14/h5-7,9-10,13,15H,4,8,11-12H2,1-3H3,(H,22,28)/t13-,15-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273019
PNG
((R)-2-[6-methyl-5-(3-methyl-[1,2,4]oxadiazol-5-yl)...)
Show SMILES Cc1noc(n1)-c1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C20H18N6O4S/c1-11-21-16(30-24-11)15-23-18-14(19(27)25(15)2)22-17(31-18)13-9-6-10-26(13)20(28)29-12-7-4-3-5-8-12/h3-5,7-8,13H,6,9-10H2,1-2H3/t13-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273020
PNG
((R)-2-(5-ethyl-6-methyl-7-oxo-6,7-dihydro[1,3]thia...)
Show SMILES CCc1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C19H20N4O3S/c1-3-14-20-17-15(18(24)22(14)2)21-16(27-17)13-10-7-11-23(13)19(25)26-12-8-5-4-6-9-12/h4-6,8-9,13H,3,7,10-11H2,1-2H3/t13-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273021
PNG
((R)-2-[5-methyl-7-oxo-6-(tetrahydro-2H-pyran-4-yl)...)
Show SMILES Cc1nc2sc(nc2c(=O)n1C1CCOCC1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C22H24N4O4S/c1-14-23-20-18(21(27)26(14)15-9-12-29-13-10-15)24-19(31-20)17-8-5-11-25(17)22(28)30-16-6-3-2-4-7-16/h2-4,6-7,15,17H,5,8-13H2,1H3/t17-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273022
PNG
((R)-2-[6-methyl-7-oxo-5-(tetrahydro-2H-pyran-4-yl)...)
Show SMILES Cc1cccc(OC(=O)N2CCC[C@@H]2c2nc3c(nc(C4CCOCC4)n(C)c3=O)s2)c1
Show InChI InChI=1S/C23H26N4O4S/c1-14-5-3-6-16(13-14)31-23(29)27-10-4-7-17(27)20-24-18-21(32-20)25-19(26(2)22(18)28)15-8-11-30-12-9-15/h3,5-6,13,15,17H,4,7-12H2,1-2H3/t17-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273023
PNG
((R)-2-[7-oxo-5-(propan-2-yl)-6,7-dihydro[1,3]thiaz...)
Show SMILES CC(C)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C19H20N4O3S/c1-11(2)15-21-16(24)14-18(22-15)27-17(20-14)13-9-6-10-23(13)19(25)26-12-7-4-3-5-8-12/h3-5,7-8,11,13H,6,9-10H2,1-2H3,(H,21,22,24)/t13-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273024
PNG
((R)-2-(7-oxo-5-phenyl-6,7-dihydro[1,3]thiazolo[5,4...)
Show SMILES O=C(Oc1ccccc1)N1CCC[C@@H]1c1nc2c(nc([nH]c2=O)-c2ccccc2)s1
Show InChI InChI=1S/C22H18N4O3S/c27-19-17-21(25-18(24-19)14-8-3-1-4-9-14)30-20(23-17)16-12-7-13-26(16)22(28)29-15-10-5-2-6-11-15/h1-6,8-11,16H,7,12-13H2,(H,24,25,27)/t16-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273025
PNG
((R)-2-[5-(2,4-difluorophenyl)-7-oxo-6,7-dihydro[1,...)
Show SMILES Fc1ccc(c(F)c1)-c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C22H16F2N4O3S/c23-12-8-9-14(15(24)11-12)18-26-19(29)17-21(27-18)32-20(25-17)16-7-4-10-28(16)22(30)31-13-5-2-1-3-6-13/h1-3,5-6,8-9,11,16H,4,7,10H2,(H,26,27,29)/t16-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273026
PNG
((R)-2-[5-(2-methylphenyl)-7-oxo-6,7-dihydro[1,3]th...)
Show SMILES Cc1ccccc1-c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C23H20N4O3S/c1-14-8-5-6-11-16(14)19-25-20(28)18-22(26-19)31-21(24-18)17-12-7-13-27(17)23(29)30-15-9-3-2-4-10-15/h2-6,8-11,17H,7,12-13H2,1H3,(H,25,26,28)/t17-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273027
PNG
((R)-2-[5-(4,4-difluorocyclohexyl)-7-oxo-6,7-dihydr...)
Show SMILES FC1(F)CCC(CC1)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C22H22F2N4O3S/c23-22(24)10-8-13(9-11-22)17-26-18(29)16-20(27-17)32-19(25-16)15-7-4-12-28(15)21(30)31-14-5-2-1-3-6-14/h1-3,5-6,13,15H,4,7-12H2,(H,26,27,29)/t15-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273028
PNG
((R)-2-{5-[1-(fluoromethyl)cyclopropyl]-7-oxo-6,7-d...)
Show SMILES FCC1(CC1)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C20H19FN4O3S/c21-11-20(8-9-20)18-23-15(26)14-17(24-18)29-16(22-14)13-7-4-10-25(13)19(27)28-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-11H2,(H,23,24,26)/t13-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273029
PNG
(N-{(R)-1-[5-(1-chlorocyclopropyl)-7-oxo-6,7-dihydr...)
Show SMILES C[C@@H](N(C)C(=O)Oc1ccccc1)c1nc2c(nc([nH]c2=O)C2(Cl)CC2)s1
Show InChI InChI=1S/C18H17ClN4O3S/c1-10(23(2)17(25)26-11-6-4-3-5-7-11)14-20-12-13(24)21-16(18(19)8-9-18)22-15(12)27-14/h3-7,10H,8-9H2,1-2H3,(H,21,22,24)/t10-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273030
PNG
((R)-2-[5-(1-cyanocyclopropyl)-7-oxo-6,7-dihydro[1,...)
Show SMILES Cc1cccc(OC(=O)N2CCC[C@@H]2c2nc3c(nc([nH]c3=O)C3(CC3)C#N)s2)c1
Show InChI InChI=1S/C21H19N5O3S/c1-12-4-2-5-13(10-12)29-20(28)26-9-3-6-14(26)17-23-15-16(27)24-19(25-18(15)30-17)21(11-22)7-8-21/h2,4-5,10,14H,3,6-9H2,1H3,(H,24,25,27)/t14-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273031
PNG
((R)-2-{5-[1-(methoxymethyl)cyclopropyl]-7-oxo-6,7-...)
Show SMILES COCC1(CC1)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C21H22N4O4S/c1-28-12-21(9-10-21)19-23-16(26)15-18(24-19)30-17(22-15)14-8-5-11-25(14)20(27)29-13-6-3-2-4-7-13/h2-4,6-7,14H,5,8-12H2,1H3,(H,23,24,26)/t14-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273032
PNG
(2-[(R)-1-(phenylacetyl)pyrrolidin-2-yl]-5-[1-(trif...)
Show SMILES FC(F)(F)C1(CC1)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Cc1ccccc1
Show InChI InChI=1S/C21H19F3N4O2S/c22-21(23,24)20(8-9-20)19-26-16(30)15-18(27-19)31-17(25-15)13-7-4-10-28(13)14(29)11-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-11H2,(H,26,27,30)/t13-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273033
PNG
(2-{(R)-1-[2-(3-methylphenyl)acetyl]pyrrolidin-2-yl...)
Show SMILES Cc1cccc(CC(=O)N2CCC[C@@H]2c2nc3c(nc([nH]c3=O)C3(CC3)C(F)(F)F)s2)c1
Show InChI InChI=1S/C22H21F3N4O2S/c1-12-4-2-5-13(10-12)11-15(30)29-9-3-6-14(29)18-26-16-17(31)27-20(28-19(16)32-18)21(7-8-21)22(23,24)25/h2,4-5,10,14H,3,6-9,11H2,1H3,(H,27,28,31)/t14-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273034
PNG
((R)-2-[5-(1-methylcyclopropoxy)-7-oxo-6,7-dihydro[...)
Show SMILES CC1(CC1)Oc1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C20H20N4O4S/c1-20(9-10-20)28-18-22-15(25)14-17(23-18)29-16(21-14)13-8-5-11-24(13)19(26)27-12-6-3-2-4-7-12/h2-4,6-7,13H,5,8-11H2,1H3,(H,22,23,25)/t13-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273035
PNG
((R)-2-[7-oxo-5-(2,2,2-trifluoroethoxy)-6,7-dihydro...)
Show SMILES FC(F)(F)COc1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C18H15F3N4O4S/c19-18(20,21)9-28-16-23-13(26)12-15(24-16)30-14(22-12)11-7-4-8-25(11)17(27)29-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,23,24,26)/t11-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273036
PNG
((R)-2-[5-(N,N-dimethylamino)-7-oxo-6,7-dihydro[1,3...)
Show SMILES CN(C)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C18H19N5O3S/c1-22(2)17-20-14(24)13-16(21-17)27-15(19-13)12-9-6-10-23(12)18(25)26-11-7-4-3-5-8-11/h3-5,7-8,12H,6,9-10H2,1-2H3,(H,20,21,24)/t12-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273037
PNG
((R)-2-[7-oxo-5-(piperidin-1-yl)-6,7-dihydro[1,3]th...)
Show SMILES O=C(Oc1ccccc1)N1CCC[C@@H]1c1nc2c(nc([nH]c2=O)N2CCCCC2)s1
Show InChI InChI=1S/C21H23N5O3S/c27-17-16-19(24-20(23-17)25-11-5-2-6-12-25)30-18(22-16)15-10-7-13-26(15)21(28)29-14-8-3-1-4-9-14/h1,3-4,8-9,15H,2,5-7,10-13H2,(H,23,24,27)/t15-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273038
PNG
((R)-2-[6-(2,4-dimethoxybenzyl)-5-ethyl-7-oxo-6,7-d...)
Show SMILES CCc1nc2sc(nc2c(=O)n1Cc1ccc(OC)cc1OC)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C27H28N4O5S/c1-4-22-28-25-23(26(32)31(22)16-17-12-13-19(34-2)15-21(17)35-3)29-24(37-25)20-11-8-14-30(20)27(33)36-18-9-6-5-7-10-18/h5-7,9-10,12-13,15,20H,4,8,11,14,16H2,1-3H3/t20-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273039
PNG
((R)-2-(5-ethyl-7-oxo-6,7-dihydro[1,3]thiazolo[5,4-...)
Show SMILES CCc1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C18H18N4O3S/c1-2-13-19-15(23)14-17(20-13)26-16(21-14)12-9-6-10-22(12)18(24)25-11-7-4-3-5-8-11/h3-5,7-8,12H,2,6,9-10H2,1H3,(H,19,20,23)/t12-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273040
PNG
((R)-2-[5-(3-methyloxetan-3-yl)-7-oxo-6,7-dihydro[1...)
Show SMILES CC1(COC1)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C20H20N4O4S/c1-20(10-27-11-20)18-22-15(25)14-17(23-18)29-16(21-14)13-8-5-9-24(13)19(26)28-12-6-3-2-4-7-12/h2-4,6-7,13H,5,8-11H2,1H3,(H,22,23,25)/t13-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273041
PNG
((R)-2-[5-(3-methyl-[1,2,4]oxadiazol-5-yl)-7-oxo-6,...)
Show SMILES Cc1noc(n1)-c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C19H16N6O4S/c1-10-20-16(29-24-10)14-22-15(26)13-18(23-14)30-17(21-13)12-8-5-9-25(12)19(27)28-11-6-3-2-4-7-11/h2-4,6-7,12H,5,8-9H2,1H3,(H,22,23,26)/t12-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273042
PNG
(2-[5-(2-fluoropropan-2-yl)-7-oxo-6,7-dihydro[1,3]t...)
Show SMILES CC(C)(F)c1nc2sc(nc2c(=O)[nH]1)N1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C18H18FN5O3S/c1-18(2,19)15-21-13(25)12-14(22-15)28-16(20-12)23-9-6-10-24(23)17(26)27-11-7-4-3-5-8-11/h3-5,7-8H,6,9-10H2,1-2H3,(H,21,22,25)
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273043
PNG
(2-[5-(2-fluoropropan-2-yl)-7-oxo-6,7-dihydro[1,3]t...)
Show SMILES Cc1cccc(OC(=O)N2CCCN2c2nc3c(nc([nH]c3=O)C(C)(C)F)s2)c1
Show InChI InChI=1S/C19H20FN5O3S/c1-11-6-4-7-12(10-11)28-18(27)25-9-5-8-24(25)17-21-13-14(26)22-16(19(2,3)20)23-15(13)29-17/h4,6-7,10H,5,8-9H2,1-3H3,(H,22,23,26)
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273044
PNG
(5-(2-fluoropropan-2-yl)-2-[2-(phenylacetyl)pyrazol...)
Show SMILES CC(C)(F)c1nc2sc(nc2c(=O)[nH]1)N1CCCN1C(=O)Cc1ccccc1
Show InChI InChI=1S/C19H20FN5O2S/c1-19(2,20)17-22-15(27)14-16(23-17)28-18(21-14)25-10-6-9-24(25)13(26)11-12-7-4-3-5-8-12/h3-5,7-8H,6,9-11H2,1-2H3,(H,22,23,27)
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273045
PNG
(5-(2-fluoropropan-2-yl)-2-{2-[2-(3-methylphenyl) a...)
Show SMILES Cc1cccc(CC(=O)N2CCCN2c2nc3c(nc([nH]c3=O)C(C)(C)F)s2)c1
Show InChI InChI=1S/C20H22FN5O2S/c1-12-6-4-7-13(10-12)11-14(27)25-8-5-9-26(25)19-22-15-16(28)23-18(20(2,3)21)24-17(15)29-19/h4,6-7,10H,5,8-9,11H2,1-3H3,(H,23,24,28)
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273046
PNG
((R)-2-[6-methyl-7-oxo-5-(propan-2-yl)-6,7-dihydro[...)
Show SMILES CC(C)c1nc2sc(nc2c(=O)n1C)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C20H22N4O3S/c1-12(2)16-22-18-15(19(25)23(16)3)21-17(28-18)14-10-7-11-24(14)20(26)27-13-8-5-4-6-9-13/h4-6,8-9,12,14H,7,10-11H2,1-3H3/t14-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273047
PNG
((R)-2-[6-(2-fluorophenyl)-4-oxo-4,5-dihydro[1,3]th...)
Show SMILES Fc1ccccc1-c1cc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C23H18FN3O3S/c24-16-10-5-4-9-15(16)17-13-19-20(21(28)25-17)26-22(31-19)18-11-6-12-27(18)23(29)30-14-7-2-1-3-8-14/h1-5,7-10,13,18H,6,11-12H2,(H,25,28)/t18-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273048
PNG
((R)-2-(4-oxo-6-trifluoromethyl-4,5-dihydro[1,3]thi...)
Show SMILES FC(F)(F)c1cc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C18H14F3N3O3S/c19-18(20,21)13-9-12-14(15(25)22-13)23-16(28-12)11-7-4-8-24(11)17(26)27-10-5-2-1-3-6-10/h1-3,5-6,9,11H,4,7-8H2,(H,22,25)/t11-/m1/s1
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n/an/a 390n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273049
PNG
((R)-2-[5-oxo-7-(propan-2-yl)-5H-[1,3,4]thiadiazolo...)
Show SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)Oc1ccc(F)cc1
Show InChI InChI=1S/C19H19FN4O3S/c1-11(2)14-10-16(25)24-18(21-14)28-17(22-24)15-4-3-9-23(15)19(26)27-13-7-5-12(20)6-8-13/h5-8,10-11,15H,3-4,9H2,1-2H3/t15-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273050
PNG
(2-[(R)-1-(phenylacetyl)pyrrolidin-2-yl]-7-(propan-...)
Show SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)Cc1ccccc1
Show InChI InChI=1S/C20H22N4O2S/c1-13(2)15-12-18(26)24-20(21-15)27-19(22-24)16-9-6-10-23(16)17(25)11-14-7-4-3-5-8-14/h3-5,7-8,12-13,16H,6,9-11H2,1-2H3/t16-/m1/s1
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n/an/a 980n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273051
PNG
(2-{(R)-1-[2-(4-fluorophenyl)acetyl]pyrrolidin-2-yl...)
Show SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)Cc1ccc(F)cc1
Show InChI InChI=1S/C20H21FN4O2S/c1-12(2)15-11-18(27)25-20(22-15)28-19(23-25)16-4-3-9-24(16)17(26)10-13-5-7-14(21)8-6-13/h5-8,11-12,16H,3-4,9-10H2,1-2H3/t16-/m1/s1
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n/an/a 2.20E+3n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273052
PNG
((R)-2-[5-oxo-7-(propan-2-yl)-5H-[1,3,4]thiadiazolo...)
Show SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C20H22N4O3S/c1-13(2)15-11-17(25)24-19(21-15)28-18(22-24)16-9-6-10-23(16)20(26)27-12-14-7-4-3-5-8-14/h3-5,7-8,11,13,16H,6,9-10,12H2,1-2H3/t16-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273053
PNG
(2-[(R)-1-(2-phenoxyacetyl)pyrrolidin-2-yl]-7-(prop...)
Show SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)COc1ccccc1
Show InChI InChI=1S/C20H22N4O3S/c1-13(2)15-11-17(25)24-20(21-15)28-19(22-24)16-9-6-10-23(16)18(26)12-27-14-7-4-3-5-8-14/h3-5,7-8,11,13,16H,6,9-10,12H2,1-2H3/t16-/m1/s1
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n/an/a 1.50E+3n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273054
PNG
((R)-2-(7-ethyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]p...)
Show SMILES CCc1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C18H18N4O3S/c1-2-12-11-15(23)22-17(19-12)26-16(20-22)14-9-6-10-21(14)18(24)25-13-7-4-3-5-8-13/h3-5,7-8,11,14H,2,6,9-10H2,1H3/t14-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273055
PNG
((R)-2-(6-ethyl-7-methyl-5-oxo-5H-[1,3,4]thiadiazol...)
Show SMILES CCc1c(C)nc2sc(nn2c1=O)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C19H20N4O3S/c1-3-14-12(2)20-18-23(17(14)24)21-16(27-18)15-10-7-11-22(15)19(25)26-13-8-5-4-6-9-13/h4-6,8-9,15H,3,7,10-11H2,1-2H3/t15-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273056
PNG
((R)-2-(5-oxo-6,7,8,9-tetrahydro-5H-[1,3,4]thiadiaz...)
Show SMILES O=C(Oc1ccccc1)N1CCC[C@@H]1c1nn2c(nc3CCCCc3c2=O)s1
Show InChI InChI=1S/C20H20N4O3S/c25-18-14-9-4-5-10-15(14)21-19-24(18)22-17(28-19)16-11-6-12-23(16)20(26)27-13-7-2-1-3-8-13/h1-3,7-8,16H,4-6,9-12H2/t16-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273057
PNG
((R)-2-[6-chloro-5-oxo-7-(propan-2-yl)-5H-[1,3,4]th...)
Show SMILES CC(C)c1nc2sc(nn2c(=O)c1Cl)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C19H19ClN4O3S/c1-11(2)15-14(20)17(25)24-18(21-15)28-16(22-24)13-9-6-10-23(13)19(26)27-12-7-4-3-5-8-12/h3-5,7-8,11,13H,6,9-10H2,1-2H3/t13-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273058
PNG
((R)-2-(7-fluoro-5-oxo-5H-[1,3,4]thiadiazolo[2,3-b]...)
Show SMILES Fc1ccc2nc3sc(nn3c(=O)c2c1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C20H15FN4O3S/c21-12-8-9-15-14(11-12)18(26)25-19(22-15)29-17(23-25)16-7-4-10-24(16)20(27)28-13-5-2-1-3-6-13/h1-3,5-6,8-9,11,16H,4,7,10H2/t16-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273059
PNG
((R)-N-benzyl-2-[5-oxo-7-(propan-2-yl)-5H-[1,3,4]th...)
Show SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)NCc1ccccc1
Show InChI InChI=1S/C20H23N5O2S/c1-13(2)15-11-17(26)25-20(22-15)28-18(23-25)16-9-6-10-24(16)19(27)21-12-14-7-4-3-5-8-14/h3-5,7-8,11,13,16H,6,9-10,12H2,1-2H3,(H,21,27)/t16-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273060
PNG
((R)-N-(2-chlorobenzyl)-2-[5-oxo-7-(propan-2-yl)-5H...)
Show SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)NCc1ccccc1Cl
Show InChI InChI=1S/C20H22ClN5O2S/c1-12(2)15-10-17(27)26-20(23-15)29-18(24-26)16-8-5-9-25(16)19(28)22-11-13-6-3-4-7-14(13)21/h3-4,6-7,10,12,16H,5,8-9,11H2,1-2H3,(H,22,28)/t16-/m1/s1
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MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair
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