BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits of ph data with Target = 'Melanocortin receptor 3 (MC3R)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM230656
PNG
(US9340517, 105)
Show SMILES NC(=N)NCCC[C@H]1N[C@@H](CNC(=O)c2ccc3ccccc3c2)CCN(CC(c2ccccc2)c2ccccc2)C1=O
Show InChI InChI=1S/C35H40N6O2/c36-35(37)38-20-9-16-32-34(43)41(24-31(26-11-3-1-4-12-26)27-13-5-2-6-14-27)21-19-30(40-32)23-39-33(42)29-18-17-25-10-7-8-15-28(25)22-29/h1-8,10-15,17-18,22,30-32,40H,9,16,19-21,23-24H2,(H,39,42)(H4,36,37,38)/t30-,32-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.75E+3n/an/an/an/a7.44



Mimetica PTY LTD

US Patent


Assay Description
Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...


US Patent US9340517 (2016)


BindingDB Entry DOI: 10.7270/Q2PV6J8X
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM230659
PNG
(US9340517, 348)
Show SMILES CCC(CC)CN1CC[C@H](CNC(=O)\C=C\c2ccc(Cl)cc2)N[C@H](CCN2CCCCC2)C1=O
Show InChI InChI=1S/C28H43ClN4O2/c1-3-22(4-2)21-33-19-14-25(20-30-27(34)13-10-23-8-11-24(29)12-9-23)31-26(28(33)35)15-18-32-16-6-5-7-17-32/h8-13,22,25-26,31H,3-7,14-21H2,1-2H3,(H,30,34)/b13-10+/t25-,26-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.83E+3n/an/an/an/a7.44



Mimetica PTY LTD

US Patent


Assay Description
Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...


US Patent US9340517 (2016)


BindingDB Entry DOI: 10.7270/Q2PV6J8X
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM230658
PNG
(US9340517, 33)
Show SMILES Clc1ccc(\C=C\C(=O)NC[C@H]2CCN(CC(c3ccccc3)c3ccccc3)C(=O)[C@@H](CCN3CCCCC3)N2)cc1
Show InChI InChI=1S/C36H43ClN4O2/c37-31-17-14-28(15-18-31)16-19-35(42)38-26-32-20-25-41(36(43)34(39-32)21-24-40-22-8-3-9-23-40)27-33(29-10-4-1-5-11-29)30-12-6-2-7-13-30/h1-2,4-7,10-19,32-34,39H,3,8-9,20-27H2,(H,38,42)/b19-16+/t32-,34-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.50E+3n/an/an/an/a7.44



Mimetica PTY LTD

US Patent


Assay Description
Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...


US Patent US9340517 (2016)


BindingDB Entry DOI: 10.7270/Q2PV6J8X
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM230657
PNG
(US9340517, 64)
Show SMILES O=C(NC[C@H]1CCN(CC(c2ccccc2)c2ccccc2)C(=O)[C@@H](CCCN2CCCCC2)N1)c1ccc2ccccc2c1
Show InChI InChI=1S/C39H46N4O2/c44-38(34-21-20-30-13-8-9-18-33(30)27-34)40-28-35-22-26-43(39(45)37(41-35)19-12-25-42-23-10-3-11-24-42)29-36(31-14-4-1-5-15-31)32-16-6-2-7-17-32/h1-2,4-9,13-18,20-21,27,35-37,41H,3,10-12,19,22-26,28-29H2,(H,40,44)/t35-,37-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.24E+3n/an/an/an/a7.44



Mimetica PTY LTD

US Patent


Assay Description
Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...


US Patent US9340517 (2016)


BindingDB Entry DOI: 10.7270/Q2PV6J8X
More data for this
Ligand-Target Pair