Compile Data Set for Download or QSAR

Found 85 hits of ph data with Target = 'MAP kinase-interacting serine/threonine-protein kinase 1 (T344D)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211961 (US9290482, 1) Show SMILES COc1nccc2oc(cc12)-c1cnc2ccc(OC[C@H]3CNCCO3)nn12 Show InChI InChI=1S/C19H19N5O4/c1-25-19-13-8-16(28-15(13)4-5-21-19)14-10-22-17-2-3-18(23-24(14)17)27-11-12-9-20-6-7-26-12/h2-5,8,10,12,20H,6-7,9,11H2,1H3/t12-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211962 (US9290482, 2) Show SMILES COc1nccc2oc(cc12)-c1cnc2ccc(OCC3CNC3)nn12 Show InChI InChI=1S/C18H17N5O3/c1-24-18-12-6-15(26-14(12)4-5-20-18)13-9-21-16-2-3-17(22-23(13)16)25-10-11-7-19-8-11/h2-6,9,11,19H,7-8,10H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211963 (US9290482, 3) Show SMILES CN[C@H](C)COc1ccc2ncc(-c3cc4c(OC)nccc4o3)n2n1 Show InChI InChI=1S/C18H19N5O3/c1-11(19-2)10-25-17-5-4-16-21-9-13(23(16)22-17)15-8-12-14(26-15)6-7-20-18(12)24-3/h4-9,11,19H,10H2,1-3H3/t11-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211964 (US9290482, 4) Show SMILES C(Oc1ccc2ncc(-c3cc4cnccc4o3)n2n1)[C@H]1CNCCO1 Show InChI InChI=1S/C18H17N5O3/c1-2-18(25-11-13-9-20-5-6-24-13)22-23-14(10-21-17(1)23)16-7-12-8-19-4-3-15(12)26-16/h1-4,7-8,10,13,20H,5-6,9,11H2/t13-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	72	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211965 (US9290482, 5) Show SMILES C(Oc1ccc2ncc(-c3cc4ncccc4o3)n2n1)[C@H]1CNCCO1 Show InChI InChI=1S/C18H17N5O3/c1-2-15-13(20-5-1)8-16(26-15)14-10-21-17-3-4-18(22-23(14)17)25-11-12-9-19-6-7-24-12/h1-5,8,10,12,19H,6-7,9,11H2/t12-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211966 (US9290482, 6) Show SMILES C(C[C@@H]1CCCN1)Oc1ccc2ncc(-c3cc4cnccc4o3)n2n1 Show InChI InChI=1S/C19H19N5O2/c1-2-14(21-7-1)6-9-25-19-4-3-18-22-12-15(24(18)23-19)17-10-13-11-20-8-5-16(13)26-17/h3-5,8,10-12,14,21H,1-2,6-7,9H2/t14-/m0/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	132	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211967 (US9290482, 7) Show SMILES COc1nccc2oc(cc12)-c1cnc2ccc(O[C@@H](CNC3CC3)c3ccc(F)cc3)nn12 Show InChI InChI=1S/C25H22FN5O3/c1-32-25-18-12-21(33-20(18)10-11-27-25)19-13-29-23-8-9-24(30-31(19)23)34-22(14-28-17-6-7-17)15-2-4-16(26)5-3-15/h2-5,8-13,17,22,28H,6-7,14H2,1H3/t22-/m0/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	389	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211968 (US9290482, 8) Show SMILES COc1nccc2oc(cc12)-c1cnc2ccc(OCC3CCCCN3)nn12 Show InChI InChI=1S/C20H21N5O3/c1-26-20-14-10-17(28-16(14)7-9-22-20)15-11-23-18-5-6-19(24-25(15)18)27-12-13-4-2-3-8-21-13/h5-7,9-11,13,21H,2-4,8,12H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223020 (US9320737, I.1) Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(OCCCSC)nn12 Show InChI InChI=1S/C19H19N3O3S/c1-23-15-5-3-6-16-13(15)11-17(25-16)14-12-20-18-7-8-19(21-22(14)18)24-9-4-10-26-2/h3,5-8,11-12H,4,9-10H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223021 (US9320737, I.2) Show SMILES CSCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C18H17N3O2S/c1-24-10-4-9-22-18-8-7-17-19-12-14(21(17)20-18)16-11-13-5-2-3-6-15(13)23-16/h2-3,5-8,11-12H,4,9-10H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223022 (US9320737, I.3) Show SMILES CSCCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C19H19N3O2S/c1-25-11-5-4-10-23-19-9-8-18-20-13-15(22(18)21-19)17-12-14-6-2-3-7-16(14)24-17/h2-3,6-9,12-13H,4-5,10-11H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223023 (US9320737, I.4) Show SMILES CSCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C17H15N3O2S/c1-23-9-8-21-17-7-6-16-18-11-13(20(16)19-17)15-10-12-4-2-3-5-14(12)22-15/h2-7,10-11H,8-9H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223024 (US9320737, II.1) Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(OCCCS(C)=O)nn12 Show InChI InChI=1S/C19H19N3O4S/c1-24-15-5-3-6-16-13(15)11-17(26-16)14-12-20-18-7-8-19(21-22(14)18)25-9-4-10-27(2)23/h3,5-8,11-12H,4,9-10H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223025 (US9320737, II.2) Show SMILES CS(=O)CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C18H17N3O3S/c1-25(22)10-4-9-23-18-8-7-17-19-12-14(21(17)20-18)16-11-13-5-2-3-6-15(13)24-16/h2-3,5-8,11-12H,4,9-10H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223026 (US9320737, II.3) Show SMILES CS(=O)CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C19H19N3O3S/c1-26(23)11-5-4-10-24-19-9-8-18-20-13-15(22(18)21-19)17-12-14-6-2-3-7-16(14)25-17/h2-3,6-9,12-13H,4-5,10-11H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223027 (US9320737, II.4) Show SMILES CS(=O)CCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C17H15N3O3S/c1-24(21)9-8-22-17-7-6-16-18-11-13(20(16)19-17)15-10-12-4-2-3-5-14(12)23-15/h2-7,10-11H,8-9H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223028 (US9320737, III.1) Show SMILES CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C18H17N3O4S/c1-26(22,23)10-4-9-24-18-8-7-17-19-12-14(21(17)20-18)16-11-13-5-2-3-6-15(13)25-16/h2-3,5-8,11-12H,4,9-10H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223029 (US9320737, III.2) Show SMILES COc1ccc2oc(cc2c1)-c1cnc2ccc(OCCCS(C)(=O)=O)nn12 Show InChI InChI=1S/C19H19N3O5S/c1-25-14-4-5-16-13(10-14)11-17(27-16)15-12-20-18-6-7-19(21-22(15)18)26-8-3-9-28(2,23)24/h4-7,10-12H,3,8-9H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223030 (US9320737, III.3) Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(OCCCS(C)(=O)=O)nn12 Show InChI InChI=1S/C19H19N3O5S/c1-25-15-5-3-6-16-13(15)11-17(27-16)14-12-20-18-7-8-19(21-22(14)18)26-9-4-10-28(2,23)24/h3,5-8,11-12H,4,9-10H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223031 (US9320737, III.4) Show SMILES CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4cc(F)ccc4o3)n2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-27(23,24)8-2-7-25-18-6-5-17-20-11-14(22(17)21-18)16-10-12-9-13(19)3-4-15(12)26-16/h3-6,9-11H,2,7-8H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223032 (US9320737, III.5) Show SMILES CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4cc(Cl)ccc4o3)n2n1 Show InChI InChI=1S/C18H16ClN3O4S/c1-27(23,24)8-2-7-25-18-6-5-17-20-11-14(22(17)21-18)16-10-12-9-13(19)3-4-15(12)26-16/h3-6,9-11H,2,7-8H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223033 (US9320737, III.6) Show SMILES CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4cccc(F)c4o3)n2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-27(23,24)9-3-8-25-17-7-6-16-20-11-14(22(16)21-17)15-10-12-4-2-5-13(19)18(12)26-15/h2,4-7,10-11H,3,8-9H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223034 (US9320737, III.7) Show SMILES Cc1c(oc2ccccc12)-c1cnc2ccc(OCCCS(C)(=O)=O)nn12 Show InChI InChI=1S/C19H19N3O4S/c1-13-14-6-3-4-7-16(14)26-19(13)15-12-20-17-8-9-18(21-22(15)17)25-10-5-11-27(2,23)24/h3-4,6-9,12H,5,10-11H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223035 (US9320737, III.8) Show SMILES Cc1cccc2cc(oc12)-c1cnc2ccc(OCCCS(C)(=O)=O)nn12 Show InChI InChI=1S/C19H19N3O4S/c1-13-5-3-6-14-11-16(26-19(13)14)15-12-20-17-7-8-18(21-22(15)17)25-9-4-10-27(2,23)24/h3,5-8,11-12H,4,9-10H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223036 (US9320737, III.9) Show SMILES CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4c(F)cccc4o3)n2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-27(23,24)9-3-8-25-18-7-6-17-20-11-14(22(17)21-18)16-10-12-13(19)4-2-5-15(12)26-16/h2,4-7,10-11H,3,8-9H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223037 (US9320737, III.10) Show SMILES Cc1cc2ncc(-c3cc4ccccc4o3)n2nc1OCCCS(C)(=O)=O Show InChI InChI=1S/C19H19N3O4S/c1-13-10-18-20-12-15(17-11-14-6-3-4-7-16(14)26-17)22(18)21-19(13)25-8-5-9-27(2,23)24/h3-4,6-7,10-12H,5,8-9H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223038 (US9320737, III.11) Show SMILES CS(=O)(=O)CCCOc1nn2c(cnc2cc1-c1ccccc1)-c1cc2ccccc2o1 Show InChI InChI=1S/C24H21N3O4S/c1-32(28,29)13-7-12-30-24-19(17-8-3-2-4-9-17)15-23-25-16-20(27(23)26-24)22-14-18-10-5-6-11-21(18)31-22/h2-6,8-11,14-16H,7,12-13H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223039 (US9320737, III.12) Show SMILES COc1nccc2oc(cc12)-c1cnc2ccc(OCCCS(C)(=O)=O)nn12 Show InChI InChI=1S/C18H18N4O5S/c1-25-18-12-10-15(27-14(12)6-7-19-18)13-11-20-16-4-5-17(21-22(13)16)26-8-3-9-28(2,23)24/h4-7,10-11H,3,8-9H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223040 (US9320737, III.13) Show SMILES CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4cnccc4o3)n2n1 Show InChI InChI=1S/C17H16N4O4S/c1-26(22,23)8-2-7-24-17-4-3-16-19-11-13(21(16)20-17)15-9-12-10-18-6-5-14(12)25-15/h3-6,9-11H,2,7-8H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223041 (US9320737, III.14) Show SMILES CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4ncccc4o3)n2n1 Show InChI InChI=1S/C17H16N4O4S/c1-26(22,23)9-3-8-24-17-6-5-16-19-11-13(21(16)20-17)15-10-12-14(25-15)4-2-7-18-12/h2,4-7,10-11H,3,8-9H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223042 (US9320737, IV.1) Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(OCCCS(C)(=O)=NC(=O)C(F)(F)F)nn12 Show InChI InChI=1S/C21H19F3N4O5S/c1-31-15-5-3-6-16-13(15)11-17(33-16)14-12-25-18-7-8-19(26-28(14)18)32-9-4-10-34(2,30)27-20(29)21(22,23)24/h3,5-8,11-12H,4,9-10H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223043 (US9320737, IV.2) Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(OCCCS(C)(=N)=O)nn12 Show InChI InChI=1S/C19H20N4O4S/c1-25-15-5-3-6-16-13(15)11-17(27-16)14-12-21-18-7-8-19(22-23(14)18)26-9-4-10-28(2,20)24/h3,5-8,11-12,20H,4,9-10H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223044 (US9320737, IV.3) Show SMILES CS(=O)(CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC(=O)C(F)(F)F Show InChI InChI=1S/C20H17F3N4O4S/c1-32(29,26-19(28)20(21,22)23)10-4-9-30-18-8-7-17-24-12-14(27(17)25-18)16-11-13-5-2-3-6-15(13)31-16/h2-3,5-8,11-12H,4,9-10H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223045 (US9320737, IV.4) Show SMILES CS(=N)(=O)CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C18H18N4O3S/c1-26(19,23)10-4-9-24-18-8-7-17-20-12-14(22(17)21-18)16-11-13-5-2-3-6-15(13)25-16/h2-3,5-8,11-12,19H,4,9-10H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223047 (US9320737, IV.5) Show SMILES CS(=O)(CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC(=O)C(F)(F)F Show InChI InChI=1S/C21H19F3N4O4S/c1-33(30,27-20(29)21(22,23)24)11-5-4-10-31-19-9-8-18-25-13-15(28(18)26-19)17-12-14-6-2-3-7-16(14)32-17/h2-3,6-9,12-13H,4-5,10-11H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223048 (US9320737, IV.6) Show SMILES CS(=N)(=O)CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C19H20N4O3S/c1-27(20,24)11-5-4-10-25-19-9-8-18-21-13-15(23(18)22-19)17-12-14-6-2-3-7-16(14)26-17/h2-3,6-9,12-13,20H,4-5,10-11H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223049 (US9320737, IV.7) Show SMILES CS(=O)(CCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC(=O)C(F)(F)F Show InChI InChI=1S/C19H15F3N4O4S/c1-31(28,25-18(27)19(20,21)22)9-8-29-17-7-6-16-23-11-13(26(16)24-17)15-10-12-4-2-3-5-14(12)30-15/h2-7,10-11H,8-9H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223050 (US9320737, IV.8) Show SMILES CS(=O)(CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC#N Show InChI InChI=1S/C19H17N5O3S/c1-28(25,22-13-20)10-4-9-26-19-8-7-18-21-12-15(24(18)23-19)17-11-14-5-2-3-6-16(14)27-17/h2-3,5-8,11-12H,4,9-10H2,1H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223051 (US9320737, IV.9) Show SMILES COc1nccc2oc(cc12)-c1cnc2ccc(OCCCS(C)(=O)=NC#N)nn12 Show InChI InChI=1S/C19H18N6O4S/c1-27-19-13-10-16(29-15(13)6-7-21-19)14-11-22-17-4-5-18(24-25(14)17)28-8-3-9-30(2,26)23-12-20/h4-7,10-11H,3,8-9H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM223052 (US9320737, IV.10) Show SMILES COc1nccc2oc(cc12)-c1cnc2ccc(OCCCS(C)(=N)=O)nn12 Show InChI InChI=1S/C18H19N5O4S/c1-25-18-12-10-15(27-14(12)6-7-20-18)13-11-21-16-4-5-17(22-23(13)16)26-8-3-9-28(2,19)24/h4-7,10-11,19H,3,8-9H2,1-2H3	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9320737 (2016) BindingDB Entry DOI: 10.7270/Q22V2F00
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176745 (US9675612, 1 6-{[2-(Cyclopropylmethyl)[1,3]thiazol...) Show SMILES O=c1[nH]c2ccc(Nc3ncnc4sc(CC5CC5)nc34)cc2s1 Show InChI InChI=1S/C16H13N5OS2/c22-16-20-10-4-3-9(6-11(10)23-16)19-14-13-15(18-7-17-14)24-12(21-13)5-8-1-2-8/h3-4,6-8H,1-2,5H2,(H,20,22)(H,17,18,19)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176746 (US9675612, 2 6-[(2-Cyclobutyl[1,3]thiazolo[5,4-d]p...) Show SMILES O=c1[nH]c2ccc(Nc3ncnc4sc(nc34)C3CCC3)cc2s1 Show InChI InChI=1S/C16H13N5OS2/c22-16-20-10-5-4-9(6-11(10)23-16)19-13-12-15(18-7-17-13)24-14(21-12)8-2-1-3-8/h4-8H,1-3H2,(H,20,22)(H,17,18,19)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	87	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176747 (US9675612, 3 6-[(2-Cyclohexyl[1,3]thiazolo[5,4-d]p...) Show SMILES O=c1[nH]c2ccc(Nc3ncnc4sc(nc34)C3CCCCC3)cc2s1 Show InChI InChI=1S/C18H17N5OS2/c24-18-22-12-7-6-11(8-13(12)25-18)21-15-14-17(20-9-19-15)26-16(23-14)10-4-2-1-3-5-10/h6-10H,1-5H2,(H,22,24)(H,19,20,21)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	197	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176749 (US9675612, 4 2-Benzyl-N-(6-methoxy-1H-indazol-5-yl...) Show SMILES COc1cc2[nH]ncc2cc1Nc1ncnc2sc(Cc3ccccc3)nc12 Show InChI InChI=1S/C20H16N6OS/c1-27-16-9-14-13(10-23-26-14)8-15(16)24-19-18-20(22-11-21-19)28-17(25-18)7-12-5-3-2-4-6-12/h2-6,8-11H,7H2,1H3,(H,23,26)(H,21,22,24)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176754 (US9675612, 5 N-(6-Methoxy-1H-indazol-5-yl)-2-(meth...) Show SMILES COCc1nc2c(Nc3cc4cn[nH]c4cc3OC)ncnc2s1 Show InChI InChI=1S/C15H14N6O2S/c1-22-6-12-20-13-14(16-7-17-15(13)24-12)19-10-3-8-5-18-21-9(8)4-11(10)23-2/h3-5,7H,6H2,1-2H3,(H,18,21)(H,16,17,19)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176757 (US9675612, 7 6-[(2-Cyclohexyl[1,3]thiazolo[5,4-d]p...) Show SMILES COc1cc2[nH]c(=O)sc2cc1Nc1ncnc2sc(nc12)C1CCCCC1 Show InChI InChI=1S/C19H19N5O2S2/c1-26-13-7-12-14(27-19(25)23-12)8-11(13)22-16-15-18(21-9-20-16)28-17(24-15)10-5-3-2-4-6-10/h7-10H,2-6H2,1H3,(H,23,25)(H,20,21,22)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	354	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176761 (US9675612, 8 2-Cyclohexyl-N-(1H-indazol-5-yl)[1,3]...) Show SMILES C1CCC(CC1)c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1 Show InChI InChI=1S/C18H18N6S/c1-2-4-11(5-3-1)17-23-15-16(19-10-20-18(15)25-17)22-13-6-7-14-12(8-13)9-21-24-14/h6-11H,1-5H2,(H,21,24)(H,19,20,22)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176763 (US9675612, 9 2-(Cyclopropylmethyl)-N-(1H-indazol-5...) Show SMILES C(C1CC1)c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1 Show InChI InChI=1S/C16H14N6S/c1-2-9(1)5-13-21-14-15(17-8-18-16(14)23-13)20-11-3-4-12-10(6-11)7-19-22-12/h3-4,6-9H,1-2,5H2,(H,19,22)(H,17,18,20)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176766 (US9675612, 10 2-Cyclobutyl-N-(1H-indazol-5-yl)[1,3...) Show SMILES C1CC(C1)c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1 Show InChI InChI=1S/C16H14N6S/c1-2-9(3-1)15-21-13-14(17-8-18-16(13)23-15)20-11-4-5-12-10(6-11)7-19-22-12/h4-9H,1-3H2,(H,19,22)(H,17,18,20)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176767 (US9675612, 11 2-Benzyl-N-(1H-indazol-5-yl)[1,3]thi...) Show SMILES C(c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1)c1ccccc1 Show InChI InChI=1S/C19H14N6S/c1-2-4-12(5-3-1)8-16-24-17-18(20-11-21-19(17)26-16)23-14-6-7-15-13(9-14)10-22-25-15/h1-7,9-11H,8H2,(H,22,25)(H,20,21,23)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair

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